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Inferring causal molecular networks: Empirical assessment through a community-based effort

Hill, S. M., Heiser, L. M., Cokelaer, T., Linger, M., Nesser, N. K., Carlin, D. E., Zhang, Y., Sokolov, A., Paull, E. O., Wong, C. K., Graim, K., Bivol, A., Wang, H., Zhu, F., Afsari, B., Danilova, L. V., Favorov, A. V., Lee, W. S., Taylor, D., Hu, C. W. & 115 others, Long, B. L., Noren, D. P., Bisberg, A. J., Mills, G. B., Gray, J. W., Kellen, M., Norman, T., Friend, S., Qutub, A. A., Fertig, E. J., Guan, Y., Song, M., Stuart, J. M., Spellman, P. T., Koeppl, H., Stolovitzky, G., Saez-Rodriguez, J., Mukherjee, S., Al-Ouran, R., Anton, B., Arodz, T., Sichani, O. A., Bagheri, N., Berlow, N., Bohler, A., Bonet, J., Bonneau, R., Budak, G., Bunescu, R., Caglar, M., Cai, B., Cai, C., Carlon, A., Chen, L., Ciaccio, M. F., Cooper, G., Coort, S., Creighton, C. J., Daneshmand, S. M. H., De La Fuente, A., Di Camillo, B., Dutta-Moscato, J., Emmett, K., Evelo, C., Fassia, M. K. H., Finotello, F., Finkle, J. D., Gao, X., Garcia-Garcia, J., Ghosh, S., Giaretta, A., Großeholz, R., Guinney, J., Hafemeister, C., Hahn, O., Haider, S., Hase, T., Hodgson, J., Hoff, B., Hsu, C. H., Hu, Y., Huang, X., Jalili, M., Jiang, X., Kacprowski, T., Kaderali, L., Kang, M., Kannan, V., Kikuchi, K., Kim, D. C., Kitano, H., Knapp, B., Komatsoulis, G., Krämer, A., Kursa, M. B., Kutmon, M., Li, Y., Liang, X., Liu, Z., Liu, Y., Lu, S., Lu, X., Manfrini, M., Matos, M. R. A., Meerzaman, D., Min, W., Müller, C. L., Neapolitan, R. E., Oliva, B., Opiyo, S. O., Pal, R., Palinkas, A., Planas-Iglesias, J., Poglayen, D., Sambo, F., Sanavia, T., Sharifi-Zarchi, A., Slawek, J., Streck, A., Strunz, S., Tegnér, J., Thobe, K., Toffolo, G. M., Trifoglio, E., Unger, M., Wan, Q., Welch, L., Wu, J. J., Xue, A. Y., Yamanaka, R., Yan, C., Zairis, S., Zengerling, M., Zenil, H. & Zi, Z., Mar 30 2016, In : Nature Methods. 13, 4, p. 310-322 13 p.

Research output: Contribution to journalArticle

104 Scopus citations

Integrated analysis of breast cancer cell lines reveals unique signaling pathways

Heiser, L. M., Wang, N. J., Talcott, C. L., Laderoute, K. R., Knapp, M., Guan, Y., Hu, Z., Ziyad, S., Weber, B. L., Laquerre, S., Jackson, J. R., Wooster, R. F., Kuo, W., Gray, J. W. & Spellman, P. T., Mar 25 2009, In : Genome biology. 10, 3, R31.

