Research Output 1978 2019

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2012
15 Citations (Scopus)

Genetic Differences in Transcript Responses to Low-Dose Ionizing Radiation Identify Tissue Functions Associated with Breast Cancer Susceptibility

Snijders, A. M., Marchetti, F., Bhatnagar, S., Duru, N., Han, J., Hu, Z., Mao, J. H., Gray, J. & Wyrobek, A. J., Oct 15 2012, In : PLoS One. 7, 10, e45394.

Research output: Contribution to journalArticle

Ionizing radiation
Ionizing Radiation
ionizing radiation
breast neoplasms
Dosimetry
12 Citations (Scopus)

Genomic aberrations in normal tissue adjacent to HER2-amplified breast cancers: Field cancerization or contaminating tumor cells?

Sadanandam, A., Lal, A., Benz, S. C., Eppenberger-Castori, S., Scott, G., Gray, J., Spellman, P., Waldman, F. & Benz, C. C., Dec 2012, In : Breast Cancer Research and Treatment. 136, 3, p. 693-703 11 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Neoplasms
Breast
Segmental Mastectomy
erbB-2 Genes
31 Citations (Scopus)

Genomics: The breast cancer landscape

Gray, J. & Druker, B., Jun 21 2012, In : Nature. 486, 7403, p. 328-329 2 p.

Research output: Contribution to journalArticle

Neoplastic Gene Expression Regulation
Neoplastic Cell Transformation
DNA Copy Number Variations
Genetic Translocation
Aromatase Inhibitors
31 Citations (Scopus)

Goniometric measurements of thick tissue using Monte Carlo simulations to obtain the single scattering anisotropy coefficient

Hall, G., Jacques, S., Eliceiri, K. W. & Campagnola, P. J., Nov 1 2012, In : Biomedical Optics Express. 3, 11, p. 2707-2719 13 p.

Research output: Contribution to journalArticle

Anisotropy
anisotropy
coefficients
scattering
simulation
25 Citations (Scopus)

Hyaluronan anchored to activated CD44 on central nervous system vascular endothelial cells promotes lymphocyte extravasation in experimental autoimmune encephalomyelitis

Winkler, C. W., Foster, S. C., Matsumoto, S., Preston, M. A., Xing, R., Bebo, B. F., Banine, F., Berny-Lang, M. A., Itakura, A., McCarty, O. & Sherman, L. L., Sep 28 2012, In : Journal of Biological Chemistry. 287, 40, p. 33237-33251 15 p.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Lymphocytes
Endothelial cells
Neurology
Hyaluronic Acid
57 Citations (Scopus)

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target

McElwee, J. L., Mohanan, S., Griffith, O. L., Breuer, H. C., Anguish, L. J., Cherrington, B. D., Palmer, A. M., Howe, L. R., Subramanian, V., Causey, C. P., Thompson, P. R., Gray, J. & Coonrod, S. A., Oct 30 2012, In : BMC Cancer. 12, 500.

Research output: Contribution to journalArticle

Tumor Biomarkers
Breast Neoplasms
Cell Line
cdc Genes
Neoplasms
5 Citations (Scopus)

Improved deposition and deprotection of silane tethered 3,4 hydroxypyridinone (HOPO) ligands on functionalized nanoporous silica

Davidson, J. D., Wiacek, R. J., Burton, S., Li, X. S., Fryxell, G. E., Addleman, R. S., Yantasee, W., Sangvanich, T. & Pattamakomsan, K., Apr 2012, In : Inorganic Chemistry Communications. 18, p. 92-96 5 p.

Research output: Contribution to journalArticle

Silanes
silanes
Silicon Dioxide
Monolayers
Blood
5 Citations (Scopus)

Influence of acute hyperglycemia on otoacoustic emissions and the medial olivocochlear reflex

Jacobs, P., Konrad-Martin, D., McMillan, G. P., McDermott, D., Fausti, S. A., Kagen, D. & Wan, E. A., Feb 2012, In : Journal of the Acoustical Society of America. 131, 2, p. 1296-1306 11 p.

Research output: Contribution to journalArticle

hyperglycemia
reflexes
glucose
stimuli
sugars
46 Citations (Scopus)

Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis

Tucker, E., Verbout, N. G., Leung, P. Y., Hurst, S., McCarty, O., Gailani, D. & Gruber, A., May 17 2012, In : Blood. 119, 20, p. 4762-4768 7 p.

