Research Output 1969 2019

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2019
2 Citations (Scopus)

A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis

Lee, S., Liu, H., Wilen, C. B., Sychev, Z. E., Desai, C., Hykes, B. L., Orchard, R. C., McCune, B. T., Kim, K. W., Nice, T., Handley, S. A., Baldridge, M. T., Amarasinghe, G. K. & Virgin, H. W., Jun 12 2019, In : Cell Host and Microbe. 25, 6, p. 845-857.e5

Research output: Contribution to journalArticle

Viral Nonstructural Proteins
Norovirus
Enterovirus
Vaccination
Vaccines

Caspase-mediated cleavage of murine norovirus NS1/2 potentiates apoptosis and is required for persistent infection of intestinal epithelial cells

Robinson, B. A., Van Winkle, J. A., McCune, B. T., Peters, A. M. & Nice, T., Jul 1 2019, In : PLoS pathogens. 15, 7, e1007940.

Research output: Contribution to journalArticle

Open Access
Norovirus
Caspases
Epithelial Cells
Apoptosis
Infection
1 Citation (Scopus)

Central memory CD8+ T cells become CD69+ tissue-residents during viral skin infection independent of CD62L-mediated lymph node surveillance

Osborn, J. F., Hobbs, S. J., Mooster, J. L., Khan, T. N., Kilgore, A. M., Harbour, J. C. & Nolz, J., Mar 1 2019, In : PLoS pathogens. 15, 3, p. e1007633

Research output: Contribution to journalArticle

Open Access
Virus Diseases
Lymph Nodes
T-Lymphocytes
Skin
Immunity
3 Citations (Scopus)

Ceramides bind VDAC2 to trigger mitochondrial apoptosis

Dadsena, S., Bockelmann, S., Mina, J. G. M., Hassan, D. G., Korneev, S., Razzera, G., Jahn, H., Niekamp, P., Müller, D., Schneider, M., Tafesse, F., Marrink, S. J., Melo, M. N. & Holthuis, J. C. M., Dec 1 2019, In : Nature communications. 10, 1, 1832.

Research output: Contribution to journalArticle

Open Access
Ceramides
apoptosis
glutamates
actuators
Apoptosis
6 Citations (Scopus)

Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms

Zhang, H., Savage, S., Schultz, A. R., Bottomly, D., White, L., Segerdell, E., Wilmot, B., McWeeney, S., Eide, C. A., Nechiporuk, T., Carlos, A., Henson, R., Lin, C., Searles, R., Ho, H., Lam, Y. L., Sweat, R., Follit, C., Jain, V., Lind, E. & 10 others, Borthakur, G., Garcia-Manero, G., Ravandi, F., Kantarjian, H. M., Cortes, J., Collins, R., Buelow, D. R., Baker, S. D., Druker, B. & Tyner, J., Dec 1 2019, In : Nature Communications. 10, 1, 244.

Research output: Contribution to journalArticle

leukemias
mutations
Acute Myeloid Leukemia
Mutation
inhibitors

Codon-Optimization of Wild-Type Adeno-Associated Virus Capsid Sequences Enhances DNA Family Shuffling while Conserving Functionality

Cabanes-Creus, M., Ginn, S. L., Amaya, A. K., Liao, S. H. Y., Westhaus, A., Hallwirth, C. V., Wilmott, P., Ward, J., Dilworth, K. L., Santilli, G., Rybicki, A., Nakai, H., Thrasher, A. J., Filip, A. C., Alexander, I. E. & Lisowski, L., Mar 15 2019, In : Molecular Therapy - Methods and Clinical Development. 12, p. 71-84 14 p.

Research output: Contribution to journalArticle

DNA Shuffling
Dependovirus
Capsid
Codon
Tropism

ELQ-331 as a prototype for extremely durable chemoprotection against malaria

Smilkstein, M. J., Pou, S., Krollenbrock, A., Bleyle, L. A., Dodean, R. A., Frueh, L., Hinrichs, D. J., Li, Y., Martinson, T., Munar, M. Y., Winter, R. W., Bruzual, I., Whiteside, S., Nilsen, A., Koop, D., Kelly, J. X., Kappe, S. H. I., Wilder, B. K. & Riscoe, M., Aug 27 2019, In : Malaria Journal. 18, 1, 291.

