Research Output 1969 2019

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2009
38 Citations (Scopus)

Adenovirus vectors expressing hantavirus proteins protect hamsters against lethal challenge with Andes virus

Safronetz, D., Hegde, N. R., Ebihara, H., Denton, M., Kobinger, G. P., St. Jeor, S., Feldmann, H. & Johnson, D., Jul 2009, In : Journal of Virology. 83, 14, p. 7285-7295 11 p.

Research output: Contribution to journalArticle

Hantavirus
Adenoviridae
lethal genes
hamsters
Cricetinae
17 Citations (Scopus)

Amplification of an alternate transporter gene suppresses the avirulent phenotype of glucose transporter null mutants in Leishmania mexicana

Feng, X., Rodriguez-Contreras, D., Buffalo, C., Bouwer, H. G. A., Kruvand, E., Beverley, S. M. & Landfear, S., Jan 2009, In : Molecular Microbiology. 71, 2, p. 369-381 13 p.

Research output: Contribution to journalArticle

Leishmania mexicana
Facilitative Glucose Transport Proteins
Monosaccharide Transport Proteins
Phenotype
Membrane Transport Proteins
20 Citations (Scopus)

An ab initio structural model of a nucleoside permease predicts functionally important residues

Valdés, R., Arastu-Kapur, S., Landfear, S. & Shinde, U., Jul 10 2009, In : Journal of Biological Chemistry. 284, 28, p. 19067-19076 10 p.

Research output: Contribution to journalArticle

Membrane Transport Proteins
Structural Models
Nucleosides
Substrate Specificity
Mutation
22 Citations (Scopus)

An acid-activated nucleobase transporter from Leishmania major

Ortiz, D., Sanchez, M., Koch, H. P., Larson, H. P. & Landfear, S., Jun 12 2009, In : Journal of Biological Chemistry. 284, 24, p. 16164-16169 6 p.

Research output: Contribution to journalArticle

Leishmania major
Macrophages
Adenine
Acids
Protozoa
94 Citations (Scopus)

Analysis of human immunodeficiency virus type 1 matrix binding to membranes and nucleic acids

Alfadhli, A., Still, A. & Barklis, E., Dec 2009, In : Journal of Virology. 83, 23, p. 12196-12203 8 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus 1
Nucleic Acids
nucleic acids
HIV-1
Liposomes
39 Citations (Scopus)

A new model of cortical stroke in the rhesus macaque

West, G. A., Golshani, K. J., Doyle, K. P., Lessov, N. S., Hobbs, T., Kohama, S., Pike, M., Kroenke, C. C., Grafe, M., Spector, M. D., Tobar, E. T., Simon, R. P. & Stenzel-Poore, M., Jun 2009, In : Journal of Cerebral Blood Flow and Metabolism. 29, 6, p. 1175-1186 12 p.

Research output: Contribution to journalArticle

Macaca mulatta
Anterior Cerebral Artery
Ischemia
Stroke
Neurologic Manifestations
51 Citations (Scopus)

Arsenic transport by zebrafish aquaglyceroporins

Hamdi, M., Sanchez, M., Beene, L. C., Liu, Q., Landfear, S., Rosen, B. P. & Liu, Z., Nov 25 2009, In : BMC Molecular Biology. 10, 104.

Research output: Contribution to journalArticle

Aquaglyceroporins
Arsenic
Zebrafish
Aptitude
Fishes
53 Citations (Scopus)

CD4+ T cell help has an epitope-dependent impact on CD8 + T cell memory inflation during murine cytomegalovirus infection

Snyder, C. M., Loewendorf, A., Bonnett, E. L., Croft, M., Benedict, C. A. & Hill, A., Sep 15 2009, In : Journal of Immunology. 183, 6, p. 3932-3941 10 p.

