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2006

Macrophages regulate the angiogenic switch in a mouse model of breast cancer

Lin, E. Y., Li, J. F., Gnatovskiy, L., Deng, Y., Zhu, L., Grzesik, D. A., Qian, H., Xue, X. N. & Pollard, J. W., Dec 1 2006, In : Cancer Research. 66, 23, p. 11238-11246 9 p.

Research output: Contribution to journalArticle

675 Scopus citations
Open Access
13 Scopus citations

Regulation of bone morphogenetic protein-4 activity by sequence elements within the prodomain

Sopory, S., Nelsen, S. M., Degnin, C., Wong, C. & Christian, J. L., Nov 10 2006, In : Journal of Biological Chemistry. 281, 45, p. 34021-34031 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

Remodeling of the mammary microenvironment after lactation promotes breast tumor cell metastasis

McDaniel, S. M., Rumer, K. K., Biroc, S. L., Metz, R. P., Singh, M., Porter, W. & Schedin, P., Feb 2006, In : American Journal of Pathology. 168, 2, p. 608-620 13 p.

Research output: Contribution to journalArticle

143 Scopus citations

Sustained Bmp signaling is essential for cloaca development in zebrafish

Pyati, U. J., Cooper, M. S., Davidson, A. J., Nechiporuk, A. & Kimelman, D., Jun 1 2006, In : Development. 133, 11, p. 2275-2284 10 p.

Research output: Contribution to journalArticle

70 Scopus citations

The anemia of "haemoglobin-deficit" (hbd/hbd) mice is caused by a defect in transferrin cycling

Zhang, A. S., Sheftel, A. D. & Ponka, P., May 1 2006, In : Experimental hematology. 34, 5, p. 593-598 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

The Plk1 target Kizuna stabilizes mitotic centrosomes to ensure spindle bipolarity

Oshimori, N., Ohsugi, M. & Yamamoto, T., Oct 2006, In : Nature Cell Biology. 8, 10, p. 1095-1101 7 p.

Research output: Contribution to journalArticle

109 Scopus citations

Tumor progression and metastasis from genetic to microenvironmental determinants: A Workshop of the Tumor Progression and Metastasis NIH Study Section in Honor of Dr. Martin L. Padarathsingh, May 31, 2006, Georgetown, Washington, DC

De Clerck, Y. A., Weissman, B. E., Yu, D., Parsons, R., Bar-Eli, M., Roy-Burman, P., Seewaldt, V. L., Cress, A. E., Languino, L. R., Batra, S. K., Tang, C. K., Sheng, S., Chen, W. T., Chellappan, S., Cheng, S. Y., Ladisch, S., McCarthy, J. B., Coussens, L. M. & Cohen, M. B., Dec 2006, In : Cancer Biology and Therapy. 5, 12, p. 1588-1599 12 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2007

An inducible system for expression and validation of the specificity of short hairpin RNA in mammalian cells

Ma, H. T., On, K. F., Tsang, Y. H. & Poon, R. Y. C., Feb 2007, In : Nucleic acids research. 35, 4, e22.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Direct interorganellar transfer of iron from endosome to mitochondrion

Sheftel, A. D., Zhang, A. S., Brown, C., Shirihai, O. S. & Ponka, P., Jul 1 2007, In : Blood. 110, 1, p. 125-132 8 p.

Research output: Contribution to journalArticle

176 Scopus citations

Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors

Wyckoff, J. B., Wang, Y., Lin, E. Y., Li, J. F., Goswami, S., Stanley, E. R., Segall, J. E., Pollard, J. W. & Condeelis, J., Mar 15 2007, In : Cancer Research. 67, 6, p. 2649-2656 8 p.

Research output: Contribution to journalArticle

667 Scopus citations

Distinctive features of angiogenesis and lymphangiogenesis determine their functionality during de novo tumor development

Eichten, A., Hyun, W. C. & Coussens, L. M., Jun 1 2007, In : Cancer Research. 67, 11, p. 5211-5220 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Eph receptor expression defines midline boundaries for ephrin-positive migratory neurons in the enteric nervous system of Manduca sexta

Coate, T. M., Swanson, T. L., Proctor, T. M., Nighorn, A. J. & Copenhaver, P. F., May 10 2007, In : Journal of Comparative Neurology. 502, 2, p. 175-191 17 p.

