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2007
24 Scopus citations

DNA palindromes with a modest arm length of ≳20 base pairs are a significant target for recombinant adeno-associated virus vector integration in the liver, muscles, and heart in mice

Inagaki, K., Lewis, S. M., Wu, X., Ma, C., Munroe, D. J., Fuess, S., Storm, T. A., Kay, M. A. & Nakai, H., Oct 1 2007, In : Journal of virology. 81, 20, p. 11290-11303 14 p.

Research output: Contribution to journalArticle

40 Scopus citations

Down-regulation of the trypanosomatid signal recognition particle affects the biogenesis of polytopic membrane proteins but not of signal peptide-containing proteins

Lustig, Y., Vagima, Y., Goldshmidt, H., Erlanger, A., Ozeri, V., Vince, J., McConville, M. J., Dwyer, D. M., Landfear, S. M. & Michaeli, S., Oct 1 2007, In : Eukaryotic Cell. 6, 10, p. 1865-1875 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Endotoxin preconditioning protects against the cytotoxic effects of TNFα after stroke: A novel role for TNFα in LPS-ischemic tolerance

Rosenzweig, H. L., Minami, M., Lessov, N. S., Coste, S. C., Stevens, S. L., Henshall, D. C., Meller, R., Simon, R. P. & Stenzel-Poore, M. P., Oct 1 2007, In : Journal of Cerebral Blood Flow and Metabolism. 27, 10, p. 1663-1674 12 p.

Research output: Contribution to journalArticle

119 Scopus citations

Enhanced pelvic responses to stressors in female CRF-overexpressing mice

Million, M., Wang, L., Stenzel-Poore, M. P., Coste, S. C., Yuan, P. Q., Lamy, C., Rivier, J., Buffington, T. & Taché, Y., Apr 1 2007, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 292, 4, p. R1429-R1438

Research output: Contribution to journalArticle

41 Scopus citations

Expression profiling identifies the CRH/CRH-R1 system as a modulator of neurovascular gene activity

Deussing, J. M., Kühne, C., Pütz, B., Panhuysen, M., Breu, J., Stenzel-Poore, M. P., Holsboer, F. & Wurst, W., Aug 24 2007, In : Journal of Cerebral Blood Flow and Metabolism. 27, 8, p. 1476-1495 20 p.

Research output: Contribution to journalArticle

21 Scopus citations

Galanin message-associated peptide suppresses growth and the budded-to-hyphal-form transition of Candida albicans

Rauch, I., Lundström, L., Hell, M., Sperl, W. & Kofler, B., Nov 1 2007, In : Antimicrobial agents and chemotherapy. 51, 11, p. 4167-4170 4 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Herpes simplex virus glycoproteins gB and gH function in fusion between the virion envelope and the outer nuclear membrane

Farnsworth, A., Wisner, T. W., Webb, M., Roller, R., Cohen, G., Eisenberg, R. & Johnson, D. C., Jun 12 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 24, p. 10187-10192 6 p.

Research output: Contribution to journalArticle

127 Scopus citations

HIV-1 Nef Assembles a Src Family Kinase-ZAP-70/Syk-PI3K Cascade to Downregulate Cell-Surface MHC-I

Hung, C. H., Thomas, L., Ruby, C. E., Atkins, K. M., Morris, N. P., Knight, Z. A., Scholz, I., Barklis, E., Weinberg, A. D., Shokat, K. M. & Thomas, G., Apr 19 2007, In : Cell Host and Microbe. 1, 2, p. 121-133 13 p.

Research output: Contribution to journalArticle

67 Scopus citations

Human immunodeficiency virus type 1 matrix protein assembles on membranes as a hexamer

Alfadhli, A., Huseby, D., Kapit, E., Colman, D. & Barklis, E., Feb 1 2007, In : Journal of virology. 81, 3, p. 1472-1478 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

IcsA surface presentation in Shigella flexneri requires the periplasmic chaperones DegP, Skp, and SurA

Purdy, G. E., Fisher, C. R. & Payne, S. M., Aug 1 2007, In : Journal of bacteriology. 189, 15, p. 5566-5573 8 p.

