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2015

Decoupling of the PI3K pathway via mutation necessitates combinatorial treatment in HER2+ breast cancer

Korkola, J. E., Collisson, E. A., Heiser, L., Oates, C., Bayani, N., Itani, S., Esch, A., Thompson, W., Griffith, O. L., Wang, N. J., Kuo, W. L., Cooper, B., Billig, J., Ziyad, S., Hung, J. L., Feiler, H., Lu, Y., Mills, G. B., Spellman, P. T., Tomlin, C. & 3 others, Mukherjee, S., Gray, J. W. & Jakkula, L., Jul 16 2015, In : PloS one. 10, 7, e0133219.

Research output: Contribution to journalArticle

11 Scopus citations

Disentangling multidimensional spatio-temporal data into their common and aberrant responses

Chang, Y. H., Korkola, J., Amin, D. N., Moasser, M. M., Carmena, J. M., Gray, J. W. & Tomlin, C. J., Apr 22 2015, In : PloS one. 10, 4, e0121607.

Research output: Contribution to journalArticle

1 Scopus citations

Exome sequencing of cell-free DNA from metastatic cancer patients identifies clinically actionable mutations distinct from primary disease

Butler, T. M., Johnson-Camacho, K., Peto, M., Wang, N. J., Macey, T. A., Korkola, J. E., Koppie, T. M., Corless, C. L., Gray, J. W. & Spellman, P. T., Aug 28 2015, In : PloS one. 10, 8, e0136407.

Research output: Contribution to journalArticle

64 Scopus citations

Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway

Shain, A. H., Garrido, M., Botton, T., Talevich, E., Yeh, I., Sanborn, J. Z., Chung, J., Wang, N. J., Kakavand, H., Mann, G. J., Thompson, J. F., Wiesner, T., Roy, R., Olshen, A. B., Gagnon, A., Gray, J. W., Huh, N., Hur, J. S., Busam, K. J., Scolyer, R. A. & 3 others, Cho, R. J., Murali, R. & Bastian, B. C., Sep 29 2015, In : Nature genetics. 47, 10, p. 1194-1199 6 p.

Research output: Contribution to journalArticle

103 Scopus citations

GATA2 regulates Wnt signaling to promote primitive red blood cell fate

Mimoto, M. S., Kwon, S., Green, Y. S., Goldman, D. & Christian, J. L., Nov 1 2015, In : Developmental Biology. 407, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Large-scale drug screens support precision medicine

Gray, J. W. & Mills, G. B., Nov 2015, In : Cancer discovery. 5, 11, p. 1130-1132 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Photoactivated localization microscopy with bimolecular fluorescence complementation (Bifc-palm)

Nickerson, A., Huang, T., Lin, L. J. & Nan, X., Dec 22 2015, In : Journal of Visualized Experiments. 2015, 106, e53154.

Research output: Contribution to journalArticle

3 Scopus citations

Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination

Sanborn, J. Z., Chung, J., Purdom, E., Wang, N. J., Kakavand, H., Wilmott, J. S., Butler, T., Thompson, J. F., Mann, G. J., Haydu, L. E., Saw, R. P. M., Busam, K. J., Lo, R. S., Collisson, E. A., Hur, J. S., Spellman, P. T., Cleaver, J. E., Gray, J. W., Huh, N., Murali, R. & 3 others, Scolyer, R. A., Bastian, B. C. & Cho, R. J., Sep 1 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 35, p. 10995-11000 6 p.

Research output: Contribution to journalArticle

66 Scopus citations

Polymeric Micelles as Carriers for Nerve-Highlighting Fluorescent Probe Delivery

Hackman, K. M., Doddapaneni, B. S., Barth, C. W., Wierzbicki, I. H., Alani, A. W. G. & Gibbs, S. L., Oct 20 2015, In : Molecular Pharmaceutics. 12, 12, p. 4386-4394 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway

Nan, X., Tamgüney, T. M., Collisson, E. A., Lin, L. J., Pitt, C., Galeas, J., Lewis, S., Gray, J. W., McCormick, F. & Chu, S., Jun 30 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 26, p. 7996-8001 6 p.

