Research Output 1969 2019

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2011
37 Citations (Scopus)

Anterograde transport of herpes simplex virus capsids in neurons by both separate and married mechanisms

Wisner, T. W., Sugimoto, K., Howard, P. W., Kawaguchi, Y. & Johnson, D., Jun 2011, In : Journal of Virology. 85, 12, p. 5919-5928 10 p.

Research output: Contribution to journalArticle

herpes simplex
capsid
Capsid
Simplexvirus
axons
22 Citations (Scopus)

Comparing the kinetics of NK cells, CD4, and CD8 T cells in murine cytomegalovirus infection

Schlub, T. E., Sun, J. C., Walton, S. M., Robbins, S. H., Pinto, A. K., Munks, M., Hill, A., Brossay, L., Oxenius, A. & Davenport, M. P., Aug 1 2011, In : Journal of Immunology. 187, 3, p. 1385-1392 8 p.

Research output: Contribution to journalArticle

Muromegalovirus
Cytomegalovirus Infections
Natural Killer Cells
T-Lymphocytes
Innate Immunity
9 Citations (Scopus)

Corticotropin-releasing hormone (CRH) transgenic mice display hyperphagia with increased Agouti-related protein mRNA in the hypothalamic arcuate nucleus

Nakayama, S., Nishiyama, M., Iwasaki, Y., Shinahara, M., Okada, Y., Tsuda, M., Okazaki, M., Tsugita, M., Taguchi, T., Makino, S., Stenzel-Poore, M., Hashimoto, K. & Terada, Y., 2011, In : Endocrine Journal. 58, 4, p. 279-286 8 p.

Research output: Contribution to journalArticle

Agouti-Related Protein
Hyperphagia
Arcuate Nucleus of Hypothalamus
Corticotropin-Releasing Hormone
Transgenic Mice
21 Citations (Scopus)

CRF receptor antagonist astressin-B reverses and prevents alopecia in CRF over-expressing mice

Wang, L., Million, M., Rivier, J., Rivier, C., Craft, N., Stenzel-Poore, M. & Taché, Y., 2011, In : PLoS One. 6, 2, e16377.

Research output: Contribution to journalArticle

Corticotropin-Releasing Hormone Receptors
corticotropin-releasing hormone
alopecia
Corticotropin-Releasing Hormone
Alopecia
7 Citations (Scopus)

Cyclosporine-resistant, Rab27a-independent mobilization of intracellular preformed CD40 ligand mediates antigen-specific T cell help in vitro

Koguchi, Y., Gardell, J. L., Thauland, T. J. & Parker, D., Jul 15 2011, In : Journal of Immunology. 187, 2, p. 626-634 9 p.

Research output: Contribution to journalArticle

CD40 Ligand
Cyclosporine
T-Lymphocytes
Antigens
In Vitro Techniques
13 Citations (Scopus)

Determinants of the HIV-1 core assembly pathway

Lopez, C., Eccles, J. D., Still, A., Sloan, R. E., Barklis, R. L., Tsagli, S. M. & Barklis, E., Aug 15 2011, In : Virology. 417, 1, p. 137-146 10 p.

Research output: Contribution to journalArticle

Capsid
HIV-1
Cyclophilins
Capsid Proteins
Proteins
21 Citations (Scopus)

Dissection of corticotropin-releasing factor system involvement in locomotor sensitivity to methamphetamine

Giardino, W. J., Pastor, R., Anacker, A. M. J., Spangler, E., Cote, D. M., Li, J., Stenzel-Poore, M., Phillips, T. & Ryabinin, A., Feb 2011, In : Genes, Brain and Behavior. 10, 1, p. 78-89 12 p.

Research output: Contribution to journalArticle

Methamphetamine
Corticotropin-Releasing Hormone
Dissection
Urocortins
Knockout Mice
19 Citations (Scopus)

Ethanol concentration-dependent effects and the role of stress on ethanol drinking in corticotropin-releasing factor type 1 and double type 1 and 2 receptor knockout mice

Pastor, R., Reed, C., Burkhart-Kasch, S., Li, N., Sharpe, A. L., Coste, S. C., Stenzel-Poore, M. & Phillips, T., Nov 2011, In : Psychopharmacology. 218, 1, p. 169-177 9 p.

