Projects per year
Organization profile
Organization profile
The Molecular and Medical Genetics (MMG) Department is an interdisciplinary group of faculty performing basic laboratory research, clinical research, teaching of both graduate and medical students, overseeing the operation of several clinical labs and providing expertise in the area of clinical genetics care.
Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit
Mutation
Medicine & Life Sciences
Pantothenate Kinase-Associated Neurodegeneration
Medicine & Life Sciences
Genes
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Fanconi Anemia
Medicine & Life Sciences
DNA Mismatch Repair
Medicine & Life Sciences
Genome
Medicine & Life Sciences
Phenylketonurias
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Profiles
Projects 1976 2021
Role of Fatty Acid Oxidation Defects in Insulin Sensitivity
4/27/15 → 3/31/19
Project: Research project › Research Project
Insulin Resistance
Fatty Acids
Metabolomics
Type 2 Diabetes Mellitus
Oxidoreductases
In vivo targeting of diabetes-relevant human cell types with rAAV vectors
Grompe, M., Nakai, H. & Kay, M.
9/30/14 → 6/30/19
Project: Research project › High Impact Research and Research Infrastructure Cooperative Agreement Programs—Multi-Yr Funding
Dependovirus
Capsid
MicroRNAs
Epithelium
Somatostatin-Secreting Cells
Novel therapy for monoamine neurotransmitter deficiency in PKU
9/30/12 → 5/31/21
Project: Research project › Research Project
Phenylketonurias
Neurotransmitter Agents
Serotonin
Brain
Dopamine
Research Output 1981 2019
Activation of PP2A and inhibition of mTOR synergistically reduce MYC signaling and decrease tumor growth in pancreatic ductal adenocarcinoma
Allen-Petersen, B. L., Risom, T., Feng, Z., Wang, Z., Jenny, Z. P., Thoma, M. C., Pelz, K. R., Morton, J. P., Sansom, O. J., Lopez, C., Sheppard, B., Christensen, D. J., Ohlmeyer, M., Narla, G. & Sears, R., Jan 1 2019, In : Cancer Research. 79, 1, p. 209-219 11 p.Research output: Contribution to journal › Article
Protein Phosphatase 2
Adenocarcinoma
Phosphoric Monoester Hydrolases
Phosphotransferases
Growth
Autologous Gene and Cell Therapy Provides Safe and Long-Term Curative Therapy in A Large Pig Model of Hereditary Tyrosinemia Type 1
Hickey, R. D., Nicolas, C. T., Allen, K., Mao, S., Elgilani, F., Glorioso, J., Amiot, B., VanLith, C., Guthman, R., Du, Z., Chen, H., Harding, C., Kaiser, R. A., Nyberg, S. L. & Lillegard, J. B., Jan 1 2019, In : Cell Transplantation. 28, 1, p. 79-88 10 p.Research output: Contribution to journal › Article
Tyrosinemias
Cell- and Tissue-Based Therapy
Genetic Therapy
Liver
Hydrolases
Erratum to: Interplay between hypoxia and androgen controls a metabolic switch conferring resistance to androgen/AR-targeted therapy (Nature Communications, (2018), 9, 1, (4972), 10.1038/s41467-018-07411-7)
Geng, H., Xue, C., Mendonca, J., Sun, X-X., Liu, Q., Reardon, P. N., Chen, Y., Qian, K., Hua, V., Chen, A., Pan, F., Yuan, J., Dang, S., Beer, T. T., Dai, M., Kachhap, S. K. & Qian, Z. D., Dec 1 2019, In : Nature communications. 10, 1, 164.Research output: Contribution to journal › Comment/debate
hypoxia
Androgens
therapy
switches
communication