Research output: Contribution to journalArticle

120 Scopus citations

Src and STAT3 inhibitors synergize to promote tumor inhibition in renal cell carcinoma

Lue, H. W., Cole, B., Rao, S. A. M., Podolak, J., Van Gaest, A., King, C., Eide, C. A., Wilmot, B., Xue, C., Spellman, P. T., Heiser, L. M., Tyner, J. W. & Thomas, G. V., Jan 1 2015, In : Oncotarget. 6, 42, p. 44675-44687 13 p.

Research output: Contribution to journalArticle

15 Scopus citations

The consensus molecular subtypes of colorectal cancer

Guinney, J., Dienstmann, R., Wang, X., De Reyniès, A., Schlicker, A., Soneson, C., Marisa, L., Roepman, P., Nyamundanda, G., Angelino, P., Bot, B. M., Morris, J. S., Simon, I. M., Gerster, S., Fessler, E., De Sousa .E Melo, F., Missiaglia, E., Ramay, H., Barras, D., Homicsko, K. & 20 others, Maru, D., Manyam, G. C., Broom, B., Boige, V., Perez-Villamil, B., Laderas, T., Salazar, R., Gray, J. W., Hanahan, D., Tabernero, J., Bernards, R., Friend, S. H., Laurent-Puig, P., Medema, J. P., Sadanandam, A., Wessels, L., Delorenzi, M., Kopetz, S., Vermeulen, L. & Tejpar, S., Nov 1 2015, In : Nature medicine. 21, 11, p. 1350-1356 7 p.

Research output: Contribution to journalArticle

1287 Scopus citations

Transmission electron microscopy as an orthogonal method to characterize protein aggregates

Sung, J. J., Pardeshi, N. N., Mulder, A. M., Mulligan, S. K., Quispe, J., On, K., Carragher, B., Potter, C. S., Carpenter, J. F. & Schneemann, A., Feb 2015, In : Journal of Pharmaceutical Sciences. 104, 2, p. 750-759 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Upregulation of ER signaling as an adaptive mechanism of cell survival in HER2-positive breast tumors treated with Anti-HER2 therapy

Giuliano, M., Hu, H., Wang, Y. C., Fu, X., Nardone, A., Herrera, S., Mao, S., Contreras, A., Gutierrez, C., Wang, T., Hilsenbeck, S. G., Angelis, C. D., Wang, N. J., Heiser, L. M., Gray, J. W., Lopez-Tarruella, S., Pavlick, A. C., Trivedi, M. V., Chamness, G. C., Chang, J. C. & 3 others, Osborne, C. K., Rimawi, M. F. & Schiff, R., Sep 1 2015, In : Clinical Cancer Research. 21, 17, p. 3995-4003 9 p.

Research output: Contribution to journalArticle

42 Scopus citations
2014

A community computational challenge to predict the activity of pairs of compounds

Cellworks Group & NCI DREAM Community, Dec 1 2014, In : Nature biotechnology. 32, 12, p. 1213-1222 10 p.

Research output: Contribution to journalArticle

119 Scopus citations

A community effort to assess and improve drug sensitivity prediction algorithms

NCI DREAM Community, Dec 1 2014, In : Nature biotechnology. 32, 12, p. 1202-1212 11 p.

Research output: Contribution to journalArticle

283 Scopus citations

Copy Number Gain of hsa-miR-569 at 3q26.2 Leads to Loss of TP53INP1 and Aggressiveness of Epithelial Cancers

Chaluvally-Raghavan, P., Zhang, F., Pradeep, S., Hamilton, M. P., Zhao, X., Rupaimoole, R., Moss, T., Lu, Y., Yu, S., Pecot, C. V., Aure, M. R., Peuget, S., Rodriguez-Aguayo, C., Han, H. D., Zhang, D., Venkatanarayan, A., Krohn, M., Kristensen, V. N., Gagea, M., Ram, P. & 11 others, Liu, W., Lopez-Berestein, G., Lorenzi, P. L., Børresen-Dale, A. L., Chin, K., Gray, J., Dusetti, N. J., McGuire, S. E., Flores, E. R., Sood, A. K. & Mills, G. B., Dec 8 2014, In : Cancer Cell. 26, 6, p. 863-879 17 p.