Research output: Contribution to journalArticle

Muromegalovirus
Economic Inflation
Cytomegalovirus Infections
Epitopes
T-Lymphocytes
37 Citations (Scopus)

Characterization of the In Vitro HIV-1 Capsid Assembly Pathway

Barklis, E., Alfadhli, A., McQuaw, C., Yalamuri, S., Still, A., Barklis, R. L., Kukull, B. & Lopez, C., Mar 27 2009, In : Journal of Molecular Biology. 387, 2, p. 376-389 14 p.

Research output: Contribution to journalArticle

Capsid
HIV-1
Capsid Proteins
Antiviral Agents
Virus Uncoating
23 Citations (Scopus)

Corticotropin-releasing factor-overexpressing mice exhibit reduced neuronal activation in the arcuate nucleus and food intake in response to fasting

Stengel, A., Goebel, M., Million, M., Stenzel-Poore, M., Kobelt, P., Mönnikes, H., Taché, Y. & Wang, L., Jan 2009, In : Endocrinology. 150, 1, p. 153-160 8 p.

Research output: Contribution to journalArticle

Arcuate Nucleus of Hypothalamus
Corticotropin-Releasing Hormone
Fasting
Eating
Ghrelin
42 Citations (Scopus)

CRF 1 and CRF 2 receptors are required for potentiated startle to contextual but not discrete cues

Risbrough, V. B., Geyer, M. A., Hauger, R. L., Coste, S., Stenzel-Poore, M., Wurst, W. & Holsboer, F., May 2009, In : Neuropsychopharmacology. 34, 6, p. 1494-1503 10 p.

Research output: Contribution to journalArticle

Corticotropin-Releasing Hormone
Cues
Fear
Knockout Mice
CRF receptor type 2
42 Citations (Scopus)

CRF enhancement of GIRK channel-mediated transmission in dopamine neurons

Beckstead, M. J., Gantz, S. C., Ford, C. P., Stenzel-Poore, M., Phillips, P. E. M., Mark, G. & Williams, J., Jul 2009, In : Neuropsychopharmacology. 34, 8, p. 1926-1935 10 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Corticotropin-Releasing Hormone
Dopamine
Inhibitory Postsynaptic Potentials
Mesencephalon
49 Citations (Scopus)

Decreased outer membrane permeability protects mycobacteria from killing by ubiquitin-derived peptides

Purdy, G., Niederweis, M. & Russell, D. G., Sep 2009, In : Molecular Microbiology. 73, 5, p. 844-857 14 p.

Research output: Contribution to journalArticle

Mycobacterium smegmatis
Mycobacterium
Ubiquitin
Permeability
Peptides
135 Citations (Scopus)

Discovery of dual function acridones as a new antimalarial chemotype

Kelly, J. X., Smilkstein, M. J., Brun, R., Wittlin, S., Cooper, R. A., Lane, K. D., Janowsky, A., Johnson, R. A., Dodean, R. A., Winter, R., Hinrichs, D. J. & Riscoe, M., May 14 2009, In : Nature. 459, 7244, p. 270-273 4 p.

Research output: Contribution to journalArticle

Acridones
Antimalarials
Parasites
Heme
Pharmaceutical Preparations
24 Citations (Scopus)

Fusion between perinuclear virions and the outer nuclear membrane requires the fusogenic activity of herpes simplex virus gB

Wright, C. C., Wisner, T. W., Hannah, B. P., Eisenberg, R. J., Cohen, G. H. & Johnson, D., Nov 2009, In : Journal of Virology. 83, 22, p. 11847-11856 10 p.

Research output: Contribution to journalArticle

herpes simplex
Nuclear Envelope
nuclear membrane
Simplexvirus
virion
72 Citations (Scopus)

Herpesvirus gB-induced fusion between the virion envelope and outer nuclear membrane during virus egress is regulated by the viral US3 kinase

Wisner, T. W., Wright, C. C., Kato, A., Kawaguchi, Y., Mou, F., Baines, J. D., Roller, R. J. & Johnson, D., Apr 2009, In : Journal of Virology. 83, 7, p. 3115-3126 12 p.

