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2012

Poly-IC preconditioning protects against cerebral and renal ischemia-reperfusion injury

Packard, A. E. B., Hedges, J. C., Bahjat, F. R., Stevens, S. L., Conlin, M. J., Salazar, A. M. & Stenzel-Poore, M. P., Feb 1 2012, In : Journal of Cerebral Blood Flow and Metabolism. 32, 2, p. 242-247 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

Preformed CD40L is stored in Th1, Th2, Th17, and T follicular helper cells as well as CD4 +8 - thymocytes and invariant NKT cells but not in Treg cells

Koguchi, Y., Buenafe, A. C., Thauland, T. J., Gardell, J. L., Bivins-Smith, E. R., Jacoby, D. B., Slifka, M. K. & Parker, D. C., Feb 21 2012, In : PloS one. 7, 2, e31296.

Research output: Contribution to journalArticle

26 Scopus citations
19 Scopus citations

Sontochin as a guide to the development of drugs against chloroquine-resistant malaria

Pou, S., Winter, R. W., Nilsen, A., Kelly, J. X., Li, Y., Doggett, J. S., Riscoe, E. W., Wegmann, K. W., Hinrichs, D. J. & Riscoe, M. K., Jul 1 2012, In : Antimicrobial agents and chemotherapy. 56, 7, p. 3475-3480 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Structural and functional characterization of mycobactericidal ubiquitin-derived peptides in model and bacterial membranes

Foss, M. H., Powers, K. M. & Purdy, G. E., Dec 11 2012, In : Biochemistry. 51, 49, p. 9922-9929 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
7 Scopus citations

Structural insights into the conformation and oligomerization of e2∼ubiquitin conjugates

Page, R. C., Pruneda, J. N., Amick, J., Klevit, R. E. & Misra, S., May 22 2012, In : Biochemistry. 51, 20, p. 4175-4187 13 p.

Research output: Contribution to journalArticle

44 Scopus citations

Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases

Pruneda, J. N., Littlefield, P. J., Soss, S. E., Nordquist, K. A., Chazin, W. J., Brzovic, P. S. & Klevit, R. E., Sep 28 2012, In : Molecular Cell. 47, 6, p. 933-942 10 p.

Research output: Contribution to journalArticle

Open Access
177 Scopus citations

Sultam thioureas: Synthesis and antiviral activity against west nile virus

Feeny, R. M., Le, D. N., Parks, J. W., Epstein, M. G., Pagano, J. V., Abbene, A. C., Graham, E. B., Farrell, J. R., McGuire, J. R., Zoellner, R. W., Valente, E. J., Barklis, E. & Wood, W. J. L., Jan 1 2012, In : Synlett. 2, p. 301-305 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk

Arpaia, E., Blaser, H., Quintela-Fandino, M., Duncan, G., Leong, H. S., Ablack, A., Nambiar, S. C., Lind, E. F., Silvester, J., Fleming, C. K., Rufini, A., Tusche, M. W., Brüstle, A., Ohashi, P. S., Lewis, J. D. & Mak, T. W., Feb 16 2012, In : Oncogene. 31, 7, p. 884-896 13 p.

Research output: Contribution to journalArticle

79 Scopus citations

TLR9 bone marrow chimeric mice define a role for cerebral TNF in neuroprotection induced by CpG preconditioning

Packard, A. E. B., Leung, P. Y., Vartanian, K. B., Stevens, S. L., Bahjat, F. R. & Stenzel-Poore, M. P., Dec 1 2012, In : Journal of Cerebral Blood Flow and Metabolism. 32, 12, p. 2193-2200 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Toll-like receptor 7 preconditioning induces robust neuroprotection against stroke by a novel type i interferon-mediated mechanism

Leung, P. Y., Stevens, S. L., Packard, A. E. B., Lessov, N. S., Yang, T., Conrad, V. K., Van Den Dungen, N. N. A. M., Simon, R. P. & Stenzel-Poore, M. P., May 1 2012, In : Stroke. 43, 5, p. 1383-1389 7 p.

