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2009
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42 Scopus citations

Development of an optimized activatable MMP-14 targeted SPECT imaging probe

Watkins, G. A., Jones, E. F., Scott Shell, M., VanBrocklin, H. F., Pan, M. H., Hanrahan, S. M., Feng, J. J., He, J., Sounni, N. E., Dill, K. A., Contag, C. H., Coussens, L. M. & Franc, B. L., Jan 15 2009, In : Bioorganic and Medicinal Chemistry. 17, 2, p. 653-659 7 p.

Research output: Contribution to journalArticle

44 Scopus citations

Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia

Chen, S. S., Raval, A., Johnson, A. J., Hertlein, E., Liua, T. H., Jin, V. X., Sherman, M. H., Liu, S. J., Dawson, D. W., Williams, K. E., Lanasa, M., Liyanarachchi, S., Lin, T. S., Marcucci, G., Pekarsky, Y., Davuluri, R., Croce, C. M., Guttridge, D. C., Teitell, M. A., Byrd, J. C. & 1 others, Plass, C., Aug 11 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 32, p. 13433-13438 6 p.

Research output: Contribution to journalArticle

70 Scopus citations

Epigenetic silencing of Stk39 in B-cell lymphoma inhibits apoptosis from genotoxic stress

Balatoni, C. E., Dawson, D. W., Suh, J., Sherman, M. H., Sanders, G., Hong, J. S., Frank, M. J., Malone, C. S., Said, J. W. & Teitell, M. A., 2009, In : American Journal of Pathology. 175, 4, p. 1653-1661 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Expression of the synaptotagmin I gene is enhanced by binding of the pituitary-specific transcription factor, POU1F1

Howard, P. W., Jue, S. F. & Maurer, R. A., 2009, In : Molecular Endocrinology. 23, 10, p. 1563-1571 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Hemojuvelin-neogenin interaction is required for bone morphogenic protein-4-induced hepcidin expression

Zhang, A. S., Yang, F., Wang, J., Tsukamoto, H. & Enns, C. A., Aug 21 2009, In : Journal of Biological Chemistry. 284, 34, p. 22580-22589 10 p.

Research output: Contribution to journalArticle

60 Scopus citations

Identifying significant temporal variation in time course microarray data without replicates

Billups, S. C., Neville, M. C., Rudolph, M., Porter, W. & Schedin, P., Mar 26 2009, In : BMC bioinformatics. 10, 96.

Research output: Contribution to journalArticle

11 Scopus citations

Inhibition of ERK promotes collagen gel compaction and fibrillogenesis to amplify the osteogenesis of human mesenchymal stem cells in three-dimensional collagen I culture

Lund, A. W., Stegemann, J. P. & Plopper, G. E., Mar 1 2009, In : Stem Cells and Development. 18, 2, p. 331-341 11 p.

Research output: Contribution to journalArticle

39 Scopus citations

Interaction of the Hereditary Hemochromatosis Protein HFE with Transferrin Receptor 2 Is Required for Transferrin-Induced Hepcidin Expression

Gao, J., Chen, J., Kramer, M., Tsukamoto, H., Zhang, A. S. & Enns, C. A., Mar 4 2009, In : Cell Metabolism. 9, 3, p. 217-227 11 p.

Research output: Contribution to journalArticle

213 Scopus citations

Lung tumor promotion by curcumin

Dance-Barnes, S. T., Kock, N. D., Moore, J. E., Lin, E. Y., Mosley, L. J., D'Agostino, R. B., Mccoy, T. P., Townsend, A. J. & Miller, M. S., 2009, In : Carcinogenesis. 30, 6, p. 1016-1023 8 p.

Research output: Contribution to journalArticle

61 Scopus citations
50 Scopus citations

Mitogen-activated protein kinase-activated kinase RSK2 plays a role in innate immune responses to influenza virus infection

Kakugawa, S., Shimojima, M., Goto, H., Horimoto, T., Oshimori, N., Neumann, G., Yamamoto, T. & Kawaoka, Y., Mar 2009, In : Journal of virology. 83, 6, p. 2510-2517 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation

Stylli, S. S., Stacey, T. T. I., Verhagen, A. M., Xu, S. S., Pass, I., Courtneidge, S. A. & Lock, P., Aug 1 2009, In : Journal of Cell Science. 122, 15, p. 2727-2740 14 p.

