Research Output 1969 2019

Filter
Article
2005
40 Citations (Scopus)

Regulation of the small GTPase Rap1 and extracellular signal-regulated kinases by the costimulatory molecule CTLA-4

Dillon, T. J., Carey, K. D., Wetzel, S. A., Parker, D. & Stork, P., May 2005, In : Molecular and Cellular Biology. 25, 10, p. 4117-4128 12 p.

Research output: Contribution to journalArticle

Monomeric GTP-Binding Proteins
Extracellular Signal-Regulated MAP Kinases
T-Lymphocytes
Transgenic Mice
Interleukin-2
304 Citations (Scopus)

T cells and viral persistence: Lessons from diverse infections

Klenerman, P. & Hill, A., Sep 2005, In : Nature Immunology. 6, 9, p. 873-879 7 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Infection
Virus Diseases
Cytomegalovirus
Human Herpesvirus 4
51 Citations (Scopus)

The extracellular domain of herpes simplex virus gE is indispensable for efficient cell-to-cell spread: Evidence for gE/gI receptors

Polcicova, K., Goldsmith, K., Rainish, B. L., Wisner, T. W. & Johnson, D., Sep 2005, In : Journal of Virology. 79, 18, p. 11990-12001 12 p.

Research output: Contribution to journalArticle

herpes simplex
Simplexvirus
viruses
receptors
cells
1102 Citations (Scopus)

The genome of the African trypanosome Trypanosoma brucei

Berriman, M., Ghedin, E., Hertz-Fowler, C., Blandin, G., Renauld, H., Bartholomeu, D. C., Lennard, N. J., Caler, E., Hamlin, N. E., Haas, B., Böhme, U., Hannick, L., Aslett, M. A., Shallom, J., Marcello, L., Hou, L., Wickstead, B., Alsmark, U. C. M., Arrowsmith, C., Atkin, R. J. & 82 others, Barron, A. J., Bringaud, F., Brooks, K., Carrington, M., Cherevach, I., Chillingworth, T. J., Churcher, C., Clark, L. N., Corton, C. H., Cronin, A., Davies, R. M., Doggett, J., Djikeng, A., Feldblyum, T., Field, M. C., Fraser, A., Goodhead, I., Hance, Z., Harper, D., Harris, B. R., Hauser, H., Hostetler, J., Ivens, A., Jagels, K., Johnson, D., Johnson, J., Jones, K., Kerhornou, A. X., Koo, H., Larke, N., Landfear, S., Larkin, C., Leech, V., Line, A., Lord, A., MacLeod, A., Mooney, P. J., Moule, S., Martin, D. M. A., Morgan, G. W., Mungall, K., Norbertczak, H., Ormond, D., Pai, G., Peacock, C. S., Peterson, J., Quail, M. A., Rabbinowitsch, E., Rajandream, M. A., Reitter, C., Salzberg, S. L., Sanders, M., Schobel, S., Sharp, S., Simmonds, M., Simpson, A. J., Tallon, L., Turner, C. M. R., Tait, A., Tivey, A. R., Van Aken, S., Walker, D., Wanless, D., Wang, S., White, B., White, O., Whitehead, S., Woodward, J., Wortman, J., Adams, M. D., Embley, T. M., Gull, K., Ullu, E., Barry, J. D., Fairlamb, A. H., Opperdoes, F., Barrell, B. G., Donelson, J. E., Hall, N., Fraser, C. M., Melville, S. E. & El-Sayed, N. M., Jul 15 2005, In : Science. 309, 5733, p. 416-422 7 p.

Research output: Contribution to journalArticle

Trypanosoma brucei brucei
Trypanosomiasis
Genome
Leishmania major
Pseudogenes
31 Citations (Scopus)

Viral interference with antigen presentation to CD8+ T cells: Lessons from cytomegalovirus

Pinto, A. K. & Hill, A., 2005, In : Viral Immunology. 18, 3, p. 434-444 11 p.

Research output: Contribution to journalArticle

Viral Interference
Antigen Presentation
Cytomegalovirus
Viruses
T-Lymphocytes
44 Citations (Scopus)

Virus particle core defects caused by mutations in the human immunodeficiency virus capsid N-terminal domain

Scholz, I., Arvidson, B., Huseby, D. & Barklis, E., Feb 2005, In : Journal of Virology. 79, 3, p. 1470-1479 10 p.

