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2009
39 Scopus citations

Interaction of the Hereditary Hemochromatosis Protein HFE with Transferrin Receptor 2 Is Required for Transferrin-Induced Hepcidin Expression

Gao, J., Chen, J., Kramer, M., Tsukamoto, H., Zhang, A. S. & Enns, C. A., Mar 4 2009, In : Cell Metabolism. 9, 3, p. 217-227 11 p.

Research output: Contribution to journalArticle

208 Scopus citations

Lung tumor promotion by curcumin

Dance-Barnes, S. T., Kock, N. D., Moore, J. E., Lin, E. Y., Mosley, L. J., D'Agostino, R. B., Mccoy, T. P., Townsend, A. J. & Miller, M. S., Jun 15 2009, In : Carcinogenesis. 30, 6, p. 1016-1023 8 p.

Research output: Contribution to journalArticle

60 Scopus citations
50 Scopus citations

Mitogen-activated protein kinase-activated kinase RSK2 plays a role in innate immune responses to influenza virus infection

Kakugawa, S., Shimojima, M., Goto, H., Horimoto, T., Oshimori, N., Neumann, G., Yamamoto, T. & Kawaoka, Y., Mar 1 2009, In : Journal of virology. 83, 6, p. 2510-2517 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation

Stylli, S. S., Stacey, T. T. I., Verhagen, A. M., Xu, S. S., Pass, I., Courtneidge, S. A. & Lock, P., Aug 1 2009, In : Journal of Cell Science. 122, 15, p. 2727-2740 14 p.

Research output: Contribution to journalArticle

85 Scopus citations

Novel p47phox-related organizers regulate localized NADPH oxidase 1 (Nox1) activity

Gianni, D., Diaz, B., Taulet, N., Fowler, B., Courtneidge, S. A. & Bokoch, G. M., Sep 15 2009, In : Science signaling. 2, 88, p. ra54

Research output: Contribution to journalArticle

68 Scopus citations

Optical imaging of the peri-tumoral inflammatory response in breast cancer

Sista, A. K., Knebel, R. J., Tavri, S., Johansson, M., DeNardo, D. G., Boddington, S. E., Kishore, S. A., Ansari, C., Reinhart, V., Coakley, F. V., Coussens, L. M. & Daldrup-Link, H. E., Nov 11 2009, In : Journal of translational medicine. 7, 94.

Research output: Contribution to journalArticle

6 Scopus citations

Pregnancy and breast cancer: When they collide

Lyons, T. R., Schedin, P. J. & Borges, V. F., Apr 21 2009, In : Journal of Mammary Gland Biology and Neoplasia. 14, 2, p. 87-98 12 p.

Research output: Contribution to journalArticle

117 Scopus citations

Processing of hemojuvelin requires retrograde trafficking to the Golgi in HepG2 cells

Maxson, J. E., Enns, C. A. & Zhang, A. S., Feb 19 2009, In : Blood. 113, 8, p. 1786-1793 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Pulmonary inflammation triggered by ricin toxin requires macrophages and IL-1 signaling

Lindauer, M. L., Wong, J., Iwakura, Y. & Magun, B. E., Jul 15 2009, In : Journal of Immunology. 183, 2, p. 1419-1426 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Quantification of spatial parameters in 3D cellular constructs using graph theory

Lund, A. W., Bilgin, C. C., Hasan, M. A., McKeen, L. M., Stegemann, J. P., Yener, B., Zaki, M. J. & Plopper, G. E., Dec 9 2009, In : Journal of Biomedicine and Biotechnology. 2009, 928286.

Research output: Contribution to journalArticle

8 Scopus citations

Reverse signaling by glycosylphosphatidylinositol-linked manduca ephrin requires a src family kinase to restrict neuronal migration in vivo

Coate, T. M., Swanson, T. L. & Copenhaver, P. F., Mar 18 2009, In : Journal of Neuroscience. 29, 11, p. 3404-3418 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

Site-specific cleavage of BMP4 by furin, PC6, and PC7

Nelsen, S. M. & Christian, J. L., Oct 2 2009, In : Journal of Biological Chemistry. 284, 40, p. 27157-27166 10 p.