Research output: Contribution to journalArticle

86 Scopus citations

Novel p47phox-related organizers regulate localized NADPH oxidase 1 (Nox1) activity

Gianni, D., Diaz, B., Taulet, N., Fowler, B., Courtneidge, S. A. & Bokoch, G. M., Sep 15 2009, In : Science signaling. 2, 88, p. ra54

Research output: Contribution to journalArticle

68 Scopus citations

Optical imaging of the peri-tumoral inflammatory response in breast cancer

Sista, A. K., Knebel, R. J., Tavri, S., Johansson, M., DeNardo, D. G., Boddington, S. E., Kishore, S. A., Ansari, C., Reinhart, V., Coakley, F. V., Coussens, L. M. & Daldrup-Link, H. E., Nov 11 2009, In : Journal of translational medicine. 7, 94.

Research output: Contribution to journalArticle

6 Scopus citations

Pregnancy and breast cancer: When they collide

Lyons, T. R., Schedin, P. J. & Borges, V. F., 2009, In : Journal of Mammary Gland Biology and Neoplasia. 14, 2, p. 87-98 12 p.

Research output: Contribution to journalArticle

119 Scopus citations

Processing of hemojuvelin requires retrograde trafficking to the Golgi in HepG2 cells

Maxson, J. E., Enns, C. A. & Zhang, A. S., Feb 19 2009, In : Blood. 113, 8, p. 1786-1793 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Quantification of spatial parameters in 3D cellular constructs using graph theory

Lund, A. W., Bilgin, C. C., Hasan, M. A., McKeen, L. M., Stegemann, J. P., Yener, B., Zaki, M. J. & Plopper, G. E., 2009, In : Journal of Biomedicine and Biotechnology. 2009, 928286.

Research output: Contribution to journalArticle

8 Scopus citations

Reverse signaling by glycosylphosphatidylinositol-linked manduca ephrin requires a src family kinase to restrict neuronal migration in vivo

Coate, T. M., Swanson, T. L. & Copenhaver, P. F., Mar 18 2009, In : Journal of Neuroscience. 29, 11, p. 3404-3418 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

Site-specific cleavage of BMP4 by furin, PC6, and PC7

Nelsen, S. M. & Christian, J. L., Oct 2 2009, In : Journal of Biological Chemistry. 284, 40, p. 27157-27166 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

Tamoxifen induces pleiotrophic changes in mammary stroma resulting in extracellular matrix that suppresses transformed phenotypes

Hattar, R., Maller, O., McDaniel, S., Hansen, K. C., Hedman, K. J., Lyons, T. R., Lucia, S., Wilson, R. S. & Schedin, P., Jan 27 2009, In : Breast Cancer Research. 11, 1, R5.

Research output: Contribution to journalArticle

45 Scopus citations

Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: Implications for psoriasis pathogenesis

Harper, E. G., Guo, C., Rizzo, H., Lillis, J. V., Kurtz, S. E., Skorcheva, I., Purdy, D., Fitch, E., Iordanov, M. & Blauvelt, A., Sep 2009, In : Journal of Investigative Dermatology. 129, 9, p. 2175-2183 9 p.

Research output: Contribution to journalArticle

280 Scopus citations

The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: Correlates with human disease

Elia, L., Quintavalle, M., Zhang, J., Contu, R., Cossu, L., Latronico, M. V. G., Peterson, K. L., Indolfi, C., Catalucci, D., Chen, J., Courtneidge, S. A. & Condorelli, G., 2009, In : Cell Death and Differentiation. 16, 12, p. 1590-1598 9 p.

Research output: Contribution to journalArticle

398 Scopus citations

The novel adaptor protein tks4 (SH3PXD2B) is required for functional podosome formation

Buschman, M. D., Bromann, P. A., Cejudo-Martin, P., Wen, F., Pass, I. & Courtneidge, S. A., Mar 1 2009, In : Molecular biology of the cell. 20, 5, p. 1302-1311 10 p.

Research output: Contribution to journalArticle

106 Scopus citations

Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation

Diaz, B., Shani, G., Pass, I., Anderson, D., Quintavalle, M. & Courtneidge, S. A., Sep 15 2009, In : Science signaling. 2, 88, p. ra53

Research output: Contribution to journalArticle

155 Scopus citations

Tks5 recruits AFAP-110, p190RhoGAP, and cortactin for podosome formation

Crimaldi, L., Courtneidge, S. A. & Gimona, M., Sep 10 2009, In : Experimental Cell Research. 315, 15, p. 2581-2592 12 p.

Research output: Contribution to journalArticle

41 Scopus citations

Transferrin-directed internalization and cycling of transferrin receptor 2

Chen, J., Wang, J., Meyers, K. R. & Enns, C. A., Oct 2009, In : Traffic. 10, 10, p. 1488-1501 14 p.

