Research Output

Filter
Article
2016

Kif1B interacts with KBP to promote axon elongation by localizing a microtubule regulator to growth cones

Drerup, C. M., Lusk, S. & Nechiporuk, A., Jun 29 2016, In : Journal of Neuroscience. 36, 26, p. 7014-7026 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Lymphatic vessels regulate immune microenvironments in human and murine melanoma

Lund, A. W., Wagner, M., Fankhauser, M., Steinskog, E. S., Broggi, M. A., Spranger, S., Gajewski, T. F., Alitalo, K., Eikesdal, H. P., Wiig, H. & Swartz, M. A., Sep 1 2016, In : Journal of Clinical Investigation. 126, 9, p. 3389-3402 14 p.

Research output: Contribution to journalArticle

58 Scopus citations

Mammary epithelial cell phagocytosis downstream of TGF-β3 is characterized by adherens junction reorganization

Fornetti, J., Flanders, K. C., Henson, P. M., Tan, A. C., Borges, V. F. & Schedin, P., Feb 1 2016, In : Cell Death and Differentiation. 23, 2, p. 185-196 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

Manduca contactin regulates amyloid precursor protein-dependent neuronal migration

Ramaker, J. M., Swanson, T. L. & Copenhaver, P., Aug 17 2016, In : Journal of Neuroscience. 36, 33, p. 8757-8775 19 p.

Research output: Contribution to journalArticle

7 Scopus citations

MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment

Wilson, R. A., Espinosa-Diez, C., Kanner, N., Chatterjee, N., Ruhl, R., Hipfinger, C., Advani, S. J., Li, J., Khan, O. F., Franovic, A., Weis, S. M., Kumar, S., Coussens, L. M., Anderson, D. G., Chen, C. C., Cheresh, D. A. & Anand, S., Nov 25 2016, In : Nature communications. 7, 13597.

Research output: Contribution to journalArticle

22 Scopus citations

Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism-dystonia

Tuschl, K., Meyer, E., Valdivia, L. E., Zhao, N., Dadswell, C., Abdul-Sada, A., Hung, C. Y., Simpson, M. A., Chong, W. K., Jacques, T. S., Woltjer, R. L., Eaton, S., Gregory, A., Sanford, L., Kara, E., Houlden, H., Cuno, S. M., Prokisch, H., Valletta, L., Tiranti, V. & 20 others, Younis, R., Maher, E. R., Spencer, J., Straatman-Iwanowska, A., Gissen, P., Selim, L. A. M., Pintos-Morell, G., Coroleu-Lletget, W., Mohammad, S. S., Yoganathan, S., Dale, R. C., Thomas, M., Rihel, J., Bodamer, O. A., Enns, C. A., Hayflick, S. J., Clayton, P. T., Mills, P. B., Kurian, M. A. & Wilson, S. W., May 27 2016, In : Nature communications. 7, 11601.

Research output: Contribution to journalArticle

95 Scopus citations

Myoepithelial cells in lobular carcinoma in situ: Distribution and immunophenotype

Wang, Y., Jindal, S., Martel, M., Wu, Y., Schedin, P. & Troxell, M., Sep 1 2016, In : Human Pathology. 55, p. 126-134 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Neogenin facilitates the induction of hepcidin expression by hemojuvelin in the liver

Zhao, N., Maxson, J., Zhang, R. H., Wahedi, M., Enns, C. & Zhang, A-S., Jun 3 2016, In : Journal of Biological Chemistry. 291, 23, p. 12322-12335 14 p.

Research output: Contribution to journalArticle

21 Scopus citations

Non-invasive single-cell biomechanical analysis using live-imaging datasets

Pearson, Y. E., Lund, A. W., Lin, A. W. H., Ng, C. P., Alsuwaidi, A., Azzeh, S., Gater, D. L. & Teo, J. C. M., 2016, In : Journal of Cell Science. 129, 17, p. 3351-3364 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

PKCiota promotes ovarian tumor progression through deregulation of cyclin e

Nanos-Webb, A., Bui, T., Karakas, C., Zhang, D., Carey, J. P. W., Mills, G. B., Hunt, K. K. & Keyomarsi, K., May 12 2016, In : Oncogene. 35, 19, p. 2428-2440 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Quantitative extracellular matrix proteomics to study mammary and liver tissue microenvironments

