Research Output 1978 2019

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2017
8 Citations (Scopus)

Far-Red and Near-Infrared Seminaphthofluorophores for Targeted Pancreatic Cancer Imaging

Wang, L., Barth, C. W., Sibrian-Vazquez, M., Escobedo, J. O., Lowry, M., Muschler, J., Li, H., Gibbs, S. & Strongin, R. M., Jan 31 2017, In : ACS Omega. 2, 1, p. 154-163 10 p.

Research output: Contribution to journalArticle

Infrared radiation
Fluorescent Dyes
Imaging techniques
Tissue
Molecular Probes
9 Citations (Scopus)

Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques /631/326/596/1550 /631/326/596/2555 /631/326/596/2557 article

Burwitz, B., Wettengel, J. M., Mück-Häusl, M. A., Ringelhan, M., Ko, C., Festag, M. M., Hammond, K. B., Northrup, M., Bimber, B. N., Jacob, T., Reed, J. S., Norris, R., Park, B., Moller-Tank, S., Esser, K., Greene, J. M., Wu, H. L., Abdulhaqq, S., Webb, G., Sutton, W. F. & 8 others, Klug, A., Swanson, T., Legasse, A. W., Vu, T. T., Asokan, A., Haigwood, N., Protzer, U. & Sacha, J., Dec 1 2017, In : Nature Communications. 8, 1, 2146.

Research output: Contribution to journalArticle

hepatitis
polypeptides
Macaca
viruses
infectious diseases
21 Citations (Scopus)

HER2 reactivation through acquisition of the HER2 L755S mutation as a mechanism of acquired resistance to HER2-targeted therapy in HER2+ breast cancer

Xu, X., De Angelis, C., Burke, K. A., Nardone, A., Hu, H., Qin, L., Veeraraghavan, J., Sethunath, V., Heiser, L., Wang, N., Ng, C. K. Y., Chen, E. S., Renwick, A., Wang, T., Nanda, S., Shea, M., Mitchell, T., Rajendran, M., Waters, I., Zabransky, D. J. & 14 others, Scott, K. L., Gutierrez, C., Nagi, C., Geyer, F. C., Chamness, G. C., Park, B. H., Shaw, C. A., Hilsenbeck, S. G., Rimawi, M. F., Gray, J., Weigelt, B., Reis-Filho, J. S., Osborne, C. K. & Schiff, R., Sep 1 2017, In : Clinical Cancer Research. 23, 17, p. 5123-5134 12 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Mutation
Cell Line
Small Interfering RNA
Therapeutics
12 Citations (Scopus)
Hemodynamics
Endocardium
Confocal Microscopy
Electron Scanning Microscopy
Proteomics
4 Citations (Scopus)
Myofibrils
Myocardium
Hemodynamics
Proteomics
Renin-Angiotensin System
100 Citations (Scopus)

Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

Robertson, A. G., Shih, J., Yau, C., Gibb, E. A., Oba, J., Mungall, K. L., Hess, J. M., Uzunangelov, V., Walter, V., Danilova, L., Lichtenberg, T. M., Kucherlapati, M., Kimes, P. K., Tang, M., Penson, A., Babur, O., Akbani, R., Bristow, C. A., Hoadley, K. A., Iype, L. & 191 others, Chang, M. T., Abdel-Rahman, M. H., Akbani, R., Ally, A., Auman, J. T., Babur, O., Balasundaram, M., Balu, S., Benz, C., Beroukhim, R., Birol, I., Bodenheimer, T., Bowen, J., Bowlby, R., Bristow, C. A., Brooks, D., Carlsen, R., Cebulla, C. M., Chang, M. T., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cibulskis, C., Cibulskis, K., Cope, L., Coupland, S. E., Danilova, L., Defreitas, T., Demchok, J. A., Desjardins, L., Dhalla, N., Esmaeli, B., Felau, I., Ferguson, M. L., Frazer, S., Gabriel, S. B., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Gershenwald, J. E., Getz, G., Gibb, E. A., Griewank, K. G., Grimm, E. A., Hayes, D. N., Hegde, A. M., Heiman, D. I., Helsel, C., Hess, J. M., Hoadley, K. A., Hobensack, S., Holt, R. A., Hoyle, A. P., Hu, X., Hutter, C. M., Jager, M. J., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Kandoth, C., Kasaian, K., Kim, J., Kimes, P. K., Kucherlapati, M., Kucherlapati, R., Lander, E., Lawrence, M. S., Lazar, A. J., Lee, S., Leraas, K. M., Lichtenberg, T. M., Lin, P., Liu, J., Liu, W., Mills, G., Lu, Y., Iype, L., Ma, Y., Mahadeshwar, H. S., Mariani, O., Marra, M. A., Mayo, M., Meier, S., Meng, S., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Mose, L. E., Mungall, A. J., Mungall, K. L., Murray, B. A., Naresh, R., Noble, M. S., Oba, J., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Penson, A., Perou, C. M., Pihl, T., Pilarski, R., Protopopov, A., Radenbaugh, A., Rai, K., Ramirez, N. C., Ren, X., Reynolds, S. M., Roach, J., Robertson, A. G., Roman-Roman, S., Roszik, J., Sadeghi, S., Saksena, G., Sastre, X., Schadendorf, D., Schein, J. E., Schoenfield, L., Schumacher, S. E., Seidman, J., Seth, S., Sethi, G., Sheth, M., Shi, Y., Shields, C., Shih, J., Shmulevich, I., Simons, J. V., Singh, A. D., Sipahimalani, P., Skelly, T., Sofia, H., Soloway, M. G., Song, X., Stern, M. H., Stuart, J., Sun, Q., Sun, H., Tam, A., Tan, D., Tang, M., Tang, J., Tarnuzzer, R., Taylor, B. S., Thiessen, N., Thorsson, V., Tse, K., Uzunangelov, V., Veluvolu, U., Verhaak, R. G. W., Voet, D., Walter, V., Wan, Y., Wang, Z., Weinstein, J. N., Wilkerson, M. D., Williams, M. D., Wise, L., Woodman, S. E., Wong, T., Wu, Y., Yang, L., Yang, L., Yau, C., Zenklusen, J. C., Zhang, J., Zhang, H., Zmuda, E., Cherniack, A. D., Benz, C., Mills, G. B., Verhaak, R. G. W., Griewank, K. G., Felau, I., Zenklusen, J. C., Gershenwald, J. E., Schoenfield, L., Lazar, A. J., Abdel-Rahman, M. H., Roman-Roman, S., Stern, M. H., Cebulla, C. M., Williams, M. D., Jager, M. J., Coupland, S. E., Esmaeli, B., Kandoth, C. & Woodman, S. E., Aug 14 2017, In : Cancer Cell. 32, 2, p. 204-220.e15

Research output: Contribution to journalArticle

Monosomy
DNA Methylation
Mutation
Uveal melanoma
Neoplasms
2 Citations (Scopus)

Integrative molecular network analysis identifies emergent enzalutamide resistance mechanisms in prostate cancer

King, C. J., Woodward, J., Schwartzman, J., Coleman, D. J., Lisac, R., Wang, N. J., Hook, K. V., Gao, L., Urrutia, J., Dane, M. A., Heiser, L. & Alumkal, J., Jan 1 2017, In : Oncotarget. 8, 67, p. 111084-111095 12 p.

Research output: Contribution to journalArticle

Castration
Prostatic Neoplasms
Neoplasms
Drug Resistance
Genes
12 Citations (Scopus)

Intraluminal thrombus is associated with early rupture of abdominal aortic aneurysm

Haller, S. J., Crawford, J. D., Courchaine, K. M., Bohannan, C. J., Landry, G., Moneta, G. G., Azarbal, A. & Rugonyi, S., Jan 1 2017, (Accepted/In press) In : Journal of Vascular Surgery.