Research output: Contribution to journalArticle

46 Scopus citations

Tamoxifen induces pleiotrophic changes in mammary stroma resulting in extracellular matrix that suppresses transformed phenotypes

Hattar, R., Maller, O., McDaniel, S., Hansen, K. C., Hedman, K. J., Lyons, T. R., Lucia, S., Wilson, R. S. & Schedin, P., Jan 27 2009, In : Breast Cancer Research. 11, 1, R5.

Research output: Contribution to journalArticle

45 Scopus citations

Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: Implications for psoriasis pathogenesis

Harper, E. G., Guo, C., Rizzo, H., Lillis, J. V., Kurtz, S. E., Skorcheva, I., Purdy, D., Fitch, E., Iordanov, M. & Blauvelt, A., Sep 1 2009, In : Journal of Investigative Dermatology. 129, 9, p. 2175-2183 9 p.

Research output: Contribution to journalArticle

270 Scopus citations

The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: Correlates with human disease

Elia, L., Quintavalle, M., Zhang, J., Contu, R., Cossu, L., Latronico, M. V. G., Peterson, K. L., Indolfi, C., Catalucci, D., Chen, J., Courtneidge, S. A. & Condorelli, G., Oct 15 2009, In : Cell Death and Differentiation. 16, 12, p. 1590-1598 9 p.

Research output: Contribution to journalArticle

392 Scopus citations

The novel adaptor protein tks4 (SH3PXD2B) is required for functional podosome formation

Buschman, M. D., Bromann, P. A., Cejudo-Martin, P., Wen, F., Pass, I. & Courtneidge, S. A., Mar 1 2009, In : Molecular biology of the cell. 20, 5, p. 1302-1311 10 p.

Research output: Contribution to journalArticle

104 Scopus citations

Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation

Diaz, B., Shani, G., Pass, I., Anderson, D., Quintavalle, M. & Courtneidge, S. A., Sep 15 2009, In : Science signaling. 2, 88, p. ra53

Research output: Contribution to journalArticle

153 Scopus citations

Tks5 recruits AFAP-110, p190RhoGAP, and cortactin for podosome formation

Crimaldi, L., Courtneidge, S. A. & Gimona, M., Sep 10 2009, In : Experimental Cell Research. 315, 15, p. 2581-2592 12 p.

Research output: Contribution to journalArticle

40 Scopus citations

Transferrin-directed internalization and cycling of transferrin receptor 2

Chen, J., Wang, J., Meyers, K. R. & Enns, C. A., Oct 1 2009, In : Traffic. 10, 10, p. 1488-1501 14 p.

Research output: Contribution to journalArticle

38 Scopus citations

Treg cells meet their limit

Hogquist, K. A. & Moran, A. E., May 28 2009, In : Nature Immunology. 10, 6, p. 565-566 2 p.

Research output: Contribution to journalArticle

4 Scopus citations

Western-style diets induce oxidative stress and dysregulate immune responses in the colon in a mouse model of sporadic colon cancer

Erdelyi, I., Levenkova, N., Lin, E. Y., Pinto, J. T., Lipkin, M., Quimby, F. W. & Holt, P. R., Nov 1 2009, In : Journal of Nutrition. 139, 11, p. 2072-2078 7 p.

Research output: Contribution to journalArticle

57 Scopus citations
2008

A pilot surrogate endpoint biomarker study of celecoxib in oral premalignant lesions

Wirth, L. J., Krane, J. F., Li, Y., Othus, M., Moran, A. E., Dorfman, D. M., Norris, C. M., Goguen, L., Posner, M. R., Haddad, R. I. & Bertagnolli, M. M., Oct 1 2008, In : Cancer Prevention Research. 1, 5, p. 339-348 10 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

A role for the podosome/invadopodia scaffold protein Tks5 in tumor growth in vivo

Blouw, B., Seals, D. F., Pass, I., Diaz, B. & Courtneidge, S. A., Sep 4 2008, In : European Journal of Cell Biology. 87, 8-9, p. 555-567 13 p.