Goddard, E. T., Hill, R. C., Barrett, A., Betts, C., Guo, Q., Maller, O., Borges, V. F., Hansen, K. C. & Schedin, P., Dec 1 2016, In : International Journal of Biochemistry and Cell Biology. 81, p. 223-232 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Senescence and cancer: An evolving inflammatory paradox

Ruhland, M. K., Coussens, L. & Stewart, S. A., Jan 1 2016, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1865, 1, p. 14-22 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

STX, a novel membrane estrogen receptor ligand, protects against amyloid-β toxicity

Gray, N. E., Zweig, J. A., Kawamoto, C., Quinn, J. & Copenhaver, P., Mar 15 2016, In : Journal of Alzheimer's Disease. 51, 2, p. 391-403 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

The Basis of Oncoimmunology

Palucka, A. K. & Coussens, L., Mar 10 2016, In : Cell. 164, 6, p. 1233-1247 15 p.

Research output: Contribution to journalArticle

290 Scopus citations

The Importance of the Saphenous Nerve in Ankle Surgery

Eglitis, N., Horn, J. L., Benninger, B. & Nelsen, S., May 1 2016, In : Anesthesia and Analgesia. 122, 5, p. 1704-1706 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

The role of Tks adaptor proteins in invadopodia formation, growth and metastasis of melanoma

Iizuka, S., Abdullah, C., Buschman, M. D., Diaz, B. & Courtneidge, S. A., 2016, In : Oncotarget. 7, 48, p. 78473-78486 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Tril targets Smad7 for degradation to allow hematopoietic specification in Xenopus embryos

Green, Y. S., Kwon, S., Mimoto, M. S., Xie, Y. & Christian, J. L., Nov 1 2016, In : Development (Cambridge). 143, 21, p. 4016-4026 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2015

A case-control analysis of oral contraceptive use and breast cancer subtypes in the African American Breast Cancer Epidemiology and Risk Consortium

Bethea, T. N., Rosenberg, L., Hong, C. C., Troester, M. A., Lunetta, K. L., Bandera, E. V., Schedin, P., Kolonel, L. N., Olshan, A. F., Ambrosone, C. B. & Palmer, J. R., Dec 14 2015, In : Breast Cancer Research. 17, 1, 22.

Research output: Contribution to journalArticle

23 Scopus citations

BRD4 is a novel therapeutic target for liver fibrosis

Ding, N., Hah, N., Yu, R. T., Sherman, M. H., Benner, C., Leblanc, M., He, M., Liddle, C., Downes, M. & Evans, R. M., Dec 22 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 51, p. 15713-15718 6 p.

Research output: Contribution to journalArticle

78 Scopus citations

Calcipotriol targets LRP6 to inhibit wnt signaling in pancreatic cancer

Arensman, M. D., Nguyen, P., Kershaw, K. M., Lay, A. R., Ostertag-Hill, C. A., Sherman, M. H., Downes, M., Liddle, C., Evans, R. M. & Dawson, D. W., Nov 2015, In : Molecular Cancer Research. 13, 11, p. 1509-1519 11 p.

Research output: Contribution to journalArticle

20 Scopus citations
11 Scopus citations

Expression of α-subunit of α-glucosidase II in adult mouse brain regions and selected organs

Anji, A., Miller, H., Raman, C., Phillips, M., Ciment, G. & Kumari, M., Jan 1 2015, In : Journal of Neuroscience Research. 93, 1, p. 82-93 12 p.

Research output: Contribution to journalArticle

Human mutant huntingtin disrupts vocal learning in transgenic songbirds

Liu, W. C., Kohn, J., Szwed, S. K., Pariser, E., Sepe, S., Haripal, B., Oshimori, N., Marsala, M., Miyanohara, A. & Lee, R., Nov 1 2015, In : Nature Neuroscience. 18, 11, p. 1617-1622 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Identification of variant-specific functions of PIK3CA by rapid phenotyping of rare mutations

Dogruluk, T., Tsang, Y. H., Espitia, M., Chen, F., Chen, T., Chong, Z., Appadurai, V., Dogruluk, A., Eterovic, A. K., Bonnen, P. E., Creighton, C. J., Chen, K., Mills, G. B. & Scott, K. L., Dec 15 2015, In : Cancer Research. 75, 24, p. 5341-5354 14 p.

