Research Output 1991 2019

2019

2019 Update of the American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis

Ward, M. M., Deodhar, A. A., Gensler, L. S., Dubreuil, M., Yu, D., Khan, M. A., Haroon, N., Borenstein, D., Wang, R., Biehl, A., Fang, M. A., Louie, G., Majithia, V., Ng, B., Bigham, R., Pianin, M., Shah, A. A., Sullivan, N., Turgunbaev, M., Oristaglio, J. & 3 others, Turner, A., Maksymowych, W. P. & Caplan, L., Jan 1 2019, (Accepted/In press) In : Arthritis Care and Research.

Research output: Contribution to journalArticle

Spondylitis
LY2439821
Ankylosing Spondylitis
Tumor Necrosis Factor-alpha
Research

2019 Update of the American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis

Ward, M. M., Deodhar, A. A., Gensler, L. S., Dubreuil, M., Yu, D., Khan, M. A., Haroon, N., Borenstein, D., Wang, R., Biehl, A., Fang, M. A., Louie, G., Majithia, V., Ng, B., Bigham, R., Pianin, M., Shah, A. A., Sullivan, N., Turgunbaev, M., Oristaglio, J. & 3 others, Turner, A., Maksymowych, W. P. & Caplan, L., Jan 1 2019, (Accepted/In press) In : Arthritis and Rheumatology.

Research output: Contribution to journalArticle

Spondylitis
LY2439821
Ankylosing Spondylitis
Tumor Necrosis Factor-alpha
Research

A Fifty-Two–Week, Randomized, Placebo-Controlled Trial of Certolizumab Pegol in Nonradiographic Axial Spondyloarthritis

Deodhar, A. A., Gensler, L. S., Kay, J., Maksymowych, W. P., Haroon, N., Landewé, R., Rudwaleit, M., Hall, S., Bauer, L., Hoepken, B., de Peyrecave, N., Kilgallen, B. & van der Heijde, D., Jul 1 2019, In : Arthritis and Rheumatology. 71, 7, p. 1101-1111 11 p.

Research output: Contribution to journalArticle

Open Access
Randomized Controlled Trials
Placebos
Ankylosing Spondylitis
Certolizumab Pegol
Therapeutics

Controlling for contaminants in low-biomass 16S rRNA gene sequencing experiments

Karstens, L., Asquith, M., Davin, S., Fair, D., Gregory, W. T., Wolfe, A. J., Braun, J. & McWeeney, S., Jul 1 2019, In : mSystems. 4, 4, e00290-19.

Research output: Contribution to journalArticle

Open Access
Biomass
rRNA Genes
Sequencing
microbial communities
Genes
1 Citation (Scopus)

Disruption of Intestinal Homeostasis and Intestinal Microbiota During Experimental Autoimmune Uveitis

Janowitz, C., Nakamura, Y. K., Metea, C., Gligor, A., Yu, W., Karstens, L., Rosenbaum, J. J., Asquith, M. & Lin, P., Jan 2 2019, In : Investigative ophthalmology & visual science. 60, 1, p. 420-429 10 p.

Research output: Contribution to journalArticle

Uveitis
Homeostasis
Permeability
Peptides
Dysbiosis
10 Citations (Scopus)
Open Access
LY2439821
Tumor Necrosis Factor-alpha
Placebos
Safety
Therapeutics
Antineutrophil Cytoplasmic Antibodies
Vasculitis
Pathology
Gene Expression
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

Harnessing the power of social media: how can it help in axial spondyloarthritis research?

Reuter, K., Danve, A. & Deodhar, A. A., Jul 1 2019, In : Current opinion in rheumatology. 31, 4, p. 321-328 8 p.

Research output: Contribution to journalArticle

Social Media
Research
Rheumatology
Education
Medical Education

HLA Alleles Associated With Risk of Ankylosing Spondylitis and Rheumatoid Arthritis Influence the Gut Microbiome

Asquith, M., Sternes, P. R., Costello, M. E., Karstens, L., Diamond, S., Martin, T., Li, Z., Marshall, M. S., Spector, T. D., le Cao, K. A., Rosenbaum, J. J. & Brown, M. A., Jan 1 2019, (Accepted/In press) In : Arthritis and Rheumatology.