Research output: Contribution to journalArticle

Factor XI
Sepsis
Chemical activation
Inflammation
Coagulation
28 Citations (Scopus)

Inhibition of Factor XII-Mediated Activation of Factor XI Provides Protection Against Experimental Acute Ischemic Stroke in Mice

Leung, P. Y., Hurst, S., Berny-Lang, M. A., Verbout, N. G., Gailani, D., Tucker, E., Wang, R. K., McCarty, O. & Gruber, A., Sep 2012, In : Translational Stroke Research. 3, 3, p. 381-389 9 p.

Research output: Contribution to journalArticle

Factor XI
Factor XII
Stroke
Hemostasis
Antibodies
13 Citations (Scopus)

Integrating biological knowledge into variable selection: an empirical Bayes approach with an application in cancer biology

Hill, S. M., Neve, R. M., Bayani, N., Kuo, W. L., Ziyad, S., Spellman, P., Gray, J. & Mukherjee, S., May 11 2012, In : BMC Bioinformatics. 13, 1, 94.

Research output: Contribution to journalArticle

Empirical Bayes
Variable Selection
Biology
Cancer
Specifications
13 Citations (Scopus)
Optical tomography
blood flow
strain rate
Strain rate
Blood
33 Citations (Scopus)

In vivo outer hair cell length changes expose the active process in the cochlea

Zha, D., Chen, F., Ramamoorthy, S., Fridberger, A., Choudhury, N., Jacques, S., Wang, R. K. & Nuttall, A., Apr 9 2012, In : PLoS One. 7, 4, e32757.

Research output: Contribution to journalArticle

Outer Auditory Hair Cells
Cochlea
hairs
Amplification
Cells
38 Citations (Scopus)

Lectin chromatography/mass spectrometry discovery workflow identifies putative biomarkers of aggressive breast cancers

Drake, P. M., Schilling, B., Niles, R. K., Prakobphol, A., Li, B., Jung, K., Cho, W., Braten, M., Inerowicz, H. D., Williams, K., Albertolle, M., Held, J. M., Iacovides, D., Sorensen, D. J., Griffith, O. L., Johansen, E., Zawadzka, A. M., Cusack, M. P., Allen, S., Gormley, M. & 6 others, Hall, S. C., Witkowska, H. E., Gray, J., Regnier, F., Gibson, B. W. & Fisher, S. J., Apr 6 2012, In : Journal of Proteome Research. 11, 4, p. 2508-2520 13 p.

Research output: Contribution to journalArticle

Workflow
Biomarkers
Chromatography
Lectins
Mass spectrometry
23 Citations (Scopus)

Loss of cell-surface laminin anchoring promotes tumor growth and is associated with poor clinical outcomes

Akhavan, A., Griffith, O. L., Soroceanu, L., Leonoudakis, D., Luciani-Torres, M. G., Daemen, A., Gray, J. & Muschler, J., May 15 2012, In : Cancer Research. 72, 10, p. 2578-2588 11 p.

Research output: Contribution to journalArticle

Laminin
Growth
Neoplasms
Brain Neoplasms
Disease Progression
75 Citations (Scopus)

Measurement of Single Cell Refractive Index, Dry Mass, Volume, and Density Using a Transillumination Microscope

Phillips, K. G., Jacques, S. & McCarty, O., Sep 13 2012, In : Physical Review Letters. 109, 11, 118105.

Research output: Contribution to journalArticle

microscopes
refractivity
optical microscopes
cells
dimensional measurement
80 Citations (Scopus)

Mechanical property characterization of electrospun recombinant human tropoelastin for vascular graft biomaterials

McKenna, K., Hinds, M., Sarao, R. C., Wu, P. C., Maslen, C., Glanville, R. W., Babcock, D. & Gregory, K., Jan 2012, In : Acta Biomaterialia. 8, 1, p. 225-233 9 p.

Research output: Contribution to journalArticle

Tropoelastin
Biocompatible Materials
Biomaterials
Grafts
Blood Vessels
12 Citations (Scopus)

Modeling and simulation of procoagulant circulating tumor cells in flow

Lee, A. M., Tormoen, G. W., Kanso, E., McCarty, O. & Newton, P. K., 2012, In : Frontiers in Oncology. 2 SEP, Article 108.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Thrombin
Blood Coagulation Factors
Enzymes
Thrombophilia
29 Citations (Scopus)

Omics and therapy - A basis for precision medicine

Garay, J. P. & Gray, J., Apr 2012, In : Molecular Oncology. 6, 2, p. 128-139 12 p.

Research output: Contribution to journalArticle

Precision Medicine
Genome
Neoplasms
Disease Management
Therapeutics
19 Citations (Scopus)

Optical detection of indocyanine green encapsulated biocompatible poly (lactic-co-glycolic) acid nanoparticles with photothermal optical coherence tomography

Subhash, H. M., Xie, H., Smith, J. W. & McCarty, O., Mar 1 2012, In : Optics Letters. 37, 5, p. 981-983 3 p.

