Research Output

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Review article
2019

CFTR modulator theratyping: Current status, gaps and future directions

Clancy, J. P., Cotton, C. U., Donaldson, S. H., Solomon, G. M., VanDevanter, D. R., Boyle, M. P., Gentzsch, M., Nick, J. A., Illek, B., Wallenburg, J. C., Sorscher, E. J., Amaral, M. D., Beekman, J. M., Naren, A. P., Bridges, R. J., Thomas, P. J., Cutting, G., Rowe, S., Durmowicz, A. G., Mense, M. & 8 others, Boeck, K. D., Skach, W., Penland, C., Joseloff, E., Bihler, H., Mahoney, J., Borowitz, D. & Tuggle, K. L., Jan 2019, In : Journal of Cystic Fibrosis. 18, 1, p. 22-34 13 p.

Research output: Contribution to journalReview article

37 Scopus citations
Open Access
2017

Parasite polyamines as pharmaceutical targets

Roberts, S. & Ullman, B., Jan 1 2017, In : Current Pharmaceutical Design. 23, 23, p. 3325-3341 17 p.

Research output: Contribution to journalReview article

7 Scopus citations
2014

Fluorescence spectroscopy of rhodopsins: Insights and approaches

Alexiev, U. & Farrens, D. L., May 2014, In : Biochimica et Biophysica Acta - Bioenergetics. 1837, 5, p. 694-709 16 p.

Research output: Contribution to journalReview article

43 Scopus citations
2013
60 Scopus citations

Pharmacological rescue of trafficking-impaired ATP-sensitive potassium channels

Martin, G. M., Chen, P. C., Devaraneni, P. & Shyng, S. L., Dec 1 2013, In : Frontiers in Physiology. 4 DEC, Article 386.

Research output: Contribution to journalReview article

30 Scopus citations

Role of the retinal vascular endothelial cell in ocular disease

Bharadwaj, A. S., Appukuttan, B., Wilmarth, P. A., Pan, Y., Stempel, A. J., Chipps, T. J., Benedetti, E. E., Zamora, D. O., Choi, D., David, L. L. & Smith, J. R., Jan 1 2013, In : Progress in Retinal and Eye Research. 32, 1, p. 102-180 79 p.

Research output: Contribution to journalReview article

69 Scopus citations
2012
17 Scopus citations

Mapping the growth hormone-Stat5b-IGF-I transcriptional circuit

Rotwein, P., Apr 2012, In : Trends in Endocrinology and Metabolism. 23, 4, p. 186-193 8 p.

Research output: Contribution to journalReview article

65 Scopus citations

Purine salvage in Leishmania: Complex or simple by design?

Boitz, J. M., Ullman, B., Jardim, A. & Carter, N. S., Aug 1 2012, In : Trends in Parasitology. 28, 8, p. 345-352 8 p.

Research output: Contribution to journalReview article

43 Scopus citations

Targeting the fanconi anemia pathway to identify tailored anticancer therapeutics

Jenkins, C., Kan, J. & Hoatlin, M. E., Dec 1 2012, In : Anemia. 2012, 481583.

Research output: Contribution to journalReview article

12 Scopus citations
2011

Protein folding and quality control in the endoplasmic reticulum: Recent lessons from yeast and mammalian cell systems

Brodsky, J. L. & Skach, W. R., Aug 1 2011, In : Current Opinion in Cell Biology. 23, 4, p. 464-475 12 p.

Research output: Contribution to journalReview article

139 Scopus citations
2009

At the crossroads of homoeostasis and disease: Roles of the PACS proteins in membrane traffic and apoptosis

Youker, R. T., Shinde, U., Day, R. & Thomas, G., Jul 1 2009, In : Biochemical Journal. 421, 1, p. 1-15 15 p.

Research output: Contribution to journalReview article

43 Scopus citations

Cellular mechanisms of membrane protein folding

Skach, W. R., Jun 1 2009, In : Nature Structural and Molecular Biology. 16, 6, p. 606-612 7 p.

Research output: Contribution to journalReview article

83 Scopus citations

Molecular biology, genetics and biochemistry of the repulsive guidance molecule family

Severyn, C. J., Shinde, U. & Rotwein, P., Sep 15 2009, In : Biochemical Journal. 422, 3, p. 393-403 11 p.