Research output: Contribution to journalArticle

51 Scopus citations

Integrated genomic analyses of ovarian carcinoma

Bell, D., Berchuck, A., Birrer, M., Chien, J., Cramer, D. W., Dao, F., Dhir, R., Disaia, P., Gabra, H., Glenn, P., Godwin, A. K., Gross, J., Hartmann, L., Huang, M., Huntsman, D. G., Iacocca, M., Imielinski, M., Kalloger, S., Karlan, B. Y., Levine, D. A. & 240 others, Mills, G. B., Morrison, C., Mutch, D., Olvera, N., Orsulic, S., Park, K., Petrelli, N., Rabeno, B., Rader, J. S., Sikic, B. I., Smith-Mccune, K., Sood, A. K., Bowtell, D., Penny, R., Testa, J. R., Chang, K., Dinh, H. H., Drummond, J. A., Fowler, G., Gunaratne, P., Hawes, A. C., Kovar, C. L., Lewis, L. R., Morgan, M. B., Newsham, I. F., Santibanez, J., Reid, J. G., Trevino, L. R., Wu, Y. Q., Wang, M., Muzny, D. M., Wheeler, D. A., Gibbs, R. A., Getz, G., Lawrence, M. S., Cibulskis, K., Sivachenko, A. Y., Sougnez, C., Voet, D., Wilkinson, J., Bloom, T., Ardlie, K., Fennell, T., Baldwin, J., Gabriel, S., Lander, E. S., Ding, L., Fulton, R. S., Koboldt, D. C., McLellan, M. D., Wylie, T., Walker, J., O'Laughlin, M., Dooling, D. J., Fulton, L., Abbott, R., Dees, N. D., Zhang, Q., Kandoth, C., Wendl, M., Schierding, W., Shen, D., Harris, C. C., Schmidt, H., Kalicki, J., Delehaunty, K. D., Fronick, C. C., Demeter, R., Cook, L., Wallis, J. W., Lin, L., Magrini, V. J., Hodges, J. S., Eldred, J. M., Smith, S. M., Pohl, C. S., Vandin, F., Raphael, B. J., Weinstock, G. M., Mardis, E. R., Wilson, R. K., Meyerson, M., Winckler, W., Verhaak, R. G. W., Carter, S. L., Mermel, C. H., Saksena, G., Nguyen, H., Onofrio, R. C., Hubbard, D., Gupta, S., Crenshaw, A., Ramos, A. H., Chin, L., Protopopov, A., Zhang, J., Kim, T. M., Perna, I., Xiao, Y., Zhang, H., Ren, G., Sathiamoorthy, N., Park, R. W., Lee, E., Park, P. J., Kucherlapati, R., Absher, D. M., Waite, L., Sherlock, G., Brooks, J. D., Li, J. Z., Xu, J., Myers, R. M., Laird, P. W., Cope, L., Herman, J. G., Shen, H., Weisenberger, D. J., Noushmehr, H., Pan, F., Triche, T., Berman, B. P., Van Den Berg, D. J., Buckley, J., Baylin, S. B., Spellman, P. T., Purdom, E., Neuvial, P., Bengtsson, H., Jakkula, L. R., Durinck, S., Han, J., Dorton, S., Marr, H., Choi, Y. G., Wang, V., Wang, N. J., Ngai, J., Conboy, J. G., Parvin, B., Feiler, H. S., Speed, T. P., Gray, J. W., Socci, N. D., Liang, Y., Taylor, B. S., Schultz, N., Borsu, L., Lash, A. E., Brennan, C., Viale, A., Sander, C., Ladanyi, M., Hoadley, K. A., Meng, S., Du, Y., Shi, Y., Li, L., Turman, Y. J., Zang, D., Helms, E. B., Balu, S., Zhou, X., Wu, J., Topal, M. D., Hayes, D. N., Perou, C. M., Wu, C. J., Shukla, S., Sivachenko, A., Jing, R., Liu, Y., Noble, M., Carter, H., Kim, D., Karchin, R., Korkola, J. E., Heiser, L. M., Cho, R. J., Hu, Z., Cerami, E., Olshen, A., Reva, B., Antipin, Y., Shen, R., Mankoo, P., Sheridan, R., Ciriello, G., Chang, W. K., Bernanke, J. A., Haussler, D., Benz, C. C., Stuart, J. M., Benz, S. C., Sanborn, J. Z., Vaske, C. J., Zhu, J., Szeto, C., Scott, G. K., Yau, C., Wilkerson, M. D., Zhang, N., Akbani, R., Baggerly, K. A., Yung, W. K., Weinstein, J. N., Shelton, T., Grimm, D., Hatfield, M., Morris, S., Yena, P., Rhodes, P., Sherman, M., Paulauskis, J., Millis, S., Kahn, A., Greene, J. M., Sfeir, R., Jensen, M. A., Chen, J., Whitmore, J., Alonso, S., Jordan, J., Chu, A., Barker, A., Compton, C., Eley, G., Ferguson, M., Fielding, P., Gerhard, D. S., Myles, R., Schaefer, C., Mills Shaw, K. R., Vaught, J., Vockley, J. B., Good, P. J., Guyer, M. S., Ozenberger, B., Peterson, J. & Thomson, E., Jun 30 2011, In : Nature. 474, 7353, p. 609-615 7 p.