Research output: Contribution to journalArticle

Virus Release
Herpesviridae
herpes simplex
Nuclear Envelope
nuclear membrane
65 Citations (Scopus)

HIV-1 matrix organizes as a hexamer of trimers on membranes containing phosphatidylinositol-(4,5)-bisphosphate

Alfadhli, A., Barklis, R. L. & Barklis, E., May 10 2009, In : Virology. 387, 2, p. 466-472 7 p.

Research output: Contribution to journalArticle

gag Gene Products
Phosphatidylinositols
Myristic Acid
HIV-1
Membranes
53 Citations (Scopus)

Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis

Blume, M., Rodriguez-Contreras, D., Landfear, S., Fleige, T., Soldati-Favre, D., Lucius, R. & Gupta, N., Aug 4 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 31, p. 12998-13003 6 p.

Research output: Contribution to journalArticle

Facilitative Glucose Transport Proteins
Toxoplasma
Glutamine
Glucose
Growth
35 Citations (Scopus)

Inflammation and the emerging role of the toll-like receptor system in acute brain ischemia

Marsh, B. J., Stevens, S. L., Hunter, B. & Stenzel-Poore, M., Mar 2009, In : Stroke. 40, 3 SUPPL. 1

Research output: Contribution to journalArticle

Transcriptional Regulatory Elements
Toll-Like Receptors
Brain Ischemia
Leukocytes
Inflammation
16 Citations (Scopus)

Investigation of the impact of the common animal facility contaminant murine norovirus on experimental murine cytomegalovirus infection

Doom, C. M., Turula, H. M. & Hill, A., Sep 30 2009, In : Virology. 392, 2, p. 153-161 9 p.

Research output: Contribution to journalArticle

Muromegalovirus
Norovirus
Cytomegalovirus Infections
Infection
Specific Pathogen-Free Organisms
38 Citations (Scopus)

Iodothyronamines are oxidatively deaminated to iodothyroacetic acids in vivo

Wood, W. J. L., Geraci, T., Nilsen, A., De Barber, A. & Scanlan, T. T., Jan 26 2009, In : ChemBioChem. 10, 2, p. 361-365 5 p.

Research output: Contribution to journalArticle

Acids
Oxidoreductases
Iproniazid
Amine Oxidase (Copper-Containing)
Tissue Extracts
13 Citations (Scopus)

It's all in the family: Multiple toll-like receptors offer promise as novel therapeutic targets for stroke neuroprotection

Leung, P. Y., Packard, A. E. B. & Stenzel-Poore, M., 2009, In : Future Neurology. 4, 2, p. 201-208 8 p.

Research output: Contribution to journalArticle

Toll-Like Receptors
Stroke
Biological Phenomena
Ischemic Preconditioning
Anti-Inflammatory Agents
90 Citations (Scopus)

Ly49P recognition of cytomegalovirus-infected cells expressing H2-D k and CMV-encoded m04 correlates with the NK cell antiviral response

Kielczewska, A., Pyzik, M., Sun, T., Krmpotic, A., Lodoen, M. B., Munks, M., Babic, M., Hill, A., Koszinowski, U. H., Jonjic, S., Lanier, L. L. & Vidal, S. M., Mar 16 2009, In : Journal of Experimental Medicine. 206, 3, p. 515-523 9 p.

Research output: Contribution to journalArticle

Muromegalovirus
Cytomegalovirus
Natural Killer Cells
Antiviral Agents
Cytomegalovirus Infections
8 Citations (Scopus)

Plasma adiponectin levels are increased despite insulin resistance in corticotropin-releasing hormone transgenic mice, an animal model of Cushing syndrome

Shinahara, M., Nishiyama, M., Iwasaki, Y., Nakayama, S., Noguchi, T., Kambayashi, M., Okada, Y., Tsuda, M., Stenzel-Poore, M., Hashimoto, K. & Terada, Y., 2009, In : Endocrine Journal. 56, 7, p. 879-886 8 p.