Research output: Contribution to journalArticle

Corticotropin-Releasing Hormone
Knockout Mice
Drinking
Ethanol
Saccharin
21 Citations (Scopus)

Herpes simplex virus glycoproteins gB and gD function in a redundant fashion to promote secondary envelopment

Johnson, D., Wisner, T. W. & Wright, C. C., May 2011, In : Journal of Virology. 85, 10, p. 4910-4926 17 p.

Research output: Contribution to journalArticle

herpes simplex
Simplexvirus
glycoproteins
Glycoproteins
viruses
263 Citations (Scopus)

Herpesviruses remodel host membranes for virus egress

Johnson, D. & Baines, J. D., May 2011, In : Nature Reviews Microbiology. 9, 5, p. 382-394 13 p.

Research output: Contribution to journalArticle

Virus Release
Capsid
Herpesviridae
Nuclear Envelope
Membranes
49 Citations (Scopus)

HIV-1 matrix protein binding to RNA

Alfadhli, A., McNett, H., Tsagli, S., Bächinger, H. P., Peyton, D. H. & Barklis, E., Jul 22 2011, In : Journal of Molecular Biology. 410, 4, p. 653-666 14 p.

Research output: Contribution to journalArticle

RNA-Binding Proteins
HIV-1
RNA
gag Gene Products
HIV
54 Citations (Scopus)
Viral Interference
Human herpesvirus 5
Cytomegalovirus
Virus Internalization
fibroblasts
26 Citations (Scopus)

Low-pH-dependent changes in the conformation and oligomeric state of the prefusion form of herpes simplex virus glycoprotein B are separable from fusion activity

Dollery, S. J., Wright, C. C., Johnson, D. & Nicola, A. V., Oct 2011, In : Journal of Virology. 85, 19, p. 9964-9973 10 p.

Research output: Contribution to journalArticle

herpes simplex
Simplexvirus
glycoproteins
Glycoproteins
viruses
89 Citations (Scopus)

LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury

Vartanian, K. B., Stevens, S. L., Marsh, B. J., Williams-Karnesky, R., Lessov, N. S. & Stenzel-Poore, M., Oct 14 2011, In : Journal of Neuroinflammation. 8, 140.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Lipopolysaccharides
Stroke
Wounds and Injuries
Brain Ischemia
10 Citations (Scopus)

Lysosomal degradation of Leishmania hexose and inositol transporters is regulated in a stage-, nutrient- and ubiquitin-dependent manner

Vince, J. E., Tull, D., Landfear, S. & McConville, M. J., Jun 2011, In : International Journal for Parasitology. 41, 7, p. 791-800 10 p.

Research output: Contribution to journalArticle

Monosaccharide Transport Proteins
Leishmania
Inositol
Ubiquitin
Hexoses
68 Citations (Scopus)

Minireview: Computational prediction of type III and IV secreted effectors in gram-negative bacteria

McDermott, J. E., Corrigan, A., Peterson, E., Oehmen, C., Niemann, G., Cambronne, E., Sharp, D., Adkins, J. N., Samudrala, R. & Heffron, F., Jan 2011, In : Infection and Immunity. 79, 1, p. 23-32 10 p.

Research output: Contribution to journalArticle

Gram-Negative Bacteria
Host-Pathogen Interactions
Proteins
Bacteria
7 Citations (Scopus)

Mycobacterium smegmatis RoxY is a repressor of oxyS and contributes to resistance to oxidative stress and bactericidal ubiquitin-derived peptides

Daugherty, A., Powers, K. M., Standley, M. S., Kim, C. S. & Purdy, G., Dec 2011, In : Journal of Bacteriology. 193, 24, p. 6824-6833 10 p.

