Cell, Developmental, &amp; Cancer Biology

9/15/14 → 8/31/16

Project: Research project

Estrogen Receptors

Breast Neoplasms

src-Family Kinases

Neoplasms

Phosphotransferases

Macrophage-dependent regulation of neurotoxic APP fragments in a model system

2/15/14 → 1/31/16

Project: Research project

Contactins

Amyloid beta-Protein Precursor

Macrophages

Manduca

Insects

NSAIDs During Postpartum Involution for Breast Cancer Chemoprevention

Schedin, P. & Borges, V. F.

4/1/13 → 3/31/18

Project: Research project

Chemoprevention

Non-Steroidal Anti-Inflammatory Agents

Postpartum Period

Breast Neoplasms

Pregnancy

A Narrowed Window for Targeting Metabolic Flexibility in Breast Cancer Prevention

MacLean, P. S. & Schedin, P.

2/1/13 → 1/31/18

Project: Research project

Breast Neoplasms

Obesity

Menopause

Progesterone Receptors

Weight Gain

Common Mechanisms of Stem Cell Regulation in Bladder Cancer and Regeneration

Shin, K.

9/1/12 → 6/30/17

Project: Research project

Urinary Bladder Neoplasms

Regeneration

Stem Cells

Urinary Bladder

Cell Physiological Phenomena

Genetic analyses of axon transport and microtubule dynamics in Zebrafish

Nechiporuk, A.

7/25/12 → 6/30/17

Project: Research project

Zebrafish

Microtubules

Axons

Vertebrates

Nervous System

Vevo 2100 Ultrasound System

6/1/12 → 5/31/13

Project: Research project

Research Personnel

Mesothelioma

Neoplasms

Ultrasonography

Research

MicroRNA regulation of cell survival in angiogenesis and vessel maturation

Anand, S.

6/1/12 → 4/30/17

Project: Research project

MicroRNAs

Cell Survival

p120 GTPase Activating Protein

Blood Vessels

Pathologic Neovascularization

A novel role for receptor tyrosine phosphatase in neuroblast migration

5/1/12 → 4/30/15

Project: Research project

Ephrins

Phosphoric Monoester Hydrolases

Tight Junctions

Eph Family Receptors

Manduca

Leukocyte Biomarkers for Predicting Human Breast Cancer Outcomes

Coussens, L., Krummel, M., van 't Veer, L. J. & Daldrup-Link, H. E.

9/23/11 → 10/31/16

Project: Research project

Leukocytes

Biomarkers

Breast Neoplasms

Neoplasms

Therapeutics

Regulating the Immune Microenvironment in Breast Cancer

5/1/11 → 3/31/16

Project: Research project

Breast Neoplasms

Neoplasms

Interleukin-4

Breast

Epidermal Growth Factor

Kinases as therapeutic targets for cancer progression

1/1/11 → 12/31/16

Project: Research project

Phosphotransferases

Neoplasms

Therapeutics

Growth

Podosomes

Identification of target genes for Lhx3 in gonadotropes

1/1/11 → 12/31/13

Project: Research project

High-Throughput Nucleotide Sequencing

Follicle Stimulating Hormone

Genes

Gene Regulatory Networks

Luteinizing Hormone

Generation and utility of NADPH oxidase inhibitors

7/6/10 → 6/30/13

Project: Research project

NADPH Oxidase

Neoplasms

Research

Preclinical Drug Evaluations

Human Genome

Novel mechanisms of Ephrin-A reverse signaling in neuronal migration

7/1/10 → 6/30/13

Project: Research project

Ephrins

Eph Family Receptors

Enteric Nervous System

Nervous System

Neurons

Improved Drug Delivery to Tumors Using Novel Tissue Perfusion Approaches

Coussens, L., Boudreau, N. J. & Daldrup-Link, H. E.

7/15/09 → 5/31/14

Project: Research project

Perfusion

Pharmaceutical Preparations

Capillary Permeability

Neoplasms

Breast Neoplasms

Regulation of Inflammation-Associated Epithelial Cancer Development

7/1/08 → 5/31/14

Project: Research project

Inflammation

B-Lymphocytes

Neoplasms

B-Lymphocyte Subsets

Leukocytes

Functional investigation of hemojuvelin in regulation of hepcidin expression

Zhang, A.

