Division of Bioinformatics and Computational Biology

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Genes Medicine & Life Sciences
Transcriptome Medicine & Life Sciences
Gene Regulatory Networks Medicine & Life Sciences
Gene Expression Medicine & Life Sciences
Acute Myeloid Leukemia Medicine & Life Sciences
Virus Diseases Medicine & Life Sciences
Quantitative Trait Loci Medicine & Life Sciences
Brain Medicine & Life Sciences

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Projects 1995 2020

GENETICS OF NEUROADAPTATION TO ETHANOL

Mitchell, S., Hitzemann, R., Grant, K. (., Cunningham, C., Finn, D. (., Klein, R., Belknap, J., Ryabinin, A., Buck, K., Wiren, K., Crabbe, J. J., Phillips, T., Rutledge-Gorman, M., Crawshaw, L., Stackman, R. W., McWeeney, S., Nagel, B. & Risinger, F.

National Institutes of Health

12/20/9512/31/20

Project: Research project

Ethanol
Alcohols
Impulsive Behavior
Genomics
Genes

OREGON CANCER CENTER

Mori, M. (., Corless, C., Beer, T. (., McWeeney, S., Harrington, C. (., Bagby, G., Druker, B., Sexton, G., Hall, A., Henner, W., Samuels, M. H., Bakke, A., Hoatlin, M., Baetscher, M., Keller, T., Nagalla, S., Magun, B. E., Koop, D. R., Mauro, M. J., Blanke, C. D., Bakke, A., Baetscher, M., Koop, D., Spellman, P., David, L., Coussens, L., Streeter, P., Thomas, G., Mori, M. (., Mori, M. (., Harrington, C. (., Bergan, R. & Blanke, C.

National Institutes of Health

8/1/976/30/17

Project: Research project

Neoplasms
Research
Research Personnel
Biostatistics
Translational Medical Research

Research Output 2010 2019

Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms

Zhang, H., Savage, S., Schultz, A. R., Bottomly, D., White, L., Segerdell, E., Wilmot, B., McWeeney, S., Eide, C. A., Nechiporuk, T., Carlos, A., Henson, R., Lin, C., Searles, R., Ho, H., Lam, Y. L., Sweat, R., Follit, C., Jain, V., Lind, E. & 10 othersBorthakur, G., Garcia-Manero, G., Ravandi, F., Kantarjian, H. M., Cortes, J., Collins, R., Buelow, D. R., Baker, S. D., Druker, B. & Tyner, J., Dec 1 2019, In : Nature Communications. 10, 1, 244.

Research output: Contribution to journalArticle

leukemias
mutations
Acute Myeloid Leukemia
Mutation
inhibitors
2 Citations (Scopus)

CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells

Edwards, D. K., Watanabe-Smith, K., Rofelty, A., Damnernsawad, A., Laderas, T., Lamble, A., Lind, E., Kaempf, A., Mori, M. T., Rosenberg, M., d’Almeida, A., Long, N., Agarwal, A., Sweeney, D. T., Loriaux, M., McWeeney, S. & Tyner, J., Feb 7 2019, In : Blood. 133, 6, p. 588-599 12 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Acute Myeloid Leukemia
Macrophage Colony-Stimulating Factor
Cytokines
Cells
1 Citation (Scopus)

Predicting response to BET inhibitors using computational modeling: A BEAT AML project study

Drusbosky, L. M., Vidva, R., Gera, S., Lakshminarayana, A. V., Shyamasundar, V. P., Agrawal, A. K., Talawdekar, A., Abbasi, T., Vali, S., Tognon, C. E., Kurtz, S. E., Tyner, J., McWeeney, S., Druker, B. & Cogle, C. R., Feb 1 2019, In : Leukemia Research. 77, p. 42-50 9 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Genomics
Computational Biology
MAP Kinase Signaling System
Chromosome Aberrations