Research output: Contribution to journalArticle

Mycobacterium smegmatis
Ubiquitin
Oxidative Stress
Peptides
Genes
37 Citations (Scopus)

NF-κB-inducing kinase plays an essential T cell-intrinsic role in graft-versus-host disease and lethal autoimmunity in mice

Murray, S., Polesso, F., Rowe, A. M., Basak, S., Koguchi, Y., Toren, K. G., Hoffmann, A. & Parker, D., Dec 1 2011, In : Journal of Clinical Investigation. 121, 12, p. 4775-4786 12 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
Autoimmunity
Phosphotransferases
T-Lymphocytes
Tumor Necrosis Factor Receptors
37 Citations (Scopus)

Nutrient transport and pathogenesis in selected parasitic protozoa

Landfear, S., Apr 2011, In : Eukaryotic Cell. 10, 4, p. 483-493 11 p.

Research output: Contribution to journalArticle

Parasites
Food
Membrane Transport Proteins
Purines
Hexoses
47 Citations (Scopus)

Optimization of endochin-like quinolones for antimalarial activity

Winter, R., Kelly, J. X., Smilkstein, M. J., Hinrichs, D., Koop, D. & Riscoe, M., Feb 2011, In : Experimental Parasitology. 127, 2, p. 545-551 7 p.

Research output: Contribution to journalArticle

Quinolones
Antimalarials
Acridones
Atovaquone
Plasmodium falciparum
44 Citations (Scopus)

Peptides from cytomegalovirus UL130 and UL131 proteins induce high titer antibodies that block viral entry into mucosal epithelial cells

Saccoccio, F. M., Sauer, A. L., Cui, X., Armstrong, A. E., Habib, EL. S. E., Johnson, D., Ryckman, B. J., Klingelhutz, A. J., Adler, S. P. & McVoy, M. A., Mar 24 2011, In : Vaccine. 29, 15, p. 2705-2711 7 p.

Research output: Contribution to journalArticle

Viral Antibodies
Cytomegalovirus
epithelial cells
Epithelial Cells
peptides
37 Citations (Scopus)

Proof of concept: Pharmacological preconditioning with a Toll-like receptor agonist protects against cerebrovascular injury in a primate model of stroke

Bahjat, F., Williams-Karnesky, R. L., Kohama, S., West, G. A., Doyle, K. P., Spector, M. D., Hobbs, T. & Stenzel-Poore, M., May 2011, In : Journal of Cerebral Blood Flow and Metabolism. 31, 5, p. 1229-1242 14 p.

Research output: Contribution to journalArticle

Toll-Like Receptors
Primates
Stroke
Wounds and Injuries
Toll-Like Receptor 9
50 Citations (Scopus)

Reductions in claudin-1 may enhance susceptibility to herpes simplex virus 1 infections in atopic dermatitis

De Benedetto, A., Slifka, M., Rafaels, N. M., Kuo, I. H., Georas, S. N., Boguniewicz, M., Hata, T., Schneider, L. C., Hanifin, J., Gallo, R. L., Johnson, D., Barnes, K. C., Leung, D. Y. M. & Beck, L. A., Jul 2011, In : Journal of Allergy and Clinical Immunology. 128, 1, p. 242-246 5 p.

Research output: Contribution to journalArticle

Kaposi Varicelliform Eruption
Claudin-1
Tight Junctions
Human Herpesvirus 1
Virus Diseases
6 Citations (Scopus)

Remodeling of protein and mRNA expression in Leishmania mexicana induced by deletion of glucose transporter genes

Feng, X., Feistel, T., Buffalo, C., McCormack, A., Kruvand, E., Rodriguez-Contreras, D., Akopyants, N. S., Umasankar, P. K., David, L., Jardim, A., Beverley, S. M. & Landfear, S., Jan 2011, In : Molecular and Biochemical Parasitology. 175, 1, p. 39-48 10 p.