Research output: Contribution to journalArticle

86 Scopus citations

Ketone functionalized nitroxides: Synthesis, evaluation of N-alkoxyamine initiators, and derivatization of polymer termini

O'Bryan, G., Nilsen, A. & Braslau, R., Oct 30 2007, In : Macromolecules. 40, 22, p. 7848-7854 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Lipopolysaccharide preconditioning induces robust protection against brain injury resulting from deep hypothermic circulatory arrest

Hickey, E. J., You, X., Kaimaktchiev, V., Stenzel-Poore, M. & Ungerleider, R. M., Jun 1 2007, In : Journal of Thoracic and Cardiovascular Surgery. 133, 6, p. 1588-1596 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Lysosomal killing of Mycobacterium mediated by ubiquitin-derived peptides is enhanced by autophagy

Alonso, S., Pethe, K., Russell, D. G. & Purdy, G. E., Apr 3 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 14, p. 6031-6036 6 p.

Research output: Contribution to journalArticle

238 Scopus citations

Molecular genetic analysis of purine nucleobase transport in Leishmania major

Ortiz, D., Sanchez, M. A., Pierce, S., Herrmann, T., Kimblin, N., Archie Bouwer, H. G. & Landfear, S. M., Jun 1 2007, In : Molecular Microbiology. 64, 5, p. 1228-1243 16 p.

Research output: Contribution to journalArticle

30 Scopus citations

Nitroxide-mediated polymerization to form symmetrical ABA triblock copolymers from a bidirectional alkoxyamine initiator

Ruehl, J., Nilsen, A., Born, S., Thoniyot, P., Xu, L. P., Chen, S. & Braslau, R., Apr 24 2007, In : Polymer. 48, 9, p. 2564-2571 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Novel thyroxine derivatives, thyronamine and 3-iodothyronamine, induce transient hypothermia and marked neuroprotection against stroke injury

Doyle, K. P., Suchland, K. L., Ciesielski, T. M. P., Lessov, N. S., Grandy, D. K., Scanlan, T. S. & Stenzel-Poore, M. P., Sep 1 2007, In : Stroke. 38, 9, p. 2569-2576 8 p.

Research output: Contribution to journalArticle

78 Scopus citations

OX40 costimulation promotes persistence of cytomegalovirus-specific CD8 Tcells: A CD4-dependent mechanism

Humphreys, I. R., Loewendorf, A., De Trez, C., Schneider, K., Benedict, C. A., Munks, M. W., Ware, C. F. & Croft, M., Aug 15 2007, In : Journal of Immunology. 179, 4, p. 2195-2202 8 p.

Research output: Contribution to journalArticle

Open Access
69 Scopus citations

OX40-mediated differentiation to effector function requires IL-2 receptor signaling but not CD28, CD40, IL-12Rβ2, or T-bet

Williams, C. A., Murray, S. E., Weinberg, A. D. & Parker, D. C., Jun 15 2007, In : Journal of Immunology. 178, 12, p. 7694-7702 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Phenotypic characterization of a glucose transporter null mutant in Leishmania mexicana

Rodriguez-Contreras, D., Feng, X., Keeney, K. M., Bouwer, H. G. A. & Landfear, S. M., May 1 2007, In : Molecular and Biochemical Parasitology. 153, 1, p. 9-18 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Preconditioning reprograms the response to ischemic injury and primes the emergence of unique endogenous neuroprotective phenotypes: A speculative synthesis

Stenzel-Poore, M. P., Stevens, S. L., King, J. S. & Simon, R. P., Feb 1 2007, In : Stroke. 38, 2 PART 2, p. 680-685 6 p.

Research output: Contribution to journalArticle

158 Scopus citations

Preformed CD40 ligand exists in secretory lysosomes in effector and memory CD4+ T cells and is quickly expressed on the cell surface in an antigen-specific manner

Koguchi, Y., Thauland, T. J., Slifka, M. K. & Parker, D. C., Oct 1 2007, In : Blood. 110, 7, p. 2520-2527 8 p.