Research output: Contribution to journalArticle

Ankylosing Spondylitis
Rheumatoid Arthritis
Alleles
Microbiota
Genotype
7 Citations (Scopus)

Incidence rates of inflammatory bowel disease in patients with psoriasis, psoriatic arthritis and ankylosing spondylitis treated with secukinumab: A retrospective analysis of pooled data from 21 clinical trials

Schreiber, S., Colombel, J. F., Feagan, B. G., Reich, K., Deodhar, A. A., McInnes, I. B., Porter, B., Das Gupta, A., Pricop, L. & Fox, T., Jan 1 2019, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

Psoriatic Arthritis
Ankylosing Spondylitis
Inflammatory Bowel Diseases
Psoriasis
Clinical Trials
2 Citations (Scopus)

Long-term safety of secukinumab in patients with moderate-to-severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis: Integrated pooled clinical trial and post-marketing surveillance data

Deodhar, A. A., Mease, P. J., McInnes, I. B., Baraliakos, X., Reich, K., Blauvelt, A., Leonardi, C., Porter, B., Das Gupta, A., Widmer, A., Pricop, L. & Fox, T., May 2 2019, In : Arthritis Research and Therapy. 21, 1, 111.

Research output: Contribution to journalArticle

Open Access
Psoriatic Arthritis
Ankylosing Spondylitis
Marketing
Psoriasis
Clinical Trials

Measuring Coaching in Undergraduate Medical Education: the Development and Psychometric Validation of New Instruments

Carney, P. P., Bonura, E. M., Kraakevik, J., Juve, A. M., Kahl, L. & Deiorio, N., May 15 2019, In : Journal of general internal medicine. 34, 5, p. 677-683 7 p.

Research output: Contribution to journalArticle

Undergraduate Medical Education
Psychometrics
Medical Students
Mentoring
Educational Measurement
2 Citations (Scopus)

Modified stoke ankylosing spondylitis spinal score as an outcome measure to assess the impact of treatment on structural progression in ankylosing spondylitis

Van Der Heijde, D., Braun, J., Deodhar, A. A., Baraliakos, X., Landewé, R., Richards, H. B., Porter, B. & Readie, A., Mar 1 2019, In : Rheumatology (United Kingdom). 58, 3, p. 388-400 13 p.

Research output: Contribution to journalReview article

Open Access
Ankylosing Spondylitis
Outcome Assessment (Health Care)
Therapeutics
Ankylosis
Biological Therapy
1 Citation (Scopus)
Open Access
Zygapophyseal Joint
Antisense Oligonucleotides
Chondrocytes
Knee Joint
MicroRNAs
Nephrotic Syndrome
Adrenocorticotropic Hormone
Glucocorticoids
Kidney
Costs and Cost Analysis
2 Citations (Scopus)
Ankylosing Spondylitis
C-Reactive Protein
Fatigue
Tumor Necrosis Factor-alpha
Pain
5 Citations (Scopus)

Secukinumab shows sustained efficacy and low structural progression in ankylosing spondylitis: 4-year results from the MEASURE 1 study

Braun, J., Baraliakos, X., Deodhar, A. A., Poddubnyy, D., Emery, P., Delicha, E. M., Talloczy, Z. & Porter, B., May 1 2019, In : Rheumatology (United Kingdom). 58, 5, p. 859-868 10 p.

Research output: Contribution to journalArticle

Open Access
Ankylosing Spondylitis
Safety
Berlin
Infection
secukinumab

Silencing RORγt in Human CD4+ T cells with CD30 aptamer-RORγt shRNA Chimera

Shi, X., Song, P., Tao, S., Zhang, X. & Chu, C-Q., Dec 1 2019, In : Scientific Reports. 9, 1, 10375.