Research output: Contribution to journalArticle

8 Scopus citations

Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin

Zhang, A. S., Anderson, S. A., Meyers, K. R., Hernandez, C., Eisenstein, R. S. & Enns, C. A., Apr 27 2007, In : Journal of Biological Chemistry. 282, 17, p. 12547-12556 10 p.

Research output: Contribution to journalArticle

92 Scopus citations

HFE modulates transferrin receptor 2 levels in hepatoma cells via interactions that differ from transferrin receptor 1-HFE interactions

Chen, J., Chloupková, M., Gao, J., Chapman-Arvedson, T. L. & Enns, C. A., Dec 21 2007, In : Journal of Biological Chemistry. 282, 51, p. 36862-36870 9 p.

Research output: Contribution to journalArticle

69 Scopus citations

Hu/Mu protin oligonucleotide microarray: Dual-species array for profiling protease and protease inhibitor gene expression in tumors and their microenvironment

Schwartz, D. R., Moin, K., Yao, B., Matrisian, L. M., Coussens, L. M., Bugge, T. H., Fingleton, B., Acuff, H. B., Sinnamon, M., Nassar, H., Platts, A. E., Krawetz, S. A., Linebaugh, B. E. & Sloane, B. F., May 2007, In : Molecular Cancer Research. 5, 5, p. 443-454 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Inhibition of breast cancer growth and invasion by single-minded 2s

Kwak, H. I., Gustafson, T., Metz, R. P., Laffin, B., Schedin, P. & Porter, W. W., Feb 1 2007, In : Carcinogenesis. 28, 2, p. 259-266 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

Intrapulmonary delivery of ricin at high dosage triggers a systemic inflammatory response and glomerular damage

Wong, J., Korcheva, V., Jacoby, D. B. & Magun, B., May 2007, In : American Journal of Pathology. 170, 5, p. 1497-1510 14 p.

Research output: Contribution to journalArticle

42 Scopus citations

PATJ regulates directional migration of mammalian epithelial cells

Shin, K., Wang, Q. & Margolis, B., Feb 2007, In : EMBO Reports. 8, 2, p. 158-164 7 p.

Research output: Contribution to journalArticle

58 Scopus citations

Role of apoptotic signaling pathways in regulation of inflammatory responses to ricin in primary murine macrophages

Korcheva, V., Wong, J., Lindauer, M., Jacoby, D. B., Iordanov, M. S. & Magun, B., Apr 2007, In : Molecular Immunology. 44, 10, p. 2761-2771 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

Selective targeting of the LIGHT-HVEM costimulatory system for the treatment of graft-versus-host disease

Xu, Y., Flies, A. S., Flies, D. B., Zhu, G., Anand, S., Flies, S. J., Xu, H., Anders, R. A., Hancock, W. W., Chen, L. & Tamada, K., May 1 2007, In : Blood. 109, 9, p. 4097-4104 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

Specification of epibranchial placodes in zebrafish

Nechiporuk, A., Linbo, T., Poss, K. D. & Raible, D. W., Feb 1 2007, In : Development. 134, 3, p. 611-623 13 p.

Research output: Contribution to journalArticle

82 Scopus citations

The cytoplasmic domain of transferrin receptor 2 dictates its stability and response to holo-transferrin in Hep3B cells

Chen, J. & Enns, C. A., Mar 2 2007, In : Journal of Biological Chemistry. 282, 9, p. 6201-6209 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Tissue inhibitor of metalloproteinases-1 promotes liver metastasis by induction of hepatocyte growth factor signaling

Kopitz, C., Gerg, M., Bandapalli, O. R., Ister, D., Pennington, C. J., Hauser, S., Flechsig, C., Krell, H. W., Antolovic, D., Brew, K., Nagase, H., Stangl, M., Hann Von Weyhern, C. W., Brücher, B. L. D. M., Brand, K., Coussens, L. M., Edwards, D. R. & Krüger, A., Sep 15 2007, In : Cancer Research. 67, 18, p. 8615-8623 9 p.