Research output: Contribution to journalArticle

31 Scopus citations

Exact reconstruction of gene regulatory networks using compressive sensing

Chang, Y. H., Gray, J. W. & Tomlin, C. J., Dec 14 2014, In : BMC bioinformatics. 15, 1, 400.

Research output: Contribution to journalArticle

22 Scopus citations

Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase

Fu, X., Creighton, C. J., Biswal, N. C., Kumar, V., Shea, M., Herrera, S., Contreras, A., Gutierrez, C., Wang, T., Nanda, S., Giuliano, M., Morrison, G., Nardone, A., Karlin, K. L., Westbrook, T. F., Heiser, L. M., Anur, P., Spellman, P., Guichard, S. M., Smith, P. D. & 10 others, Davies, B. R., Klinowska, T., Lee, A. V., Mills, G. B., Rimawi, M. F., Hilsenbeck, S. G., Gray, J. W., Joshi, A., Osborne, C. K. & Schiff, R., Sep 11 2014, In : Breast Cancer Research. 16, 5, 430.

Research output: Contribution to journalArticle

45 Scopus citations

Photoactivated localization microscopy with Bimolecular Fluorescence Complementation (BiFC-PALM) for nanoscale imaging of protein-protein interactions in cells

Nickerson, A., Huang, T., Lin, L. J. & Nan, X., Jun 25 2014, In : PloS one. 9, 6, e100589.

Research output: Contribution to journalArticle

43 Scopus citations
2013

A robust prognostic signature for hormone-positive node-negative breast cancer

Griffith, O. L., Pepin, F., Enache, O. M., Heiser, L. M., Collisson, E. A., Spellman, P. T. & Gray, J. W., Oct 11 2013, In : Genome Medicine. 5, 10, 92.

Research output: Contribution to journalArticle

11 Scopus citations

Metrics other than potency reveal systematic variation in responses to cancer drugs

Fallahi-Sichani, M., Honarnejad, S., Heiser, L. M., Gray, J. W. & Sorger, P. K., Nov 1 2013, In : Nature Chemical Biology. 9, 11, p. 708-714 7 p.

Research output: Contribution to journalArticle

155 Scopus citations

Modeling precision treatment of breast cancer

Daemen, A., Griffith, O. L., Heiser, L. M., Wang, N. J., Enache, O. M., Sanborn, Z., Pepin, F., Durinck, S., Korkola, J. E., Griffith, M., Hur, J. S., Huh, N., Chung, J., Cope, L., Fackler, M. J., Umbricht, C., Sukumar, S., Seth, P., Sukhatme, V. P., Jakkula, L. R. & 7 others, Lu, Y., Mills, G. B., Cho, R. J., Collisson, E. A., van't Veer, L. J., Spellman, P. T. & Gray, J. W., Dec 10 2013, In : Genome biology. 14, 10, R110.

Research output: Contribution to journalArticle

Open Access
140 Scopus citations

p21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils

Itakura, A., Aslan, J. E., Kusanto, B. T., Phillips, K. G., Porter, J. E., Newton, P. K., Nan, X., Insall, R. H., Chernoff, J. & McCarty, O. J. T., Sep 3 2013, In : PloS one. 8, 9, e73063.

Research output: Contribution to journalArticle

25 Scopus citations

Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling

Nan, X., Collisson, E. A., Lewis, S., Huang, J., Tamgüney, T. M., Liphardt, J. T., McCormick, F., Gray, J. W. & Chu, S., Nov 12 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 46, p. 18519-18524 6 p.