Research output: Contribution to journalArticle

49 Scopus citations
2011

A constitutive pan-hexose permease for the Plasmodium life cycle and transgenic models for screening of antimalarial sugar analogs

Blume, M., Hliscs, M., Rodriguez-Contreras, D., Sanchez, M., Landfear, S., Lucius, R., Matuschewski, K. & Gupta, N., Apr 1 2011, In : FASEB Journal. 25, 4, p. 1218-1229 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Analysis of the N-terminal region of the murine leukemia virus nucleocapsid protein

Still, A., Huseby, D. & Barklis, E., Jan 1 2011, In : Virus Research. 155, 1, p. 181-188 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Anterograde transport of herpes simplex virus capsids in neurons by both separate and married mechanisms

Wisner, T. W., Sugimoto, K., Howard, P. W., Kawaguchi, Y. & Johnson, D. C., Jun 2011, In : Journal of virology. 85, 12, p. 5919-5928 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

A potential role of distinctively delayed blood clearance of recombinant adeno-associated virus serotype 9 in robust cardiac transduction

Kotchey, N. M., Adachi, K., Zahid, M., Inagaki, K., Charan, R., Parker, R. S. & Nakai, H., Jun 2011, In : Molecular Therapy. 19, 6, p. 1079-1089 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

Comparing the kinetics of NK cells, CD4, and CD8 T cells in murine cytomegalovirus infection

Schlub, T. E., Sun, J. C., Walton, S. M., Robbins, S. H., Pinto, A. K., Munks, M. W., Hill, A. B., Brossay, L., Oxenius, A. & Davenport, M. P., Aug 1 2011, In : Journal of Immunology. 187, 3, p. 1385-1392 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Corticotropin-releasing hormone (CRH) transgenic mice display hyperphagia with increased Agouti-related protein mRNA in the hypothalamic arcuate nucleus

Nakayama, S., Nishiyama, M., Iwasaki, Y., Shinahara, M., Okada, Y., Tsuda, M., Okazaki, M., Tsugita, M., Taguchi, T., Makino, S., Poore, M. P. S., Hashimoto, K. & Terada, Y., May 13 2011, In : Endocrine Journal. 58, 4, p. 279-286 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

CRF receptor antagonist astressin-B reverses and prevents alopecia in CRF over-expressing mice

Wang, L., Million, M., Rivier, J., Rivier, C., Craft, N., Stenzel-Poore, M. P. & Taché, Y., 2011, In : PloS one. 6, 2, e16377.

Research output: Contribution to journalArticle

23 Scopus citations

Cyclosporine-resistant, Rab27a-independent mobilization of intracellular preformed CD40 ligand mediates antigen-specific T cell help in vitro

Koguchi, Y., Gardell, J. L., Thauland, T. J. & Parker, D. C., Jul 15 2011, In : Journal of Immunology. 187, 2, p. 626-634 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Determinants of the HIV-1 core assembly pathway

López, C. S., Eccles, J. D., Still, A., Sloan, R. E., Barklis, R. L., Tsagli, S. M. & Barklis, E., Aug 15 2011, In : Virology. 417, 1, p. 137-146 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Direct injection into the dorsal root ganglion: Technical, behavioral, and histological observations

Fischer, G., Kostic, S., Nakai, H., Park, F., Sapunar, D., Yu, H. & Hogan, Q., Jul 15 2011, In : Journal of Neuroscience Methods. 199, 1, p. 43-55 13 p.

Research output: Contribution to journalArticle

43 Scopus citations

Dissection of corticotropin-releasing factor system involvement in locomotor sensitivity to methamphetamine

Giardino, W. J., Pastor, R., Anacker, A. M. J., Spangler, E., Cote, D. M., Li, J., Stenzel-Poore, M. P., Phillips, T. J. & Ryabinin, A. E., Feb 1 2011, In : Genes, Brain and Behavior. 10, 1, p. 78-89 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Effects of galanin message-associated peptide and neuropeptide y against various non-albicans Candida strains

Holub, B. S., Rauch, I., Radner, S., Sperl, W., Hell, M. & Kofler, B., Jul 1 2011, In : International Journal of Antimicrobial Agents. 38, 1, p. 76-80 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Ethanol concentration-dependent effects and the role of stress on ethanol drinking in corticotropin-releasing factor type 1 and double type 1 and 2 receptor knockout mice

Pastor, R., Reed, C., Burkhart-Kasch, S., Li, N., Sharpe, A. L., Coste, S. C., Stenzel-Poore, M. P. & Phillips, T. J., Nov 1 2011, In : Psychopharmacology. 218, 1, p. 169-177 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Herpes simplex virus glycoproteins gB and gD function in a redundant fashion to promote secondary envelopment

Johnson, D. C., Wisner, T. W. & Wright, C. C., May 1 2011, In : Journal of virology. 85, 10, p. 4910-4926 17 p.