Research output: Contribution to journalArticle

capsid
Capsid
Human immunodeficiency virus
virion
histidine
2004
47 Citations (Scopus)

4-1BB and OX40 stimulation enhance CD8 and CD4 T-cell responses to a DNA prime, poxvirus boost vaccine

Munks, M., Mourich, D. V., Mittler, R. S., Weinberg, A. D. & Hill, A., Aug 2004, In : Immunology. 112, 4, p. 559-566 8 p.

Research output: Contribution to journalArticle

Poxviridae
Vaccines
T-Lymphocytes
DNA
Tumor Necrosis Factor Receptors
21 Citations (Scopus)

A novel purine nucleoside transporter whose expression is up-regulated in the short stumpy form of the Trypanosoma brucei life cycle

Sanchez, M., Drutman, S., Van Ampting, M., Matthews, K. & Landfear, S., Aug 2004, In : Molecular and Biochemical Parasitology. 136, 2, p. 265-272 8 p.

Research output: Contribution to journalArticle

Nucleoside Transport Proteins
Purine Nucleosides
Trypanosoma brucei brucei
Life Cycle Stages
Purines
36 Citations (Scopus)

APCs in the anterior uveal tract do not migrate to draining lymph nodes

Dullforce, P. A., Garman, K. L., Seitz, G. W., Fleischmann, R. J., Crespo, S. M., Planck, S., Parker, D. & Rosenbaum, J. J., Jun 1 2004, In : Journal of Immunology. 172, 11, p. 6701-6708 8 p.

Research output: Contribution to journalArticle

Lymph Nodes
Anterior Chamber
Video Microscopy
Lymphatic Vessels
Conjunctiva
66 Citations (Scopus)

A signal through OX40 (CD134) allows anergic, autoreactive T cells to acquire effector cell functions

Lathrop, S. K., Huddleston, C. A., Dullforce, P. A., Montfort, M. J., Weinberg, A. D. & Parker, D., Jun 1 2004, In : Journal of Immunology. 172, 11, p. 6735-6743 9 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Cytokines
Peripheral Tolerance
Self Tolerance
Ionomycin
34 Citations (Scopus)

Corticotropin-releasing factor overexpression decreases ethanol drinking and increases sensitivity to the sedative effects of ethanol

Palmer, A. A., Sharpe, A. L., Burkhart-Kasch, S., McKinnon, C. S., Coste, S. C., Stenzel-Poore, M. & Phillips, T., Nov 2004, In : Psychopharmacology. 176, 3-4, p. 386-397 12 p.

Research output: Contribution to journalArticle

Corticotropin-Releasing Hormone
Hypnotics and Sedatives
Drinking
Ethanol
Transgenic Mice
10 Citations (Scopus)

Crystallization and preliminary X-ray analysis of 5′-methylthioribose kinase from Bacillus subtilis and Arabidopsis thaliana

Ku, S. Y., Yip, P., Cornell, K. A., Riscoe, M. & Howell, P. L., Jan 2004, In : Acta Crystallographica Section D: Biological Crystallography. 60, 1, p. 116-119 4 p.

Research output: Contribution to journalArticle

Bacillus
X ray analysis
Bacilli
Crystallization
Bacillus subtilis
2 Citations (Scopus)

CyQUANT cell proliferation assay as a fluorescence-based method for in vitro screening of antimalarial activity

Sriwilaijaroen, N., Kelly, J. X., Riscoe, M. & Wilairat, P., Dec 2004, In : Southeast Asian Journal of Tropical Medicine and Public Health. 35, 4, p. 840-844 5 p.

Research output: Contribution to journalArticle

Antimalarials
Fluorescence
Cell Proliferation
Ethanolamine
Chloroquine
174 Citations (Scopus)

Endotoxin preconditioning prevents cellular inflammatory response during ischemic neuroprotection in mice

Rosenzweig, H., Lessov, N. S., Henshall, D. C., Minami, M., Simon, R. P. & Stenzel-Poore, M., Nov 2004, In : Stroke. 35, 11, p. 2576-2581 6 p.