Research output: Contribution to journalArticle

tomography
nanoparticles
acids
interferometry
sensitivity
53 Citations (Scopus)

Optical quantification of cellular mass, volume, and density of circulating tumor cells identified in an ovarian cancer patient

Phillips, K. G., Velasco, C. R., Li, J., Kolatkar, A., Luttgen, M., Bethel, K., Duggan, B., Kuhn, P. & McCarty, O., 2012, In : Frontiers in Oncology. 2 JUL, Article 72.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Ovarian Neoplasms
Leukocytes
Interference Microscopy
Neoplasms
4 Citations (Scopus)

Optimization-based inference for temporally evolving networks with applications in biology

Chang, Y. H., Gray, J. & Tomlin, C., Dec 1 2012, In : Journal of Computational Biology. 19, 12, p. 1307-1323 17 p.

Research output: Contribution to journalArticle

Genetic Network
Biological Networks
Biology
Research Design
Costs and Cost Analysis
47 Citations (Scopus)

Parametric imaging of the local attenuation coefficient in human axillary lymph nodes assessed using optical coherence tomography

Scolaro, L., McLaughlin, R. A., Klyen, B. R., Wood, B. A., Robbins, P. D., Saunders, C. M., Jacques, S. & Sampson, D. D., Feb 1 2012, In : Biomedical Optics Express. 3, 2, p. 366-379 14 p.

Research output: Contribution to journalArticle

lymphatic system
Optical Coherence Tomography
attenuation coefficients
tomography
Lymph Nodes
236 Citations (Scopus)

Pathologic complete response predicts recurrence-free survival more effectively by cancer subset: Results from the I-SPY 1 TRIAL - CALGB 150007/150012, ACRIN 6657

Esserman, L. J., Berry, D. A., DeMichele, A., Carey, L., Davis, S. E., Buxton, M., Hudis, C., Gray, J., Perou, C., Yau, C., Livasy, C., Krontiras, H., Montgomery, L., Tripathy, D., Lehman, C., Liu, M. C., Olopade, O. I., Rugo, H. S., Carpenter, J. T., Dressler, L. & 8 others, Chhieng, D., Singh, B., Mies, C., Rabban, J., Chen, Y. Y., Giri, D., Van't Veer, L. & Hylton, N., Sep 10 2012, In : Journal of Clinical Oncology. 30, 26, p. 3242-3249 8 p.

Research output: Contribution to journalArticle

Recurrence
Survival
Hormones
Neoplasms
Breast Neoplasms
9 Citations (Scopus)

Plasma kallikrein: Novel functions for an old protease

Renné, T. & Gruber, A., Jun 2012, In : Thrombosis and Haemostasis. 107, 6, p. 1012-1013 2 p.

Research output: Contribution to journalArticle

Prekallikrein
Plasma Kallikrein
Hemostasis
Thrombosis
Peptide Hydrolases
23 Citations (Scopus)

Quantification of cellular volume and sub-cellular density fluctuations: Comparison of normal peripheral blood cells and circulating tumor cells identified in a breast cancer patient

Phillips, K. G., Kolatkar, A., Rees, K. J., Rigg, R., Marrinucci, D., Luttgen, M., Bethel, K., Kuhn, P. & McCarty, O., 2012, In : Frontiers in Oncology. 2 AUG, Article 96.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Blood Cells
Breast Neoplasms
Neoplasm Metastasis
Leukocytes
15 Citations (Scopus)

Reflectance confocal microscopy of optical phantoms

Jacques, S., Wang, B. & Samatham, R., Jun 1 2012, In : Biomedical Optics Express. 3, 6, p. 1162-1172 11 p.

Research output: Contribution to journalArticle

Polyurethanes
Polystyrenes
Anisotropy
Microspheres
Confocal Microscopy
11 Citations (Scopus)

Regulation of the mTOR-Rac1 axis in platelet function

Aslan, J. & McCarty, O., Jan 2012, In : Small GTPases. 3, 1

Research output: Contribution to journalArticle

Platelets
Blood Platelets
Platelet Membrane Glycoproteins
rho GTP-Binding Proteins
Pseudopodia
4 Citations (Scopus)
Venous Insufficiency
Sheep
Staining and Labeling
Venous Valves
Stents
39 Citations (Scopus)

Sensorimotor integration for multisegmental frontal plane balance control in humans

Goodworth, A. D. & Peterka, R. B., Jan 2012, In : Journal of Neurophysiology. 107, 1, p. 12-28 17 p.