Research output: Contribution to journalArticle

77 Scopus citations

Fas ligand-induced proinflammatory transcriptional responses in reconstructed human epidermis: Recruitment of the epidermal growth factor receptor and activation of MAP kinases

Farley, S. M., Purdy, D. E., Ryabinina, O. P., Schneider, P., Magun, B. E. & Iordanov, M. S., Jan 11 2008, In : Journal of Biological Chemistry. 283, 2, p. 919-928 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

FGF-dependent mechanosensory organ patterning in zebrafish

Nechiporuk, A. & Raible, D. W., Jun 27 2008, In : Science. 320, 5884, p. 1774-1777 4 p.

Research output: Contribution to journalArticle

129 Scopus citations

Hepatic macrophage iron aggravates experimental alcoholic steatohepatitis

Xiong, S., She, H., Zhang, A. S., Wang, J., Mkrtchyan, H., Dynnyk, A., Gordeuk, V. R., French, S. W., Enns, C. A. & Tsukamoto, H., Sep 1 2008, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 295, 3, p. G512-G521

Research output: Contribution to journalArticle

32 Scopus citations

Loss of singleminded-2s in the mouse mammary gland induces an epithelial-mesenchymal transition associated with up-regulation of slug and matrix metalloprotease 2

Laffin, B., Wellberg, E., Kwak, H. I., Burghardt, R. C., Metz, R. P., Gustafson, T., Schedin, P. & Porter, W. W., Mar 1 2008, In : Molecular and cellular biology. 28, 6, p. 1936-1946 11 p.

Research output: Contribution to journalArticle

67 Scopus citations

Mouse model of hemolytic-uremic syndrome caused by endotoxin-free Shiga toxin 2 (Stx2) and protection from lethal outcome by anti-Stx2 antibody

Sauter, K. A. D., Melton-Celsa, A. R., Larkin, K., Troxell, M. L., O'Brien, A. D. & Magun, B. E., Oct 1 2008, In : Infection and Immunity. 76, 10, p. 4469-4478 10 p.

Research output: Contribution to journalArticle

61 Scopus citations

Neogenin-mediated hemojuvelin shedding occurs after hemojuvelin traffics to the plasma membrane

Zhang, A. S., Yang, F., Meyer, K., Hernandez, C., Chapman-Arvedson, T., Bjorkman, P. J. & Enns, C. A., Jun 20 2008, In : Journal of Biological Chemistry. 283, 25, p. 17494-17502 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Osteogenic differentiation of mesenchymal stem cells in defined protein beads

Lund, A. W., Bush, J. A., Plopper, G. E. & Stegemann, J. P., Oct 1 2008, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 87, 1, p. 213-221 9 p.

Research output: Contribution to journalArticle

38 Scopus citations
10 Scopus citations

The hereditary hemochromatosis protein, HFE, inhibits iron uptake via down-regulation of Zip14 in HepG2 Cells

Gao, J., Zhao, N., Knutson, M. D. & Enns, C. A., Aug 1 2008, In : Journal of Biological Chemistry. 283, 31, p. 21462-21468 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin

Kenny, H. A., Kaur, S., Coussens, L. M. & Lengyel, E., Apr 1 2008, In : Journal of Clinical Investigation. 118, 4, p. 1367-1379 13 p.

Research output: Contribution to journalArticle

228 Scopus citations

The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1

Gianni, D., Bohl, B., Courtneidge, S. A. & Bokoch, G. M., Jul 1 2008, In : Molecular biology of the cell. 19, 7, p. 2984-2994 11 p.

Research output: Contribution to journalArticle

97 Scopus citations

The mechanisms of spindle pole formation for the proper chromosome segregation

Ohsugi, M. & Oshimori, N., Dec 1 2008, In : Seikagaku. 80, 3, p. 210-214 5 p.

Research output: Contribution to journalArticle

Use of Nramp2-transfected Chinese hamster ovary cells and reticulocytes from mk/mk mice to study iron transport mechanisms

Zhang, A. S., Canonne-Hergaux, F., Gruenheid, S., Gros, P. & Ponka, P., Oct 1 2008, In : Experimental hematology. 36, 10, p. 1227-1235 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Vesicular glutamate transporter 3 is required for synaptic transmission in zebrafish hair cells

Obholzer, N., Wolfson, S., Trapani, J. G., Mo, W., Nechiporuk, A., Busch-Nentwich, E., Seiler, C., Sidi, S., Söllner, C., Duncan, R. N., Boehland, A. & Nicolson, T., Feb 27 2008, In : Journal of Neuroscience. 28, 9, p. 2110-2118 9 p.