Research output: Contribution to journalArticle

Open Access
Malaria
Prodrugs
Plasmodium yoelii
Pharmacokinetics
Sporozoites

Gasdermin-D and caspase-7 are the key caspase-1/8 substrates downstream of the NAIP5/NLRC4 inflammasome required for restriction of legionella pneumophila

Gonçalves, A. V., Margolis, S. R., Quirino, G. F. S., Mascarenhas, D. P. A., Rauch, I., Nichols, R. D., Ansaldo, E., Fontana, M. F., Vance, R. E. & Zamboni, D. S., Jun 1 2019, In : PLoS pathogens. 15, 6, e1007886.

Research output: Contribution to journalArticle

Open Access
Inflammasomes
Caspase 7
Legionella pneumophila
Caspase 1
Caspase 8
1 Citation (Scopus)

HCMV trimer- and pentamer-specific antibodies synergize for virus neutralization but do not correlate with congenital transmission

Vanarsdall, A., Chin, A. L., Liu, J., Jardetzky, T. S., Mudd, J., Orloff, S., Streblow, D., Mussi-Pinhata, M. M., Yamamoto, A. Y., Duarte, G., Britt, W. J. & Johnson, D., Feb 26 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3728-3733 6 p.

Research output: Contribution to journalArticle

Open Access
Cytomegalovirus
Neutralizing Antibodies
Viruses
Antibodies
Mothers

Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis

Bryson, B. D., Rosebrock, T. R., Tafesse, F., Itoh, C. Y., Nibasumba, A., Babunovic, G. H., Corleis, B., Martin, C., Keegan, C., Andrade, P., Realegeno, S., Kwon, D., Modlin, R. L. & Fortune, S. M., Dec 1 2019, In : Nature communications. 10, 1, 2329.

Research output: Contribution to journalArticle

Open Access
tuberculosis
macrophages
Macrophages
Granulocyte-Macrophage Colony-Stimulating Factor
Mycobacterium tuberculosis
1 Citation (Scopus)

IFN-I and IL-22 mediate protective effects of intestinal viral infection

Neil, J. A., Matsuzawa-Ishimoto, Y., Kernbauer-Hölzl, E., Schuster, S. L., Sota, S., Venzon, M., Dallari, S., Galvao Neto, A., Hine, A., Hudesman, D., Loke, P., Nice, T. & Cadwell, K., Jan 1 2019, In : Nature Microbiology.

Research output: Contribution to journalArticle

Norovirus
Virus Diseases
Citrobacter rodentium
Epithelial Cells
Interferon Type I

Legionella dismantles linear ubiquitin

Damgaard, R. B. & Pruneda, J., Aug 1 2019, In : Nature Microbiology. 4, 8, p. 1244-1245 2 p.

Research output: Contribution to journalArticle

Legionella
Ubiquitin
Legionnaires' Disease
Legionella pneumophila
Bacterial Infections
3 Citations (Scopus)

Microbial Colonization Activates an Immune Fight-and-Flight Response via Neuroendocrine Signaling

Singh, J. & Aballay, A., Apr 8 2019, In : Developmental Cell. 49, 1, p. 89-99.e4

Research output: Contribution to journalArticle

Genes
Caenorhabditis elegans
Intestines
Pathogens
Aptitude
3 Citations (Scopus)

Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum (PfNDH2) is dispensable in the asexual blood stages

Ke, H., Ganesan, S. M., Dass, S., Morrisey, J. M., Pou, S., Nilsen, A., Riscoe, M., Mather, M. W. & Vaidya, A. B., Apr 1 2019, In : PloS one. 14, 4, e0214023.

Research output: Contribution to journalArticle

Open Access
NADH dehydrogenase
Plasmodium falciparum
Parasites
antimalarials
Blood
3 Citations (Scopus)

MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine

Su, C. C., Klenotic, P. A., Bolla, J. R., Purdy, G., Robinson, C. V. & Yu, E. W., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 166, 23, p. 11241-11246 6 p.

Research output: Contribution to journalArticle

Membrane Proteins
Lipids
Cord Factors
Mycolic Acids
Cell Wall

Multiple-stage precursor ion separation and high resolution mass spectrometry toward structural characterization of 2,3-diacyltrehalose family from mycobacterium tuberculosis

Frankfater, C., Abramovitch, R. B., Purdy, G., Turk, J., Legentil, L., Lemiègre, L. & Hsu, F. F., Mar 1 2019, In : Separations. 6, 1, 4.