Research output: Contribution to journalArticle

Endotoxins
Lipopolysaccharides
Middle Cerebral Artery Infarction
Brain
Microglia
31 Citations (Scopus)

Functional expression and characterization of a purine nucleobase transporter gene from Leishmania major

Sanchez, M., Tryon, R., Pierce, S., Vasudevan, G. & Landfear, S., Jan 2004, In : Molecular Membrane Biology. 21, 1, p. 11-18 8 p.

Research output: Contribution to journalArticle

Nucleoside Transport Proteins
Leishmania major
Genes
Hypoxanthine
Xanthine
106 Citations (Scopus)

GABA Release from Proopiomelanocortin Neurons

Hentges, S. T., Nishiyama, M., Overstreet, L. S., Stenzel-Poore, M., Williams, J. & Low, M. J., Feb 18 2004, In : Journal of Neuroscience. 24, 7, p. 1578-1583 6 p.

Research output: Contribution to journalArticle

Pro-Opiomelanocortin
gamma-Aminobutyric Acid
Neurons
Neurotransmitter Agents
Eating
21 Citations (Scopus)

Gene expression profiles highlight adaptive brain mechanisms in corticotropin releasing factor overexpressing mice

Peeters, P. J., Fierens, F. L. P., Van Den Wyngaert, I., Goehlmann, H. W., Swagemakers, S. M., Kass, S. U., Langlois, X., Pullan, S., Stenzel-Poore, M. & Steckler, T., Oct 22 2004, In : Molecular Brain Research. 129, 1-2, p. 135-150 16 p.

Research output: Contribution to journalArticle

Corticotropin-Releasing Hormone
Transcriptome
Brain
Neurotensin Receptors
Glucocorticoids
67 Citations (Scopus)

Genomics of preconditioning

Stenzel-Poore, M., Stevens, S. L. & Simon, R. P., Nov 2004, In : Stroke. 35, 11 SUPPL. 1, p. 2683-2686 4 p.

Research output: Contribution to journalArticle

Genomics
Stroke
Ischemic Preconditioning
Genes
Middle Cerebral Artery Infarction
62 Citations (Scopus)

Murine cytomegalovirus interference with antigen presentation has little effect on the size or the effector memory phenotype of the CD8 T cell response

Gold, M., Munks, M., Wagner, M., McMahon, C. W., Kelly, A., Kavanagh, D. G., Slifka, M., Koszinowski, U. H., Raulet, D. H. & Hill, A., Jun 1 2004, In : Journal of Immunology. 172, 11, p. 6944-6953 10 p.

Research output: Contribution to journalArticle

Muromegalovirus
Antigen Presentation
T-Lymphocytes
Phenotype
Viruses
89 Citations (Scopus)

Nucleoside and nucleobase transporters in parasitic protozoa

Landfear, S., Ullman, B., Carter, N. & Sanchez, M., Apr 2004, In : Eukaryotic Cell. 3, 2, p. 245-254 10 p.

Research output: Contribution to journalArticle

adenosine monophosphate
nucleosides
drug resistance
purines
Protozoa
16 Citations (Scopus)

Overproduction of corticotropin-releasing hormone blocks germinal center formation: Role of corticosterone and impaired follicular dendritic cell networks

Murray, S., Rosenzweig, H., Johnson, M., Huising, M. O., Sawicki, K. & Stenzel-Poore, M., Nov 2004, In : Journal of Neuroimmunology. 156, 1-2, p. 31-41 11 p.

Research output: Contribution to journalArticle

Follicular Dendritic Cells
Germinal Center
Corticotropin-Releasing Hormone
Corticosterone
Transgenic Mice
51 Citations (Scopus)

Redistribution of cellular and herpes simplex virus proteins from the trans-Golgi network to cell junctions without enveloped capsids

Wisner, T. W. & Johnson, D., Nov 2004, In : Journal of Virology. 78, 21, p. 11519-11535 17 p.

Research output: Contribution to journalArticle

intercellular junctions
trans-Golgi Network
herpes simplex
Intercellular Junctions
capsid
24 Citations (Scopus)

Sequences required for the flagellar targeting of an integral membrane protein

Nasser, M. I. A. & Landfear, S., May 2004, In : Molecular and Biochemical Parasitology. 135, 1, p. 89-100 12 p.