Research output: Contribution to journalArticle

38 Scopus citations

Treg cells meet their limit

Hogquist, K. A. & Moran, A. E., May 28 2009, In : Nature Immunology. 10, 6, p. 565-566 2 p.

Research output: Contribution to journalArticle

4 Scopus citations

Western-style diets induce oxidative stress and dysregulate immune responses in the colon in a mouse model of sporadic colon cancer

Erdelyi, I., Levenkova, N., Lin, E. Y., Pinto, J. T., Lipkin, M., Quimby, F. W. & Holt, P. R., Nov 2009, In : Journal of Nutrition. 139, 11, p. 2072-2078 7 p.

Research output: Contribution to journalArticle

58 Scopus citations
2010

AID-induced genotoxic stress promotes B cell differentiation in the germinal center via ATM and LKB1 signaling

Sherman, M. H., Kuraishy, A. I., Deshpande, C., Hong, J. S., Cacalano, N. A., Gatti, R. A., Manis, J. P., Damore, M. A., Pellegrini, M. & Teitell, M. A., Sep 2010, In : Molecular Cell. 39, 6, p. 873-885 13 p.

Research output: Contribution to journalArticle

52 Scopus citations

Alternatively activated macrophages and collagen remodeling characterize the postpartum involuting mammary gland across species

O'Brien, J., Lyons, T., Monks, J., Lucia, M. S., Wilson, R. S., Hines, L., Man, Y. G., Borges, V. & Schedin, P., Mar 2010, In : American Journal of Pathology. 176, 3, p. 1241-1255 15 p.

Research output: Contribution to journalArticle

141 Scopus citations

A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis

Deng, L., Zhou, J. F., Sellers, R. S., Li, J. F., Nguyen, A. V., Wang, Y., Orlofsky, A., Liu, Q., Hume, D. A., Pollard, J. W., Augenlicht, L. & Lin, E. Y., Feb 2010, In : American Journal of Pathology. 176, 2, p. 952-967 16 p.

Research output: Contribution to journalArticle

127 Scopus citations

A surprising link between the energetics of ovariectomy-induced weight gain and mammary tumor progression in obese rats

MacLean, P. S., Giles, E. D., Johnson, G. C., McDaniel, S. M., Fleming-Elder, B. K., Gilman, K. A., Andrianakos, A. G., Jackman, M. R., Shroyer, K. R. & Schedin, P. J., Apr 2010, In : Obesity. 18, 4, p. 696-703 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance

Park, J. J., Omiya, R., Matsumura, Y., Sakoda, Y., Kuramasu, A., Augustine, M. M., Yao, S., Tsushima, F., Narazaki, H., Anand, S., Liu, Y., Strome, S. E., Chen, L. & Tamada, K., Aug 26 2010, In : Blood. 116, 8, p. 1291-1298 8 p.

Research output: Contribution to journalArticle

202 Scopus citations

Benign mammary epithelial cells enhance the transformed phenotype of human breast cancer cells

Poczobutt, J. M., Tentler, J., Lu, X., Schedin, P. J. & Gutierrez-Hartmann, A., Jul 16 2010, In : BMC cancer. 10, 373.

Research output: Contribution to journalArticle

11 Scopus citations

Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis

Dennemärker, J., Lohmüller, T., Mayerle, J., Tacke, M., Lerch, M. M., Coussens, L. M., Peters, C. & Reinheckel, T., Mar 2010, In : Oncogene. 29, 11, p. 1611-1621 11 p.

Research output: Contribution to journalArticle

74 Scopus citations

Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRβ/B-RAF

Murphy, E. A., Shields, D. J., Stoletov, K., Dneprovskaia, E., McElroy, M., Greenberg, J. I., Lindquist, J., Acevedo, L. M., Anand, S., Majeti, B. K., Tsigelny, I., Saldanha, A., Walsh, B., Hoffman, R. M., Bouvet, M., Klemke, R. L., Vogt, P. K., Arnold, L., Wrasidlo, W. & Cheresh, D. A., Mar 2 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 9, p. 4299-4304 6 p.