Research output: Contribution to journalArticle

53 Scopus citations

Immune Response to Cancer Therapy: Mounting an Effective Antitumor Response and Mechanisms of Resistance

Medler, T. R., Cotechini, T. & Coussens, L., Sep 1 2015, In : Trends in Cancer. 1, 1, p. 66-75 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

Important Role of Menarche in Development of Estrogen Receptor-Negative Breast Cancer in African American Women

Ambrosone, C. B., Zirpoli, G., Hong, C. C., Yao, S., Troester, M. A., Bandera, E. V., Schedin, P., Bethea, T. N., Borges, V., Park, S. Y., Chandra, D., Rosenberg, L., Kolonel, L. N., Olshan, A. F. & Palmer, J. R., Sep 1 2015, In : Journal of the National Cancer Institute. 107, 9, djv172.

Research output: Contribution to journalArticle

27 Scopus citations

Kinase-independent role for CRAF-driving tumour radioresistance via CHK2

Advani, S. J., Camargo, M. F., Seguin, L., Mielgo, A., Anand, S., Hicks, A. M., Aguilera, J., Franovic, A., Weis, S. M. & Cheresh, D. A., Sep 3 2015, In : Nature communications. 6, 8154.

Research output: Contribution to journalArticle

17 Scopus citations

Low intracellular iron increases the stability of Matriptase-2

Zhao, N., Nizzi, C. P., Anderson, S. A., Wang, J., Ueno, A., Tsukamoto, H., Eisenstein, R. S., Enns, C. A. & Zhang, A. S., Feb 13 2015, In : Journal of Biological Chemistry. 290, 7, p. 4432-4446 15 p.

Research output: Contribution to journalArticle

30 Scopus citations

Molecular phenotype of breast cancer according to time since last pregnancy in a large cohort of young women

Collins, L. C., Gelber, S., Marotti, J. D., White, S., Ruddy, K., Brachtel, E. F., Schapira, L., Come, S. E., Borges, V. F., Schedin, P., Warner, E., Wensley, T., Tamimi, R. M., Winer, E. P. & Partridge, A. H., May 29 2015, In : Oncologist. 20, 7, p. 713-718 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Myoepithelial cell differentiation markers in ductal carcinoma in situ progression

Russell, T. D., Jindal, S., Agunbiade, S., Gao, D., Troxell, M., Borges, V. F. & Schedin, P., Nov 2015, In : American Journal of Pathology. 185, 11, p. 3076-3089 14 p.

Research output: Contribution to journalArticle

23 Scopus citations

Sustained endothelial expression of HoxA5 in vivo impairs pathological angiogenesis and tumor progression

Cuevas, I., Layman, H., Coussens, L. & Boudreau, N., Mar 30 2015, In : PloS one. 10, 3, e0121720.

Research output: Contribution to journalArticle

9 Scopus citations

TGF-β Promotes Heterogeneity and Drug Resistance in Squamous Cell Carcinoma

Oshimori, N., Oristian, D. & Fuchs, E., Feb 26 2015, In : Cell. 160, 5, p. 963-976 14 p.

Research output: Contribution to journalArticle

194 Scopus citations

TH2-polarized CD4+ T Cells and macrophages limit efficacy of radiotherapy

Shiao, S. L., Ruffell, B., De Nardo, D. G., Faddegon, B. A., Park, C. C. & Coussens, L., May 1 2015, In : Cancer immunology research. 3, 5, p. 518-525 8 p.

Research output: Contribution to journalArticle

101 Scopus citations

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers

Han, L., Diao, L., Yu, S., Xu, X., Li, J., Zhang, R., Yang, Y., Werner, H. M. J., Eterovic, A. K., Yuan, Y., Li, J., Nair, N., Minelli, R., Tsang, Y. H., Cheung, L. W. T., Jeong, K. J., Roszik, J., Ju, Z., Woodman, S. E., Lu, Y. & 4 others, Scott, K. L., Li, J. B., Mills, G. B. & Liang, H., Oct 12 2015, In : Cancer Cell. 28, 4, p. 515-528 14 p., 2143.

Research output: Contribution to journalArticle

177 Scopus citations

The invadopodia scaffold protein Tks5 is required for the growth of human breast cancer cells in vitro and in vivo

Blouw, B., Patel, M., Iizuka, S., Abdullah, C., You, W. K., Huang, X., Li, J. L., Diaz, B., Stallcup, W. B. & Courtneidge, S. A., Mar 31 2015, In : PloS one. 10, 3, e0121003.