Research output: Contribution to journalArticle

Facilitative Glucose Transport Proteins
Leishmania enriettii
Membrane Proteins
Membrane Transport Proteins
Amino Acid Sequence
586 Citations (Scopus)

Simple and Inexpensive Fluorescence-Based Technique for High-Throughput Antimalarial Drug Screening

Smilkstein, M., Sriwilaijaroen, N., Kelly, J. X., Wilairat, P. & Riscoe, M., May 2004, In : Antimicrobial Agents and Chemotherapy. 48, 5, p. 1803-1806 4 p.

Research output: Contribution to journalArticle

Preclinical Drug Evaluations
Antimalarials
Fluorescence
Parasites
Equipment Safety
28 Citations (Scopus)

Structural Comparison of MTA Phosphorylase and MTA/AdoHcy Nucleosidase Explains Substrate Preferences and Identifies Regions Exploitable for Inhibitor Design

Lee, J. E., Settembre, E. C., Cornell, K. A., Riscoe, M., Sufrin, J. R., Ealick, S. E. & Howell, P. L., May 11 2004, In : Biochemistry. 43, 18, p. 5159-5169 11 p.

Research output: Contribution to journalArticle

adenosylhomocysteine nucleosidase
Pemetrexed
N-Glycosyl Hydrolases
Substrates
Phosphorylases
33 Citations (Scopus)

Transmembrane domain 5 of the LdNT1.1 nucleoside transporter is an amphipathic helix that forms part of the nucleoside translocation pathway

Valdés, R., Vasudevan, G., Conklin, D. & Landfear, S., Jun 1 2004, In : Biochemistry. 43, 21, p. 6793-6802 10 p.

Research output: Contribution to journalArticle

Nucleoside Transport Proteins
Nucleosides
Cysteine
Adenosine
Uridine
49 Citations (Scopus)

α lipoic acid inhibits human T-cell migration: Implications for multiple sclerosis

Marracci, G., McKeon, G. P., Marquardt, W. E., Winter, R. W., Riscoe, M. & Bourdette, D., Nov 1 2004, In : Journal of Neuroscience Research. 78, 3, p. 362-370 9 p.

Research output: Contribution to journalArticle

Thioctic Acid
Oxidants
Multiple Sclerosis
Cell Movement
Jurkat Cells
2003
27 Citations (Scopus)

Activation of the CRF 2 receptor modulates skeletal muscle mass under physiological and pathological conditions

Hinkle, R. T., Donnelly, E., Cody, D. B., Samuelsson, S., Lange, J. S., Bauer, M. B., Tarnopolsky, M., Sheldon, R. J., Coste, S. C., Tobar, E., Stenzel-Poore, M. & Isfort, R. J., Oct 1 2003, In : American Journal of Physiology - Endocrinology and Metabolism. 285, 4 48-4

Research output: Contribution to journalArticle

Muscle
Skeletal Muscle
Chemical activation
Adrenal Cortex Hormones
Corticotropin-Releasing Hormone Receptors
12 Citations (Scopus)

Analysis of the retrovirus capsid interdomain linker region

Arvidson, B., Seeds, J., Webb, M., Finlay, L. & Barklis, E., Mar 30 2003, In : Virology. 308, 1, p. 166-177 12 p.

Research output: Contribution to journalArticle

Capsid
Retroviridae
Moloney murine leukemia virus
Human Immunodeficiency Virus Proteins
Viral Structural Proteins
17 Citations (Scopus)

Antileishmanial drug development: Exploitation of parasite heme dependency

Kelly, J. X., Ignatushchenko, M. V., Bouwer, H. G., Peyton, D. H., Hinrichs, D. J., Winter, R. W. & Riscoe, M., Jan 2003, In : Molecular and Biochemical Parasitology. 126, 1, p. 43-49 7 p.

Research output: Contribution to journalArticle

Heme
Parasites
Xanthones
Pharmaceutical Preparations
Leishmania
151 Citations (Scopus)

Antiviral Inhibition of the HIV-1 capsid protein

Tang, C., Loeliger, E., Kinde, I., Kyere, S., Mayo, K., Barklis, E., Sun, Y., Huang, M. & Summers, M. F., Apr 11 2003, In : Journal of Molecular Biology. 327, 5, p. 1013-1020 8 p.