6/1/08 → 5/31/13

Project: Research project

Hepcidins

Iron

Iron Overload

Hemochromatosis

Homeostasis

Inflammation and Lung Carcinogenesis

Jablons, D. M. & Coussens, L.

5/1/08 → 3/31/14

Project: Research project

Pneumonia

Carcinogenesis

Hedgehogs

Lung

Stem Cell Niche

High Throughput Microscopy Assays to Identify Inhibitors of Metastasis

12/10/07 → 2/28/11

Project: Research project

Microscopy

Neoplasm Metastasis

Peptide Hydrolases

Neoplasms

Extracellular Matrix

Reactive Oxygen Species and Cancer Cell Invasion

7/1/07 → 5/31/12

Project: Research project

Reactive Oxygen Species

Neoplasms

Basement Membrane

Peptide Hydrolases

Podosomes

Development of Epibranchial Placodes and Ganglia in Zebrafish

Nechiporuk, A.

5/1/07 → 2/28/13

Project: Research project

Zebrafish

Ganglia

Vertebrates

Parasympathetic Ganglia

Developmental Biology

Role of APP-related Proteins During Neuronal Migration

9/1/05 → 8/31/12

Project: Research project

Amyloid beta-Protein Precursor

Proteins

Nervous System

Alzheimer Disease

Amyloid Precursor Protein Secretases

Regulation and function of transferrin receptor 2

Enns, C.

7/1/05 → 3/31/18

Project: Research project

Transferrin Receptors

Iron

Hemochromatosis

Homeostasis

Iron Overload

Conference on Molecular Targets for Cancer Therapy

2/1/05 → 1/31/06

Project: Research project

Neoplasms

Therapeutics

Posters

Gastrointestinal Stromal Tumors

Neoplastic Stem Cells

Center on Proteolytic Pathways (RMI)

Coussens, L., Smith, J., Sloane, B., Mustelin, T., Osterman, A., Salvesen, G., Strongin, A., Bogyo, M. & Godzik, A.

9/30/04 → 7/31/10

Project: Research project

Blood Vessels

Technology

Peptide Hydrolases

Proteolysis

Modems

FGF SIGNALING DURING CRANIAL PLACODE DEVELOPMENT

Nechiporuk, A.

5/1/04 → 4/30/07

Project: Research project

Fibroblast Growth Factors

Fibroblast Growth Factor Receptors

Zebrafish

Sensory Ganglia

Cranial Nerves

LIM Homeodomain Factors and Pituitary Gene Expression

3/1/04 → 2/28/10

Project: Research project

Gene Expression

Phosphorylation

Gonadotropin-Releasing Hormone

Genes

Alpha Subunit Glycoprotein Hormones

Biological and genetic analysis of Fish, a Src substrate

2/19/04 → 1/31/10

Project: Research project

Fishes

src Homology Domains

Intercellular Signaling Peptides and Proteins

Neoplasms

Proteins

Microenvironmental Regulation of Tumor Progression

7/1/03 → 4/30/09

Project: Research project

Collagen Type I

Matrix Metalloproteinases

Neoplasms

Transgenic Mice

Matrix Metalloproteinase Inhibitors

Nipkow-disk Confocal Microscope for Live-Cell Imaging

5/1/03 → 4/30/05

Project: Research project

Islets of Langerhans

Research

Lasers

RNA Transport

Research Personnel

Copper entry into human cells

David, L., Ralle, M., Blackburn, N., Enns, C., Bjorkman, P., Hubbard, A., Kaplan, J., Unger, V., Lutsenko, S. & Enns, C.

12/1/02 → 8/31/15

Project: Research project

Metal ions

Copper

Transferrin Receptors

Homeostasis

Proteins

Regulation of Epithelial Cancer by MMP-9/gelatinase B

4/1/02 → 9/30/07

Project: Research project

Matrix Metalloproteinase 9

Matrix Metalloproteinases

Neoplasms

Carcinogenesis

Matrix Metalloproteinase Inhibitors

Endocrine Status of MG Stroma Alters Breast CA Invasion

Schedin, P.

