Research Output

2020

Alpha-glucosidase inhibitors alter gut microbiota and ameliorate collagen-induced arthritis

Zhang, L., Song, P., Zhang, X., Metea, C., Schleisman, M., Karstens, L., Leung, E., Zhang, J., Xu, Q., Liu, Y., Asquith, M. & Chu, C. Q., Jan 1 2020, In : Frontiers in Pharmacology. 10, 01684.

Research output: Contribution to journalArticle

Open Access

Analysis of IL-22 and Th22 cells by flow cytometry in systemic lupus erythematosus

Ye, Z., Zhao, L., Gao, Q., Jiang, Y., Jiang, Z. & Chu, C. Q., Jan 1 2020, Methods in Molecular Biology. Humana Press Inc., p. 29-42 14 p. (Methods in Molecular Biology; vol. 2108).

Research output: Chapter in Book/Report/Conference proceedingChapter

A systematic review and network meta-analysis of current and investigational treatments for active ankylosing spondylitis

Deodhar, A., Chakravarty, S. D., Cameron, C., Peterson, S., Hensman, R., Fogarty, S., Spin, P., Kafka, S., Nair, S. & Gensler, L. S., Jan 1 2020, (Accepted/In press) In : Clinical Rheumatology.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Secukinumab Immunogenicity over 52 Weeks in Patients with Psoriatic Arthritis and Ankylosing Spondylitis

Deodhar, A., Gladman, D. D., McInnes, I. B., Spindeldreher, S., Martin, R., Pricop, L., Porter, B., Safi, J., Shete, A. & Bruin, G., Apr 1 2020, In : The Journal of rheumatology. 47, 4, p. 539-547 9 p.

Research output: Contribution to journalArticle

Single-stranded DNA aptamers against TNF and their potential applications

Tao, S., Song, P., Zhang, X., Zhang, L. & Chu, C. Q., Jan 1 2020, Methods in Molecular Biology. Humana Press Inc., p. 181-196 16 p. (Methods in Molecular Biology; vol. 2108).

Research output: Chapter in Book/Report/Conference proceedingChapter

The importance of ultrasound in identifying and differentiating patients with early inflammatory arthritis: A narrative review

Kaeley, G. S., Bakewell, C. & Deodhar, A., Jan 2 2020, In : Arthritis Research and Therapy. 22, 1, 1.

Research output: Contribution to journalReview article

Open Access

Unmet needs in ankylosing spondylitis patients receiving tumour necrosis factor inhibitor therapy; results from a large multinational real-world study

Deodhar, A., Strand, V., Conaghan, P. G., Sullivan, E., Blackburn, S., Tian, H., Gandhi, K., Jugl, S. M. & Alten, R., Mar 2 2020, In : BMC Rheumatology. 4, 1, 19.

Research output: Contribution to journalArticle

Open Access

Use of machine learning techniques in the development and refinement of a predictive model for early diagnosis of ankylosing spondylitis

Deodhar, A., Rozycki, M., Garges, C., Shukla, O., Arndt, T., Grabowsky, T. & Park, Y., Apr 1 2020, In : Clinical Rheumatology. 39, 4, p. 975-982 8 p.

Research output: Contribution to journalArticle

Open Access
2019

2019 Update of the American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis

Ward, M. M., Deodhar, A. A., Gensler, L. S., Dubreuil, M., Yu, D., Khan, M. A., Haroon, N., Borenstein, D., Wang, R., Biehl, A., Fang, M. A., Louie, G., Majithia, V., Ng, B., Bigham, R., Pianin, M., Shah, A. A., Sullivan, N., Turgunbaev, M., Oristaglio, J. & 3 others, Turner, A., Maksymowych, W. P. & Caplan, L., Jan 1 2019, (Accepted/In press) In : Arthritis and Rheumatology.

Research output: Contribution to journalArticle

12 Scopus citations

2019 Update of the American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis

Ward, M. M., Deodhar, A. A., Gensler, L. S., Dubreuil, M., Yu, D., Khan, M. A., Haroon, N., Borenstein, D., Wang, R., Biehl, A., Fang, M. A., Louie, G., Majithia, V., Ng, B., Bigham, R., Pianin, M., Shah, A. A., Sullivan, N., Turgunbaev, M., Oristaglio, J. & 3 others, Turner, A., Maksymowych, W. P. & Caplan, L., Jan 1 2019, (Accepted/In press) In : Arthritis Care and Research.