Research output: Contribution to journalArticle

Capsid
Capsid Proteins
Antiviral Agents
HIV-1
Virion
24 Citations (Scopus)

Ectopic B-Raf expression enhances extracellular signal-regulated kinase (ERK) signaling in T cells and prevents antigen-presenting cell-induced anergy

Dillon, T. J., Karpitski, V., Wetzel, S. A., Parker, D., Shaw, A. S. & Stork, P., Sep 19 2003, In : Journal of Biological Chemistry. 278, 38, p. 35940-35949 10 p.

Research output: Contribution to journalArticle

T-cells
Extracellular Signal-Regulated MAP Kinases
Antigen-Presenting Cells
Chemical activation
T-Lymphocytes
30 Citations (Scopus)

Effective inhibition of Kb- and Db-restricted antigen presentation in primary macrophages by murine cytomegalovirus

LoPiccolo, D. M., Gold, M., Kavanagh, D. G., Wagner, M., Koszinowski, U. H. & Hill, A., Jan 2003, In : Journal of Virology. 77, 1, p. 301-308 8 p.

Research output: Contribution to journalArticle

Muromegalovirus
Cytomegalovirus
antigen presentation
Antigen Presentation
immune evasion
336 Citations (Scopus)

Effect of ischaemic preconditioning on genomic response to cerebral ischaemia: Similarity to neuroprotective strategies in hibernation and hypoxia-tolerant states

Stenzel-Poore, M., Stevens, S. L., Xiong, Z., Lessov, N. S., Harrington, C. C., Mori, M. T., Meller, R., Rosenzweig, H., Tobar, E., Shaw, T. E., Chu, X. & Simon, R. P., Sep 27 2003, In : Lancet. 362, 9389, p. 1028-1037 10 p.

Research output: Contribution to journalArticle

Hibernation
Ischemic Preconditioning
Brain Ischemia
Ischemia
Genes
40 Citations (Scopus)

Equilibrative nucleoside transporter family members from Leishmania donovani are electrogenic proton symporters

Stein, A., Vaseduvan, G., Carter, N., Ullman, B., Landfear, S. & Kavanaugh, M. P., Sep 12 2003, In : Journal of Biological Chemistry. 278, 37, p. 35127-35134 8 p.

Research output: Contribution to journalArticle

Nucleoside Transport Proteins
Symporters
Leishmania donovani
Protons
Pyrimidine Nucleosides
39 Citations (Scopus)

Herpes simplex virus gE/gI expressed in epithelial cells interferes with cell-to-cell spread

Collins, W. J. & Johnson, D., Feb 2003, In : Journal of Virology. 77, 4, p. 2686-2695 10 p.

Research output: Contribution to journalArticle

herpes simplex
Simplexvirus
epithelial cells
Epithelial Cells
viruses
72 Citations (Scopus)

Herpes simplex virus glycoproteins gD and gE/gI serve essential but redundant functions during acquisition of the virion envelope in the cytoplasm

Farnsworth, A., Goldsmith, K. & Johnson, D., Aug 2003, In : Journal of Virology. 77, 15, p. 8481-8494 14 p.

Research output: Contribution to journalArticle

herpes simplex
Simplexvirus
virion
Virion
glycoproteins
213 Citations (Scopus)

Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity

Dunn, C., Chalupny, N. J., Sutherland, C. L., Dosch, S., Sivakumar, P. V., Johnson, D. & Cosman, D., Jun 2 2003, In : Journal of Experimental Medicine. 197, 11, p. 1427-1439 13 p.

Research output: Contribution to journalArticle

Cytomegalovirus
Natural Killer Cells
Glycoproteins
Ligands
Major Histocompatibility Complex
27 Citations (Scopus)
Human herpesvirus 5
neuroglia
major histocompatibility complex
Major Histocompatibility Complex
Cytomegalovirus
22 Citations (Scopus)
Human herpesvirus 5
Histocompatibility
chimerism
protein degradation
Cytomegalovirus
32 Citations (Scopus)

Immunohistology of antigen-presenting cells in vivo: A novel method for serial observation of fluorescently labeled cells

Becker, M. D., Planck, S., Crespo, S., Garman, K., Fleischman, R. J., Dullforce, P., Seitz, G. W., Martin, T., Parker, D. & Rosenbaum, J. J., May 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 5, p. 2004-2009 6 p.