Research output: Contribution to journalArticle

Open Access
Interleukin-17
Small Interfering RNA
T-Lymphocytes
Th17 Cells
Nucleotide Aptamers
11 Citations (Scopus)

Special Article: 2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis

Singh, J. A., Guyatt, G., Ogdie, A., Gladman, D. D., Deal, C., Deodhar, A. A., Dubreuil, M., Dunham, J., Husni, M. E., Kenny, S., Kwan-Morley, J., Lin, J., Marchetta, P., Mease, P. J., Merola, J. F., Miner, J., Ritchlin, C. T., Siaton, B., Smith, B. J., Van Voorhees, A. S. & 16 others, Jonsson, A. H., Shah, A. A., Sullivan, N., Turgunbaev, M., Coates, L. C., Gottlieb, A., Magrey, M., Nowell, W. B., Orbai, A. M., Reddy, S. M., Scher, J. U., Siegel, E., Siegel, M., Walsh, J. A., Turner, A. S. & Reston, J., Jan 1 2019, In : Arthritis Care and Research. 71, 1, p. 2-29 28 p.

Research output: Contribution to journalArticle

Psoriatic Arthritis
Psoriasis
Guidelines
Therapeutics
Health Personnel
12 Citations (Scopus)

Special Article: 2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis

Singh, J. A., Guyatt, G., Ogdie, A., Gladman, D. D., Deal, C., Deodhar, A. A., Dubreuil, M., Dunham, J., Husni, M. E., Kenny, S., Kwan-Morley, J., Lin, J., Marchetta, P., Mease, P. J., Merola, J. F., Miner, J., Ritchlin, C. T., Siaton, B., Smith, B. J., Van Voorhees, A. S. & 16 others, Jonsson, A. H., Shah, A. A., Sullivan, N., Turgunbaev, M., Coates, L. C., Gottlieb, A., Magrey, M., Nowell, W. B., Orbai, A. M., Reddy, S. M., Scher, J. U., Siegel, E., Siegel, M., Walsh, J. A., Turner, A. S. & Reston, J., Jan 1 2019, In : Arthritis and Rheumatology. 71, 1, p. 5-32 28 p.

Research output: Contribution to journalArticle

Psoriatic Arthritis
Psoriasis
Guidelines
Therapeutics
Health Personnel
13 Citations (Scopus)

Three Multicenter, Randomized, Double-Blind, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Ustekinumab in Axial Spondyloarthritis

Deodhar, A. A., Gensler, L. S., Sieper, J., Clark, M., Calderon, C., Wang, Y., Zhou, Y., Leu, J. H., Campbell, K., Sweet, K., Harrison, D. D., Hsia, E. C. & van der Heijde, D., Jan 1 2019, (Accepted/In press) In : Arthritis and Rheumatology.

Research output: Contribution to journalArticle

Placebos
Safety
Necrosis
Ustekinumab

Treat-to-target in axial spondyloarthritis: gold standard or fools' gold?

Machado, P. M. & Deodhar, A. A., Jul 1 2019, In : Current opinion in rheumatology. 31, 4, p. 344-348 5 p.

Research output: Contribution to journalArticle

Gold
Ankylosing Spondylitis
Psoriatic Arthritis
Gout
Hypothyroidism

Unmet needs in psoriatic arthritis patients receiving immunomodulatory therapy: results from a large multinational real-world study

Alten, R., Conaghan, P. G., Strand, V., Sullivan, E., Blackburn, S., Tian, H., Gandhi, K., Jugl, S. M. & Deodhar, A. A., Jan 1 2019, In : Clinical Rheumatology.

Research output: Contribution to journalArticle

Psoriatic Arthritis
Immunomodulation
ametantrone
Quality of Life
Treatment Failure

Use of machine learning techniques in the development and refinement of a predictive model for early diagnosis of ankylosing spondylitis

Deodhar, A. A., Rozycki, M., Garges, C., Shukla, O., Arndt, T., Grabowsky, T. & Park, