Research Output

Filter
Article
2009

Decreased outer membrane permeability protects mycobacteria from killing by ubiquitin-derived peptides

Purdy, G. E., Niederweis, M. & Russell, D. G., Sep 2009, In : Molecular Microbiology. 73, 5, p. 844-857 14 p.

Research output: Contribution to journalArticle

50 Scopus citations

Differential expression and molecular associations of Syk in systemic lupus erythematosus T cells

Krishnan, S., Juang, Y. T., Chowdhury, B., Magilavy, A., Fisher, C. U., Nguyen, H., Nambiar, M. P., Kyttaris, V., Weinstein, A., Bahjat, R., Pine, P., Rus, V. & Tsokos, G. C., Dec 1 2009, In : Journal of Immunology. 181, 11, p. 8145-8152 8 p.

Research output: Contribution to journalArticle

Open Access
77 Scopus citations

Discovery of dual function acridones as a new antimalarial chemotype

Kelly, J. X., Smilkstein, M. J., Brun, R., Wittlin, S., Cooper, R. A., Lane, K. D., Janowsky, A., Johnson, R. A., Dodean, R. A., Winter, R., Hinrichs, D. J. & Riscoe, M. K., May 14 2009, In : Nature. 459, 7244, p. 270-273 4 p.

Research output: Contribution to journalArticle

141 Scopus citations

Evidence that the modulatory effect of galanin on inflammatory edema formation is mediated by the galanin receptor 3 in the murine microvasculature

Schmidhuber, S. M., Rauch, I., Kofler, B. & Brain, S. D., Feb 1 2009, In : Journal of Molecular Neuroscience. 37, 2, p. 177-181 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Fusion between perinuclear virions and the outer nuclear membrane requires the fusogenic activity of herpes simplex virus gB

Wright, C. C., Wisner, T. W., Hannah, B. P., Eisenberg, R. J., Cohen, G. H. & Johnson, D. C., Nov 2009, In : Journal of virology. 83, 22, p. 11847-11856 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Herpesvirus gB-induced fusion between the virion envelope and outer nuclear membrane during virus egress is regulated by the viral US3 kinase

Wisner, T. W., Wright, C. C., Kato, A., Kawaguchi, Y., Mou, F., Baines, J. D., Roller, R. J. & Johnson, D. C., Apr 2009, In : Journal of virology. 83, 7, p. 3115-3126 12 p.

Research output: Contribution to journalArticle

76 Scopus citations

HIV-1 matrix organizes as a hexamer of trimers on membranes containing phosphatidylinositol-(4,5)-bisphosphate

Alfadhli, A., Barklis, R. L. & Barklis, E., May 10 2009, In : Virology. 387, 2, p. 466-472 7 p.

Research output: Contribution to journalArticle

71 Scopus citations

Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis

Blume, M., Rodriguez-Contreras, D., Landfear, S., Fleige, T., Soldati-Favre, D., Lucius, R. & Gupta, N., Aug 4 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 31, p. 12998-13003 6 p.

Research output: Contribution to journalArticle

60 Scopus citations

Inflammation and the emerging role of the toll-like receptor system in acute brain ischemia

Marsh, B. J., Stevens, S. L., Hunter, B. & Stenzel-Poore, M. P., Mar 2009, In : Stroke. 40, 3 SUPPL. 1, p. S34-S37

Research output: Contribution to journalArticle

37 Scopus citations

Investigation of the impact of the common animal facility contaminant murine norovirus on experimental murine cytomegalovirus infection

Doom, C. M., Turula, H. M. & Hill, A. B., Sep 30 2009, In : Virology. 392, 2, p. 153-161 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Iodothyronamines are oxidatively deaminated to iodothyroacetic acids in vivo

Wood, W. J. L., Geraci, T., Nilsen, A., DeBarber, A. E. & Scanlan, T. S., Jan 26 2009, In : ChemBioChem. 10, 2, p. 361-365 5 p.

Research output: Contribution to journalArticle

38 Scopus citations

Ly49P recognition of cytomegalovirus-infected cells expressing H2-D k and CMV-encoded m04 correlates with the NK cell antiviral response

Kielczewska, A., Pyzik, M., Sun, T., Krmpotic, A., Lodoen, M. B., Munks, M. W., Babic, M., Hill, A. B., Koszinowski, U. H., Jonjic, S., Lanier, L. L. & Vidal, S. M., Mar 16 2009, In : Journal of Experimental Medicine. 206, 3, p. 515-523 9 p.

Research output: Contribution to journalArticle

94 Scopus citations

Neural regulation of immunity: Role of NPR-1 in pathogen avoidance and regulation of innate immunity

Aballay, A., Apr 1 2009, In : Cell Cycle. 8, 7, p. 966-969 4 p.

Research output: Contribution to journalArticle

18 Scopus citations

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

Kamizono, S., Duncan, G. S., Seidel, M. G., Morimoto, A., Hamada, K., Grosveld, G., Akashi, K., Lind, E. F., Haight, J. P., Ohashi, P. S., Look, A. T. & Mak, T. W., Dec 21 2009, In : Journal of Experimental Medicine. 206, 13, p. 2977-2986 10 p.

Research output: Contribution to journalArticle

213 Scopus citations

Nucleolar proteins suppress Caenorhabditis elegans innate immunity by inhibiting p53/CEP-1

Fuhrman, L. E., Goel, A. K., Smith, J., Shianna, K. V. & Aballay, A., Sep 2009, In : PLoS genetics. 5, 9, e1000657.

Research output: Contribution to journalArticle

41 Scopus citations

Plasma adiponectin levels are increased despite insulin resistance in corticotropin-releasing hormone transgenic mice, an animal model of Cushing syndrome

Shinahara, M., Nishiyama, M., Iwasaki, Y., Nakayama, S., Noguchi, T., Kambayashi, M., Okada, Y., Tsuda, M., Stenzel-Poore, M. P., Hashimoto, K. & Terada, Y., Nov 9 2009, In : Endocrine Journal. 56, 7, p. 879-886 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Posttranslational regulation of the NKG2D ligand Multl in response to cell stress

Nice, T. J., Coscoy, L. & Raulet, D. H., Feb 16 2009, In : Journal of Experimental Medicine. 206, 2, p. 287-298 12 p.

Research output: Contribution to journalArticle

67 Scopus citations

Rapidly evolving adeno-associated virus vectors: Increasing possibility of gene therapy with custom-made vectors

Nakai, H., Dec 1 2009, In : Drug Delivery System. 24, 6, p. 582-591 10 p.

Research output: Contribution to journalArticle

Regulation of DAF-16-mediated innate immunity in Caenorhabditis elegans

Singh, V. & Aballay, A., Dec 18 2009, In : Journal of Biological Chemistry. 284, 51, p. 35580-35587 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Severe dengue epidemics in Sri Lanka, 2003-2006

Kanakaratne, N., Wahala, W. M. P. B., Messer, W. B., Tissera, H. A., Shahani, A., Abeysinghe, N., De Silva, A. M. & Gunasekera, M., Feb 2009, In : Emerging infectious diseases. 15, 2, p. 192-199 8 p.

Research output: Contribution to journalArticle

92 Scopus citations

Silicate Nephrolithiasis After Ingestion of Supplements Containing Silica Dioxide

Flythe, J. E., Rueda, J. F., Riscoe, M. K. & Watnick, S., Jul 1 2009, In : American Journal of Kidney Diseases. 54, 1, p. 127-130 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER

Vacaru, A. M., Tafesse, F. G., Ternes, P., Kondylis, V., Hermansson, M., Brouwers, J. F. H. M., Somerharju, P., Rabouille, C. & Holthuis, J. C. M., Jun 15 2009, In : Journal of Cell Biology. 185, 6, p. 1013-1027 15 p.

Research output: Contribution to journalArticle

103 Scopus citations

Systemic lipopolysaccharide protects the brain from ischemic injury by reprogramming the response of the brain to stroke: A critical role for IRF3

Marsh, B., Stevens, S. L., Packard, A. E. B., Gopalan, B., Hunter, B., Leung, P. Y., Harrington, C. A. & Stenzel-Poore, M. P., Aug 5 2009, In : Journal of Neuroscience. 29, 31, p. 9839-9849 11 p.

Research output: Contribution to journalArticle

149 Scopus citations

Two novel nucleobase/pentamidine transporters from Trypanosoma brucei

Ortiz, D., Sanchez, M. A., Quecke, P. & Landfear, S. M., Feb 2009, In : Molecular and Biochemical Parasitology. 163, 2, p. 67-76 10 p.

Research output: Contribution to journalArticle

21 Scopus citations
2008

A conserved Toll-like receptor is required for Caenorhabditis elegans innate immunity

Tenor, J. L. & Aballay, A., Jan 2008, In : EMBO Reports. 9, 1, p. 103-109 7 p.

Research output: Contribution to journalArticle

116 Scopus citations

A drug-selected Plasmodium falciparum lacking the need for conventional electron transport

Smilkstein, M. J., Forquer, I., Kanazawa, A., Kelly, J. X., Winter, R. W., Hinrichs, D. J., Kramer, D. M. & Riscoe, M. K., May 2008, In : Molecular and Biochemical Parasitology. 159, 1, p. 64-68 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Analysis of human immunodeficiency virus matrix domain replacements

Scholz, I., Still, A., Dhenub, T. C., Coday, K., Webb, M. & Barklis, E., Feb 20 2008, In : Virology. 371, 2, p. 322-335 14 p.

Research output: Contribution to journalArticle

19 Scopus citations

An expression system to screen for inhibitors of parasite glucose transporters

Feistel, T., Hodson, C. A., Peyton, D. H. & Landfear, S. M., Nov 2008, In : Molecular and Biochemical Parasitology. 162, 1, p. 71-76 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupus

Bahjat, F. R., Pine, P. R., Reitsma, A., Cassafer, G., Baluom, M., Grillo, S., Chang, B., Fei, F. Z., Payan, D. G., Grossbard, E. B. & Daikh, D. I., May 1 2008, In : Arthritis and rheumatism. 58, 5, p. 1433-1444 12 p.

Research output: Contribution to journalArticle

133 Scopus citations

Antimalarial quinolones: Synthesis, potency, and mechanistic studies

Winter, R. W., Kelly, J. X., Smilkstein, M. J., Dodean, R., Hinrichs, D. & Riscoe, M. K., Apr 2008, In : Experimental Parasitology. 118, 4, p. 487-497 11 p.

Research output: Contribution to journalArticle

112 Scopus citations

Cellular FLIP can substitute for the herpes simplex virus type 1 latency-associated transcript gene to support a wild-type virus reactivation phenotype in mice

Jin, L., Carpenter, D., Moerdyk-Schauwecker, M., Vanarsdall, A. L., Osorio, N., Hsiang, C., Jones, C. & Wechsler, S. L., 2008, In : Journal of neurovirology. 14, 5, p. 389-400 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

Characterization of a novel alphaherpesvirus associated with fatal infections of domestic rabbits

Jin, L., Löhr, C. V., Vanarsdall, A. L., Baker, R. J., Moerdyk-Schauwecker, M., Levine, C., Gerlach, R. F., Cohen, S. A., Alvarado, D. E. & Rohrmann, G. F., Aug 15 2008, In : Virology. 378, 1, p. 13-20 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Characterization of the human cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and endothelial cells

Ryckman, B. J., Rainish, B. L., Chase, M. C., Borton, J. A., Nelson, J. A., Jarvis, M. A. & Johnson, D. C., Jan 2008, In : Journal of virology. 82, 1, p. 60-70 11 p.

Research output: Contribution to journalArticle

216 Scopus citations

Corticotropin-releasing factor-1 receptor involvement in behavioral neuroadaptation to ethanol: A urocortin1-independent mechanism

Pastor, R., McKinnon, C. S., Scibelli, A. C., Burkhart-Kasch, S., Reed, C., Ryabinin, A. E., Coste, S. C., Stenzel-Poore, M. P. & Phillips, T. J., Jul 1 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 26, p. 9070-9075 6 p.

Research output: Contribution to journalArticle

53 Scopus citations

Dendritic cells require the NF-κB2 pathway for cross-presentation of soluble antigens

Lind, E. F., Ahonen, C. L., Wasiuk, A., Kosaka, Y., Becher, B., Bennett, K. A. & Noelle, R. J., 2008, In : Journal of Immunology. 181, 1, p. 354-363 10 p.

Research output: Contribution to journalArticle

Open Access
43 Scopus citations

Efficient and Durable Gene Transfer to Transplanted Heart Using Adeno-associated Virus 9 Vector

Miyagi, N., Rao, V. P., Ricci, D., Du, Z., Byrne, G. W., Bailey, K. R., Nakai, H., Russell, S. J. & McGregor, C. G. A., May 2008, In : Journal of Heart and Lung Transplantation. 27, 5, p. 554-560 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Frequency and spectrum of genomic integration of recombinant adeno-associated virus serotype 8 vector in neonatal mouse liver

Inagaki, K., Piao, C., Kotchey, N. M., Wu, X. & Nakai, H., Oct 2008, In : Journal of virology. 82, 19, p. 9513-9524 12 p.