Research output: Contribution to journalArticle

3965 Scopus citations

Integrative molecular network analysis identifies emergent enzalutamide resistance mechanisms in prostate cancer

King, C. J., Woodward, J., Schwartzman, J., Coleman, D. J., Lisac, R., Wang, N., Hook, K. V., Gao, L., Urrutia, J., Dane, M. A., Heiser, L. M. & Alumkal, J. J., 2017, In : Oncotarget. 8, 67, p. 111084-111095 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Intracellular imaging of HCV RNA and cellular lipids by using simultaneous two-photon fluorescence and coherent anti-stokes Raman scattering microscopies

Nan, X., Tonary, A. M., Stolow, A., Xie, X. S. & Pezacki, J. P., Dec 1 2006, In : ChemBioChem. 7, 12, p. 1895-1897 3 p.

Research output: Contribution to journalArticle

59 Scopus citations

Large-scale drug screens support precision medicine

Gray, J. W. & Mills, G. B., Nov 2015, In : Cancer discovery. 5, 11, p. 1130-1132 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

LSD1 activates a lethal prostate cancer gene network independently of its demethylase function

Sehrawat, A., Gao, L., Wang, Y., Bankhead, A., McWeeney, S. K., King, C. J., Schwartzman, J., Urrutia, J., Bisson, W. H., Coleman, D. J., Joshi, S. K., Kim, D. H., Sampson, D. A., Weinmann, S., Kallakury, B. V. S., Berry, D. L., Haque, R., Van Den Eeden, S. K., Sharma, S., Bearss, J. & 4 others, Beer, T. M., Thomas, G. V., Heiser, L. M. & Alumkal, J. J., May 1 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 18, p. E4179-E4188

Research output: Contribution to journalArticle

42 Scopus citations

Maintenance of MYC expression promotes de novo resistance to BET bromodomain inhibition in castration-resistant prostate cancer

Coleman, D. J., Gao, L., Schwartzman, J., Korkola, J. E., Sampson, D., Derrick, D. S., Urrutia, J., Balter, A., Burchard, J., King, C. J., Chiotti, K. E., Heiser, L. M. & Alumkal, J. J., Dec 1 2019, In : Scientific Reports. 9, 1, 3823.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Methodology for quantitative characterization of fluorophore photoswitching to predict superresolution microscopy image quality

Bittel, A. M., Nickerson, A., Saldivar, I. S., Dolman, N. J., Nan, X. & Gibbs, S., Jul 14 2016, In : Scientific Reports. 6, 29687.

Research output: Contribution to journalArticle

9 Scopus citations

Metrics other than potency reveal systematic variation in responses to cancer drugs

Fallahi-Sichani, M., Honarnejad, S., Heiser, L. M., Gray, J. W. & Sorger, P. K., Nov 1 2013, In : Nature Chemical Biology. 9, 11, p. 708-714 7 p.

Research output: Contribution to journalArticle

159 Scopus citations

Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes

Watson, S. S., Dane, M., Chin, K-Y., Tatarova, Z., Liu, M., Liby, T., Thompson, W., Smith, R., Nederlof, M., Bucher, E., Kilburn, D., Whitman, M., Sudar, D., Mills, G., Heiser, L., Jonas, O., Gray, J. & Korkola, J., Jan 1 2018, (Accepted/In press) In : Cell Systems.

Research output: Contribution to journalArticle

13 Scopus citations

Modeling precision treatment of breast cancer

Daemen, A., Griffith, O. L., Heiser, L. M., Wang, N. J., Enache, O. M., Sanborn, Z., Pepin, F., Durinck, S., Korkola, J. E., Griffith, M., Hur, J. S., Huh, N., Chung, J., Cope, L., Fackler, M. J., Umbricht, C., Sukumar, S., Seth, P., Sukhatme, V. P., Jakkula, L. R. & 7 others, Lu, Y., Mills, G. B., Cho, R. J., Collisson, E. A., van't Veer, L. J., Spellman, P. T. & Gray, J. W., Dec 10 2013, In : Genome biology. 14, 10, R110.