Research output: Contribution to journalArticle

Open Access
Trehalose
Mass spectrometry
Ions
Stereoisomerism
Complex Mixtures

Organization of Farnesylated, Carboxymethylated KRAS4B on Membranes

Barklis, E., Stephen, A. G., Staubus, A. O., Barklis, R. L. & Alfadhli, A., Jan 1 2019, In : Journal of molecular biology.

Research output: Contribution to journalArticle

Membranes
Proteins
Prenylation
ras Proteins
Post Translational Protein Processing

Sensing What's Out There – Kinetoplastid Parasites

Landfear, S. & Zilberstein, D., Jan 1 2019, (Accepted/In press) In : Trends in Parasitology.

Research output: Contribution to journalArticle

Parasites
Trypanosomiasis
Leishmania
Signal Transduction
Membrane Proteins
1 Citation (Scopus)

Similar neural pathways control foraging in mosquitoes and worms

Singh, J. & Aballay, A., Mar 1 2019, In : mBio. 10, 2, e00656-19.

Research output: Contribution to journalArticle

Open Access
Neural Pathways
Neuropeptide Y Receptors
Culicidae
Disease Vectors
Caenorhabditis elegans

Targeting mitochondria in cancer therapy could provide a basis for the selective anticancer activity

Rozanov, D., Cheltsov, A., Nilsen, A., Boniface, C., Forquer, I., Korkola, J., Gray, J., Tyner, J., Tognon, C. E., Mills, G. & Spellman, P., Mar 1 2019, In : PloS one. 14, 3, e0205623.

Research output: Contribution to journalArticle

Open Access
Mitochondria
Assays
mitochondria
therapeutics
neoplasms
2 Citations (Scopus)

The brief case: Klebsiella variicola-identifying the misidentified

Fontana, L., Bonura, E., Lyski, Z. & Messer, W., Jan 1 2019, In : Journal of Clinical Microbiology. 57, 1, e00826.

Research output: Contribution to journalArticle

Klebsiella
2018

Antiplasmodial evaluation of Anacardium occidentale and alkyl-phenols

Gimenez, V. M. M., Alvarenga, T. A., Groppo, M., Silva, M. L. A. E., Cunha, W. R., Januário, A. H., Smilkstein, M. J., Riscoe, M. & Pauletti, P. M., Jan 1 2018, (Accepted/In press) In : Brazilian Journal of Pharmacognosy.

Research output: Contribution to journalArticle

Anacardium
Phenols
Inhibitory Concentration 50
Anacardic Acids
Ethanol

A quantitative dot blot assay for AAV titration and its use for functional assessment of the adeno-associated virus assembly-activating proteins

Powers, J. M., Chang, X. L., Song, Z. & Nakai, H., Jun 12 2018, In : Journal of Visualized Experiments. 2018, 136, e56766.

Research output: Contribution to journalArticle

Functional assessment
Virus Assembly
Dependovirus
Titration
Viruses
8 Citations (Scopus)

CD147 promotes entry of pentamer-expressing human cytomegalovirus into epithelial and endothelial cells

Vanarsdall, A., Pritchard, S. R., Wisner, T. W., Liu, J., Jardetzky, T. S. & Johnson, D., May 1 2018, In : mBio. 9, 3, e00781-18.

Research output: Contribution to journalArticle

Cytomegalovirus
Endothelial Cells
Epithelial Cells
Fibroblasts
Glycoproteins
2 Citations (Scopus)

Characterization and structure-activity relationship analysis of a class of antiviral compounds that directly bind dengue virus capsid protein and are incorporated into virions

Smith, J. L., Sheridan, K., Parkins, C. J., Frueh, L., Jemison, A. L., Strode, K., Dow, G., Nilsen, A. & Hirsch, A., Jul 1 2018, In : Antiviral Research. 155, p. 12-19 8 p.

Research output: Contribution to journalArticle

Dengue Virus
Capsid Proteins
Structure-Activity Relationship
Virion
Antiviral Agents
10 Citations (Scopus)

Dominant-negative STAT5B mutations cause growth hormone insensitivity with short stature and mild immune dysregulation

Klammt, J., Neumann, D., Gevers, E. F., Andrew, S. F., Schwartz, I. D., Rockstroh, D., Colombo, R., Sanchez, M., Vokurkova, D., Kowalczyk, J., Metherell, L. A., Rosenfeld, R. R., Pfäffle, R., Dattani, M. T., Dauber, A. & Hwa, V., Dec 1 2018, In : Nature Communications. 9, 1, 8329.