Research output: Contribution to journalArticle

114 Scopus citations

TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformation

Kuraishy, A. I., French, S. W., Sherman, M., Herling, M., Jones, D., Wall, R. & Teitell, M. A., Jun 12 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 24, p. 10175-10180 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Transferrin receptor 2: Evidence for ligand-induced stabilization and redirection to a recycling pathway

Johnson, M. B., Chen, J., Murchison, N., Green, F. A. & Enns, C. A., Mar 2007, In : Molecular biology of the cell. 18, 3, p. 743-754 12 p.

Research output: Contribution to journalArticle

73 Scopus citations

Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development

Egeblad, M., Shen, H. C. J., Behonick, D. J., Wilmes, L., Eichten, A., Korets, L. V., Kheradmand, F., Werb, Z. & Coussens, L. M., Jun 2007, In : Developmental Dynamics. 236, 6, p. 1683-1693 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages

Lin, E. Y., Li, J. F., Bricard, G., Wang, W., Deng, Y., Sellers, R., Porcelli, S. A. & Pollard, J. W., Dec 2007, In : Molecular Oncology. 1, 3, p. 288-302 15 p.

Research output: Contribution to journalArticle

114 Scopus citations

Whole-food sources of vitamin A more effectively inhibit female rat sexual maturation, mammary gland development, and mammary carcinogenesis than retinyl palmitate

McDaniel, S. M., O'Neill, C., Metz, R. P., Tarbutton, E., Stacewicz-Sapuntzakis, M., Heimendinger, J., Wolfe, P., Thompson, H. & Schedin, P., Jun 2007, In : Journal of Nutrition. 137, 6, p. 1415-1422 8 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Zebrafish Melanophilin Facilitates Melanosome Dispersion by Regulating Dynein

Sheets, L., Ransom, D. G., Mellgren, E. M., Johnson, S. L. & Schnapp, B. J., Oct 23 2007, In : Current Biology. 17, 20, p. 1721-1734 14 p.

Research output: Contribution to journalArticle

45 Scopus citations
2008

A pilot surrogate endpoint biomarker study of celecoxib in oral premalignant lesions

Wirth, L. J., Krane, J. F., Li, Y., Othus, M., Moran, A. E., Dorfman, D. M., Norris, C. M., Goguen, L., Posner, M. R., Haddad, R. I. & Bertagnolli, M. M., Oct 2008, In : Cancer Prevention Research. 1, 5, p. 339-348 10 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

A role for the podosome/invadopodia scaffold protein Tks5 in tumor growth in vivo

Blouw, B., Seals, D. F., Pass, I., Diaz, B. & Courtneidge, S. A., Sep 4 2008, In : European Journal of Cell Biology. 87, 8-9, p. 555-567 13 p.

Research output: Contribution to journalArticle

78 Scopus citations

Fas ligand-induced proinflammatory transcriptional responses in reconstructed human epidermis: Recruitment of the epidermal growth factor receptor and activation of MAP kinases

Farley, S. M., Purdy, D. E., Ryabinina, O. P., Schneider, P., Magun, B. E. & Iordanov, M. S., Jan 11 2008, In : Journal of Biological Chemistry. 283, 2, p. 919-928 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

FGF-dependent mechanosensory organ patterning in zebrafish

Nechiporuk, A. & Raible, D. W., Jun 27 2008, In : Science. 320, 5884, p. 1774-1777 4 p.

Research output: Contribution to journalArticle

130 Scopus citations

Hepatic macrophage iron aggravates experimental alcoholic steatohepatitis

Xiong, S., She, H., Zhang, A. S., Wang, J., Mkrtchyan, H., Dynnyk, A., Gordeuk, V. R., French, S. W., Enns, C. A. & Tsukamoto, H., Sep 2008, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 295, 3, p. G512-G521

Research output: Contribution to journalArticle

32 Scopus citations

Loss of singleminded-2s in the mouse mammary gland induces an epithelial-mesenchymal transition associated with up-regulation of slug and matrix metalloprotease 2

Laffin, B., Wellberg, E., Kwak, H. I., Burghardt, R. C., Metz, R. P., Gustafson, T., Schedin, P. & Porter, W. W., Mar 2008, In : Molecular and cellular biology. 28, 6, p. 1936-1946 11 p.