Research output: Contribution to journalArticle

34 Scopus citations
131 Scopus citations

Herpes simplex virus gE/gI and US9 proteins promote transport of both capsids and virion glycoproteins in neuronal axons

Snyder, A., Polcicova, K. & Johnson, D. C., Nov 2008, In : Journal of virology. 82, 21, p. 10613-10624 12 p.

Research output: Contribution to journalArticle

64 Scopus citations

High-throughput isolation and mapping of C. elegans mutants susceptible to pathogen infection

Fuhrman, L. E., Shianna, K. V. & Aballay, A., Aug 6 2008, In : PloS one. 3, 8, e2882.

Research output: Contribution to journalArticle

7 Scopus citations

Human cytomegalovirus glycoproteins gB and gH/gL mediate epithelial cell-cell fusion when expressed either in cis or in trans

Vanarsdall, A. L., Ryckman, B. J., Chase, M. C. & Johnson, D. C., Dec 2008, In : Journal of virology. 82, 23, p. 11837-11850 14 p.

Research output: Contribution to journalArticle

102 Scopus citations

Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR

Styer, K. L., Singh, V., Macosko, E., Steele, S. E., Bargmann, C. I. & Aballay, A., Oct 17 2008, In : Science. 322, 5900, p. 460-464 5 p.

Research output: Contribution to journalArticle

134 Scopus citations

Isolation and characterization of the DNA-binding protein (DBP) of the Autographa californica multiple nucleopolyhedrovirus

Mikhailov, V. S., Vanarsdall, A. L. & Rohrmann, G. F., Jan 20 2008, In : Virology. 370, 2, p. 415-429 15 p.

Research output: Contribution to journalArticle

15 Scopus citations

Mechanisms of ischemic brain damage

Doyle, K. P., Simon, R. P. & Stenzel-Poore, M. P., Sep 2008, In : Neuropharmacology. 55, 3, p. 310-318 9 p.

Research output: Contribution to journalArticle

548 Scopus citations

Memory Inflation during Chronic Viral Infection Is Maintained by Continuous Production of Short-Lived, Functional T Cells

Snyder, C. M., Cho, K. S., Bonnett, E. L., van Dommelen, S., Shellam, G. R. & Hill, A. B., Oct 17 2008, In : Immunity. 29, 4, p. 650-659 10 p.

Research output: Contribution to journalArticle

204 Scopus citations

MMP-9 haplotypes and carotid artery atherosclerosis: An association study introducing a novel multicolour multiplex RealTime PCR protocol

Rauch, I., Iglseder, B., Paulweber, B., Ladurner, G. & Strasser, P., Jan 2008, In : European Journal of Clinical Investigation. 38, 1, p. 24-33 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Nasal administration of osteopontin peptide mimetics confers neuroprotection in stroke

Doyle, K. P., Yang, T., Lessov, N. S., Ciesielski, T. M., Stevens, S. L., Simon, R. P., King, J. S. & Stenzel-Poore, M. P., Jun 30 2008, In : Journal of Cerebral Blood Flow and Metabolism. 28, 6, p. 1235-1248 14 p.

Research output: Contribution to journalArticle

69 Scopus citations

Recombinant adeno-associated virus type 8-mediated extensive therapeutic gene delivery into skeletal muscle of α-sarcoglycan-deficient mice

Nishiyama, A., Ampong, B. N., Ohshima, S., Shin, J. H., Nakai, H., Imamura, M., Miyagoe-Suzuki, Y., Okada, T. & Takeda, S., Jul 1 2008, In : Human Gene Therapy. 19, 7, p. 719-730 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Resistance of Yersinia pestis to complement-dependent killing is mediated by the ail outer membrane protein

Bartra, S. S., Styer, K. L., O'Bryant, D. M., Nilles, M. L., Hinnebusch, B. J., Aballay, A. & Plano, G. V., Feb 2008, In : Infection and Immunity. 76, 2, p. 612-622 11 p.

Research output: Contribution to journalArticle

99 Scopus citations

Semi-field evaluation of a granulovirus and Bacillus thuringiensis ssp. kurstaki for season-long control of the potato tuber moth, Phthorimaea operculella

Arthurs, S. P., Lacey, L. A., Pruneda, J. N. & Rondon, S. I., Dec 1 2008, In : Entomologia Experimentalis et Applicata. 129, 3, p. 276-285 10 p.

Research output: Contribution to journalArticle

16 Scopus citations