Research output: Contribution to journalArticle

28 Scopus citations

The prodomain of BMP4 is necessary and sufficient to generate stable BMP4/7 heterodimers with enhanced bioactivity in vivo

Neugebauer, J. M., Kwon, S., Kim, H. S., Donley, N., Tilak, A., Sopory, S. & Christian, J. L., May 5 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 18, p. E2307-E2316

Research output: Contribution to journalArticle

16 Scopus citations

Wound healing-like immune program facilitates postpartum mammary gland involution and tumor progression

Martinson, H. A., Jindal, S., Durand-Rougely, C., Borges, V. F. & Schedin, P., Apr 15 2015, In : International Journal of Cancer. 136, 8, p. 1803-1813 11 p.

Research output: Contribution to journalArticle

37 Scopus citations
2014

A listeria vaccine and depletion of t-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice

Keenan, B. P., Saenger, Y., Kafrouni, M. I., Leubner, A., Lauer, P., Maitra, A., Rucki, A. A., Gunderson, A. J., Coussens, L. M., Brockstedt, D. G., Dubensky, T. W., Hassan, R., Armstrong, T. D. & Jaffee, E. M., Jun 2014, In : Gastroenterology. 146, 7, p. 1784-1794.e6

Research output: Contribution to journalArticle

66 Scopus citations

An integrin β 3-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition

Seguin, L., Kato, S., Franovic, A., Camargo, M. F., Lesperance, J., Elliott, K. C., Yebra, M., Mielgo, A., Lowy, A. M., Husain, H., Cascone, T., Diao, L., Wang, J., Wistuba, I. I., Heymach, J. V., Lippman, S. M., Desgrosellier, J. S., Anand, S., Weis, S. M. & Cheresh, D. A., Jan 1 2014, In : Nature Cell Biology. 16, 5, p. 457-468 12 p.

Research output: Contribution to journalArticle

189 Scopus citations
31 Scopus citations

Antiphospholipid antibodies promote tissue factor-dependent angiogenic switch and tumor progression

Wu, Y. Y., Nguyen, A. V., Wu, X. X., Loh, M., Vu, M., Zou, Y., Liu, Q., Guo, P., Wang, Y., Montgomery, L. L., Orlofsky, A., Rand, J. H. & Lin, E. Y., Dec 1 2014, In : American Journal of Pathology. 184, 12, p. 3359-3375 17 p.

Research output: Contribution to journalArticle

7 Scopus citations

B cells regulate macrophage phenotype and response to chemotherapy in squamous carcinomas

Affara, N. I., Ruffell, B., Medler, T. R., Gunderson, A. J., Johansson, M., Bornstein, S., Bergsland, E., Steinhoff, M., Li, Y., Gong, Q., Ma, Y., Wiesen, J. F., Wong, M. H., Kulesz-Martin, M., Irving, B. & Coussens, L. M., Jun 16 2014, In : Cancer Cell. 25, 6, p. 809-821 13 p.

Research output: Contribution to journalArticle

135 Scopus citations

Cellular origin of bladder neoplasia and tissue dynamics of its progression to invasive carcinoma

Shin, K., Lim, A., Odegaard, J. I., Honeycutt, J. D., Kawano, S., Hsieh, M. H. & Beachy, P. A., Jan 1 2014, In : Nature Cell Biology. 16, 5, p. 469-478 10 p.

