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2010

MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro

Quintavalle, M., Elia, L., Condorelli, G. & Courtneidge, S. A., Apr 5 2010, In : Journal of Cell Biology. 189, 1, p. 13-22 10 p.

Research output: Contribution to journalArticle

156 Scopus citations

Quantification of three-dimensional cell-mediated collagen remodeling using graph theory

Bilgin, C. C., Lund, A. W., Can, A., Plopper, G. E. & Yener, B., 2010, In : PloS one. 5, 9, p. 1-12 12 p., e12783.

Research output: Contribution to journalArticle

11 Scopus citations

Quantification of vestibular-induced eye movements in zebrafish larvae.

Mo, W., Chen, F., Nechiporuk, A. & Nicolson, T., 2010, In : BMC neuroscience. 11, p. 110 1 p.

Research output: Contribution to journalArticle

42 Scopus citations

Quantitative analysis of three-dimensional human mammary epithelial tissue architecture reveals a role for tenascin-C in regulating c-met function

Taraseviciute, A., Vincent, B. T., Schedin, P. & Jones, P. L., Feb 2010, In : American Journal of Pathology. 176, 2, p. 827-838 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Receptor tyrosine kinase signaling favors a protumorigenic state in breast cancer cells by inhibiting the adaptive immune response

Ursini-Siegel, J., Cory, S., Zuo, D., Hardy, W. R., Rexhepaj, E., Lam, S., Schade, B., Jirstrom, K., Bjur, E., Piccirillo, C. A., DeNardo, D., Coussens, L. M., Brennan, D. J., Gallagher, W. M., Park, M., Pawson, T., Hallett, M. & Muller, W. J., Oct 15 2010, In : Cancer Research. 70, 20, p. 7776-7787 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Regulation of Dpp activity by tissue-specific cleavage of an upstream site within the prodomain

Sopory, S., Kwon, S., Wehrli, M. & Christian, J. L., Oct 2010, In : Developmental Biology. 346, 1, p. 102-112 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Regulation of LIM-domain-binding 1 protein expression by ubiquitination of Lys134

Howard, P. W., Jue, S. F., Ransom, D. G. & Maurer, R. A., Jul 1 2010, In : Biochemical Journal. 429, 1, p. 127-136 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Ricin toxin activates the NALP3 inflammasome

Lindauer, M., Wong, J. & Magun, B., Jun 2010, In : Toxins. 2, 6, p. 1500-1514 15 p.

Research output: Contribution to journalArticle

33 Scopus citations

Stoichiometries of transferrin receptors 1 and 2 in human liver

Chloupková, M., Zhang, A. S. & Enns, C. A., Jan 2010, In : Blood Cells, Molecules, and Diseases. 44, 1, p. 28-33 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Stromal regulation of vessel stability by MMP14 and TGFβ

Sounni, N. E., Dehne, K., Van Kempen, L., Egeblad, M., Affara, N. I., Cuevas, I., Wiesen, J., Junankar, S., Korets, L., Lee, J., Shen, J., Morrison, C. J., Overall, C. M., Krane, S. M., Werb, Z., Boudreau, N. & Coussens, L. M., May 2010, In : DMM Disease Models and Mechanisms. 3, 5-6, p. 317-332 16 p.

Research output: Contribution to journalArticle

57 Scopus citations

The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo

Zhang, A. S., Gao, J., Koeberl, D. D. & Enns, C. A., May 28 2010, In : Journal of Biological Chemistry. 285, 22, p. 16416-16423 8 p.

Research output: Contribution to journalArticle

58 Scopus citations

Transcription intermediary factor 1γ decreases protein expression of the transcriptional cofactor, LIM-domain-binding 1

Howard, P. W., Ransom, D. G. & Maurer, R. A., Jun 4 2010, In : Biochemical and Biophysical Research Communications. 396, 3, p. 674-678 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

ZAK is required for doxorubicin, a novel ribotoxic stressor, to induce SAPK activation and apoptosis in HaCaT cells

Sauter, K. A. D., Magun, E. A., Iordanov, M. S. & Magun, B. E., Aug 1 2010, In : Cancer Biology and Therapy. 10, 3, p. 258-266 9 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

ZRT/IRT-like protein 14 (ZIP14) promotes the cellular assimilation of iron from transferrin

Zhao, N., Gao, J., Enns, C. A. & Knutson, M. D., Oct 15 2010, In : Journal of Biological Chemistry. 285, 42, p. 32141-32150 10 p.