Research output: Contribution to journalArticle

Open Access
141 Scopus citations

MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance

Farrell, A. S., Joly, M. M., Allen-Petersen, B. L., Worth, P. J., Lanciault, C., Sauer, D., Link, J., Pelz, C., Heiser, L. M., Morton, J. P., Muthalagu, N., Hoffman, M. T., Manning, S. L., Pratt, E. D., Kendsersky, N. D., Egbukichi, N., Amery, T. S., Thoma, M. C., Jenny, Z. P., Rhim, A. D. & 5 others, Murphy, D. J., Sansom, O. J., Crawford, H. C., Sheppard, B. C. & Sears, R. C., Dec 1 2017, In : Nature communications. 8, 1, 1728.

Research output: Contribution to journalArticle

21 Scopus citations

Myeloid-Derived Suppressor Cell Membrane-Coated Magnetic Nanoparticles for Cancer Theranostics by Inducing Macrophage Polarization and Synergizing Immunogenic Cell Death

Yu, G. T., Rao, L., Wu, H., Yang, L. L., Bu, L. L., Deng, W. W., Wu, L., Nan, X., Zhang, W. F., Zhao, X. Z., Liu, W. & Sun, Z. J., Sep 12 2018, In : Advanced Functional Materials. 28, 37, 1801389.

Research output: Contribution to journalArticle

35 Scopus citations

Near-infrared nerve-binding fluorophores for buried nerve tissue imaging

Wang, L. G., Barth, C. W., Kitts, C. H., Mebrat, M. D., Montaño, A. R., House, B. J., McCoy, M. E., Antaris, A. L., Galvis, S. N., McDowall, I., Sorger, J. M. & Gibbs, S. L., May 6 2020, In : Science translational medicine. 12, 542

Research output: Contribution to journalArticle

Nile Red derivatives enable improved ratiometric imaging for nerve-specific contrast

Korber, J. R., Barth, C. W. & Gibbs, S., Jul 1 2018, In : Journal of Biomedical Optics. 23, 7, 076002.

Research output: Contribution to journalArticle

3 Scopus citations

Nonperturbative chemical imaging of organelle transport in living cells with coherent anti-Stokes Raman scattering microscopy

Nan, X., Potma, E. O. & Xie, X. S., 2006, In : Biophysical Journal. 91, 2, p. 728-735 8 p.

Research output: Contribution to journalArticle

178 Scopus citations

Observation of individual microtubule motor steps in living cells with endocytosed quantum dots

Nan, X., Sims, P. A., Chen, P. & Sunney Xie, X., Dec 29 2005, In : Journal of Physical Chemistry B. 109, 51, p. 24220-24224 5 p.

Research output: Contribution to journalArticle

144 Scopus citations

Oligonucleotide conjugated antibodies permit highly multiplexed immunofluorescence for future use in clinical histopathology

Mcmahon, N. P., Jones, J. A., Kwon, S., Chin, K., Nederlof, M. A., Gray, J. W. & Gibbs, S. L., May 1 2020, In : Journal of biomedical optics. 25, 5, 056004.

Research output: Contribution to journalArticle

Open Access

Optimizing fresh specimen staining for rapid identification of tumor biomarkers during surgery

Barth, C. W., Schaefer, J. M., Rossi, V. M., Davis, S. C. & Gibbs, S. L., 2017, In : Theranostics. 7, 19, p. 4722-4734 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Organelle tracking in a living cell with microsecond time resolution and nanometer spatial precision

Nan, X., Sims, P. A. & Xie, X. S., Apr 4 2008, In : ChemPhysChem. 9, 5, p. 707-712 6 p.