Research output: Contribution to journalArticle

52 Scopus citations

Selective killing of the human malaria parasite Plasmodium falciparum by a benzylthiazolium dye

Kelly, J. X., Winter, R. W., Braun, T. P., Osei-Agyemang, M., Hinrichs, D. J. & Riscoe, M. K., Jun 1 2007, In : Experimental Parasitology. 116, 2, p. 103-110 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Strategies for selective priming of memory B cells

Raman, V. S., Lind, E. F., Benson, M. J. & Noelle, R. J., Apr 15 2007, In : Immunology Letters. 109, 2, p. 93-100 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
32 Scopus citations

Structures of 5-methylthioribose kinase reveal substrate specificity and unusual mode of nucleotide binding

Ku, S. Y., Yip, P., Cornell, K. A., Riscoe, M. K., Behr, J. B., Guillerm, G. & Howell, P. L., Jul 27 2007, In : Journal of Biological Chemistry. 282, 30, p. 22195-22206 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Study of the role of CCR5 in a mouse model of intranasal challenge with Yersinia pestis

Styer, K. L., Click, E. M., Hopkins, G. W., Frothingham, R. & Aballay, A., Jul 1 2007, In : Microbes and Infection. 9, 9, p. 1135-1138 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Sultam thiourea inhibition of West Nile virus

Barklis, E., Still, A., Sabri, M. I., Hirsch, A. J., Nikolich-Zugich, J., Brien, J., Dhenub, T. C., Scholz, I. & Alfadhli, A., Jul 1 2007, In : Antimicrobial agents and chemotherapy. 51, 7, p. 2642-2645 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

TCR/CD28-stimulated actin dynamics are required for NFAT1-mediated transcription of c-rel leading to CD28 response element activation

Nolz, J. C., Fernandez-Zapico, M. E. & Billadeau, D. D., Jul 15 2007, In : Journal of Immunology. 179, 2, p. 1104-1112 9 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

The in vivo function of a noncanonical TRAF2-binding domain in the C-terminus of CD40 in driving B-cell growth and differentiation

Lu, L. F., Ahonen, C. L., Lind, E. F., Raman, V. S., Cook, W. J., Lin, G. L. & Noelle, R. J., Jul 1 2007, In : Blood. 110, 1, p. 193-200 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

The Legionella pneumophila IcmSW complex interacts with multiple Dot/Icm effectors to facilitate type IV translocation

Cambronne, E. D. & Roy, C. R., Dec 1 2007, In : PLoS pathogens. 3, 12, p. 1837-1848 12 p.

Research output: Contribution to journalArticle

68 Scopus citations

The role of DNA-PKcs and artemis in opening viral DNA hairpin termini in various tissues in mice

Inagaki, K., Ma, C., Storm, T. A., Kay, M. A. & Nakai, H., Oct 1 2007, In : Journal of virology. 81, 20, p. 11304-11321 18 p.

Research output: Contribution to journalArticle

47 Scopus citations

The role of NKG2D signaling in inhibition of cytotoxic T-lymphocyte lysis by the murine cytomegalovirus immunoevasin m152/gp40

Pinto, A. K., Jamieson, A. M., Raulet, D. H. & Hill, A. B., Nov 1 2007, In : Journal of virology. 81, 22, p. 12564-12571 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Ubiquitin trafficking to the lysosome: Keeping the house tidy and getting rid of unwanted guests

Purdy, G. E. & Russell, D. G., Jan 1 2007, In : Autophagy. 3, 4, p. 399-401 3 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Viral interference with antigen presentation does not alter acute or chronic CD8 T cell immunodominance in murine cytomegalovirus infection

Munks, M. W., Pinto, A. K., Doom, C. M. & Hill, A. B., Jun 1 2007, In : Journal of Immunology. 178, 11, p. 7235-7241 7 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

WAVE2 regulates high-affinity integrin binding by recruiting vinculin and talin to the immunological synapse

Nolz, J. C., Medeiros, R. B., Mitchell, J. S., Zhu, P., Freedman, B. D., Shimizu, Y. & Billadeau, D. D., Sep 1 2007, In : Molecular and cellular biology. 27, 17, p. 5986-6000 15 p.

Research output: Contribution to journalArticle

73 Scopus citations
2006

A chloroquine-like molecule designed to reverse resistance in Plasmodium falciparum

Burgess, S. J., Selzer, A., Kelly, J. X., Smilkstein, M. J., Riscoe, M. K. & Peyton, D. H., Sep 7 2006, In : Journal of Medicinal Chemistry. 49, 18, p. 5623-5625 3 p.