6/4/01 → 5/31/06

Project: Research project

Breast

Epithelial-Mesenchymal Transition

Pregnancy

Breast Neoplasms

Neoplasms

REGULATION OF KINESIN MOTORS

4/1/00 → 3/31/06

Project: Research project

Kinesin

Proteins

Light

Microtubules

Motor Activity

IRON TRANSPORT IN MAMMALIAN CELLS

Enns, C., Schlisky, M., Friedman, J., Wessling-Resnick, M. & Aisen, P.

5/1/99 → 4/30/06

Project: Research project

Transferrin Receptors

Iron

Hemochromatosis

Genes

Protein Interaction Maps

CYTOPLASMIC MRNA TRANSPORT IN XENOPUS OOCYTES

1/1/98 → 12/31/02

Project: Research project

Xenopus

Oocytes

Proteins

Organized Financing

3' Untranslated Regions

OREGON CANCER CENTER

Mori, M. (., Corless, C., Beer, T. (., McWeeney, S., Harrington, C. (., Bagby, G., Druker, B., Sexton, G., Hall, A., Henner, W., Samuels, M. H., Bakke, A., Hoatlin, M., Baetscher, M., Keller, T., Nagalla, S., Magun, B. E., Koop, D. R., Mauro, M. J., Blanke, C. D., Bakke, A., Baetscher, M., Koop, D., Spellman, P., David, L., Coussens, L., Streeter, P., Thomas, G., Mori, M. (., Mori, M. (., Harrington, C. (., Bergan, R. & Blanke, C.

8/1/97 → 6/30/17

Project: Research project

Neoplasms

Research

Research Personnel

Biostatistics

Translational Medical Research

GUIDANCE OF NEURONAL MIGRATION IN EMBRYONIC DEVELOPMENT

12/12/96 → 4/30/07

Project: Research project

Embryonic Development

Cues

Cell Movement

Enteric Nervous System

Protein-Tyrosine Kinases

ECM MEDIATORS OF CHEMOPREVENTIVE AGENTS IN THE BREAST

Schedin, P.

6/1/96 → 5/31/01

Project: Research project

Extracellular Matrix

Breast

Epithelial Cells

Carcinogenesis

Cell Death

NEUROENDOCRINE REGULATION OF CREB BY CAMP AND CALCIUM

8/10/95 → 7/31/99

Project: Research project

Calcium-Calmodulin-Dependent Protein Kinases

Calcium-Calmodulin-Dependent Protein Kinase Type 2

Calcium

Phosphorylation

Calcium-Calmodulin-Dependent Protein Kinase Type 4

DEVELOPMENTAL ROLE OF G PROTEINS IN NEURONAL MIGRATION

8/1/94 → 7/31/95

Project: Research project

GTP-Binding Proteins

Gi-Go GTP-Binding Protein alpha Subunits

Neurons

Enteric Nervous System

Nervous System

DEVELOPMENTAL ROLE OF G PROTEINS IN NEURONAL MIGRATION

8/1/94 → 6/30/04

Project: Research project

GTP-Binding Proteins

Neurons

Calcium

Calcium Channels

Enteric Nervous System

GORDON RESEARCH CONFERENCE ON HORMONE ACTION

8/1/93 → 7/31/94

Project: Research project

Hormones

Research

Posters

Steroid Receptors

Cell Membrane

ROLE OF THE PROTEASE STROMELYSIN IN AXON INVASIVENESS

Ciment, G.

7/1/92 → 6/30/95

Project: Research project

Matrix Metalloproteinase 3

Axons

Peptide Hydrolases

Neurites

PC12 Cells

MOLECULAR BASIS OF AXONAL TRANSPORT

8/1/89 → 12/31/97

Project: Research project

Transport Vesicles

kinesin

Microtubules

Organelles

Kinesin

STRUCTURE - FUNCTION OF THE HUMAN TRANSFERRIN RECEPTOR

Enns, C.

7/1/89 → 6/30/04

Project: Research project

Transferrin Receptors

Proteins

Iron

Endocytosis

Transferrin

REGULATION OF PROLACTIN GENE EXPRESSION

9/20/88 → 11/30/06

Project: Research project

Gene Expression Regulation

Prolactin

Chromatin

Co-Repressor Proteins

Genes

CHARACTERIZATION OF A NEURAL CREST-DERIVED CDNA LIBRARY

Ciment, G.