Research output: Contribution to journalArticle

121 Scopus citations

Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase

Fu, X., Creighton, C. J., Biswal, N. C., Kumar, V., Shea, M., Herrera, S., Contreras, A., Gutierrez, C., Wang, T., Nanda, S., Giuliano, M., Morrison, G., Nardone, A., Karlin, K. L., Westbrook, T. F., Heiser, L. M., Anur, P., Spellman, P., Guichard, S. M., Smith, P. D. & 10 others, Davies, B. R., Klinowska, T., Lee, A. V., Mills, G. B., Rimawi, M. F., Hilsenbeck, S. G., Gray, J. W., Joshi, A., Osborne, C. K. & Schiff, R., Sep 11 2014, In : Breast Cancer Research. 16, 5, 430.

Research output: Contribution to journalArticle

47 Scopus citations

p21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils

Itakura, A., Aslan, J. E., Kusanto, B. T., Phillips, K. G., Porter, J. E., Newton, P. K., Nan, X., Insall, R. H., Chernoff, J. & McCarty, O. J. T., Sep 3 2013, In : PloS one. 8, 9, e73063.

Research output: Contribution to journalArticle

26 Scopus citations

Pathway-enriched gene signature associated with 53BP1 response to PARP inhibition in triple-negative breast cancer

Hassan, S., Esch, A., Liby, T., Gray, J. & Heiser, L., Dec 1 2017, In : Molecular Cancer Therapeutics. 16, 12, p. 2892-2901 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Patterned Assembly of Shortened Single-Walled Carbon Nanotubes on Gold Surface

Nan, X. L., Zhang, J., Liu, Z. F., Shi, Z. J. & Gu, Z. N., Dec 1 2001, In : Acta Physico - Chimica Sinica. 17, 5, p. 393-396 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder

Brown, A., Patel, S., Ward, C., Lorenz, A., Ortiz, M., DuRoss, A., Wieghardt, F., Esch, A., Otten, E. G., Heiser, L. M., Korolchuk, V. I., Sun, C., Sarkar, S. & Sahay, G., Aug 30 2016, In : Scientific Reports. 6, 31750.

Research output: Contribution to journalArticle

14 Scopus citations

Peroxisome proliferator-activated receptor α antagonism inhibits hepatitis C virus replication

Rakic, B., Sagan, S. M., Noestheden, M., Bélanger, S., Nan, X., Evans, C. L., Xie, X. S. & Pezacki, J. P., Jan 1 2006, In : Chemistry and Biology. 13, 1, p. 23-30 8 p.

Research output: Contribution to journalArticle

68 Scopus citations

Photoactivated localization microscopy with bimolecular fluorescence complementation (Bifc-palm)

Nickerson, A., Huang, T., Lin, L. J. & Nan, X., Dec 22 2015, In : Journal of Visualized Experiments. 2015, 106, e53154.

Research output: Contribution to journalArticle

3 Scopus citations

Photoactivated localization microscopy with Bimolecular Fluorescence Complementation (BiFC-PALM) for nanoscale imaging of protein-protein interactions in cells

Nickerson, A., Huang, T., Lin, L. J. & Nan, X., Jun 25 2014, In : PloS one. 9, 6, e100589.

Research output: Contribution to journalArticle

45 Scopus citations

Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination

Sanborn, J. Z., Chung, J., Purdom, E., Wang, N. J., Kakavand, H., Wilmott, J. S., Butler, T., Thompson, J. F., Mann, G. J., Haydu, L. E., Saw, R. P. M., Busam, K. J., Lo, R. S., Collisson, E. A., Hur, J. S., Spellman, P. T., Cleaver, J. E., Gray, J. W., Huh, N., Murali, R. & 3 others, Scolyer, R. A., Bastian, B. C. & Cho, R. J., Sep 1 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 35, p. 10995-11000 6 p.

Research output: Contribution to journalArticle

67 Scopus citations

Polymeric Micelles as Carriers for Nerve-Highlighting Fluorescent Probe Delivery

Hackman, K. M., Doddapaneni, B. S., Barth, C. W., Wierzbicki, I. H., Alani, A. W. G. & Gibbs, S. L., Oct 20 2015, In : Molecular Pharmaceutics. 12, 12, p. 4386-4394 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Post-translational modification localizes MYC to the nuclear pore basket to regulate a subset of target genes involved in cellular responses to environmental signals

Su, Y., Pelz, C., Huang, T., Torkenczy, K., Wang, X., Cherry, A., Daniel, C. J., Liang, J., Nan, X., Dai, M., Adey, A., Impey, S. & Sears, R., Nov 1 2018, In : Genes & development. 32, 21-22, p. 1398-1419 22 p.