Research output: Contribution to journalArticle

106 Scopus citations
2011

A cell-based high-content screening assay reveals activators and inhibitors of cancer cell invasion

Quintavalle, M., Elia, L., Price, J. H., Heynen-Genel, S. & Courtneidge, S. A., Jul 26 2011, In : Science signaling. 4, 183, ra49.

Research output: Contribution to journalArticle

71 Scopus citations

A MEK-independent role for CRAF in mitosis and tumor progression

Mielgo, A., Seguin, L., Huang, M., Camargo, M. F., Anand, S., Franovic, A., Weis, S. M., Advani, S. J., Murphy, E. A. & Cheresh, D. A., Dec 2011, In : Nature medicine. 17, 12, p. 1641-1645 5 p.

Research output: Contribution to journalArticle

40 Scopus citations
2 Scopus citations

A Src-Tks5 pathway is required for neural crest cell migration during embryonic development

Murphy, D. A., Diaz, B., Bromann, P. A., Tsai, J. H., Kawakami, Y., Maurer, J., Stewart, R. A., Izpisúa-Belmonte, J. C. & Courtneidge, S. A., 2011, In : PloS one. 6, 7, e22499.

Research output: Contribution to journalArticle

59 Scopus citations

A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: Isradipine as a candidate drug

Copenhaver, P. F., Anekonda, T. S., Musashe, D., Robinson, K. M., Ramaker, J. M., Swanson, T. L., Wadsworth, T. L., Kretzschmar, D., Woltjer, R. L. & Quinn, J. F., Sep 2011, In : DMM Disease Models and Mechanisms. 4, 5, p. 634-648 15 p.

Research output: Contribution to journalArticle

25 Scopus citations

B regulatory cells and the tumor-promoting actions of TNF-α during squamous carcinogenesis

Schioppa, T., Moore, R., Thompson, R. G., Rosser, E. C., Kulbe, H., Nedospasov, S., Mauri, C., Coussens, L. M. & Balkwill, F. R., Jun 28 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 26, p. 10662-10667 6 p.

Research output: Contribution to journalArticle

186 Scopus citations

Chondrogenic and gliogenic subpopulations of neural crest play distinct roles during the assembly of epibranchial ganglia

Culbertson, M. D., Lewis, Z. R. & Nechiporuk, A. V., Sep 9 2011, In : PloS one. 6, 9, e24443.

Research output: Contribution to journalArticle

13 Scopus citations

Clusterin induces matrix metalloproteinase-9 expression via ERK1/2 and PI3K/Akt/NF-κB pathways in monocytes/macrophages

Shim, Y. J., Kang, B. H., Jeon, H. S., Park, I. S., Lee, K. U., Lee, I. K., Park, G. H., Lee, K. M., Schedin, P. & Min, B. H., Oct 1 2011, In : Journal of Leukocyte Biology. 90, 4, p. 761-769 9 p.

Research output: Contribution to journalArticle

54 Scopus citations

Doxorubicin and daunorubicin induce processing and release of interleukin-1β through activation of the NLRP3 inflammasome

Sauter, K. A. D., Wood, L. J., Wong, J., Iordanov, M. & Magun, B. E., Jun 15 2011, In : Cancer Biology and Therapy. 11, 12, p. 1008-1016 9 p.

Research output: Contribution to journalArticle

93 Scopus citations

Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models

Cheong, J. H., Park, E. S., Liang, J., Dennison, J. B., Tsavachidou, D., Nguyen-Charles, C., Cheng, K. W., Hall, H., Zhang, D., Lu, Y., Ravoori, M., Kundra, V., Ajani, J., Lee, J. S., Hong, W. K. & Mills, G. B., Dec 2011, In : Molecular cancer therapeutics. 10, 12, p. 2350-2362 13 p.

Research output: Contribution to journalArticle

163 Scopus citations

Emerging Role of Micro-RNAs in the Regulation of Angiogenesis

Anand, S. & Cheresh, D. A., Dec 2011, In : Genes and Cancer. 2, 12, p. 1134-1138 5 p.

Research output: Contribution to journalArticle

30 Scopus citations

Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder

Shin, K., Lee, J., Guo, N., Kim, J., Lim, A., Qu, L., Mysorekar, I. U. & Beachy, P. A., Apr 7 2011, In : Nature. 472, 7341, p. 110-116 7 p.

Research output: Contribution to journalArticle

261 Scopus citations

Herpesvirus entry mediator regulates hypoxiainducible factor-1α and erythropoiesis in mice

Sakoda, Y., Anand, S., Zhao, Y., Park, J. J., Liu, Y., Kuramasu, A., Van Rooijen, N., Chen, L., Strome, S. E., Hancock, W. W., Chen, L. & Tamada, K., Dec 1 2011, In : Journal of Clinical Investigation. 121, 12, p. 4810-4819 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Histamine restricts cancer: Nothing to sneeze at

Ruffell, B. & Coussens, L. M., Jan 1 2011, In : Nature medicine. 17, 1, p. 43-44 2 p.

Research output: Contribution to journalArticle

11 Scopus citations

Immune microenvironments in solid tumors: New targets for therapy

Shiao, S. L., Preethi Ganesan, A., Rugo, H. S. & Coussens, L. M., Dec 15 2011, In : Genes and Development. 25, 24, p. 2559-2572 14 p.

Research output: Contribution to journalArticle

206 Scopus citations

Lef1 is required for progenitor cell identity in the zebrafish lateral line primordium

McGraw, H. F., Drerup, C. M., Culbertson, M. D., Linbo, T., Raible, D. W. & Nechiporuk, A. V., Sep 15 2011, In : Development. 138, 18, p. 3921-3930 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

DeNardo, D. G., Brennan, D. J., Rexhepaj, E., Ruffell, B., Shiao, S. L., Madden, S. F., Gallagher, W. M., Wadhwani, N., Keil, S. D., Junaid, S. A., Rugo, H. S., Shelley Hwang, E., Jirström, K., West, B. L. & Coussens, L. M., Jun 2011, In : Cancer discovery. 1, 1, p. 54-67 14 p.

Research output: Contribution to journalArticle

941 Scopus citations

Leukocytes as paracrine regulators of metastasis and determinants of organ-specific colonization

Erez, N. & Coussens, L. M., Jun 1 2011, In : International Journal of Cancer. 128, 11, p. 2536-2544 9 p.

Research output: Contribution to journalArticle

43 Scopus citations

Leukocytes in mammary development and cancer

Coussens, L. M. & Pollard, J. W., Mar 2011, In : Cold Spring Harbor Perspectives in Biology. 3, 3, p. 1-22 22 p.

Research output: Contribution to journalArticle

101 Scopus citations
229 Scopus citations

MicroRNA-mediated regulation of the angiogenic switch

Anand, S. & Cheresh, D. A., May 2011, In : Current opinion in hematology. 18, 3, p. 171-176 6 p.

Research output: Contribution to journalArticle

47 Scopus citations

MRI of tumor-associated macrophages with clinically applicable iron oxide nanoparticles

Daldrup-Link, H. E., Golovko, D., Ruffell, B., DeNardo, D. G., Castaneda, R., Ansari, C., Rao, J., Tikhomirov, G. A., Wendland, M. F., Corot, C. & Coussens, L. M., Sep 1 2011, In : Clinical Cancer Research. 17, 17, p. 5695-5704 10 p.

Research output: Contribution to journalArticle

173 Scopus citations

Non-steroidal anti-inflammatory drugs target the pro-tumorigenic extracellular matrix of the postpartum mammary gland

O'Brien, J., Hansen, K., Barkan, D., Green, J. & Schedin, P., 2011, In : International Journal of Developmental Biology. 55, 7-9, p. 745-755 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Paneth cell marker expression in intestinal villi and colon crypts characterizes dietary induced risk for mouse sporadic intestinal cancer

Wang, D., Peregrina, K., Dhima, E., Lin, E. Y., Mariadason, J. M. & Augenlicht, L. H., Jun 21 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 25, p. 10272-10277 6 p.