Research output: Contribution to journalArticle

Laron Syndrome
pituitary hormones
mutations
Transducers
Growth Hormone
3 Citations (Scopus)

Emerging alphaviruses are sensitive to cellular states induced by a novel small-molecule agonist of the STING pathway

Gall, B., Pryke, K., Abraham, J., Mizuno, N., Botto, S., Sali, T. M., Broeckel, R., Haese, N., Nilsen, A., Placzek, A., Morrison, T., Heise, M., Streblow, D. & De Filippis, V., Mar 1 2018, In : Journal of Virology. 92, 6, e01913-17.

Research output: Contribution to journalArticle

Alphavirus
interferons
Interferons
agonists
Interferon Type I

Endochin-like quinolones exhibit promising efficacy against neospora caninum in vitro and in experimentally infected pregnant mice

Anghel, N., Balmer, V., Müller, J., Winzer, P., Aguado-Martinez, A., Roozbehani, M., Pou, S., Nilsen, A., Riscoe, M., Doggett, J. & Hemphill, A., Nov 19 2018, In : Frontiers in Veterinary Science. 5, NOV, 285.

Research output: Contribution to journalArticle

Neospora
quinolones
Neospora caninum
Quinolones
mice
2 Citations (Scopus)

Glucose Transporters and Virulence in Leishmania mexicana

Feng, X., Tran, K. D., Sanchez, M., Al Mezewghi, H. & Landfear, S., Aug 1 2018, In : mSphere. 3, 4

Research output: Contribution to journalArticle

Leishmania mexicana
Facilitative Glucose Transport Proteins
Virulence
Macrophages
Parasites
4 Citations (Scopus)

HOIL1 Is Essential for the Induction of Type I and III Interferons by MDA5 and Regulates Persistent Murine Norovirus Infection

MacDuff, D. A., Baldridge, M. T., Qaqish, A. M., Nice, T., Darbandi, A. D., Hartley, V. L., Peterson, S. T., Miner, J. J., Iwai, K. & Virgin, H. W., Dec 1 2018, In : Journal of Virology. 92, 23

Research output: Contribution to journalArticle

Norovirus
Interferon Type I
heme
interferons
Ligases
1 Citation (Scopus)

Kinesin-1 Proteins KIF5A, -5B, and -5C promote anterograde transport of herpes simplex virus enveloped virions in axons

DuRaine, G., Wisner, T. W., Howard, P. & Johnson, D., Oct 1 2018, In : Journal of Virology. 92, 20, e01269.

Research output: Contribution to journalArticle

herpes simplex
Kinesin
kinesin
Simplexvirus
virion
6 Citations (Scopus)

Leishmania mexicana can utilize amino acids as major carbon sources in macrophages but not in animal models

Saunders, E. C., Naderer, T., Chambers, J., Landfear, S. & Mcconville, M. J., Jan 1 2018, (Accepted/In press) In : Molecular Microbiology.

Research output: Contribution to journalArticle

Leishmania mexicana
Carbon
Animal Models
Macrophages
Amino Acids
1 Citation (Scopus)

Lipid biosensor interactions with wild type and matrix deletion HIV-1 Gag proteins

Barklis, E., Staubus, A. O., Mack, A., Harper, L., Barklis, R. L. & Alfadhli, A., May 1 2018, In : Virology. 518, p. 264-271 8 p.

Research output: Contribution to journalArticle

gag Gene Products
Biosensing Techniques
HIV-1
Lipids
Viral Proteins
5 Citations (Scopus)

Lipids and pathogenic flaviviruses: An intimate union

Leier, H. C., Messer, W. & Tafesse, F., May 1 2018, In : PLoS Pathogens. 14, 5, e1006952.