Research output: Contribution to journalArticle

8 Scopus citations

A Fifty-Two–Week, Randomized, Placebo-Controlled Trial of Certolizumab Pegol in Nonradiographic Axial Spondyloarthritis

Deodhar, A. A., Gensler, L. S., Kay, J., Maksymowych, W. P., Haroon, N., Landewé, R., Rudwaleit, M., Hall, S., Bauer, L., Hoepken, B., de Peyrecave, N., Kilgallen, B. & van der Heijde, D., Jul 1 2019, In : Arthritis and Rheumatology. 71, 7, p. 1101-1111 11 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Controlling for contaminants in low-biomass 16S rRNA gene sequencing experiments

Karstens, L., Asquith, M., Davin, S., Fair, D., Gregory, W. T., Wolfe, A. J., Braun, J. & McWeeney, S., Jul 2019, In : mSystems. 4, 4, e00290-19.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Disruption of Intestinal Homeostasis and Intestinal Microbiota During Experimental Autoimmune Uveitis

Janowitz, C., Nakamura, Y. K., Metea, C., Gligor, A., Yu, W., Karstens, L., Rosenbaum, J. J., Asquith, M. & Lin, P., Jan 2 2019, In : Investigative ophthalmology & visual science. 60, 1, p. 420-429 10 p.

Research output: Contribution to journalArticle

3 Scopus citations
27 Scopus citations

Efficacy and safety of ixekizumab through 52 weeks in two phase 3, randomised, controlled clinical trials in patients with active radiographic axial spondyloarthritis (COAST-V and COAST-W)

Dougados, M., Wei, J. C. C., Landewé, R., Sieper, J., Baraliakos, X., Van Den Bosch, F., Maksymowych, W. P., Ermann, J., Walsh, J. A., Tomita, T., Deodhar, A., Van Der Heijde, D., Li, X., Zhao, F., Bertram, C. C., Gallo, G., Carlier, H. & Gensler, L. S., Jan 1 2019, (Accepted/In press) In : Annals of the rheumatic diseases.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Efficacy and safety of upadacitinib in patients with active ankylosing spondylitis (SELECT-AXIS 1): a multicentre, randomised, double-blind, placebo-controlled, phase 2/3 trial

van der Heijde, D., Song, I. H., Pangan, A. L., Deodhar, A., van den Bosch, F., Maksymowych, W. P., Kim, T. H., Kishimoto, M., Everding, A., Sui, Y., Wang, X., Chu, A. D. & Sieper, J., Dec 7 2019, In : The Lancet. 394, 10214, p. 2108-2117 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Harnessing the power of social media: how can it help in axial spondyloarthritis research?

Reuter, K., Danve, A. & Deodhar, A., Jul 1 2019, In : Current opinion in rheumatology. 31, 4, p. 321-328 8 p.

Research output: Contribution to journalReview article

1 Scopus citations

HLA Alleles Associated With Risk of Ankylosing Spondylitis and Rheumatoid Arthritis Influence the Gut Microbiome

Asquith, M., Sternes, P. R., Costello, M. E., Karstens, L., Diamond, S., Martin, T. M., Li, Z., Marshall, M. S., Spector, T. D., le Cao, K. A., Rosenbaum, J. T. & Brown, M. A., Oct 1 2019, In : Arthritis and Rheumatology. 71, 10, p. 1642-1650 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Incidence rates of inflammatory bowel disease in patients with psoriasis, psoriatic arthritis and ankylosing spondylitis treated with secukinumab: A retrospective analysis of pooled data from 21 clinical trials

Schreiber, S., Colombel, J. F., Feagan, B. G., Reich, K., Deodhar, A. A., McInnes, I. B., Porter, B., Das Gupta, A., Pricop, L. & Fox, T., Apr 1 2019, In : Annals of the rheumatic diseases. 78, 4, p. 473-479 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Ixekizumab for treating ankylosing spondylitis

Kiwalkar, S., Beier, S. & Deodhar, A., Jan 1 2019, In : Immunotherapy. 11, 15, p. 1273-1282 10 p.

Research output: Contribution to journalReview article

Long-term efficacy and safety of secukinumab 150 mg in ankylosing spondylitis: 5-year results from the phase III MEASURE 1 extension study

Baraliakos, X., Braun, J., Deodhar, A. A., Poddubnyy, D., Kivitz, A., Tahir, H., Van Den Bosch, F., Delicha, E. M., Talloczy, Z. & Fierlinger, A., Sep 1 2019, In : RMD Open. 5, 2, e01005.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Long-term safety of secukinumab in patients with moderate-to-severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis: Integrated pooled clinical trial and post-marketing surveillance data