Research output: Contribution to journalArticle

31 Scopus citations

Platelet indices in diabetes mellitus: Indicators of diabetic microvascular complications

Jindal, S., Gupta, S., Gupta, R., Kakkar, A., Singh, H. V., Gupta, K. & Singh, S., Mar 1 2011, In : Hematology. 16, 2, p. 86-89 4 p.

Research output: Contribution to journalArticle

82 Scopus citations

Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2

Lyons, T. R., O'Brien, J., Borges, V. F., Conklin, M. W., Keely, P. J., Eliceiri, K. W., Marusyk, A., Tan, A. C. & Schedin, P., Sep 2011, In : Nature medicine. 17, 9, p. 1109-1116 8 p.

Research output: Contribution to journalArticle

199 Scopus citations

Sortilin associates with transforming growth factor-β family proteins to enhance lysosome-mediated degradation

Kwon, S. & Christian, J. L., Jun 17 2011, In : Journal of Biological Chemistry. 286, 24, p. 21876-21885 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Suppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 protein

Zhang, A. S., Anderson, S. A., Wang, J., Yang, F., DeMaster, K., Ahmed, R., Nizzi, C. P., Eisenstein, R. S., Tsukamoto, H. & Enns, C. A., Feb 3 2011, In : Blood. 117, 5, p. 1687-1899 213 p.

Research output: Contribution to journalArticle

72 Scopus citations

T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse

Moran, A. E., Holzapfel, K. L., Xing, Y., Cunningham, N. R., Maltzman, J. S., Punt, J. & Hogquist, K. A., Jun 2011, In : Journal of Experimental Medicine. 208, 6, p. 1279-1289 11 p.

Research output: Contribution to journalArticle

Open Access
519 Scopus citations

The Bcl-2 repertoire of mesothelioma spheroids underlies acquired apoptotic multicellular resistance

Barbone, D., Ryan, J. A., Kolhatkar, N., Chacko, A. D., Jablons, D. M., Sugarbaker, D. J., Bueno, R., Letai, A. G., Coussens, L. M., Fennell, D. A. & Broaddus, V. C., Jun 2011, In : Cell Death and Disease. 2, 6, e174.

Research output: Contribution to journalArticle

32 Scopus citations

Unimpeded skin carcinogenesis in K14-HPV16 transgenic mice deficient for plasminogen activator inhibitor

Masset, A., Maillard, C., Sounni, N. E., Jacobs, N., Bruyére, F., Delvenne, P., Tacke, M., Reinheckel, T., Foidart, J. M., Coussens, L. M. & Noaël, A., Jan 15 2011, In : International Journal of Cancer. 128, 2, p. 283-293 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Zebrafish mnx1 controls cell fate choice in the developing endocrine pancreas

Dalgin, G., Ward, A. B., Hao, L. T., Beattie, C. E., Nechiporuk, A. & Prince, V. E., Nov 1 2011, In : Development. 138, 21, p. 4597-4608 12 p.

Research output: Contribution to journalArticle

40 Scopus citations
2012

Alterations in mast cell frequency and relationship to angiogenesis in the rat mammary gland during windows of physiologic tissue remodeling

Ramirez, R. A., Lee, A., Schedin, P., Russell, J. S. & Masso-Welch, P. A., May 2012, In : Developmental Dynamics. 241, 5, p. 890-900 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Annexin A5 binds to lipopolysaccharide and reduces its endotoxin activity

Rand, J. H., Wu, X. X., Lin, E. Y., Griffel, A., Gialanella, P. & McKitrick, J. C., 2012, In : mBio. 3, 2, e00292-11.

Research output: Contribution to journalArticle

29 Scopus citations

An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration

Chen, T., Heller, E., Beronja, S., Oshimori, N., Stokes, N. & Fuchs, E., May 3 2012, In : Nature. 485, 7396, p. 104-108 5 p.

Research output: Contribution to journalArticle

71 Scopus citations

Antigen-independent differentiation and maintenance of effector-like resident memory T Cells in tissues

Casey, K. A., Fraser, K. A., Schenkel, J. M., Moran, A., Abt, M. C., Beura, L. K., Lucas, P. J., Artis, D., Wherry, E. J., Hogquist, K., Vezys, V. & Masopust, D., May 15 2012, In : Journal of Immunology. 188, 10, p. 4866-4875 10 p.

Research output: Contribution to journalArticle

288 Scopus citations