Research output: Contribution to journalArticle

21 Scopus citations

Herpesviruses remodel host membranes for virus egress

Johnson, D. C. & Baines, J. D., May 1 2011, In : Nature Reviews Microbiology. 9, 5, p. 382-394 13 p.

Research output: Contribution to journalArticle

277 Scopus citations

HIV-1 matrix protein binding to RNA

Alfadhli, A., McNett, H., Tsagli, S., Bächinger, H. P., Peyton, D. H. & Barklis, E., Jul 22 2011, In : Journal of molecular biology. 410, 4, p. 653-666 14 p.

Research output: Contribution to journalArticle

52 Scopus citations
58 Scopus citations

In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection

de Alwis, R., Beltramello, M., Messer, W. B., Sukupolvi-Petty, S., Wahala, W. M. P. B., Kraus, A., Olivarez, N. P., Pham, Q., Brian, J., Tsai, W. Y., Wang, W. K., Halstead, S., Kliks, S., Diamond, M. S., Baric, R., Lanzavecchia, A., Sallusto, F. & de Silva, A. M., Jun 2011, In : PLoS neglected tropical diseases. 5, 6, e1188.

Research output: Contribution to journalArticle

146 Scopus citations

Low-pH-dependent changes in the conformation and oligomeric state of the prefusion form of herpes simplex virus glycoprotein B are separable from fusion activity

Dollery, S. J., Wright, C. C., Johnson, D. C. & Nicola, A. V., Oct 1 2011, In : Journal of virology. 85, 19, p. 9964-9973 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury

Vartanian, K. B., Stevens, S. L., Marsh, B. J., Williams-Karnesky, R., Lessov, N. S. & Stenzel-Poore, M. P., Oct 14 2011, In : Journal of Neuroinflammation. 8, 140.

Research output: Contribution to journalArticle

94 Scopus citations

Lysosomal degradation of Leishmania hexose and inositol transporters is regulated in a stage-, nutrient- and ubiquitin-dependent manner

Vince, J. E., Tull, D., Landfear, S. & McConville, M. J., Jun 1 2011, In : International Journal for Parasitology. 41, 7, p. 791-800 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Minireview: Computational prediction of type III and IV secreted effectors in gram-negative bacteria

McDermott, J. E., Corrigan, A., Peterson, E., Oehmen, C., Niemann, G., Cambronne, E. D., Sharp, D., Adkins, J. N., Samudrala, R. & Heffron, F., Jan 2011, In : Infection and Immunity. 79, 1, p. 23-32 10 p.

Research output: Contribution to journalArticle

72 Scopus citations

Models to study ancient host-pathogen interactions: Lessons from Crete

Means, T. K. & Aballay, A., Jan 1 2011, In : EMBO Reports. 12, 1, p. 5-7 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Multiple preconditioning paradigms converge on interferon regulatory factor-dependent signaling to promote tolerance to ischemic brain injury

Stevens, S. L., Leung, P. Y., Vartanian, K. B., Gopalan, B., Yang, T., Simon, R. P. & Stenzel-Poore, M. P., Jun 8 2011, In : Journal of Neuroscience. 31, 23, p. 8456-8463 8 p.

Research output: Contribution to journalArticle

89 Scopus citations

Mycobacterium smegmatis RoxY is a repressor of oxyS and contributes to resistance to oxidative stress and bactericidal ubiquitin-derived peptides

Daugherty, A., Powers, K. M., Standley, M. S., Kim, C. S. & Purdy, G. E., Dec 1 2011, In : Journal of bacteriology. 193, 24, p. 6824-6833 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Neuronal GPCR controls innate immunity by regulating noncanonical unfolded protein response genes

Sun, J., Singh, V., Kajino-Sakamoto, R. & Aballay, A., May 6 2011, In : Science. 332, 6030, p. 729-732 4 p.

Research output: Contribution to journalArticle

127 Scopus citations

NF-κB-inducing kinase plays an essential T cell-intrinsic role in graft-versus-host disease and lethal autoimmunity in mice

Murray, S. E., Polesso, F., Rowe, A. M., Basak, S., Koguchi, Y., Toren, K. G., Hoffmann, A. & Parker, D. C., Dec 1 2011, In : Journal of Clinical Investigation. 121, 12, p. 4775-4786 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Nutrient transport and pathogenesis in selected parasitic protozoa

Landfear, S. M., Apr 1 2011, In : Eukaryotic Cell. 10, 4, p. 483-493 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

Optimization of endochin-like quinolones for antimalarial activity

Winter, R., Kelly, J. X., Smilkstein, M. J., Hinrichs, D., Koop, D. R. & Riscoe, M. K., Feb 1 2011, In : Experimental Parasitology. 127, 2, p. 545-551 7 p.

Research output: Contribution to journalArticle

50 Scopus citations

Peptides from cytomegalovirus UL130 and UL131 proteins induce high titer antibodies that block viral entry into mucosal epithelial cells

Saccoccio, F. M., Sauer, A. L., Cui, X., Armstrong, A. E., Habib, EL. S. E., Johnson, D. C., Ryckman, B. J., Klingelhutz, A. J., Adler, S. P. & McVoy, M. A., Mar 24 2011, In : Vaccine. 29, 15, p. 2705-2711 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Proof of concept: Pharmacological preconditioning with a Toll-like receptor agonist protects against cerebrovascular injury in a primate model of stroke

Bahjat, F. R., Williams-Karnesky, R. L., Kohama, S. G., West, G. A., Doyle, K. P., Spector, M. D., Hobbs, T. R. & Stenzel-Poore, M. P., May 1 2011, In : Journal of Cerebral Blood Flow and Metabolism. 31, 5, p. 1229-1242 14 p.

Research output: Contribution to journalArticle

39 Scopus citations

Protective Capacity of Memory CD8+ T Cells Is Dictated by Antigen Exposure History and Nature of the Infection

Nolz, J. C. & Harty, J. T., May 27 2011, In : Immunity. 34, 5, p. 781-793 13 p.

Research output: Contribution to journalArticle

68 Scopus citations

Reductions in claudin-1 may enhance susceptibility to herpes simplex virus 1 infections in atopic dermatitis

De Benedetto, A., Slifka, M. K., Rafaels, N. M., Kuo, I. H., Georas, S. N., Boguniewicz, M., Hata, T., Schneider, L. C., Hanifin, J. M., Gallo, R. L., Johnson, D. C., Barnes, K. C., Leung, D. Y. M. & Beck, L. A., Jul 2011, In : Journal of Allergy and Clinical Immunology. 128, 1, p. 242-246.e5

Research output: Contribution to journalArticle

59 Scopus citations

Remodeling of protein and mRNA expression in Leishmania mexicana induced by deletion of glucose transporter genes

Feng, X., Feistel, T., Buffalo, C., McCormack, A., Kruvand, E., Rodriguez-Contreras, D., Akopyants, N. S., Umasankar, P. K., David, L., Jardim, A., Beverley, S. M. & Landfear, S. M., Jan 1 2011, In : Molecular and Biochemical Parasitology. 175, 1, p. 39-48 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Second-site compensatory mutations of HIV-1 capsid mutations

Noviello, C. M., López, C. S., Kukull, B., McNett, H., Still, A., Eccles, J., Sloan, R. & Barklis, E., May 2011, In : Journal of virology. 85, 10, p. 4730-4738 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Structural and functional studies on the interaction of gspc and gspd in the type ii secretion system

Korotkov, K. V., Johnson, T. L., Jobling, M. G., Pruneda, J., Pardon, E., Héroux, A., Turley, S., Steyaert, J., Holmes, R. K., Sandkvist, M. & Hol, W. G. J., Sep 2011, In : PLoS pathogens. 7, 9, e1002228.

Research output: Contribution to journalArticle

Open Access
59 Scopus citations

Sustained CD8+ T cell memory inflation after infection with a single-cycle Cytomegalovirus

Snyder, C. M., Cho, K. S., Bonnett, E. L., Allan, J. E. & Hill, A. B., Oct 1 2011, In : PLoS pathogens. 7, 10, e1002295.

Research output: Contribution to journalArticle

73 Scopus citations
6 Scopus citations