Research output: Contribution to journalArticle

Abdominal Aortic Aneurysm
Rupture
Thrombosis
Aneurysm
Blood Pressure
12 Citations (Scopus)

In vivo imaging of coral tissue and skeleton with optical coherence tomography

Wangpraseurt, D., Wentzel, C., Jacques, S., Wagner, M. & Kühl, M., Mar 1 2017, In : Journal of the Royal Society Interface. 14, 128, 20161003.

Research output: Contribution to journalArticle

Anthozoa
Optical tomography
Optical Coherence Tomography
Skeleton
Tissue
4 Citations (Scopus)

Modeling gene-wise dependencies improves the identification of drug response biomarkers in cancer studies

Nikolova, O., Moser, R., Kemp, C., Gonen, M. & Margolin, A., May 1 2017, In : Bioinformatics. 33, 9, p. 1362-1369 8 p.

Research output: Contribution to journalArticle

Pharmacological Biomarkers
Biomarkers
Cancer
Drugs
Genes
6 Citations (Scopus)

Modeling subdiffusive light scattering by incorporating the tissue phase function and detector numerical aperture

Post, A. L., Jacques, S., Sterenborg, H. J. C. M., Faber, DI. J. & Van Leeuwen, T. G., 2017, In : Journal of Biomedical Optics. 22, 5, 050501.

Research output: Contribution to journalArticle

numerical aperture
Light scattering
light scattering
Tissue
Detectors
9 Citations (Scopus)

MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance

Farrell, A., Joly, M. M., Allen-Petersen, B. L., Worth, P. J., Lanciault, C., Sauer, D., Link, J., Pelz, C., Heiser, L., Morton, J. P., Muthalagu, N., Hoffman, M. T., Manning, S. L., Pratt, E. D., Kendsersky, N. D., Egbukichi, N., Amery, T. S., Thoma, M. C., Jenny, Z. P., Rhim, A. D. & 5 others, Murphy, D. J., Sansom, O. J., Crawford, H. C., Sheppard, B. & Sears, R., Dec 1 2017, In : Nature Communications. 8, 1, 1728.

Research output: Contribution to journalArticle

Synaptophysin
plastic properties
markers
Plasticity
Tumors
2 Citations (Scopus)

Noninvasive in vivo optical characterization of blood flow and oxygen consumption in the superficial plexus of skin

Liasi, F. T., Samatham, R. & Jacques, S., Nov 1 2017, In : Journal of Biomedical Optics. 22, 11, 115002.

Research output: Contribution to journalArticle

oxygen consumption
blood flow
Skin
Blood
Oxygen
10 Citations (Scopus)

Nucleic acids as cofactors for factor XI and prekallikrein activation: Different roles for high-molecular-weight kininogen

Ivanov, I., Shakhawat, R., Sun, M. F., Dickeson, S. K., Puy, C., McCarty, O., Gruber, A., Matafonov, A. & Gailani, D., 2017, In : Thrombosis and Haemostasis. 117, 4, p. 671-681 11 p.

Research output: Contribution to journalArticle

High Molecular Weight Kininogens
Factor XI
Prekallikrein
Nucleic Acids
Factor XIIa
7 Citations (Scopus)

Optimizing fresh specimen staining for rapid identification of tumor biomarkers during surgery

Barth, C. W., Schaefer, J. M., Rossi, V. M., Davis, S. C. & Gibbs, S., 2017, In : Theranostics. 7, 19, p. 4722-4734 13 p.