Research output: Contribution to journalArticle

91 Scopus citations

Structure-Activity Relationship of Nerve-Highlighting Fluorophores

Gibbs, S. L., Xie, Y., Goodwill, H. L., Nasr, K. A., Ashitate, Y., Madigan, V. J., Siclovan, T. M., Zavodszky, M., Tan Hehir, C. A. & Frangioni, J. V., Sep 9 2013, In : PloS one. 8, 9, e73493.

Research output: Contribution to journalArticle

21 Scopus citations

Topical dual-stain difference imaging for rapid intra-operative tumor identification in fresh specimens

Davis, S. C., Gibbs, S. L., Gunn, J. R. & Pogue, B. W., Dec 1 2013, In : Optics Letters. 38, 23, p. 5184-5187 4 p.

Research output: Contribution to journalArticle

24 Scopus citations
2012

A Central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma

Collisson, E. A., Trejo, C. L., Silva, J. M., Gu, S., Korkola, J. E., Heiser, L. M., Charles, R. P., Rabinovich, B. A., Hann, B., Dankort, D., Spellman, P. T., Phillips, W. A., Gray, J. W. & McMahon, M., Aug 1 2012, In : Cancer discovery. 2, 8, p. 685-693 9 p.

Research output: Contribution to journalArticle

146 Scopus citations

ATM Suppresses SATB1-Induced Malignant Progression in Breast Epithelial Cells

Ordinario, E., Han, H. J., Furuta, S., Heiser, L. M., Jakkula, L. R., Rodier, F., Spellman, P. T., Campisi, J., Gray, J. W., Bissell, M. J., Kohwi, Y. & Kohwi-Shigematsu, T., Dec 10 2012, In : PloS one. 7, 12, e51786.

Research output: Contribution to journalArticle

17 Scopus citations

Bayesian Inference of Signaling Network Topology in a Cancer Cell Line

Hill, S. M., Lu, Y., Molina, J., Heiser, L. M., Spellman, P. T., Speed, T. P., Gray, J. W., Mills, G. B. & Mukherjee, S., Nov 1 2012, In : Bioinformatics. 28, 21, p. 2804-2810 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Subtype and pathway specific responses to anticancer compounds in breast cancer

Heiser, L. M., Sadanandam, A., Kuo, W. L., Benz, S. C., Goldstein, T. C., Ng, S., Gibb, W. J., Wang, N., Ziyad, S., Tong, F., Bayani, N., Hu, Z., Billig, J. I., Dueregger, A., Lewis, S., Jakkula, L., Korkola, J. E., Durinck, S., Pepin, F., Guan, Y. & 23 others, Purdom, E., Neuvial, P., Bengtsson, H., Wood, K. W., Smith, P. G., Vassilev, L. T., Hennessy, B. T., Greshock, J., Bachman, K. E., Hardwicke, M. A., Park, J. W., Marton, L. J., Wolf, D. M., Collisson, E. A., Neve, R. M., Mills, G. B., Speed, T. P., Feiler, H. S., Richard, F. W., Haussler, D., Stuart, J. M., Gray, J. W. & Spellman, P. T., Feb 21 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 8, p. 2724-2729 6 p.

Research output: Contribution to journalArticle

274 Scopus citations

Toolbox for non-intrusive structural and functional analysis of recombinant VLP based vaccines: A case study with hepatitis B vaccine

Mulder, A. M., Carragher, B., Towne, V., Meng, Y., Wang, Y., Dieter, L., Potter, C. S., Washabaugh, M. W., Sitrin, R. D. & Zhao, Q., Apr 6 2012, In : PloS one. 7, 4, e33235.