Research output: Contribution to journalArticle

178 Scopus citations

Zebrafish dorsal root ganglia neural precursor cells adopt a glial fate in the absence of neurogenin1

McGraw, H. F., Nechiporuk, A. & Raible, D. W., Nov 19 2008, In : Journal of Neuroscience. 28, 47, p. 12558-12569 12 p.

Research output: Contribution to journalArticle

48 Scopus citations
2007

An inducible system for expression and validation of the specificity of short hairpin RNA in mammalian cells

Ma, H. T., On, K. F., Tsang, Y. H. & Poon, R. Y. C., Feb 1 2007, In : Nucleic acids research. 35, 4, e22.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Direct interorganellar transfer of iron from endosome to mitochondrion

Sheftel, A. D., Zhang, A. S., Brown, C., Shirihai, O. S. & Ponka, P., Jul 1 2007, In : Blood. 110, 1, p. 125-132 8 p.

Research output: Contribution to journalArticle

171 Scopus citations

Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors

Wyckoff, J. B., Wang, Y., Lin, E. Y., Li, J. F., Goswami, S., Stanley, E. R., Segall, J. E., Pollard, J. W. & Condeelis, J., Mar 15 2007, In : Cancer Research. 67, 6, p. 2649-2656 8 p.

Research output: Contribution to journalArticle

640 Scopus citations

Distinctive features of angiogenesis and lymphangiogenesis determine their functionality during de novo tumor development

Eichten, A., Hyun, W. C. & Coussens, L. M., Jun 1 2007, In : Cancer Research. 67, 11, p. 5211-5220 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Eph receptor expression defines midline boundaries for ephrin-positive migratory neurons in the enteric nervous system of Manduca sexta

Coate, T. M., Swanson, T. L., Proctor, T. M., Nighorn, A. J. & Copenhaver, P. F., May 10 2007, In : Journal of Comparative Neurology. 502, 2, p. 175-191 17 p.

Research output: Contribution to journalArticle

8 Scopus citations

Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin

Zhang, A. S., Anderson, S. A., Meyers, K. R., Hernandez, C., Eisenstein, R. S. & Enns, C. A., Apr 27 2007, In : Journal of Biological Chemistry. 282, 17, p. 12547-12556 10 p.

Research output: Contribution to journalArticle

91 Scopus citations

HFE modulates transferrin receptor 2 levels in hepatoma cells via interactions that differ from transferrin receptor 1-HFE interactions

Chen, J., Chloupková, M., Gao, J., Chapman-Arvedson, T. L. & Enns, C. A., Dec 21 2007, In : Journal of Biological Chemistry. 282, 51, p. 36862-36870 9 p.

Research output: Contribution to journalArticle

69 Scopus citations

Hu/Mu protin oligonucleotide microarray: Dual-species array for profiling protease and protease inhibitor gene expression in tumors and their microenvironment

Schwartz, D. R., Moin, K., Yao, B., Matrisian, L. M., Coussens, L. M., Bugge, T. H., Fingleton, B., Acuff, H. B., Sinnamon, M., Nassar, H., Platts, A. E., Krawetz, S. A., Linebaugh, B. E. & Sloane, B. F., May 1 2007, In : Molecular Cancer Research. 5, 5, p. 443-454 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Inhibition of breast cancer growth and invasion by single-minded 2s

Kwak, H. I., Gustafson, T., Metz, R. P., Laffin, B., Schedin, P. & Porter, W. W., Feb 1 2007, In : Carcinogenesis. 28, 2, p. 259-266 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

Intrapulmonary delivery of ricin at high dosage triggers a systemic inflammatory response and glomerular damage

Wong, J., Korcheva, V., Jacoby, D. B. & Magun, B., May 2007, In : American Journal of Pathology. 170, 5, p. 1497-1510 14 p.

Research output: Contribution to journalArticle

41 Scopus citations