Research output: Contribution to journalArticle

Antigen-Presenting Cells
Observation
Ovalbumin
Dendritic Cells
Antibodies
24 Citations (Scopus)

Molecular and functional characterization of the first nucleobase transporter gene from African trypanosomes

Henriques, C., Sanchez, M., Tryon, R. & Landfear, S., Aug 31 2003, In : Molecular and Biochemical Parasitology. 130, 2, p. 101-110 10 p.

Research output: Contribution to journalArticle

Membrane Transport Proteins
Trypanosomiasis
Nucleoside Transport Proteins
Purine Nucleosides
Genes
43 Citations (Scopus)

Reduced attention in mice overproducing corticotropin-releasing hormone

Van Gaalen, M. M., Stenzel-Poore, M., Holsboer, F. & Steckler, T., Jun 16 2003, In : Behavioural Brain Research. 142, 1-2, p. 69-79 11 p.

Research output: Contribution to journalArticle

Corticotropin-Releasing Hormone
Depression
Diazepam
Transgenic Mice
Reaction Time
36 Citations (Scopus)

Reduced cerebral injury in CRH-R1 deficient mice after focal ischemia: A potential link to microglia and atrocytes that express CRH-R1

Stevens, S. L., Shaw, T. E., Dykhuizen, E., Lessov, N. S., Hill, J. K., Wurst, W. & Stenzel-Poore, M., Oct 1 2003, In : Journal of Cerebral Blood Flow and Metabolism. 23, 10, p. 1151-1159 9 p.

Research output: Contribution to journalArticle

Corticotropin-Releasing Hormone
Microglia
Ischemia
Wounds and Injuries
Corticotropin-Releasing Hormone Receptors
8 Citations (Scopus)

Repertoire shift in the humoral response to phosphocholine-keyhole limpet hemocyanin: VH somatic mutation in germinal center B cells impairs T15 Ig function

Wiens, G. D., Brown, M. & Rittenberg, M., May 15 2003, In : Journal of Immunology. 170, 10, p. 5095-5102 8 p.

Research output: Contribution to journalArticle

Germinal Center
Phosphorylcholine
B-Lymphocytes
Mutation
Clone Cells
6 Citations (Scopus)
Germ-Line Mutation
Light
Mutation
Antibodies
Amino Acids
64 Citations (Scopus)

Retrovirus capsid protein assembly arrangements

Mayo, K., Huseby, D., McDermott, J., Arvidson, B., Finlay, L. & Barklis, E., 2003, In : Journal of Molecular Biology. 325, 1, p. 225-237 13 p.

Research output: Contribution to journalArticle

Retroviridae Proteins
gag Gene Products
Capsid Proteins
Retroviridae
Morphogenesis
24 Citations (Scopus)

Spermine compaction is an efficient and economical method of producing vaccination-grade DNA

Mourich, D. V., Munks, M., Murphy, J. C., Willson, R. C. & Hill, A., Mar 1 2003, In : Journal of Immunological Methods. 274, 1-2, p. 257-264 8 p.

Research output: Contribution to journalArticle

Spermine
Vaccination
DNA
Endotoxins
Costs and Cost Analysis
48 Citations (Scopus)
adenosylhomocysteine nucleosidase
Catalysis
Escherichia coli
Substrates
Adenine
49 Citations (Scopus)

The Adenosine Analog Tubercidin Inhibits Glycolysis in Trypanosoma brucei as Revealed by an RNA Interference Library

Drew, M. E., Morris, J. C., Wang, Z., Wells, L., Sanchez, M., Landfear, S. & Englund, P. T., Nov 21 2003, In : Journal of Biological Chemistry. 278, 47, p. 46596-46600 5 p.

Research output: Contribution to journalArticle

Tubercidin
Trypanosoma brucei brucei
Glycolysis
RNA Interference
Adenosine