Research output: Contribution to journalArticle

37 Scopus citations
2011

Integrated genomic analyses of ovarian carcinoma

Bell, D., Berchuck, A., Birrer, M., Chien, J., Cramer, D. W., Dao, F., Dhir, R., Disaia, P., Gabra, H., Glenn, P., Godwin, A. K., Gross, J., Hartmann, L., Huang, M., Huntsman, D. G., Iacocca, M., Imielinski, M., Kalloger, S., Karlan, B. Y., Levine, D. A. & 240 others, Mills, G., Morrison, C., Mutch, D., Olvera, N., Orsulic, S., Park, K., Petrelli, N., Rabeno, B., Rader, J. S., Sikic, B. I., Smith-Mccune, K., Sood, A. K., Bowtell, D., Penny, R., Testa, J. R., Chang, K., Dinh, H. H., Drummond, J. A., Fowler, G., Gunaratne, P., Hawes, A. C., Kovar, C. L., Lewis, L. R., Morgan, M. B., Newsham, I. F., Santibanez, J., Reid, J. G., Trevino, L. R., Wu, Y. Q., Wang, M., Muzny, D. M., Wheeler, D. A., Gibbs, R. A., Getz, G., Lawrence, M. S., Cibulskis, K., Sivachenko, A. Y., Sougnez, C., Voet, D., Wilkinson, J., Bloom, T., Ardlie, K., Fennell, T., Baldwin, J., Gabriel, S., Lander, E. S., Ding, L., Fulton, R. S., Koboldt, D. C., McLellan, M. D., Wylie, T., Walker, J., O'Laughlin, M., Dooling, D. J., Fulton, L., Abbott, R., Dees, N. D., Zhang, Q., Kandoth, C., Wendl, M., Schierding, W., Shen, D., Harris, C. C., Schmidt, H., Kalicki, J., Delehaunty, K. D., Fronick, C. C., Demeter, R., Cook, L., Wallis, J. W., Lin, L., Magrini, V. J., Hodges, J. S., Eldred, J. M., Smith, S. M., Pohl, C. S., Vandin, F., Raphael, B. J., Weinstock, G. M., Mardis, E. R., Wilson, R. K., Meyerson, M., Winckler, W., Verhaak, R. G. W., Carter, S. L., Mermel, C. H., Saksena, G., Nguyen, H., Onofrio, R. C., Hubbard, D., Gupta, S., Crenshaw, A., Ramos, A. H., Chin, L., Protopopov, A., Zhang, J., Kim, T. M., Perna, I., Xiao, Y., Zhang, H., Ren, G., Sathiamoorthy, N., Park, R. W., Lee, E., Park, P. J., Kucherlapati, R., Absher, D. M., Waite, L., Sherlock, G., Brooks, J. D., Li, J. Z., Xu, J., Myers, R. M., Laird, P. W., Cope, L., Herman, J. G., Shen, H., Weisenberger, D. J., Noushmehr, H., Pan, F., Triche, T., Berman, B. P., Van Den Berg, D. J., Buckley, J., Baylin, S. B., Spellman, P. T., Purdom, E., Neuvial, P., Bengtsson, H., Jakkula, L. R., Durinck, S., Han, J., Dorton, S., Marr, H., Choi, Y. G., Wang, V., Wang, N. J., Ngai, J., Conboy, J. G., Parvin, B., Feiler, H. S., Speed, T. P., Gray, J. W., Socci, N. D., Liang, Y., Taylor, B. S., Schultz, N., Borsu, L., Lash, A. E., Brennan, C., Viale, A., Sander, C., Ladanyi, M., Hoadley, K. A., Meng, S., Du, Y., Shi, Y., Li, L., Turman, Y. J., Zang, D., Helms, E. B., Balu, S., Zhou, X., Wu, J., Topal, M. D., Hayes, D. N., Perou, C. M., Wu, C. J., Shukla, S., Sivachenko, A., Jing, R., Liu, Y., Noble, M., Carter, H., Kim, D., Karchin, R., Korkola, J. E., Heiser, L. M., Cho, R. J., Hu, Z., Cerami, E., Olshen, A., Reva, B., Antipin, Y., Shen, R., Mankoo, P., Sheridan, R., Ciriello, G., Chang, W. K., Bernanke, J. A., Haussler, D., Benz, C. C., Stuart, J. M., Benz, S. C., Sanborn, J. Z., Vaske, C. J., Zhu, J., Szeto, C., Scott, G. K., Yau, C., Wilkerson, M. D., Zhang, N., Akbani, R., Baggerly, K. A., Yung, W. K., Weinstein, J. N., Shelton, T., Grimm, D., Hatfield, M., Morris, S., Yena, P., Rhodes, P., Sherman, M., Paulauskis, J., Millis, S., Kahn, A., Greene, J. M., Sfeir, R., Jensen, M. A., Chen, J., Whitmore, J., Alonso, S., Jordan, J., Chu, A., Barker, A., Compton, C., Eley, G., Ferguson, M., Fielding, P., Gerhard, D. S., Myles, R., Schaefer, C., Mills Shaw, K. R., Vaught, J., Vockley, J. B., Good, P. J., Guyer, M. S., Ozenberger, B., Peterson, J. & Thomson, E., Jun 30 2011, In : Nature. 474, 7353, p. 609-615 7 p.