Research output: Contribution to journalArticle

108 Scopus citations

Classification of current anticancer immunotherapies

Galluzzi, L., Vacchelli, E., Bravo-San Pedro, J. M., Buqué, A., Senovilla, L., Baracco, E. E., Bloy, N., Castoldi, F., Abastado, J. P., Agostinis, P., Apte, R. N., Aranda, F., Ayyoub, M., Beckhove, P., Blay, J. Y., Bracci, L., Caignard, A., Castelli, C., Cavallo, F., Celis, E. & 68 others, Cerundolo, V., Clayton, A., Colombo, M. P., Coussens, L., Dhodapkar, M. V., Eggermont, A. M., Fearon, D. T., Fridman, W. H., Fucíková, J., Gabrilovich, D. I., Galon, J., Garg, A., Ghiringhelli, F., Giaccone, G., Gilboa, E., Gnjatic, S., Hoos, A., Hosmalin, A., Jäger, D., Kalinski, P., Kärre, K., Kepp, O., Kiessling, R., Kirkwood, J. M., Klein, E., Knuth, A., Lewis, C. E., Liblau, R., Lotze, M. T., Lugli, E., Mach, J. P., Mattei, F., Mavilio, D., Melero, I., Melief, C. J., Mittendorf, E. A., Moretta, L., Odunsi, A., Okada, H., Palucka, A. K., Peter, M. E., Pienta, K. J., Porgador, A., Prendergast, G. C., Rabinovich, G. A., Restifo, N. P., Rizvi, N., Sautès-Fridman, C., Schreiber, H., Seliger, B., Shiku, H., Silva-Santos, B., Smyth, M. J., Speiser, D. E., Spisek, R., Srivastava, P. K., Talmadge, J. E., Tartour, E., Van Der Burg, S. H., Van Den Eynde, B. J., Vile, R., Wagner, H., Weber, J. S., Whiteside, T. L., Wolchok, J. D., Zitvogel, L., Zou, W. & Kroemer, G., 2014, In : Oncotarget. 5, 24, p. 12472-12508 37 p.

Research output: Contribution to journalArticle

Open Access
224 Scopus citations

Copy Number Gain of hsa-miR-569 at 3q26.2 Leads to Loss of TP53INP1 and Aggressiveness of Epithelial Cancers

Chaluvally-Raghavan, P., Zhang, F., Pradeep, S., Hamilton, M. P., Zhao, X., Rupaimoole, R., Moss, T., Lu, Y., Yu, S., Pecot, C. V., Aure, M. R., Peuget, S., Rodriguez-Aguayo, C., Han, H. D., Zhang, D., Venkatanarayan, A., Krohn, M., Kristensen, V. N., Gagea, M., Ram, P. & 11 others, Liu, W., Lopez-Berestein, G., Lorenzi, P. L., Børresen-Dale, A. L., Chin, K., Gray, J., Dusetti, N. J., McGuire, S. E., Flores, E. R., Sood, A. K. & Mills, G. B., Dec 8 2014, In : Cancer Cell. 26, 6, p. 863-879 17 p.

Research output: Contribution to journalArticle

31 Scopus citations

Cyclooxygenase-2-dependent lymphangiogenesis promotes nodal metastasis of postpartum breast cancer

Lyons, T. R., Borges, V. F., Betts, C. B., Guo, Q., Kapoor, P., Martinson, H. A., Jindal, S. & Schedin, P., Sep 2 2014, In : Journal of Clinical Investigation. 124, 9, p. 3901-3912 12 p.

Research output: Contribution to journalArticle

50 Scopus citations

Duality of the immune response in cancer: lessons learned from skin

Medler, T. R. & Coussens, L. M., Jan 1 2014, In : The Journal of investigative dermatology. 134, e1, p. E23-E28

Research output: Contribution to journalArticle

14 Scopus citations

Genetic disruption of the Sh3pxd2a gene reveals an essential role in mouse development and the existence of a novel isoform of Tks5

Cejudo-Martin, P., Yuen, A., Vlahovich, N., Lock, P., Courtneidge, S. A. & Díaz, B., Sep 26 2014, In : PloS one. 9, 9, e107674.

Research output: Contribution to journalArticle

16 Scopus citations

Hedgehog signaling restrains bladder cancer progression by eliciting stromal production of urothelial differentiation factors

Shin, K., Lim, A., Zhao, C., Sahoo, D., Pan, Y., Spiekerkoetter, E., Liao, J. C. & Beachy, P. A., Oct 13 2014, In : Cancer Cell. 26, 4, p. 521-533 13 p.

Research output: Contribution to journalArticle

84 Scopus citations

Invadopodia Are Required for Cancer Cell Extravasation and Are a Therapeutic Target for Metastasis

Leong, H. S., Robertson, A. E., Stoletov, K., Leith, S. J., Chin, C. A., Chien, A. E., Hague, M. N., Ablack, A., Carmine-Simmen, K., McPherson, V. A., Postenka, C. O., Turley, E. A., Courtneidge, S. A., Chambers, A. F. & Lewis, J. D., Jan 1 2014, In : Cell Reports. 8, 5, p. 1558-1570 13 p.

Research output: Contribution to journalArticle

150 Scopus citations