Research output: Contribution to journalArticle

Leishmania mexicana
Facilitative Glucose Transport Proteins
Messenger RNA
Parasites
Genes
28 Citations (Scopus)

Report from the second cytomegalovirus and immunosenescence workshop

Wills, M., Akbar, A., Beswick, M., Bosch, J. A., Caruso, C., Colonna-Romano, G., Dutta, A., Franceschi, C., Fulop, T., Gkrania-Klotsas, E., Goronzy, J., Griffiths, S. J., Henson, S. M., Herndler-Brandstetter, D., Hill, A., Kern, F., Klenerman, P., Macallan, D., Macaulay, R., Maier, A. B. & 19 others, Mason, G., Melzer, D., Morgan, M., Moss, P., Nikolich-Zugich, J., Pachnio, A., Riddell, N., Roberts, R., Sansoni, P., Sauce, D., Sinclair, J., Solana, R., Strindhall, J., Trzonkowski, P., van Lier, R., Vescovini, R., Wang, G., Westendorp, R. & Pawelec, G., Oct 28 2011, In : Immunity and Ageing. 8, 10.

Research output: Contribution to journalArticle

Cytomegalovirus
T-Lymphocytes
Education
Economic Inflation
Vaccination
26 Citations (Scopus)

Second-site compensatory mutations of HIV-1 capsid mutations

Noviello, C. M., Lopez, C., Kukull, B., McNett, H., Still, A., Eccles, J., Sloan, R. & Barklis, E., May 2011, In : Journal of Virology. 85, 10, p. 4730-4738 9 p.

Research output: Contribution to journalArticle

capsid
Capsid
Human immunodeficiency virus 1
HIV-1
mutation
66 Citations (Scopus)

Sustained CD8+ T cell memory inflation after infection with a single-cycle Cytomegalovirus

Snyder, C. M., Cho, K. S., Bonnett, E. L., Allan, J. E. & Hill, A., Oct 2011, In : PLoS Pathogens. 7, 10, e1002295.

Research output: Contribution to journalArticle

Economic Inflation
Cytomegalovirus
Viruses
T-Lymphocytes
Infection
6 Citations (Scopus)
Ubiquitin
Lysosomes
Mycobacterium tuberculosis
Macrophages
Peptides

The 50th midwinter conference of immunologists at asilomar

Parker, D., May 2011, In : Nature Immunology. 12, 7, p. 583-585 3 p.

Research output: Contribution to journalArticle

Anniversaries and Special Events
Allergy and Immunology
Immune System

When the Going Gets Tough, Memory T Cells Check Out

Hill, A., Aug 26 2011, In : Immunity. 35, 2, p. 158-160 3 p.

Research output: Contribution to journalArticle

Immunity
T-Lymphocytes
2010
31 Citations (Scopus)

Adaptive responses to purine starvation in Leishmania donovani

Carter, N., Yates, P., Gessford, S. K., Galagan, S. R., Landfear, S. & Ullman, B., Oct 2010, In : Molecular Microbiology. 78, 1, p. 92-107 16 p.

Research output: Contribution to journalArticle

Leishmania donovani
Starvation
Purine Nucleosides
Purines
Parasites
84 Citations (Scopus)

A human cytomegalovirus gO-null mutant fails to incorporate gH/gL into the virion envelope and is unable to enter fibroblasts and epithelial and endothelial cells

Wille, P. T., Knoche, A. J., Nelson, J., Jarvis, M. A. & Johnson, D., Mar 2010, In : Journal of Virology. 84, 5, p. 2585-2596 12 p.

Research output: Contribution to journalArticle

Human herpesvirus 5
Cytomegalovirus
virion
Virion
endothelial cells
10 Citations (Scopus)

Anergic CD4+ T cells form mature immunological synapses with enhanced accumulation of c-Cbl and Cbl-b

Doherty, M., Osborne, D. G., Browning, D. L., Parker, D. & Wetzel, S. A., Apr 1 2010, In : Journal of Immunology. 184, 7, p. 3598-3608 11 p.

Research output: Contribution to journalArticle

Immunological Synapses
Synapses
T-Lymphocytes
Peptides
Phosphotyrosine
391 Citations (Scopus)

Chemical genetics of Plasmodium falciparum

Guiguemde, W. A., Shelat, A. A., Bouck, D., Duffy, S., Crowther, G. J., Davis, P. H., Smithson, D. C., Connelly, M., Clark, J., Zhu, F., Jiménez-Díaz, M. B., Martinez, M. S., Wilson, E. B., Tripathi, A. K., Gut, J., Sharlow, E. R., Bathurst, I., Mazouni, F. E., Fowble, J. W., Forquer, I. & 15 others, McGinley, P. L., Castro, S., Angulo-Barturen, I., Ferrer, S., Rosenthal, P. J., Derisi, J. L., Sullivan, D. J., Lazo, J. S., Roos, D. S., Riscoe, M., Phillips, M. A., Rathod, P. K., Van Voorhis, W. C., Avery, V. M. & Guy, R. K., May 20 2010, In : Nature. 465, 7296, p. 311-315 5 p.