Research output: Contribution to journalArticle

Tumor Biomarkers
Staining and Labeling
Neoplasms
Area Under Curve
Segmental Mastectomy
5 Citations (Scopus)

Pathway-enriched gene signature associated with 53BP1 response to PARP inhibition in triple-negative breast cancer

Hassan, S., Esch, A., Liby, T., Gray, J. & Heiser, L., Dec 1 2017, In : Molecular Cancer Therapeutics. 16, 12, p. 2892-2901 10 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Genes
DNA Damage
Biomarkers
Breast Neoplasms
3 Citations (Scopus)

PathwayMapper: A collaborative visual web editor for cancer pathways and genomic data

Bahceci, I., Dogrusoz, U., La, K. C., Babur, O., Gao, J. & Schultz, N., Jul 15 2017, In : Bioinformatics. 33, 14, p. 2238-2240 3 p.

Research output: Contribution to journalArticle

Genomics
Pathway
Cancer
Genes
Web browsers
11 Citations (Scopus)

Poly(A)-ClickSeq: Click-chemistry for next-generation 3'-end sequencing without RNA enrichment or fragmentation

Routh, A., Ji, P., Jaworski, E., Xia, Z., Li, W. & Wagner, E. J., Jul 1 2017, In : Nucleic Acids Research. 45, 12, e112.

Research output: Contribution to journalArticle

Click Chemistry
RNA Sequence Analysis
Poly A
Polyadenylation
RNA
29 Citations (Scopus)

Polyphosphate nanoparticles on the platelet surface trigger contact system activation

Verhoef, J. J. F., Barendrecht, A. D., Nickel, K. F., Dijkxhoorn, K., Kenne, E., Labberton, L., McCarty, O., Schiffelers, R., Heijnen, H. F., Hendrickx, A. P., Schellekens, H., Fens, M. H., De Maat, S., Renné, T. & Maas, C., Mar 23 2017, In : Blood. 129, 12, p. 1707-1717 11 p.

Research output: Contribution to journalArticle

Polyphosphates
Platelets
Nanoparticles
Blood Platelets
Chemical activation

Potentiation of TRAP-6-induced platelet dense granule release by blockade of P2Y12 signaling with MRS2395

Mitrugno, A., Rigg, R. A., Laschober, N. B., Ngo, A. T. P., Pang, J., Williams, C. D., Aslan, J. & McCarty, O., May 20 2017, (Accepted/In press) In : Platelets. p. 1-12 12 p.

Research output: Contribution to journalArticle

Blood Platelets
thrombin receptor peptide SFLLRNP
Hemostatics
Adenosine Diphosphate
Phosphorylation
4 Citations (Scopus)

Prophetic Granger Causality to infer gene regulatory networks

Carlin, D. E., Paull, E. O., Graim, K., Wong, C. K., Bivol, A., Ryabinin, P., Ellrott, K., Sokolov, A. & Stuart, J. M., Dec 1 2017, In : PLoS One. 12, 12, e0170340.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Causality
Genes
Electric wiring
Bioinformatics
3 Citations (Scopus)

Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics

Hafner, M., Heiser, L., Williams, E. H., Niepel, M., Wang, N. J., Korkola, J., Gray, J. & Sorger, P. K., Nov 7 2017, In : Scientific data. 4, 170166.

Research output: Contribution to journalArticle

Breast Cancer
quantification
Quantification
Cancer
Drugs
7 Citations (Scopus)

Quantitating morphological changes in biological samples during scanning electron microscopy sample preparation with correlative super-resolution microscopy

Zhang, Y., Huang, T., Jorgens, D., Nickerson, A., Lin, L. J., Pelz, J., Gray, J., Lopez, C. & Nan, X., May 1 2017, In : PLoS One. 12, 5, e0176839.

Research output: Contribution to journalArticle

Electron Scanning Microscopy
Electron microscopy
Microscopy
microscopy
Drying
2 Citations (Scopus)

Quantitative, in situ analysis of mRNAs and proteins with subcellular resolution

Kwon, S., Chin, K-Y., Nederlof, M. & Gray, J., Dec 1 2017, In : Scientific Reports. 7, 1, 16459.

Research output: Contribution to journalArticle

Messenger RNA
Breast Neoplasms
Fluorescent Antibody Technique
Proteins
RNA
74 Citations (Scopus)

Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis

Tsujikawa, T., Kumar, S., Borkar, R. N., Azimi, V., Thibault, G., Chang, Y. H., Balter, A., Kawashima, R., Choe, G., Sauer, D., El Rassi, E., Clayburgh, D., Kulesz-Martin, M., Lutz, E. R., Zheng, L., Jaffee, E. M., Leyshock, P., Margolin, A., Mori, M. T., Gray, J. & 2 others, Flint, P. & Coussens, L., Apr 4 2017, In : Cell Reports. 19, 1, p. 203-217 15 p.

Research output: Contribution to journalArticle

Tumors
Immunohistochemistry
Tissue
Biomarkers
Papillomaviridae
2 Citations (Scopus)

recount workflow: Accessing over 70,000 human RNA-seq samples with Bioconductor

Collado-Torres, L., Nellore, A. & Jaffe, A. E., 2017, In : F1000Research. 6, 1558.

Research output: Contribution to journalArticle

Workflow
Genes
RNA
Metadata
Websites

Removal of the C-terminal domains of ADAMTS13 by activated coagulation factor XI induces platelet adhesion on endothelial cells under flow conditions

Garland, K. S., Reitsma, S. E., Shirai, T., Zilberman-Rudenko, J., Tucker, E., Gailani, D., Gruber, A., McCarty, O. & Puy, C., Jan 1 2017, In : Frontiers in Medicine. 4, DEC, 232.

Research output: Contribution to journalArticle

Open Access
Factor XIa
Factor XI
von Willebrand Factor
Blood Platelets
Endothelial Cells
17 Citations (Scopus)

Selective factor VIII activation by the tissue factor–factor VIIa–factor Xa complex

Kamikubo, Y., Mendolicchio, G. L., Zampolli, A., Marchese, P., Rothmeier, A. S., Orje, J. N., Gale, A. J., Krishnaswamy, S., Gruber, A., Østergaard, H., Petersen, L. C., Ruf, W. & Ruggeri, Z. M., Oct 5 2017, In : Blood. 130, 14, p. 1661-1670 10 p.

Research output: Contribution to journalArticle

Factor VIII
Thromboplastin
Chemical activation
Tissue
Thrombin
9 Citations (Scopus)

Superresolution imaging of clinical formalin fixed paraffin embedded breast cancer with single molecule localization microscopy

Creech, M. K., Wang, J., Nan, X. & Gibbs, S., Jan 18 2017, In : Scientific Reports. 7, 40766.

Research output: Contribution to journalArticle

Paraffin
Formaldehyde
Breast Neoplasms
Nuclear Lamina
Astigmatism
15 Citations (Scopus)

Targeted treatment of metastatic breast cancer by PLK1 siRNA delivered by an antioxidant nanoparticle platform

Morry, J., Ngamcherdtrakul, W., Gu, S., Reda, M., Castro, D. J., Sangvanich, T., Gray, J. & Yantasee, W., Apr 1 2017, In : Molecular Cancer Therapeutics. 16, 4, p. 763-772 10 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Nanoparticles
Small Interfering RNA
Antioxidants
Breast Neoplasms
58 Citations (Scopus)