Research output: Contribution to journalArticle

Flavivirus
Lipids
9 Citations (Scopus)

MR1 displays the microbial metabolome driving selective MR1-restricted T cell receptor usage

Harriff, M., McMurtrey, C., Froyd, C. A., Jin, H., Cansler, M., Null, M., Worley, A., Meermeier, E. W., Swarbrick, G., Nilsen, A., Lewinsohn, D., Hildebrand, W., Adams, E. J. & Lewinsohn, D., Jul 13 2018, In : Science immunology. 3, 25

Research output: Contribution to journalArticle

Metabolome
T-Cell Antigen Receptor
Ligands
Mycobacterium smegmatis
T-Lymphocyte Subsets

Non-proteolytic activity of 19S proteasome subunit RPT-6 regulates GATA transcription during response to infection

Olaitan, A. O. & Aballay, A., Sep 1 2018, In : PLoS Genetics. 14, 9, e1007693.

Research output: Contribution to journalArticle

proteasome endopeptidase complex
Proteasome Endopeptidase Complex
transcription (genetics)
Infection
infection
5 Citations (Scopus)

Persistence of Systemic Murine Norovirus Is Maintained by Inflammatory Recruitment of Susceptible Myeloid Cells

Van Winkle, J. A., Robinson, B. A., Peters, A. M., Li, L., Nouboussi, R. V., Mack, M. & Nice, T., Nov 14 2018, In : Cell host & microbe. 24, 5, p. 665-676 12 p.

Research output: Contribution to journalArticle

Norovirus
Myeloid Cells
Capsid
Monocytes
Neutrophils
5 Citations (Scopus)

Pervasive tertiary structure in the dengue virus RNA genome

Dethoff, E. A., Boerneke, M. A., Gokhale, N. S., Muhire, B. M., Martin, D. P., Sacco, M. T., McFadden, M. J., Weinstein, J. B., Messer, W., Horner, S. M. & Weeks, K. M., Nov 6 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 45, p. 11513-11518 6 p.

Research output: Contribution to journalArticle

Dengue Virus
Genome
RNA
RNA Viruses
Untranslated RNA
2 Citations (Scopus)

Preconditioning in the Rhesus Macaque Induces a Proteomic Signature Following Cerebral Ischemia that Is Associated with Neuroprotection

Stevens, S. L., Liu, T., Bahjat, F., Petyuk, V. A., Schepmoes, A. A., Sontag, R. L., Gritsenko, M. A., Wu, C., Wang, S., Shukla, A. K., Jacobs, J. M., Smith, R. D., Rodland, K. D., Alexander West, G., Kohama, S., Glynn, C. & Stenzel-Poore, M., Jan 1 2018, (Accepted/In press) In : Translational Stroke Research.

Research output: Contribution to journalArticle

Brain Ischemia
Macaca mulatta
Proteomics
Stroke
Wounds and Injuries
1 Citation (Scopus)

Statistical detection of differentially abundant ions in mass spectrometry-based imaging experiments with complex designs

Bemis, K. A., Guo, D., Harry, A. J., Thomas, M., Lanekoff, I., Stenzel-Poore, M., Stevens, S. L., Laskin, J. & Vitek, O., Jan 1 2018, (Accepted/In press) In : International Journal of Mass Spectrometry.

Research output: Contribution to journalArticle

Mass spectrometry
mass spectroscopy
Ions
Imaging techniques
statistical analysis
1 Citation (Scopus)

Structure-activity relationships of bath salt components: substituted cathinones and benzofurans at biogenic amine transporters

Eshleman, A. J., Nagarajan, S., Wolfrum, K. M., Reed, J. F., Swanson, T. L., Nilsen, A. & Janowsky, A., Jan 1 2018, (Accepted/In press) In : Psychopharmacology.

Research output: Contribution to journalArticle

Benzofurans
Biogenic Amines
Structure-Activity Relationship
Baths
Salts
4 Citations (Scopus)

Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc1 and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis

McConnell, E. V., Bruzual, I., Pou, S., Winter, R., Dodean, R. A., Smilkstein, M. J., Krollenbrock, A., Nilsen, A., Zakharov, L. N., Riscoe, M. & Doggett, J., Jan 1 2018, (Accepted/In press) In : ACS Infectious Diseases.

Research output: Contribution to journalArticle

Qi
4-Quinolones
Electron Transport Complex III
Toxoplasmosis
Quinolones
7 Citations (Scopus)

The human cytomegalovirus trimer and pentamer promote sequential steps in entry into epithelial and endothelial cells at cell surfaces and endosomes

Liu, J., Jardetzky, T. S., Chin, A. L., Johnson, D. & Vanarsdall, A., Nov 1 2018, In : Journal of Virology. 92, 21, e01336.