Research output: Contribution to journalArticle

Sensory Feedback
Cues
Torque
Foot
5 Citations (Scopus)

Stochastic perturbationmethods for spike-timing-dependent plasticity

Leen, T. K. & Friel, R., 2012, In : Neural Computation. 24, 5, p. 1109-1146 38 p.

Research output: Contribution to journalArticle

Learning
Weights and Measures
Plasticity
Machine Learning
Equations
13 Citations (Scopus)

Structural and cellular characterization of electrospun recombinant human tropoelastin biomaterials

McKenna, K., Gregory, K., Sarao, R. C., Maslen, C., Glanville, R. W. & Hinds, M., Aug 2012, In : Journal of Biomaterials Applications. 27, 2, p. 219-230 12 p.

Research output: Contribution to journalArticle

Tropoelastin
Biocompatible Materials
Biomaterials
Grafts
Cell growth
252 Citations (Scopus)

Subtype and pathway specific responses to anticancer compounds in breast cancer

Heiser, L., Sadanandam, A., Kuo, W. L., Benz, S. C., Goldstein, T. C., Ng, S., Gibb, W. J., Wang, N. J., Ziyad, S., Tong, F., Bayani, N., Hu, Z., Billig, J. I., Dueregger, A., Lewis, S., Jakkula, L., Korkola, J., Durinck, S., Pepin, F., Guan, Y. & 23 others, Purdom, E., Neuvial, P., Bengtsson, H., Wood, K. W., Smith, P. G., Vassilev, L. T., Hennessy, B. T., Greshock, J., Bachman, K. E., Hardwicke, M. A., Park, J. W., Marton, L. J., Wolf, D. M., Collisson, E. A., Neve, R. M., Mills, G., Speed, T. P., Feiler, H., Richard, F. W., Haussler, D., Stuart, J. M., Gray, J. & Spellman, P., Feb 21 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 8, p. 2724-2729 6 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Cell Line
Pharmaceutical Preparations
Therapeutics
Neoplasms

SU‐E‐J‐196: In‐Vivo Tumor Blood‐Oxygen Content Measurement via Interstitial Optical Transmission Spectroscopy

Campos, D., Yan, Y., Zhao, D., Kissick, M., Jacques, S., Van Der Kogel, A. & Kimple, R., 2012, In : Medical Physics. 39, 6, p. 3698 1 p.

Research output: Contribution to journalArticle

Spectrum Analysis
Oxygen
Needles
Neoplasms
Oxyhemoglobins

SU‐E‐J‐197: A Novel Optical Interstitial Fiber Spectroscopic System for Real‐Time Tissue Micro‐Vascular Hemodynamics Monitoring

Zhao, D., Campos, D., Yan, Y., Kimple, R., Jacques, S., Van Der Kogel, A. & Kissick, M., 2012, In : Medical Physics. 39, 6, p. 3698 1 p.

Research output: Contribution to journalArticle

Optical Fibers
Hemodynamics
Light
Blood Volume
Heterografts
43 Citations (Scopus)

Suppression of arterial thrombosis without affecting hemostatic parameters with a cell-penetrating PAR1 pepducin

Zhang, P., Gruber, A., Kasuda, S., Kimmelstiel, C., O'Callaghan, K., Cox, D. H., Bohm, A., Baleja, J. D., Covic, L. & Kuliopulos, A., Jul 3 2012, In : Circulation. 126, 1, p. 83-91 9 p.

Research output: Contribution to journalArticle

Hemostatics
Percutaneous Coronary Intervention
Thrombosis
Acute Coronary Syndrome
Blood Platelets
35 Citations (Scopus)

The transcription factor ZNF217 Is a prognostic biomarker and therapeutic target during breast cancer progression

Littlepage, L. E., Adler, A. S., Kouros-Mehr, H., Huang, G., Chou, J., Krig, S. R., Griffi th, O. L., Korkola, J., Qu, K., Lawson, D. A., Xue, Q., Sternlicht, M. D., Dijkgraaf, G. J. P., Yaswen, P., Rugo, H. S., Sweeney, C. A., Collins, C. C., Gray, J., Chang, H. Y. & Werb, Z., Jul 2012, In : Cancer Discovery. 2, 7, p. 638-651 14 p.

Research output: Contribution to journalArticle

triciribine
Transcription Factors
Biomarkers
Breast Neoplasms
Neoplasms
14 Citations (Scopus)

Tri-modal confocal mosaics detect residual invasive squamous cell carcinoma in Mohs surgical excisions

Gareau, D., Bar, A., Snaveley, N., Lee, K., Chen, N., Swanson, N., Simpson, E. & Jacques, S., Jun 2012, In : Journal of Biomedical Optics. 17, 6, 066018.