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

Keenan, A. B., Jenkins, S. L., Jagodnik, K. M., Koplev, S., He, E., Torre, D., Wang, Z., Dohlman, A. B., Silverstein, M. C., Lachmann, A., Kuleshov, M. V., Ma'ayan, A., Stathias, V., Terryn, R., Cooper, D., Forlin, M., Koleti, A., Vidovic, D., Chung, C., Schürer, S. C. & 87 others, Vasiliauskas, J., Pilarczyk, M., Shamsaei, B., Fazel, M., Ren, Y., Niu, W., Clark, N. A., White, S., Mahi, N., Zhang, L., Kouril, M., Reichard, J. F., Sivaganesan, S., Medvedovic, M., Meller, J., Koch, R. J., Birtwistle, M. R., Iyengar, R., Sobie, E. A., Azeloglu, E. U., Kaye, J., Osterloh, J., Haston, K., Kalra, J., Finkbiener, S., Li, J., Milani, P., Adam, M., Escalante-Chong, R., Sachs, K., Lenail, A., Ramamoorthy, D., Fraenkel, E., Daigle, G., Hussain, U., Coye, A., Rothstein, J., Sareen, D., Ornelas, L., Banuelos, M., Mandefro, B., Ho, R., Svendsen, C. N., Lim, R. G., Stocksdale, J., Casale, M. S., Thompson, T. G., Wu, J., Thompson, L. M., Dardov, V., Venkatraman, V., Matlock, A., Van Eyk, J. E., Jaffe, J. D., Papanastasiou, M., Subramanian, A., Golub, T. R., Erickson, S. D., Fallahi-Sichani, M., Hafner, M., Gray, N. S., Lin, J. R., Mills, C. E., Muhlich, J. L., Niepel, M., Shamu, C. E., Williams, E. H., Wrobel, D., Sorger, P. K., Heiser, L., Gray, J., Korkola, J., Mills, G., LaBarge, M., Feiler, H., Dane, M. A., Bucher, E., Nederlof, M., Sudar, D., Gross, S., Kilburn, D. F., Smith, R., Devlin, K., Margolis, R., Derr, L., Lee, A. & Pillai, A., Jan 1 2017, (Accepted/In press) In : Cell Systems.

Research output: Contribution to journalArticle

Cataloging
Libraries
Inborn Genetic Diseases
Molecular Imaging
Neurodegenerative Diseases
22 Citations (Scopus)

Thrombogenicity of flow diverters in an ex vivo shunt model: Effect of phosphorylcholine surface modification

Hagen, M. W., Girdhar, G., Wainwright, J. & Hinds, M., Oct 1 2017, In : Journal of NeuroInterventional Surgery. 9, 10, p. 1006-1011 6 p.

Research output: Contribution to journalArticle

Phosphorylcholine
Equipment and Supplies
Blood Platelets
Technology
clopidogrel
10 Citations (Scopus)

TumorMap: Exploring the molecular similarities of cancer samples in an interactive portal

Newton, Y., Novak, A. M., Swatloski, T., McColl, D. C., Chopra, S., Graim, K., Weinstein, A. S., Baertsch, R., Salama, S. R., Ellrott, K., Chopra, M., Goldstein, T. C., Haussler, D., Morozova, O. & Stuart, J. M., Nov 1 2017, In : Cancer Research. 77, 21, p. e111-e114

Research output: Contribution to journalArticle

Neoplasms
Atlases
Genome
Technology

Using tablet-based technology to deliver time-efficient ototoxicity monitoring

Brungart, D., Schurman, J., Konrad-Martin, D., Watts, K., Buckey, J., Clavier, O., Jacobs, P., Gordon, S. & Dille, M. F., Sep 11 2017, (Accepted/In press) In : International Journal of Audiology. p. 1-9 9 p.

Research output: Contribution to journalArticle

Tablets
monitoring
Technology
Cost of Illness
Standard of Care
5 Citations (Scopus)

Versatile Interacting Peptide (VIP) Tags for Labeling Proteins with Bright Chemical Reporters

Zane, H. K., Doh, J. K., Enns, C. & Beatty, K., Mar 2 2017, In : ChemBioChem. 18, 5, p. 470-474 5 p.