Research output: Contribution to journalArticle

19 Scopus citations

Quantification of fluorophore distribution and therapeutic response in matched in vivo and ex vivo pancreatic cancer model systems

Solanki, A., King, D., Thibault, G., Wang, L. & Gibbs, S. L., 2020, In : PloS one. 15, 2, e0229407.

Research output: Contribution to journalArticle

Open Access

Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics

Hafner, M., Heiser, L., Williams, E. H., Niepel, M., Wang, N. J., Korkola, J., Gray, J. & Sorger, P. K., Nov 7 2017, In : Scientific data. 4, 170166.

Research output: Contribution to journalArticle

10 Scopus citations

Quantitating morphological changes in biological samples during scanning electron microscopy sample preparation with correlative super-resolution microscopy

Zhang, Y., Huang, T., Jorgens, D. M., Nickerson, A., Lin, L. J., Pelz, J., Gray, J. W., López, C. S. & Nan, X., May 2017, In : PloS one. 12, 5, e0176839.

Research output: Contribution to journalArticle

17 Scopus citations

Ras dimer formation as a new signaling mechanism and potential cancer therapeutic target

Chen, M., Peters, A., Huang, T. & Nan, X., Mar 1 2016, In : Mini-Reviews in Medicinal Chemistry. 16, 5, p. 391-403 13 p.

Research output: Contribution to journalArticle

23 Scopus citations

Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway

Nan, X., Tamgüney, T. M., Collisson, E. A., Lin, L. J., Pitt, C., Galeas, J., Lewis, S., Gray, J. W., McCormick, F. & Chu, S., Jun 30 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 26, p. 7996-8001 6 p.

Research output: Contribution to journalArticle

122 Scopus citations

Simultaneous Multicolor Single-Molecule Tracking with Single-Laser Excitation via Spectral Imaging

Huang, T., Phelps, C., Wang, J., Lin, L. J., Bittel, A., Scott, Z., Jacques, S., Gibbs, S., Gray, J. & Nan, X., Jan 23 2018, In : Biophysical Journal. 114, 2, p. 301-310 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling

Nan, X., Collisson, E. A., Lewis, S., Huang, J., Tamgüney, T. M., Liphardt, J. T., McCormick, F., Gray, J. W. & Chu, S., Nov 12 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 46, p. 18519-18524 6 p.

Research output: Contribution to journalArticle

91 Scopus citations

Spatial updating in area LIP is independent of saccade direction

Heiser, L. M. & Colby, C. L., May 1 2006, In : Journal of neurophysiology. 95, 5, p. 2751-2767 17 p.

Research output: Contribution to journalArticle

65 Scopus citations

Src and STAT3 inhibitors synergize to promote tumor inhibition in renal cell carcinoma

Lue, H. W., Cole, B., Rao, S. A. M., Podolak, J., Van Gaest, A., King, C., Eide, C. A., Wilmot, B., Xue, C., Spellman, P. T., Heiser, L. M., Tyner, J. W. & Thomas, G. V., 2015, In : Oncotarget. 6, 42, p. 44675-44687 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Structure-Activity Relationship of Nerve-Highlighting Fluorophores

Gibbs, S. L., Xie, Y., Goodwill, H. L., Nasr, K. A., Ashitate, Y., Madigan, V. J., Siclovan, T. M., Zavodszky, M., Tan Hehir, C. A. & Frangioni, J. V., Sep 9 2013, In : PloS one. 8, 9, e73493.