Research output: Contribution to journalArticle

Human herpesvirus 5
endosomes
Endosomes
Cytomegalovirus
endothelial cells

Timed Regulation of 3BP2 Induction Is Critical for Sustaining CD8+ T Cell Expansion and Differentiation

Dimitriou, I. D., Lee, K., Akpan, I., Lind, E., Barr, V. A., Ohashi, P. S., Samelson, L. E. & Rottapel, R., Jul 31 2018, In : Cell Reports. 24, 5, p. 1123-1135 13 p.

Research output: Contribution to journalArticle

T-cells
Cell Differentiation
T-Lymphocytes
Chemical activation
Cell proliferation
28 Citations (Scopus)

Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology

Hirsch, A., Roberts, V., Grigsby, P., Haese, N., Schabel, M., Wang, X., Lo, J., Liu, Z., Kroenke, C. C., Smith, J. L., Kelleher, M., Broeckel, R., Kreklywich, C. N., Parkins, C. J., Denton, M., Smith, P., De Filippis, V., Messer, W., Nelson, J., Hennebold, J. & 12 others, Grafe, M., Colgin, L., Lewis, A., Ducore, R., Swanson, T., Legasse, A. W., Axthelm, M., MacAllister, R., Moses, A., Morgan, T., Frias, A. & Streblow, D., Dec 1 2018, In : Nature Communications. 9, 1, 263.

Research output: Contribution to journalArticle

viruses
infectious diseases
Fetal Development
Macaca mulatta
Viruses
2017
22 Citations (Scopus)

Adeno-associated virus (AAV) assembly-activating protein is not an essential requirement for capsid assembly of AAV serotypes 4, 5, and 11

Earley, L. F., Powers, J. M., Adachi, K., Baumgart, J. T., Meyer, N. L., Xie, Q., Chapman, M. & Nakai, H., 2017, In : Journal of Virology. 91, 3, e01980-16.

Research output: Contribution to journalArticle

Dependovirus
Virus Assembly
capsid
Capsid
serotypes
7 Citations (Scopus)

Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria

Frueh, L., Li, Y., Mather, M. W., Li, Q., Pou, S., Nilsen, A., Winter, R. W., Forquer, I. P., Pershing, A. M., Xie, L. H., Smilkstein, M. J., Caridha, D., Koop, D., Campbell, R. F., Sciotti, R. J., Kreishman-Deitrick, M., Kelly, J. X., Vesely, B., Vaidya, A. B. & Riscoe, M., Oct 13 2017, In : ACS Infectious Diseases. 3, 10, p. 728-735 8 p.

Research output: Contribution to journalArticle

Prodrugs
Malaria
Esters
Pharmaceutical Preparations
Plasmodium yoelii
1 Citation (Scopus)

Analysis of K-Ras interactions by biotin ligase tagging

Ritchie, C., Mack, A., Harper, L., Alfadhli, A., Stork, P., Nan, X. & Barklis, E., Jul 1 2017, In : Cancer Genomics and Proteomics. 14, 4, p. 225-239 15 p.

Research output: Contribution to journalArticle

Ligases
Biotin
ras Proteins
Cells
Prenylation
11 Citations (Scopus)

A novel agonist of the trif pathway induces a cellular state refractory to replication of Zika, Chikungunya, and dengue viruses

Pryke, K. M., Abraham, J., Sali, T. M., Gall, B. J., Archer, I., Liu, A., Bambina, S., Baird, J., Gough, M., Chakhtoura, M., Haddad, E. K., Kirby, I. T., Nilsen, A., Streblow, D., Hirsch, A., Smith, J. L. & De Filippis, V., May 1 2017, In : mBio. 8, 3, e00452-17.

Research output: Contribution to journalArticle

Chikungunya virus
Dengue Virus
Interferon Type I
Adaptive Immunity
Interferon Regulatory Factor-3
18 Citations (Scopus)

Arginase is essential for survival of Leishmania donovani promastigotes but not intracellular amastigotes

Boitz, J. M., Gilroy, C. A., Olenyik, T. D., Paradis, D., Perdeh, J., Dearman, K., Davis, M. J., Yates, P., Li, Y., Riscoe, M., Ullman, B. & Roberts, S. C., 2017, In : Infection and Immunity. 85, 1, e00554-16.

Research output: Contribution to journalArticle

Leishmania donovani
Arginase
Polyamines
Ornithine
Parasites