Research output: Contribution to journalArticle

Labeling
Peptides
Fluorophores
Proteins
Quantum Dots
2016
112 Citations (Scopus)

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds

Bruna, A., Rueda, O. M., Greenwood, W., Batra, A. S., Callari, M., Batra, R. N., Pogrebniak, K., Sandoval, J., Cassidy, J. W., Tufegdzic-Vidakovic, A., Sammut, S. J., Jones, L., Provenzano, E., Baird, R., Eirew, P., Hadfield, J., Eldridge, M., McLaren-Douglas, A., Barthorpe, A., Lightfoot, H. & 10 others, O'Connor, M. J., Gray, J., Cortes, J., Baselga, J., Marangoni, E., Welm, A. L., Aparicio, S., Serra, V., Garnett, M. J. & Caldas, C., Sep 22 2016, In : Cell. 167, 1, p. 260-274.e22

Research output: Contribution to journalArticle

Tumors
Breast Neoplasms
Neoplasms
Heterografts
Cells
3 Citations (Scopus)

A Geodesics-Based Surface Parameterization to Assess Aneurysm Progression

Phan, L., Courchaine, K., Azarbal, A., Vorp, D., Grimm, C. & Rugonyi, S., May 1 2016, In : Journal of Biomechanical Engineering. 138, 5, 054503.

Research output: Contribution to journalArticle

Abdominal Aortic Aneurysm
Parameterization
Aneurysm
Strain relaxation
Rupture
44 Citations (Scopus)

Architecture of fully occupied GluA2 AMPA receptor-TARP complex elucidated by cryo-EM

Zhao, Y., Chen, S., Yoshioka, C., Baconguis, I. & Gouaux, E., Jul 1 2016, In : Nature. 536, 7614, p. 108-111 4 p.

Research output: Contribution to journalArticle

Cryoelectron Microscopy
AMPA Receptors
Proteins
Ligands
Ion Channels
1 Citation (Scopus)

ARTIK-52 induces replication-dependent DNA damage and p53 activation exclusively in cells of prostate and breast cancer origin

Fleyshman, D., Cheney, P., Ströse, A., Mudambi, S., Safina, A., Commane, M., Purmal, A., Morgan, K., Wang, N. J., Gray, J., Spellman, P., Issaeva, N. & Gurova, K., Feb 1 2016, In : Cell Cycle. 15, 3, p. 455-470 16 p.

Research output: Contribution to journalArticle

Androgen Receptors
DNA Damage
Prostatic Neoplasms
Breast Neoplasms
Androgens
12 Citations (Scopus)
Loneliness
Contact sensors
Health
Sensors
Aptitude
21 Citations (Scopus)

Assessment of neonatal platelet adhesion, activation, and aggregation

Baker-Groberg, S. M., Lattimore, S., Recht, M., McCarty, O. & Haley, K., 2016, (Accepted/In press) In : Journal of Thrombosis and Haemostasis.

Research output: Contribution to journalArticle

Platelet Activation
Platelet Aggregation
Blood Platelets
Immunoreceptor Tyrosine-Based Activation Motif
Thrombin Receptors
4 Citations (Scopus)

Bioactive Anti-Thrombotic Modification of Decellularized Matrix for Vascular Applications

Glynn, J. J. & Hinds, M., Jun 22 2016, In : Advanced healthcare materials. 5, 12, p. 1439-1446 8 p.

Research output: Contribution to journalArticle

Thrombomodulin
Blood Vessels
Heparin
Proteins
Protein C
7 Citations (Scopus)

Biophysical comparison of ATP synthesis mechanisms shows a kinetic advantage for the rotary process

Anandakrishnan, R., Zhang, Z., Donovan-Maiye, R. & Zuckerman, D., Oct 4 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 40, p. 11220-11225 6 p.

Research output: Contribution to journalArticle

Open Access
Adenosine Triphosphate
Adenosine Triphosphatases
Thermodynamics
Membrane Potentials
Protons
5 Citations (Scopus)

Biorheology of Platelet Activation in the Bloodstream Distal to Thrombus Formation

Zilberman-Rudenko, J., Itakura, A., Maddala, J., Baker-Groberg, S. M., Vetter, R., Tucker, E., Gruber, A., Gerdes, C. & McCarty, O., May 25 2016, (Accepted/In press) In : Cellular and Molecular Bioengineering. p. 1-13 13 p.