Research output: Contribution to journalArticle

42 Scopus citations

Disruption of the Podosome Adaptor Protein TKS4 (SH3PXD2B) Causes the Skeletal Dysplasia, Eye, and Cardiac Abnormalities of Frank-Ter Haar Syndrome

Iqbal, Z., Cejudo-Martin, P., de Brouwer, A., van der Zwaag, B., Ruiz-Lozano, P., Scimia, M. C., Lindsey, J. D., Weinreb, R., Albrecht, B., Megarbane, A., Alanay, Y., Ben-Neriah, Z., Amenduni, M., Artuso, R., Veltman, J. A., van Beusekom, E., Oudakker, A., Millán, J. L., Hennekam, R., Hamel, B. & 2 others, Courtneidge, S. A. & van Bokhoven, H., Feb 12 2010, In : American Journal of Human Genetics. 86, 2, p. 254-261 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Effect of the estrous cycle and surgical ovariectomy on energy balance, fuel utilization, and physical activity in lean and obese female rats

Giles, E. D., Jackman, M. R., Johnson, G. C., Schedin, P. J., Houser, J. L. & MacLean, P. S., Dec 2010, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 299, 6, p. R1634-R1642

Research output: Contribution to journalArticle

25 Scopus citations

EMX2 is epigenetically silenced and suppresses growth in human lung cancer

Okamoto, J., Hirata, T., Chen, Z., Zhou, H. M., Mikami, I., Li, H., Beltran, A., Johansson, M., Coussens, L. M., Clement, G., Shi, Y., Zhang, F., Koizumi, K., Shimizu, K., Jablons, D. & He, B., Nov 4 2010, In : Oncogene. 29, 44, p. 5969-5975 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Enhancing the delivery of anti retroviral drug "saquinavir" across the blood brain barrier using nanoparticles

Mahajan, S. D., Roy, I., Xu, G. X., Yong, K. T., Ding, H., Aalinkeel, R., Reynolds, J. L., Sykes, D. E., Nair, B. B., Lin, E. Y., Prasad, P. N. & Schwartz, S. A., 2010, In : Current HIV Research. 8, 5, p. 396-404 9 p.

Research output: Contribution to journalArticle

71 Scopus citations

FcRγ Activation Regulates Inflammation-Associated Squamous Carcinogenesis

Andreu, P., Johansson, M., Affara, N. I., Pucci, F., Tan, T., Junankar, S., Korets, L., Lam, J., Tawfik, D., DeNardo, D. G., Naldini, L., de Visser, K. E., De Palma, M. & Coussens, L. M., Feb 17 2010, In : Cancer Cell. 17, 2, p. 121-134 14 p.

Research output: Contribution to journalArticle

334 Scopus citations

Gelatin microspheres crosslinked with genipin for local delivery of growth factors.

Solorio, L., Zwolinski, C., Lund, A. W., Farrell, M. J. & Stegemann, J. P., Oct 2010, In : Journal of tissue engineering and regenerative medicine. 4, 7, p. 514-523 10 p.

Research output: Contribution to journalArticle

100 Scopus citations

Generation of mice with a conditional allele for Ift172

Howard, P. W., Howard, T. L. & Maurer, R. A., Jan 2010, In : Transgenic Research. 19, 1, p. 121-126 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice

Gao, J., Chen, J., De Domenico, I., Koeller, D. M., Harding, C. O., Fleming, R. E., Koeberl, D. D. & Enns, C. A., Apr 22 2010, In : Blood. 115, 16, p. 3374-3381 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Lymphocytes in cancer development: Polarization towards pro-tumor immunity

Ruffell, B., DeNardo, D. G., Affara, N. I. & Coussens, L. M., Feb 2010, In : Cytokine and Growth Factor Reviews. 21, 1, p. 3-10 8 p.

Research output: Contribution to journalArticle

130 Scopus citations

Macrophage expression of hypoxia-inducible factor-1α suppresses T-cell function and promotes tumor progression

Doedens, A. L., Stockmann, C., Rubinstein, M. P., Liao, D., Zhang, N., DeNardo, D. G., Coussens, L. M., Karin, M., Goldrath, A. W. & Johnson, R. S., Oct 1 2010, In : Cancer Research. 70, 19, p. 7465-7475 11 p.

Research output: Contribution to journalArticle

312 Scopus citations
49 Scopus citations

Mechanosensitive Hair Cell-like Cells from Embryonic and Induced Pluripotent Stem Cells

Oshima, K., Shin, K., Diensthuber, M., Peng, A. W., Ricci, A. J. & Heller, S., May 2010, In : Cell. 141, 4, p. 704-716 13 p.

Research output: Contribution to journalArticle

209 Scopus citations

MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis

Anand, S., Majeti, B. K., Acevedo, L. M., Murphy, E. A., Mukthavaram, R., Scheppke, L., Huang, M., Shields, D. J., Lindquist, J. N., Lapinski, P. E., King, P. D., Weis, S. M. & Cheresh, D. A., Aug 2010, In : Nature medicine. 16, 8, p. 909-914 6 p.

Research output: Contribution to journalArticle

387 Scopus citations