Research output: Contribution to journalReview article

42 Scopus citations
2007

Insulin-like growth factor binding protein-5 in osteogenesis: Facilitator or inhibitor?

Mukherjee, A. & Rotwein, P., Jun 1 2007, In : Growth Hormone and IGF Research. 17, 3, p. 179-185 7 p.

Research output: Contribution to journalReview article

24 Scopus citations
2006

Molecular mechanisms of aquaporin biogenesis by the endoplasmic reticulum Sec61 translocon

Pitonzo, D. & Skach, W. R., Aug 1 2006, In : Biochimica et Biophysica Acta - Biomembranes. 1758, 8, p. 976-988 13 p.

Research output: Contribution to journalReview article

33 Scopus citations
2005

Molecular physiology, pathology, and regulation of the growth hormone/insulin-like growth factor-I system

Woelfle, J., Chia, D. J., Massart-Schlesinger, M. B., Moyano, P. & Rotwein, P., Mar 1 2005, In : Pediatric Nephrology. 20, 3 SPEC. ISS., p. 295-302 8 p.

Research output: Contribution to journalReview article

37 Scopus citations

γN-crystallin and the evolution of the βγ-crystallin superfamily in vertebrates

Wistow, G., Wyatt, K., David, L., Gao, C., Bateman, O., Bernstein, S., Tomarev, S., Segovia, L., Slingsby, C. & Vihtelic, T., May 1 2005, In : FEBS Journal. 272, 9, p. 2276-2291 16 p.

Research output: Contribution to journalReview article

73 Scopus citations
2004

Biogenesis of CFTR and other polytopic membrane proteins: New roles for the ribosome-translocon complex

Sadlish, H. & Skach, W. R., Dec 1 2004, In : Journal of Membrane Biology. 202, 3, p. 115-126 12 p.

Research output: Contribution to journalReview article

34 Scopus citations

Mini-review: Estrogen action in the uterus and insulin-like growth factor-I

Moyano, P. & Rotwein, P., Dec 2004, In : Growth Hormone and IGF Research. 14, 6, p. 431-435 5 p.

Research output: Contribution to journalReview article

24 Scopus citations

The viral infectivity factor (Vif) of HIV-1 unveiled

Rose, K. M., Marin, M., Kozak, S. L. & Kabat, D., Jun 1 2004, In : Trends in Molecular Medicine. 10, 6, p. 291-297 7 p.

Research output: Contribution to journalReview article

45 Scopus citations
2003

Cell surface receptors for gammaretroviruses

Tailor, C. S., Lavillette, D., Marin, M. & Kabat, D., Aug 15 2003, In : Current topics in microbiology and immunology. 281, p. 29-106 78 p.

Research output: Contribution to journalReview article

60 Scopus citations

Insulin-like growth factor action and skeletal muscle growth, an in vivo perspective

Rotwein, P., Dec 2003, In : Growth Hormone and IGF Research. 13, 6, p. 303-305 3 p.

Research output: Contribution to journalReview article

18 Scopus citations
2002

Chapter 3 Interactions between the cell cycle and the myogenic program

Huang, J. & Thayer, M. J., Dec 1 2002, In : Advances in Developmental Biology and Biochemistry. 11, C, p. 53-74 22 p.

Research output: Contribution to journalReview article

2 Scopus citations

Molecular mechanism of P-glycoprotein assembly into cellular membranes

Anthony, V. & Skach, W. R., Oct 1 2002, In : Current Protein and Peptide Science. 3, 5, p. 485-501 17 p.

Research output: Contribution to journalReview article

24 Scopus citations
2001

Foci on Fanconi

Hoatlin, M. & Reuter, T., Jan 1 2001, In : Trends in Molecular Medicine. 7, 6, p. 237-239 3 p.

Research output: Contribution to journalReview article

4 Scopus citations
2000

Drug uptake via nutrient transporters in Trypanosoma brucei

Hasne, M. P. & Barrett, M. P., Nov 1 2000, In : Journal of Applied Microbiology. 89, 4, p. 697-701 5 p.

Research output: Contribution to journalReview article

16 Scopus citations
1996

Cell biology of the prion protein

Harris, D. A., Gorodinsky, A., Lehmann, S., Moulder, K. & Shyng, S. L., Jan 1 1996, In : Current topics in microbiology and immunology. 207, p. 77-93 17 p.