Research output: Contribution to journalArticle

Genetically Modified Animals
Cushing Syndrome
Corticotropin-Releasing Hormone
Adiponectin
Transgenic Mice
9 Citations (Scopus)

Silicate Nephrolithiasis After Ingestion of Supplements Containing Silica Dioxide

Flythe, J. E., Rueda, J., Riscoe, M. & Watnick, S., Jul 2009, In : American Journal of Kidney Diseases. 54, 1, p. 127-130 4 p.

Research output: Contribution to journalArticle

Silicates
Nephrolithiasis
Silicon Dioxide
Eating
Calculi
145 Citations (Scopus)

Systemic lipopolysaccharide protects the brain from ischemic injury by reprogramming the response of the brain to stroke: A critical role for IRF3

Marsh, B., Stevens, S. L., Packard, A. E. B., Gopalan, B., Hunter, B., Leung, P. Y., Harrington, C. C. & Stenzel-Poore, M., Aug 5 2009, In : Journal of Neuroscience. 29, 31, p. 9839-9849 11 p.

Research output: Contribution to journalArticle

Brain Injuries
Interferons
Lipopolysaccharides
Stroke
Brain
177 Citations (Scopus)

Toll-like receptor signaling in endogenous neuroprotection and stroke

Marsh, B. J., Williams-Karnesky, R. L. & Stenzel-Poore, M., Feb 6 2009, In : Neuroscience. 158, 3, p. 1007-1020 14 p.

Research output: Contribution to journalArticle

Toll-Like Receptors
Stroke
Wounds and Injuries
Brain Ischemia
Ischemia
20 Citations (Scopus)

Two novel nucleobase/pentamidine transporters from Trypanosoma brucei

Ortiz, D., Sanchez, M., Quecke, P. & Landfear, S., Feb 2009, In : Molecular and Biochemical Parasitology. 163, 2, p. 67-76 10 p.

Research output: Contribution to journalArticle

Pentamidine
Trypanosoma brucei brucei
Purine Nucleosides
Nucleoside Transport Proteins
African Trypanosomiasis
2008
19 Citations (Scopus)

Analysis of human immunodeficiency virus matrix domain replacements

Scholz, I., Still, A., Dhenub, T. C., Coday, K., Webb, M. & Barklis, E., Feb 20 2008, In : Virology. 371, 2, p. 322-335 14 p.

Research output: Contribution to journalArticle

Virion
HIV
gag Gene Products
HIV-1
Membranes
10 Citations (Scopus)

An expression system to screen for inhibitors of parasite glucose transporters

Feistel, T., Hodson, C. A., Peyton, D. H. & Landfear, S., Nov 2008, In : Molecular and Biochemical Parasitology. 162, 1, p. 71-76 6 p.

Research output: Contribution to journalArticle

Facilitative Glucose Transport Proteins
Parasites
Leishmania mexicana
Trypanosoma brucei brucei
Plasmodium falciparum
200 Citations (Scopus)

Characterization of the human cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and endothelial cells

Ryckman, B. J., Rainish, B. L., Chase, M. C., Borton, J. A., Nelson, J., Jarvis, M. A. & Johnson, D., Jan 2008, In : Journal of Virology. 82, 1, p. 60-70 11 p.

Research output: Contribution to journalArticle

Human herpesvirus 5
Cytomegalovirus
endothelial cells
epithelial cells
Endothelial Cells
51 Citations (Scopus)

Corticotropin-releasing factor-1 receptor involvement in behavioral neuroadaptation to ethanol: A urocortin1-independent mechanism

Pastor, R., McKinnon, C. S., Scibelli, A. C., Burkhart-Kasch, S., Reed, C., Ryabinin, A., Coste, S. C., Stenzel-Poore, M. & Phillips, T., Jul 1 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 26, p. 9070-9075 6 p.

Research output: Contribution to journalArticle

Corticotropin-Releasing Hormone
Ethanol
Urocortins
Glucocorticoid Receptors
Corticosterone
23 Citations (Scopus)

Drugs and Transporters in Kinetoplastid Protozoa

Landfear, S., 2008, In : Advances in Experimental Medicine and Biology. 625, p. 22-32 11 p.

Research output: Contribution to journalArticle

Protozoa
Membrane Transport Proteins
Parasites
Pharmaceutical Preparations
Leishmania major
118 Citations (Scopus)
Virus Internalization
Cytomegalovirus
Epithelial Cells
Fibroblasts
Cytomegalovirus Infections
60 Citations (Scopus)

Herpes simplex virus gE/gI and US9 proteins promote transport of both capsids and virion glycoproteins in neuronal axons

Snyder, A., Polcicova, K. & Johnson, D., Nov 2008, In : Journal of Virology. 82, 21, p. 10613-10624 12 p.

Research output: Contribution to journalArticle

herpes simplex
capsid
protein transport
Capsid
Protein Transport
97 Citations (Scopus)

Human cytomegalovirus glycoproteins gB and gH/gL mediate epithelial cell-cell fusion when expressed either in cis or in trans

Vanarsdall, A., Ryckman, B. J., Chase, M. C. & Johnson, D., Dec 2008, In : Journal of Virology. 82, 23, p. 11837-11850 14 p.

Research output: Contribution to journalArticle

Human herpesvirus 5
cell fusion
Cell Fusion
glycoproteins
epithelial cells
511 Citations (Scopus)

Mechanisms of ischemic brain damage

Doyle, K. P., Simon, R. P. & Stenzel-Poore, M., Sep 2008, In : Neuropharmacology. 55, 3, p. 310-318 9 p.

Research output: Contribution to journalArticle

Stroke
Brain
Brain Injuries
Cause of Death
Oxidative Stress
197 Citations (Scopus)

Memory Inflation during Chronic Viral Infection Is Maintained by Continuous Production of Short-Lived, Functional T Cells

Snyder, C. M., Cho, K. S., Bonnett, E. L., van Dommelen, S., Shellam, G. R. & Hill, A., Oct 17 2008, In : Immunity. 29, 4, p. 650-659 10 p.

Research output: Contribution to journalArticle

Economic Inflation
Virus Diseases
Muromegalovirus
T-Lymphocytes
Cytomegalovirus Infections
51 Citations (Scopus)

MHC class I immune evasion in MCMV infection

Doom, C. M. & Hill, A., Jun 2008, In : Medical Microbiology and Immunology. 197, 2, p. 191-204 14 p.

Research output: Contribution to journalArticle

Muromegalovirus
Immune Evasion
Cytomegalovirus Infections
Major Histocompatibility Complex
Immunocompetence
67 Citations (Scopus)

Nasal administration of osteopontin peptide mimetics confers neuroprotection in stroke

Doyle, K. P., Yang, T., Lessov, N. S., Ciesielski, T. M., Stevens, S. L., Simon, R. P., King, J. S. & Stenzel-Poore, M., Jun 30 2008, In : Journal of Cerebral Blood Flow and Metabolism. 28, 6, p. 1235-1248 14 p.

Research output: Contribution to journalArticle

Intranasal Administration
Osteopontin
Stroke
Peptides
Thrombin
59 Citations (Scopus)

Subdominant CD8 T-cell epitopes account for protection against cytomegalovirus independent of immunodomination

Holtappels, R., Simon, C. O., Munks, M., Thomas, D., Deegen, P., Kühnapfel, B., Däubner, T., Emde, S. F., Podlech, J., Grzimek, N. K. A., Oehrlein-Karpi, S. A., Hill, A. & Reddehase, M. J., Jun 2008, In : Journal of Virology. 82, 12, p. 5781-5796 16 p.