Research output: Contribution to journalArticle

106 Scopus citations

Antigen-specific accumulation of naïve, memory and effector CD4 T cells during anterior uveitis monitored by intravital microscopy

Dullforce, P. A., Seitz, G. W., Garman, K. L., Michael, J. A., Crespo, S. M., Fleischman, R. J., Planck, S. R., Parker, D. C. & Rosenbaum, J. T., Jan 1 2006, In : Cellular Immunology. 239, 1, p. 49-60 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

B cells expressing a natural polyreactive autoantibody have a distinct phenotype and are overrepresented in immunoglobulin heavy chain transgenic mice

Tian, Q., Beardall, M., Xu, Y., Li, J., Parker, D. C., Casanova, N., Bakke, A. C. & Chen, C., Aug 15 2006, In : Journal of Immunology. 177, 4, p. 2412-2422 11 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Cellular and molecular requirements for association of the murine cytomegalovirus protein m4/gp34 with major histocompatibility complex class I molecules

Lu, X., Kavanagh, D. G. & Hill, A. B., Jun 1 2006, In : Journal of virology. 80, 12, p. 6048-6055 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Characterization of the role of very late expression factor 1 in baculovirus capsid structure and DNA processing

Vanarsdall, A. L., Okano, K. & Rohrmann, G. F., Feb 1 2006, In : Journal of virology. 80, 4, p. 1724-1733 10 p.

Research output: Contribution to journalArticle

85 Scopus citations

Comprehensive examination of charged intramembrane residues in a nucleoside transporter

Valdés, R., Liu, W., Ullman, B. & Landfear, S. M., Aug 11 2006, In : Journal of Biological Chemistry. 281, 32, p. 22647-22655 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Coordinated function of murine cytomegalovirus genes completely inhibits CTL lysis

Pinto, A. K., Munks, M. W., Koszinowski, U. H. & Hill, A. B., Sep 1 2006, In : Journal of Immunology. 177, 5, p. 3225-3234 10 p.

Research output: Contribution to journalArticle

Open Access
46 Scopus citations

Corticotropin-releasing factor receptor type 2-deficient mice display impaired coping behaviors during stress

Coste, S. C., Heard, A. D., Phillips, T. J. & Stenzel-Poore, M. P., Mar 1 2006, In : Genes, Brain and Behavior. 5, 2, p. 131-138 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Evaluation and lead optimization of anti-malarial acridones

Winter, R. W., Kelly, J. X., Smilkstein, M. J., Dodean, R., Bagby, G. C., Rathbun, R. K., Levin, J. I., Hinrichs, D. & Riscoe, M. K., Sep 1 2006, In : Experimental Parasitology. 114, 1, p. 47-56 10 p.

Research output: Contribution to journalArticle

70 Scopus citations

Four distinct patterns of memory CD8 T cell responses to chronic murine cytomegalovirus infection

Munks, M. W., Cho, K. S., Pinto, A. K., Sierro, S., Klenerman, P. & Hill, A. B., Jul 1 2006, In : Journal of Immunology. 177, 1, p. 450-458 9 p.

Research output: Contribution to journalArticle

Open Access
175 Scopus citations

Functional characterization and subcellular localization of the three malate dehydrogenase isozymes in Leishmania spp.

Leroux, A., Fleming-Canepa, X., Aranda, A., Maugeri, D., Cazzulo, J. J., Sánchez, M. A. & Nowicki, C., Sep 1 2006, In : Molecular and Biochemical Parasitology. 149, 1, p. 74-85 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

GATA transcription factor required for immunity to bacterial and fungal pathogens

Kerry, S., TeKippe, M., Gaddis, N. C. & Aballay, A., Dec 20 2006, In : PloS one. 1, 1, e77.

Research output: Contribution to journalArticle

62 Scopus citations

Genome-wide analysis reveals a highly diverse CD8 T cell response to murine cytomegalovirus

Munks, M. W., Gold, M. C., Zajac, A. L., Doom, C. M., Morello, C. S., Spector, D. H. & Hill, A. B., Mar 15 2006, In : Journal of Immunology. 176, 6, p. 3760-3766 7 p.

Research output: Contribution to journalArticle

Open Access
105 Scopus citations
130 Scopus citations