Research output: Contribution to journalArticle

3923 Scopus citations
2010

A Toolbox for ab initio 3-D reconstructions in single-particle electron microscopy

Voss, N. R., Lyumkis, D., Cheng, A., Lau, P. W., Mulder, A., Lander, G. C., Brignole, E. J., Fellmann, D., Irving, C., Jacovetty, E. L., Leung, A., Pulokas, J., Quispe, J. D., Winkler, H., Yoshioka, C., Carragher, B. & Potter, C. S., Mar 1 2010, In : Journal of Structural Biology. 169, 3, p. 389-398 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Visualizing ribosome biogenesis: Parallel assembly pathways for the 30S subunit

Mulder, A. M., Yoshioka, C., Beck, A. H., Bunner, A. E., Milligan, R. A., Potter, C. S., Carragher, B. & Williamson, J. R., Oct 29 2010, In : Science. 330, 6004, p. 673-677 5 p.

Research output: Contribution to journalArticle

122 Scopus citations
2009

A new model for binding of kinesin 13 to curved microtubule protofilaments

Mulder, A. M., Glavis-Bloom, A., Moores, C. A., Wagenbach, M., Carragher, B., Wordeman, L. & Milligan, R. A., Apr 6 2009, In : Journal of Cell Biology. 185, 1, p. 51-57 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Appion: An integrated, database-driven pipeline to facilitate EM image processing

Lander, G. C., Stagg, S. M., Voss, N. R., Cheng, A., Fellmann, D., Pulokas, J., Yoshioka, C., Irving, C., Mulder, A., Lau, P. W., Lyumkis, D., Potter, C. S. & Carragher, B., Apr 1 2009, In : Journal of Structural Biology. 166, 1, p. 95-102 8 p.

Research output: Contribution to journalArticle

438 Scopus citations

A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047

Kuo, W. L., Das, D., Ziyad, S., Bhattacharya, S., Gibb, W. J., Heiser, L. M., Sadanandam, A., Fontenay, G. V., Hu, Z., Wang, N., Bayani, N., Feiler, H. S., Neve, R. M., Wyrobek, A. J., Spellman, P. T., Marton, L. J. & Gray, J. W., Dec 14 2009, In : BMC Medicine. 7, 77.

Research output: Contribution to journalArticle

25 Scopus citations

Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition

Mirzoeva, O. K., Das, D., Heiser, L. M., Bhattacharya, S., Siwak, D., Gendelman, R., Bayani, N., Wang, N. J., Neve, R. M., Guan, Y., Hu, Z., Knight, Z., Feiler, H. S., Gascard, P., Parvin, B., Spellman, P. T., Shokat, K. M., Wyrobek, A. J., Bissell, M. J., McCormick, F. & 4 others, Kuo, W. L., Mills, G. B., Gray, J. W. & Korn, W. M., Jan 15 2009, In : Cancer Research. 69, 2, p. 565-572 8 p.