Research output: Contribution to journalArticle

67 Scopus citations

Neogenin-mediated hemojuvelin shedding occurs after hemojuvelin traffics to the plasma membrane

Zhang, A. S., Yang, F., Meyer, K., Hernandez, C., Chapman-Arvedson, T., Bjorkman, P. J. & Enns, C. A., Jun 20 2008, In : Journal of Biological Chemistry. 283, 25, p. 17494-17502 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Osteogenic differentiation of mesenchymal stem cells in defined protein beads

Lund, A. W., Bush, J. A., Plopper, G. E. & Stegemann, J. P., Oct 2008, In : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 87, 1, p. 213-221 9 p.

Research output: Contribution to journalArticle

40 Scopus citations
10 Scopus citations

The hereditary hemochromatosis protein, HFE, inhibits iron uptake via down-regulation of Zip14 in HepG2 Cells

Gao, J., Zhao, N., Knutson, M. D. & Enns, C. A., Aug 1 2008, In : Journal of Biological Chemistry. 283, 31, p. 21462-21468 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin

Kenny, H. A., Kaur, S., Coussens, L. M. & Lengyel, E., Apr 1 2008, In : Journal of Clinical Investigation. 118, 4, p. 1367-1379 13 p.

Research output: Contribution to journalArticle

236 Scopus citations

The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1

Gianni, D., Bohl, B., Courtneidge, S. A. & Bokoch, G. M., Jul 2008, In : Molecular biology of the cell. 19, 7, p. 2984-2994 11 p.

Research output: Contribution to journalArticle

99 Scopus citations

The mechanisms of spindle pole formation for the proper chromosome segregation

Ohsugi, M. & Oshimori, N., 2008, In : Seikagaku. 80, 3, p. 210-214 5 p.

Research output: Contribution to journalArticle

Use of Nramp2-transfected Chinese hamster ovary cells and reticulocytes from mk/mk mice to study iron transport mechanisms

Zhang, A. S., Canonne-Hergaux, F., Gruenheid, S., Gros, P. & Ponka, P., Oct 2008, In : Experimental hematology. 36, 10, p. 1227-1235 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Vesicular glutamate transporter 3 is required for synaptic transmission in zebrafish hair cells

Obholzer, N., Wolfson, S., Trapani, J. G., Mo, W., Nechiporuk, A., Busch-Nentwich, E., Seiler, C., Sidi, S., Söllner, C., Duncan, R. N., Boehland, A. & Nicolson, T., Feb 27 2008, In : Journal of Neuroscience. 28, 9, p. 2110-2118 9 p.

Research output: Contribution to journalArticle

181 Scopus citations

Zebrafish dorsal root ganglia neural precursor cells adopt a glial fate in the absence of neurogenin1

McGraw, H. F., Nechiporuk, A. & Raible, D. W., Nov 19 2008, In : Journal of Neuroscience. 28, 47, p. 12558-12569 12 p.

Research output: Contribution to journalArticle

51 Scopus citations
2009

An in-solution ultrasonication-assisted digestion method for improved extracellular matrix proteome coverage

Hansen, K. C., Kiemele, L., Maller, O., O'Brien, J., Shankar, A., Fornetti, J. & Schedin, P., 2009, In : Molecular and Cellular Proteomics. 8, 7, p. 1648-1657 10 p.

Research output: Contribution to journalArticle

68 Scopus citations

B7-H4-deficient mice display augmented neutrophil-mediated innate immunity

Zhu, G., Augustine, M. M., Azuma, T., Luo, L., Yao, S., Anand, S., Rietz, A. C., Huang, J., Xu, H., Flies, A. S., Flies, S. J., Tamada, K., Colonna, M., Van Deursen, J. M. A. & Chen, L., Feb 19 2009, In : Blood. 113, 8, p. 1759-1767 9 p.

Research output: Contribution to journalArticle

63 Scopus citations

CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages

DeNardo, D. G., Barreto, J. B., Andreu, P., Vasquez, L., Tawfik, D., Kolhatkar, N. & Coussens, L. M., Aug 4 2009, In : Cancer Cell. 16, 2, p. 91-102 12 p.

Research output: Contribution to journalArticle

775 Scopus citations

Cep72 regulates the localization of key centrosomal proteins and proper bipolar spindle formation

Oshimori, N., Li, X., Ohsugi, M. & Yamamoto, T., Jul 22 2009, In : EMBO Journal. 28, 14, p. 2066-2076 11 p.

Research output: Contribution to journalArticle

47 Scopus citations