Research output: Contribution to journalArticle

Antimalarials
Plasmodium falciparum
Reverse Genetics
Falciparum Malaria
Toxoplasma
8 Citations (Scopus)

CRF2 null mutation increases sensitivity to isolation rearing effects on locomotor activity in mice

Gresack, J., Powell, S., Geyer, M., Stenzel-Poore, M., Coste, S. & Risbrough, V., Aug 2010, In : Neuropeptides. 44, 4, p. 349-353 5 p.

Research output: Contribution to journalArticle

Exploratory Behavior
Locomotion
Mutation
Social Isolation
Gene Knockout Techniques
49 Citations (Scopus)

Cross-presentation of a spread-defective MCMV is sufficient to prime the majority of virus-specific CD8+ T cells

Snyder, C. M., Allan, J. E., Bonnett, E. L., Doom, C. M. & Hill, A., Mar 12 2010, In : PLoS One. 5, 3, e9681.

Research output: Contribution to journalArticle

Cross-Priming
Muromegalovirus
Cytomegalovirus
T-cells
Viruses
35 Citations (Scopus)

Diversity in immunological synapse structure

Thauland, T. J. & Parker, D., Dec 2010, In : Immunology. 131, 4, p. 466-472 7 p.

Research output: Contribution to journalArticle

Immunological Synapses
T-Lymphocytes
T-Cell Antigen Receptor
Major Histocompatibility Complex
Peptides
10 Citations (Scopus)

Glucose transporters in parasitic protozoa.

Landfear, S., 2010, In : Methods in molecular biology (Clifton, N.J.). 637, p. 245-262 18 p.

Research output: Contribution to journalArticle

Facilitative Glucose Transport Proteins
Parasites
Leishmania
Malaria
Monosaccharide Transport Proteins
40 Citations (Scopus)

Human cytomegalovirus TR strain glycoprotein O acts as a chaperone promoting gH/gL incorporation into virions but is not present in virions

Ryckman, B. J., Chase, M. C. & Johnson, D., Mar 2010, In : Journal of Virology. 84, 5, p. 2597-2609 13 p.

Research output: Contribution to journalArticle

Human herpesvirus 5
Cytomegalovirus
virion
Virion
endothelial cells
33 Citations (Scopus)

Isolation rearing-induced deficits in contextual fear learning do not require CRF2 receptors

Gresack, J. E., Risbrough, V. B., Scott, C. N., Coste, S., Stenzel-Poore, M., Geyer, M. A. & Powell, S. B., May 1 2010, In : Behavioural Brain Research. 209, 1, p. 80-84 5 p.

Research output: Contribution to journalArticle

Fear
Learning
Freezing
Weaning
Cues
14 Citations (Scopus)

Purine restriction induces pronounced translational upregulation of the NT1 adenosine/pyrimidine nucleoside transporter in Leishmania major

Ortiz, D., Valdés, R., Sanchez, M., Hayenga, J., Elya, C., Detke, S. & Landfear, S., Oct 2010, In : Molecular Microbiology. 78, 1, p. 108-118 11 p.

Research output: Contribution to journalArticle

Nucleoside Transport Proteins
Pyrimidine Nucleosides
Leishmania major
Purines
Adenosine
49 Citations (Scopus)

Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action

Dikeakos, J. D., Atkins, K. M., Thomas, L., Emert-Sedlak, L., Byeon, I. J. L., Jung, J., Ahn, J., Wortman, M. D., Kukull, B., Saito, M., Koizumi, H., Williamson, D. M., Hiyoshi, M., Barklis, E., Takiguchi, M., Suzu, S., Gronenborn, A. M., Smithgall, T. E. & Thomas, G., Oct 1 2010, In : Molecular Biology of the Cell. 21, 19, p. 3279-3292 14 p.