Deodhar, A., Mease, P. J., McInnes, I. B., Baraliakos, X., Reich, K., Blauvelt, A., Leonardi, C., Porter, B., Das Gupta, A., Widmer, A., Pricop, L. & Fox, T., May 2 2019, In : Arthritis Research and Therapy. 21, 1, 111.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Measuring Coaching in Undergraduate Medical Education: the Development and Psychometric Validation of New Instruments

Carney, P. P., Bonura, E. M., Kraakevik, J., Juve, A. M., Kahl, L. & Deiorio, N., May 15 2019, In : Journal of general internal medicine. 34, 5, p. 677-683 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Modified stoke ankylosing spondylitis spinal score as an outcome measure to assess the impact of treatment on structural progression in ankylosing spondylitis

Van Der Heijde, D., Braun, J., Deodhar, A. A., Baraliakos, X., Landewé, R., Richards, H. B., Porter, B. & Readie, A., Mar 1 2019, In : Rheumatology (United Kingdom). 58, 3, p. 388-400 13 p.

Research output: Contribution to journalReview article

Open Access
11 Scopus citations

Older Drugs With Limited Trial Evidence: Are They Worth the Expense?

Hartung, D. M., Cohen, D. M., Deodhar, A. & Bourdette, D. N., Oct 15 2019, In : Annals of internal medicine. 171, 8, p. 601-602 2 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2 Scopus citations

Safety and efficacy of intravenous golimumab in adults with ankylosing spondylitis: Results through 1 year of the GO-ALIVE study

Reveille, J. D., Deodhar, A., Caldron, P. H., Dudek, A., Harrison, D. D., Kim, L., Lo, K. H., Leu, J. H. & Hsia, E. C., Jan 1 2019, In : Journal of Rheumatology. 46, 10, p. 1277-1283 7 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Secukinumab shows sustained efficacy and low structural progression in ankylosing spondylitis: 4-year results from the MEASURE 1 study

Braun, J., Baraliakos, X., Deodhar, A., Poddubnyy, D., Emery, P., Delicha, E. M., Talloczy, Z. & Porter, B., May 1 2019, In : Rheumatology (United Kingdom). 58, 5, p. 859-868 10 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Silencing RORγt in Human CD4+ T cells with CD30 aptamer-RORγt shRNA Chimera

Shi, X., Song, P., Tao, S., Zhang, X. & Chu, C. Q., Dec 1 2019, In : Scientific Reports. 9, 1, 10375.

Research output: Contribution to journalArticle

Open Access

Special Article: 2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis

Singh, J. A., Guyatt, G., Ogdie, A., Gladman, D. D., Deal, C., Deodhar, A. A., Dubreuil, M., Dunham, J., Husni, M. E., Kenny, S., Kwan-Morley, J., Lin, J., Marchetta, P., Mease, P. J., Merola, J. F., Miner, J., Ritchlin, C. T., Siaton, B., Smith, B. J., Van Voorhees, A. S. & 16 others, Jonsson, A. H., Shah, A. A., Sullivan, N., Turgunbaev, M., Coates, L. C., Gottlieb, A., Magrey, M., Nowell, W. B., Orbai, A. M., Reddy, S. M., Scher, J. U., Siegel, E., Siegel, M., Walsh, J. A., Turner, A. S. & Reston, J., Jan 1 2019, In : Arthritis and Rheumatology. 71, 1, p. 5-32 28 p.

Research output: Contribution to journalArticle

38 Scopus citations

Special Article: 2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis

Singh, J. A., Guyatt, G., Ogdie, A., Gladman, D. D., Deal, C., Deodhar, A. A., Dubreuil, M., Dunham, J., Husni, M. E., Kenny, S., Kwan-Morley, J., Lin, J., Marchetta, P., Mease, P. J., Merola, J. F., Miner, J., Ritchlin, C. T., Siaton, B., Smith, B. J., Van Voorhees, A. S. & 16 others, Jonsson, A. H., Shah, A. A., Sullivan, N., Turgunbaev, M., Coates, L. C., Gottlieb, A., Magrey, M., Nowell, W. B., Orbai, A. M., Reddy, S. M., Scher, J. U., Siegel, E., Siegel, M., Walsh, J. A., Turner, A. S. & Reston, J., Jan 1 2019, In : Arthritis Care and Research. 71, 1, p. 2-29 28 p.

Research output: Contribution to journalArticle

32 Scopus citations

Three Multicenter, Randomized, Double-Blind, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Ustekinumab in Axial Spondyloarthritis

Deodhar, A., Gensler, L. S., Sieper, J., Clark, M., Calderon, C., Wang, Y., Zhou, Y., Leu, J. H., Campbell, K., Sweet, K., Harrison, D. D., Hsia, E. C. & van der Heijde, D., Feb 1 2019, In : Arthritis and Rheumatology. 71, 2, p. 258-270 13 p.