Research output: Contribution to journalArticle

Platelets
Platelet Activation
Activation
Thrombosis
Chemical activation
7 Citations (Scopus)

Cellular androgen content influences enzalutamide agonism of F877L mutant androgen receptor

Coleman, D. J., Van Hook, K., King, C. J., Schwartzman, J., Lisac, R., Urrutia, J., Sehrawat, A., Woodward, J., Wang, N. J., Gulati, R., Thomas, G., Beer, T. T., Gleave, M., Korkola, J., Gao, L., Heiser, L. & Alumkal, J., 2016, In : Oncotarget. 7, 26, p. 40690 1 p.

Research output: Contribution to journalArticle

Androgen Receptors
Androgens
Castration
Prostatic Neoplasms
MDV 3100
2 Citations (Scopus)

Changes in dynamic embryonic heart wall motion in response to outflow tract banding measured using video densitometry

Stovall, S., Midgett, M., Thornburg, K. & Rugonyi, S., Nov 1 2016, In : Journal of Biomedical Optics. 21, 11, 116003.

Research output: Contribution to journalArticle

blood flow
Optical microscopy
biodynamics
microscopy
heart diseases
6 Citations (Scopus)

Changes in single-molecule integrin dynamics linked to local cellular behavior

Jaqaman, K., Galbraith, J., Davidson, M. W. & Galbraith, C., May 15 2016, In : Molecular Biology of the Cell. 27, 10, p. 1561-1569 9 p.

Research output: Contribution to journalArticle

Integrins
Molecular Dynamics Simulation
Molecular Imaging
Microscopy
Light
22 Citations (Scopus)

Characterizing the immune microenvironment in high-risk ductal carcinoma in situ of the breast

Campbell, M. J., Baehner, F., O’Meara, T., Ojukwu, E., Han, B., Mukhtar, R., Tandon, V., Endicott, M., Zhu, Z., Wong, J., Krings, G., Au, A., Gray, J. & Esserman, L., Oct 26 2016, (Accepted/In press) In : Breast Cancer Research and Treatment. p. 1-12 12 p.

Research output: Contribution to journalArticle

Carcinoma, Intraductal, Noninfiltrating
Breast
Recurrence
Proliferating Cell Nuclear Antigen
HLA-DR Antigens
16 Citations (Scopus)

Coagulation Factor XI Promotes Distal Platelet Activation and Single Platelet Consumption in the Bloodstream Under Shear Flow

Zilberman-Rudenko, J., Itakura, A., Wiesenekker, C. P., Vetter, R., Maas, C., Gailani, D., Tucker, E., Gruber, A., Gerdes, C. & McCarty, O., Jan 14 2016, (Accepted/In press) In : Arteriosclerosis, Thrombosis, and Vascular Biology.

Research output: Contribution to journalArticle

Factor XI
Platelet Activation
Thrombosis
Blood Platelets
Thrombin
17 Citations (Scopus)

Coated platelets function in platelet-dependent fibrin formation via integrin αIIbβ3 and transglutaminase factor XIII

Mattheij, N. J. A., Swieringa, F., Mastenbroek, T. G., Berny-Lang, M. A., May, F., Baaten, C. C. F. M. J., van der Meijden, P. E. J., Henskens, Y. M. C., Beckers, E. A. M., Suylen, D. P. L., Nolte, M. W., Hackeng, T. M., McCarty, O., Heemskerk, J. W. M. & Cosemans, J. M. E. M., Mar 31 2016, In : Haematologica. 101, 4, p. 427-436 10 p.

Research output: Contribution to journalArticle

Factor XIII
Transglutaminases
Fibrin
Integrins
Blood Platelets