Research output: Contribution to journalArticle

HIV-1
Down-Regulation
src-Family Kinases
Phosphotransferases
T-Lymphocytes
18 Citations (Scopus)

Structure-specific recognition protein 1 facilitates microtubule growth and bundling required for mitosis

Zeng, S. X., Li, Y., Jin, Y., Zhang, Q., Keller, D. M., McQuaw, C. M., Barklis, E., Stone, S., Hoatlin, M., Zhao, Y. & Lu, H., Feb 2010, In : Molecular and Cellular Biology. 30, 4, p. 935-947 13 p.

Research output: Contribution to journalArticle

Mitosis
Microtubules
Growth
Proteins
Chromosomes
36 Citations (Scopus)

Toll-Like receptor tolerance as a mechanism for neuroprotection

Vartanian, K. B. & Stenzel-Poore, M., Dec 2010, In : Translational Stroke Research. 1, 4, p. 252-260 9 p.

Research output: Contribution to journalArticle

Toll-Like Receptors
Stroke
Wounds and Injuries
Neuroprotection
Chromatin Assembly and Disassembly
12 Citations (Scopus)

Transporters for drug delivery and as drug targets in parasitic protozoa

Landfear, S., Jan 2010, In : Clinical Pharmacology and Therapeutics. 87, 1, p. 122-125 4 p.

Research output: Contribution to journalArticle

Parasites
Membrane Transport Proteins
Pharmaceutical Preparations
Neglected Diseases
Essential Drugs
2009
32 Citations (Scopus)

Adenosine and stroke: Maximizing the therapeutic potential of adenosine as a prophylactic and acute neuroprotectant

Williams-Karnesky, R. L. & Stenzel-Poore, M., 2009, In : Current Neuropharmacology. 7, 3, p. 217-227 11 p.

Research output: Contribution to journalArticle

Neuroprotective Agents
Adenosine
Stroke
Purinergic P1 Receptors
Brain Ischemia
37 Citations (Scopus)

Adenovirus vectors expressing hantavirus proteins protect hamsters against lethal challenge with Andes virus

Safronetz, D., Hegde, N. R., Ebihara, H., Denton, M., Kobinger, G. P., St. Jeor, S., Feldmann, H. & Johnson, D., Jul 2009, In : Journal of Virology. 83, 14, p. 7285-7295 11 p.

Research output: Contribution to journalArticle

Hantavirus
Adenoviridae
lethal genes
hamsters
Cricetinae
17 Citations (Scopus)

Amplification of an alternate transporter gene suppresses the avirulent phenotype of glucose transporter null mutants in Leishmania mexicana

Feng, X., Rodriguez-Contreras, D., Buffalo, C., Bouwer, H. G. A., Kruvand, E., Beverley, S. M. & Landfear, S., Jan 2009, In : Molecular Microbiology. 71, 2, p. 369-381 13 p.

Research output: Contribution to journalArticle

Leishmania mexicana
Facilitative Glucose Transport Proteins
Monosaccharide Transport Proteins
Phenotype
Membrane Transport Proteins
20 Citations (Scopus)

An ab initio structural model of a nucleoside permease predicts functionally important residues

Valdés, R., Arastu-Kapur, S., Landfear, S. & Shinde, U., Jul 10 2009, In : Journal of Biological Chemistry. 284, 28, p. 19067-19076 10 p.

Research output: Contribution to journalArticle

Membrane Transport Proteins
Structural Models
Nucleosides
Substrate Specificity
Mutation
22 Citations (Scopus)

An acid-activated nucleobase transporter from Leishmania major

Ortiz, D., Sanchez, M., Koch, H. P., Larson, H. P. & Landfear, S., Jun 12 2009, In : Journal of Biological Chemistry. 284, 24, p. 16164-16169 6 p.

Research output: Contribution to journalArticle

Leishmania major
Macrophages
Adenine
Acids
Protozoa