Organization profile

Organization profile

Research in the department is diverse, ranging for example from the study of glucose transporters in parasites to the interactions between herpes simplex virus and host cells.

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

T-Lymphocytes Medicine & Life Sciences
Cytomegalovirus Medicine & Life Sciences
Simplexvirus Medicine & Life Sciences
Muromegalovirus Medicine & Life Sciences
Virion Medicine & Life Sciences
Capsid Medicine & Life Sciences
Parasites Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Projects 1978 2021

Antimalarials
Malaria
Multiple Drug Resistance
Chloroquine
Amodiaquine
Trypanosomiasis
Trypanosoma brucei brucei
Parasites
Flagella
Proteins
gag Gene Products
Human Immunodeficiency Virus Proteins
HIV-1
Human Immunodeficiency Virus gag Gene Products
Virion

Research Output 1969 2019

Central memory CD8+ T cells become CD69+ tissue-residents during viral skin infection independent of CD62L-mediated lymph node surveillance

Osborn, J. F., Hobbs, S. J., Mooster, J. L., Khan, T. N., Kilgore, A. M., Harbour, J. C. & Nolz, J., Mar 1 2019, In : PLoS pathogens. 15, 3, p. e1007633

Research output: Contribution to journalArticle

Open Access
Virus Diseases
Lymph Nodes
T-Lymphocytes
Skin
Immunity

Ceramides bind VDAC2 to trigger mitochondrial apoptosis

Dadsena, S., Bockelmann, S., Mina, J. G. M., Hassan, D. G., Korneev, S., Razzera, G., Jahn, H., Niekamp, P., Müller, D., Schneider, M., Tafesse, F., Marrink, S. J., Melo, M. N. & Holthuis, J. C. M., Dec 1 2019, In : Nature communications. 10, 1, 1832.

Research output: Contribution to journalArticle

Open Access
Ceramides
apoptosis
glutamates
actuators
Apoptosis

Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms

Zhang, H., Savage, S., Schultz, A. R., Bottomly, D., White, L., Segerdell, E., Wilmot, B., McWeeney, S., Eide, C. A., Nechiporuk, T., Carlos, A., Henson, R., Lin, C., Searles, R., Ho, H., Lam, Y. L., Sweat, R., Follit, C., Jain, V., Lind, E. & 10 othersBorthakur, G., Garcia-Manero, G., Ravandi, F., Kantarjian, H. M., Cortes, J., Collins, R., Buelow, D. R., Baker, S. D., Druker, B. & Tyner, J., Dec 1 2019, In : Nature Communications. 10, 1, 244.

Research output: Contribution to journalArticle

leukemias
mutations
Acute Myeloid Leukemia
Mutation
inhibitors