Research output: Contribution to journalArticle

cancer
Fluorescence
Acridine Orange
fluorescence
Eosine Yellowish-(YS)
32 Citations (Scopus)

What are we learning from the cancer genome?

Collisson, E. A., Cho, R. J. & Gray, J., Nov 2012, In : Nature Reviews Clinical Oncology. 9, 11, p. 621-630 10 p.

Research output: Contribution to journalArticle

Learning
Genome
Neoplasms
Technology
Precision Medicine
27 Citations (Scopus)

Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors

Petrillo, L. A., Wolf, D. M., Kapoun, A. M., Wang, N. J., Barczak, A., Xiao, Y., Korkaya, H., Baehner, F., Lewicki, J., Wicha, M., Park, J. W., Spellman, P., Gray, J., Van'T Veer, L. & Esserman, L. J., Oct 2012, In : Breast Cancer Research and Treatment. 135, 3, p. 913-922 10 p.

Research output: Contribution to journalArticle

Neoplasm Genes
Heterografts
Breast Neoplasms
Gene Expression
Neoplasms
2011
9 Citations (Scopus)
Prostheses and Implants
Sensory feedback
Feedback
Sensory Feedback
Feedback control
23 Citations (Scopus)

Activated factor XI inhibits chemotaxis of polymorphonuclear leukocytes

Itakura, A., Verbout, N. G., Phillips, K. G., Insall, R. H., Gailani, D., Tucker, E., Gruber, A. & McCarty, O., Nov 2011, In : Journal of Leukocyte Biology. 90, 5, p. 923-927 5 p.

Research output: Contribution to journalArticle

Factor XIa
Chemotaxis
Neutrophils
Leukocytes
Innate Immunity
118 Citations (Scopus)

A differentially amplified motion in the ear for near-threshold sound detection

Chen, F., Zha, D., Fridberger, A., Zheng, J., Choudhury, N., Jacques, S., Wang, R. K., Shi, X. & Nuttall, A., Jun 2011, In : Nature Neuroscience. 14, 6, p. 770-774 5 p.

Research output: Contribution to journalArticle

Basilar Membrane
Ear
Vibration
Pressure
Noise
43 Citations (Scopus)

A framework for rapid visual image search using single-trial brain evoked responses

Huang, Y., Erdogmus, D., Pavel, M., Mathan, S. & Hild, K. E., Jun 2011, In : Neurocomputing. 74, 12-13, p. 2041-2051 11 p.

Research output: Contribution to journalArticle

Evoked Potentials
Support vector machines
Brain
Logistics
Classifiers
13 Citations (Scopus)

A new treasure in the breast cancer gene hunt

Spellman, P. & Gray, J., Apr 2011, In : Nature Medicine. 17, 4, p. 422-423 2 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Carrier Proteins
Genes
Gene Amplification
28 Citations (Scopus)

Assessment of strain and strain rate in embryonic chick heart in vivo using tissue Doppler optical coherence tomography

Li, P., Liu, A., Shi, L., Yin, X., Rugonyi, S. & Wang, R. K., Nov 21 2011, In : Physics in Medicine and Biology. 56, 22, p. 7081-7092 12 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Biomechanical Phenomena
1 Citation (Scopus)

Breakup feared after filamin leaves GPIb

Berny-Lang, M. A. & McCarty, O., Mar 3 2011, In : Blood. 117, 9, p. 2564-2565 2 p.

Research output: Contribution to journalArticle

Filamins
Platelet Glycoprotein GPIb-IX Complex
Platelet Membrane Glycoproteins
Cytoskeletal Proteins
von Willebrand Factor
13 Citations (Scopus)

Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets

Aslan, J., Spencer, A. M., Loren, C. P., Pang, J., Welch, H. C., Greenberg, D. L. & McCarty, O., Sep 1 2011, In : Journal of Molecular Signaling. 6, 11.

Research output: Contribution to journalArticle

Guanine Nucleotide Exchange Factors
Platelets
Blood Platelets
rac1 GTP-Binding Protein
rho GTP-Binding Proteins
27 Citations (Scopus)

Contributions of skin and muscle afferent input to movement sense in the human hand

Cordo, P., Horn, J. L., Künster, D., Cherry, A., Bratt, A. & Gurfinkel, V., Apr 2011, In : Journal of Neurophysiology. 105, 4, p. 1879-1888 10 p.

Research output: Contribution to journalArticle

Hand
Muscles
Skin
Proprioception
Joints