Organization profile

Organization profile

To advance the understanding of problems relevant to human health and disease.

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Transferrin Receptors Medicine & Life Sciences
Iron Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Hepcidins Medicine & Life Sciences
Proteins Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Transferrin Medicine & Life Sciences
Manduca Medicine & Life Sciences

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Projects 1978 2020

Iron
Hepcidins
Hemochromatosis
Homeostasis
Hepatocytes

Administration (Admin Core)

Courtneidge, S., Powis, G., Wechsler-Reya, R., Ranscht, B., Mercola, M., Stallcup, W. B., Osterman, A., Moscat, J., Rickert, R., Hauser, C., Chanda, S., Wolf, D. & Liddington, R.

National Institutes of Health

5/1/974/30/20

Project: Research project

Tumor Microenvironment
Neoplasm Metastasis
Organized Financing
Neoplasms
Publications

Research Output 1969 2019

5 Citations (Scopus)

Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models

Keklikoglou, I., Cianciaruso, C., Güç, E., Squadrito, M. L., Spring, L. M., Tazzyman, S., Lambein, L., Poissonnier, A., Ferraro, G. B., Baer, C., Cassará, A., Guichard, A., Iruela-Arispe, M. L., Lewis, C. E., Coussens, L., Bardia, A., Jain, R. K., Pollard, J. W. & De Palma, M., Feb 1 2019, In : Nature Cell Biology. 21, 2, p. 190-202 13 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Drug Therapy
Neoplasms
Annexin A6
Exosomes
1 Citation (Scopus)

Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets

Cassetta, L., Fragkogianni, S., Sims, A. H., Swierczak, A., Forrester, L. M., Zhang, H., Soong, D. Y. H., Cotechini, T., Anur, P., Lin, E., Fidanza, A., Lopez-Yrigoyen, M., Millar, M. R., Urman, A., Ai, Z., Spellman, P., Hwang, E. S., Dixon, J. M., Wiechmann, L., Coussens, L. M. & 2 othersSmith, H. O. & Pollard, J. W., Apr 15 2019, In : Cancer Cell. 35, 4, p. 588-602.e10

Research output: Contribution to journalArticle

Open Access
Monocytes
Biomarkers
Macrophages
Breast Neoplasms
Transcriptome

Late-stage tumor regression after PD-L1 blockade plus a concurrent OX40 agonist

Polesso, F., Weinberg, A. D. & Moran, A., Feb 1 2019, In : Cancer Immunology Research. 7, 2, p. 269-281 13 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Neoplasms
Neoplasm Antigens
CD8 Antigens
Granzymes