Research output: Contribution to journalArticle

Cytomegalovirus
T-Lymphocyte Epitopes
epitopes
Epitopes
T-lymphocytes
18 Citations (Scopus)

Synthesis and heme-binding correlation with antimalarial activity of 3,6-bis-(ω-N,N-diethylaminoamyloxy)-4,5-difluoroxanthone

Dodean, R. A., Kelly, J. X., Peyton, D., Gard, G. L., Riscoe, M. & Winter, R. W., Feb 1 2008, In : Bioorganic and Medicinal Chemistry. 16, 3, p. 1174-1183 10 p.

Research output: Contribution to journalArticle

Antimalarials
Heme
Nuclear magnetic resonance
Drug interactions
Fluorine
4 Citations (Scopus)
Congenic Mice
Adoptive Transfer
Staining and Labeling
T-Lymphocytes
Antigens
44 Citations (Scopus)

Th1 and Th2 cells form morphologically distinct immunological synapses

Thauland, T. J., Koguchi, Y., Wetzel, S. A., Dustin, M. L. & Parker, D., 2008, In : Journal of Immunology. 181, 1, p. 393-399 7 p.

Research output: Contribution to journalArticle

Immunological Synapses
Th2 Cells
Th1 Cells
Intercellular Adhesion Molecule-1
Fibroblasts
45 Citations (Scopus)

The dynamics of mouse cytomegalovirus-specific CD4 T cell responses during acute and latent infection

Walton, S. M., Wyrsch, P., Munks, M., Zimmermann, A., Hengel, H., Hill, A. & Oxenius, A., Jul 15 2008, In : Journal of Immunology. 181, 2, p. 1128-1134 7 p.

Research output: Contribution to journalArticle

Muromegalovirus
T-Lymphocytes
Infection
Peptide Library
T-Lymphocyte Epitopes
129 Citations (Scopus)

Toll-like receptor 9: A new target of ischemic preconditioning in the brain

Stevens, S. L., Ciesielski, T. M. P., Marsh, B. J., Yang, T., Homen, D. S., Boule, J. L., Lessov, N. S., Simon, R. P. & Stenzel-Poore, M., May 2008, In : Journal of Cerebral Blood Flow and Metabolism. 28, 5, p. 1040-1047 8 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 9
Ischemic Preconditioning
Oligodeoxyribonucleotides
Tumor Necrosis Factor-alpha
Toll-Like Receptor 4
32 Citations (Scopus)

Toll-like receptors: novel pharmacological targets for the treatment of neurological diseases

Marsh, B. J. & Stenzel-Poore, M., Feb 2008, In : Current Opinion in Pharmacology. 8, 1, p. 8-13 6 p.

Research output: Contribution to journalArticle

Toll-Like Receptors
Pharmacology
Neoplasms
Stroke
2007
27 Citations (Scopus)

A herpes simplex virus gD-YFP fusion glycoprotein is transported separately from viral capsids in neuronal axons

Snyder, A., Bruun, B., Browne, H. M. & Johnson, D., Aug 2007, In : Journal of Virology. 81, 15, p. 8337-8340 4 p.

Research output: Contribution to journalArticle

herpes simplex
capsid
Capsid
Simplexvirus
axons
72 Citations (Scopus)

CXCR3-dependent recruitment of antigen-specific T lymphocytes to the liver during murine cytomegalovirus infection

Hokeness, K. L., Deweerd, E. S., Munks, M., Lewis, C. A., Gladue, R. P. & Salazar-Mather, T. P., Feb 2007, In : Journal of Virology. 81, 3, p. 1241-1250 10 p.

Research output: Contribution to journalArticle

Muromegalovirus
Cytomegalovirus Infections
T-lymphocytes
antigens
T-Lymphocytes
61 Citations (Scopus)

Cytoplasmic residues of herpes simplex virus glycoprotein gE required for secondary envelopment and binding of tegument proteins VP22 and UL11 to gE and gD

Farnsworth, A., Wisner, T. W. & Johnson, D., Jan 2007, In : Journal of Virology. 81, 1, p. 319-331 13 p.

Research output: Contribution to journalArticle

herpes simplex
Simplexvirus
binding proteins
glycoproteins
Glycoproteins