Research output: Contribution to journalReview article

41 Scopus citations

Crystal structures of Toxoplasma gondii HGXPRTase reveal the catalytic role of a long flexible loop

Schumacher, M. A., Carter, D., Roos, D. S., Ullman, B. & Brennan, R. G., Oct 1 1996, In : Nature Structural Biology. 3, 10, p. 881-887 7 p.

Research output: Contribution to journalReview article

93 Scopus citations

Water transport across mammalian cell membranes

Verkman, A. S., Van Hoek, A. N., Ma, T., Frigeri, A., Skach, W. R., Mitra, A., Tamarappoo, B. K. & Farinas, J., Jan 1996, In : American Journal of Physiology - Cell Physiology. 270, 1 39-1, p. C12-C30

Research output: Contribution to journalReview article

261 Scopus citations
1995

Amplified and tissue-directed expression of retroviral vectors using ping-pong techniques

Hoatlin, M. E., Kozak, S. L., Spiro, C. & Kabat, D., Mar 1 1995, In : Journal of Molecular Medicine. 73, 3, p. 113-120 8 p.

Research output: Contribution to journalReview article

13 Scopus citations

Host-range control of a retroviral disease: Friend erythroleukemia

Hoatlin, M. E. & Kabat, D., Feb 1995, In : Trends in microbiology. 3, 2, p. 51-57 7 p.

Research output: Contribution to journalReview article

37 Scopus citations
1994

Cell surface receptor for ecotropic host-range mouse retroviruses: a cationic amino acid transporter.

Kavanaugh, M. P., Wang, H., Boyd, C. A., North, R. A. & Kabat, D., 1994, In : Archives of virology. Supplementum. 9, p. 485-494 10 p.

Research output: Contribution to journalReview article

9 Scopus citations

The structural and functional organization of intramolecular chaperones: The N-terminal propeptides which mediate protein folding

Shinde, U. & Inouye, M., Apr 1994, In : Journal of Biochemistry. 115, 4, p. 629-636 8 p.

Research output: Contribution to journalReview article

49 Scopus citations
1993

Polyamine and pentamidine metabolism in African trypanosomes

Berger, B. J., Carter, N. S. & Fairlamb, A. H., Sep 1993, In : Acta Tropica. 54, 3-4, p. 215-224 10 p.

Research output: Contribution to journalReview article

22 Scopus citations
1991

Structure, evolution, expression and regulation of insulin-like growth factors i and II

Rotwein, P., Jan 1 1991, In : Growth Factors. 5, 1, p. 3-18 16 p.

Research output: Contribution to journalReview article

226 Scopus citations
1989

Molecular biology of Friend viral erythroleukemia.

Kabat, D., Dec 1 1989, In : Current topics in microbiology and immunology. 148, p. 1-42 42 p.

Research output: Contribution to journalReview article

140 Scopus citations
1987

Selenite cataract: A review

Shearer, T. R., David, L. L. & Anderson, R. S., Jan 1 1987, In : Current Eye Research. 6, 2, p. 289-300 12 p.

Research output: Contribution to journalReview article

73 Scopus citations
1984

Pyrazolopyrimidine Metabolism in Parasitic Protozoa

Ullman, B., Sep 1984, In : Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 1, 5, p. 194-203 10 p.

Research output: Contribution to journalReview article

25 Scopus citations
1982

Diagnosis and management of hypoglycemic disorders in adults.

Rotwein, P. S., Giddings, S. J. & Permutt, M. A., Dec 1 1982, In : Special topics in endocrinology and metabolism. 3, p. 87-115 29 p.

Research output: Contribution to journalReview article

4 Scopus citations
1975

The thalassemias: model for analysis of quantitative gene control.

Kabat, D. & Koler, R. D., Jan 1 1975, In : Advances in Human Genetics. 5, p. 157-222 66 p.

Research output: Contribution to journalReview article

3 Scopus citations
1972

Gene selection in hemoglobin and in antibody-synthesizing cells

Kabat, D., Jan 1 1972, In : Science. 175, 4018, p. 134-140 7 p.

Research output: Contribution to journalReview article

29 Scopus citations