Research output: Contribution to journalArticle

274 Scopus citations

Integrated analysis of breast cancer cell lines reveals unique signaling pathways

Heiser, L. M., Wang, N. J., Talcott, C. L., Laderoute, K. R., Knapp, M., Guan, Y., Hu, Z., Ziyad, S., Weber, B. L., Laquerre, S., Jackson, J. R., Wooster, R. F., Kuo, W., Gray, J. W. & Spellman, P. T., Mar 25 2009, In : Genome biology. 10, 3, R31.

Research output: Contribution to journalArticle

51 Scopus citations
2008

Organelle tracking in a living cell with microsecond time resolution and nanometer spatial precision

Nan, X., Sims, P. A. & Xie, X. S., Apr 4 2008, In : ChemPhysChem. 9, 5, p. 707-712 6 p.

Research output: Contribution to journalArticle

121 Scopus citations
2007

Analysis of molecular inversion probe performance for allele copy number determination

Wang, Y., Moorhead, M., Karlin-Neumann, G., Wang, N. J., Ireland, J., Lin, S., Chen, C., Heiser, L. M., Chin, K., Esserman, L., Gray, J. W., Spellman, P. T. & Faham, M., Nov 20 2007, In : Genome biology. 8, 11, R246.

Research output: Contribution to journalArticle

50 Scopus citations

Dynamic circuitry for updating spatial representations. III. From neurons to behavior

Berman, R. A., Heiser, L. M., Dunn, C. A., Saunders, R. C. & Colby, C. L., Jul 1 2007, In : Journal of neurophysiology. 98, 1, p. 105-121 17 p.

Research output: Contribution to journalArticle

22 Scopus citations
2006

Endocannabinoid metabolism in the absence of fatty acid amide hydrolase (FAAH): Discovery of phosphorylcholine derivatives of N-acyl ethanolamines

Mulder, A. M. & Cravatt, B. F., Sep 26 2006, In : Biochemistry. 45, 38, p. 11267-11277 11 p.

Research output: Contribution to journalArticle

35 Scopus citations

Intracellular imaging of HCV RNA and cellular lipids by using simultaneous two-photon fluorescence and coherent anti-stokes Raman scattering microscopies

Nan, X., Tonary, A. M., Stolow, A., Xie, X. S. & Pezacki, J. P., Dec 1 2006, In : ChemBioChem. 7, 12, p. 1895-1897 3 p.

Research output: Contribution to journalArticle

59 Scopus citations

Nonperturbative chemical imaging of organelle transport in living cells with coherent anti-Stokes Raman scattering microscopy

Nan, X., Potma, E. O. & Xie, X. S., Jan 1 2006, In : Biophysical Journal. 91, 2, p. 728-735 8 p.

Research output: Contribution to journalArticle

178 Scopus citations

Peroxisome proliferator-activated receptor α antagonism inhibits hepatitis C virus replication

Rakic, B., Sagan, S. M., Noestheden, M., Bélanger, S., Nan, X., Evans, C. L., Xie, X. S. & Pezacki, J. P., Jan 1 2006, In : Chemistry and Biology. 13, 1, p. 23-30 8 p.

Research output: Contribution to journalArticle

68 Scopus citations

Spatial updating in area LIP is independent of saccade direction

Heiser, L. M. & Colby, C. L., May 1 2006, In : Journal of neurophysiology. 95, 5, p. 2751-2767 17 p.

Research output: Contribution to journalArticle

65 Scopus citations
2005

Corollary discharge and spatial updating: When the brain is split, is space still unified?

Colby, C. L., Berman, R. A., Heiser, L. M. & Saunders, R. C., Oct 24 2005, In : Progress in Brain Research. 149, p. 187-205 19 p.

Research output: Contribution to journalArticle

23 Scopus citations

Dynamic circuitry for updating spatial representations. I. Behavioral evidence for interhemispheric transfer in the split-brain macaque

Berman, R. A., Heiser, L. M., Saunders, R. C. & Colby, C. L., Nov 1 2005, In : Journal of neurophysiology. 94, 5, p. 3228-3248 21 p.

Research output: Contribution to journalArticle

24 Scopus citations