Research output: Contribution to journalArticle

39 Scopus citations

Treat-to-target in axial spondyloarthritis: gold standard or fools' gold?

Machado, P. M. & Deodhar, A., Jul 1 2019, In : Current opinion in rheumatology. 31, 4, p. 344-348 5 p.

Research output: Contribution to journalReview article

1 Scopus citations

Unmet needs in psoriatic arthritis patients receiving immunomodulatory therapy: results from a large multinational real-world study

Alten, R., Conaghan, P. G., Strand, V., Sullivan, E., Blackburn, S., Tian, H., Gandhi, K., Jugl, S. M. & Deodhar, A., Jun 1 2019, In : Clinical Rheumatology. 38, 6, p. 1615-1626 12 p.

Research output: Contribution to journalArticle

Utility of anakinra in acute crystalline diseases: A retrospective study comparing a university hospital with a veterans affairs medical center

Desmarais, J. & Chu, C-Q., Jan 1 2019, In : Journal of Rheumatology. 46, 7, p. 748-750 3 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

4-year results from the RAPID-PsA phase 3 randomised placebo-controlled trial of certolizumab pegol in psoriatic arthritis

Van Der Heijde, D., Deodhar, A., Fitzgerald, O., Fleischmann, R., Gladman, D., Gottlieb, A. B., Hoepken, B., Bauer, L., Irvin-Sellers, O., Khraishi, M., Peterson, L., Turkiewicz, A., Wollenhaupt, J. & Mease, P. J., Jan 1 2018, In : RMD Open. 4, 1, e000582.

Research output: Contribution to journalArticle

3 Scopus citations

Advances in spondyloarthritis: Glimpse in the future

Deodhar, A. A., Jul 1 2018, In : Current Opinion in Rheumatology. 30, 4, p. 301-302 2 p.

Research output: Contribution to journalEditorial

Axial spondyloarthritis in the USA: diagnostic challenges and missed opportunities

Danve, A. & Deodhar, A. A., Jan 1 2018, (Accepted/In press) In : Clinical Rheumatology.

Research output: Contribution to journalArticle

4 Scopus citations
13 Scopus citations

Complementary medicine for axial spondyloarthritis: Is there any scientific evidence?

Danve, A. & Deodhar, A. A., Jul 1 2018, In : Current Opinion in Rheumatology. 30, 4, p. 310-318 9 p.

Research output: Contribution to journalReview article

3 Scopus citations
Open Access
4 Scopus citations

Effects of HLA-B27 on Gut Microbiota in Experimental Spondyloarthritis Implicate an Ecological Model of Dysbiosis

Gill, T., Asquith, M., Brooks, S. R., Rosenbaum, J. J. & Colbert, R. A., Jan 1 2018, (Accepted/In press) In : Arthritis and Rheumatology.

Research output: Contribution to journalArticle

30 Scopus citations

Efficacy and safety of continuing versus withdrawing adalimumab therapy in maintaining remission in patients with non-radiographic axial spondyloarthritis (ABILITY-3): a multicentre, randomised, double-blind study

Landewé, R., Sieper, J., Mease, P., Inman, R. D., Lambert, R. G., Deodhar, A., Marzo-Ortega, H., Magrey, M., Kiltz, U., Wang, X., Li, M., Zhong, S., Mostafa, N. M., Lertratanakul, A., Pangan, A. L. & Anderson, J. K., Jul 14 2018, In : The Lancet. 392, 10142, p. 134-144 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Efficacy and safety of filgotinib, a selective Janus kinase 1 inhibitor, in patients with active ankylosing spondylitis (TORTUGA): results from a randomised, placebo-controlled, phase 2 trial

van der Heijde, D., Baraliakos, X., Gensler, L. S., Maksymowych, W. P., Tseluyko, V., Nadashkevich, O., Abi-Saab, W., Tasset, C., Meuleners, L., Besuyen, R., Hendrikx, T., Mozaffarian, N., Liu, K., Greer, J. M., Deodhar, A. & Landewé, R., Dec 1 2018, In : The Lancet. 392, 10162, p. 2378-2387 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Efficacy and safety of guselkumab in patients with active psoriatic arthritis: a randomised, double-blind, placebo-controlled, phase 2 study

CNTO1959PSA2001 Study Group, Jun 2 2018, In : The Lancet. 391, 10136, p. 2213-2224 12 p.

Research output: Contribution to journalArticle

37 Scopus citations