Research output: Contribution to journalArticle

21 Scopus citations
1 Scopus citations

Subtype and pathway specific responses to anticancer compounds in breast cancer

Heiser, L. M., Sadanandam, A., Kuo, W. L., Benz, S. C., Goldstein, T. C., Ng, S., Gibb, W. J., Wang, N. J., Ziyad, S., Tong, F., Bayani, N., Hu, Z., Billig, J. I., Dueregger, A., Lewis, S., Jakkula, L., Korkola, J. E., Durinck, S., Pepin, F., Guan, Y. & 23 others, Purdom, E., Neuvial, P., Bengtsson, H., Wood, K. W., Smith, P. G., Vassilev, L. T., Hennessy, B. T., Greshock, J., Bachman, K. E., Hardwicke, M. A., Park, J. W., Marton, L. J., Wolf, D. M., Collisson, E. A., Neve, R. M., Mills, G. B., Speed, T. P., Feiler, H. S., Richard, F. W., Haussler, D., Stuart, J. M., Gray, J. W. & Spellman, P. T., Feb 21 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 8, p. 2724-2729 6 p.

Research output: Contribution to journalArticle

275 Scopus citations

Superresolution imaging of clinical formalin fixed paraffin embedded breast cancer with single molecule localization microscopy

Creech, M. K., Wang, J., Nan, X. & Gibbs, S., Jan 18 2017, In : Scientific Reports. 7, 40766.

Research output: Contribution to journalArticle

14 Scopus citations

Superresolution microscopy with novel BODIPY-based fluorophores

Bittel, A. M., Saldivar, I. S., Dolman, N. J., Nan, X. & Gibbs, S. L., Oct 2018, In : PloS one. 13, 10, e0206104.

Research output: Contribution to journalArticle

4 Scopus citations

Targeting the mevalonate pathway to overcome acquired anti-HER2 treatment resistance in breast cancer

Sethunath, V., Hu, H., De Angelis, C., Veeraraghavan, J., Qin, L., Wang, N., Simon, L. M., Wang, T., Fu, X., Nardone, A., Pereira, R., Nanda, S., Griffith, O. L., Tsimelzon, A., Shaw, C., Chamness, G. C., Reis-Filho, J. S., Weigelt, B., Heiser, L. M., Hilsenbeck, S. G. & 5 others, Huang, S., Rimawi, M. F., Gray, J. W., Osborne, C. K. & Schiff, R., 2019, In : Molecular Cancer Research. 17, 11, p. 2318-2330 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

The consensus molecular subtypes of colorectal cancer

Guinney, J., Dienstmann, R., Wang, X., De Reyniès, A., Schlicker, A., Soneson, C., Marisa, L., Roepman, P., Nyamundanda, G., Angelino, P., Bot, B. M., Morris, J. S., Simon, I. M., Gerster, S., Fessler, E., De Sousa .E Melo, F., Missiaglia, E., Ramay, H., Barras, D., Homicsko, K. & 20 others, Maru, D., Manyam, G. C., Broom, B., Boige, V., Perez-Villamil, B., Laderas, T., Salazar, R., Gray, J. W., Hanahan, D., Tabernero, J., Bernards, R., Friend, S. H., Laurent-Puig, P., Medema, J. P., Sadanandam, A., Wessels, L., Delorenzi, M., Kopetz, S., Vermeulen, L. & Tejpar, S., Nov 1 2015, In : Nature medicine. 21, 11, p. 1350-1356 7 p.

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The role of coagulation and platelets in colon cancer-associated thrombosis

Mitrugno, A., Tassi Yunga, S., Sylman, J. L., Zilberman-Rudenko, J., Shirai, T., Hebert, J. F., Kayton, R., Zhang, Y., Nan, X., Shatzel, J. J., Esener, S., Duvernay, M. T., Hamm, H. E., Gruber, A., Williams, C. D., Takata, Y., Armstrong, R., Morgan, T. & McCarty, O., Feb 1 2019, In : American journal of physiology. Cell physiology. 316, 2, p. C264-C273

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10 Scopus citations

Toolbox for non-intrusive structural and functional analysis of recombinant VLP based vaccines: A case study with hepatitis B vaccine

Mulder, A. M., Carragher, B., Towne, V., Meng, Y., Wang, Y., Dieter, L., Potter, C. S., Washabaugh, M. W., Sitrin, R. D. & Zhao, Q., Apr 6 2012, In : PloS one. 7, 4, e33235.

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37 Scopus citations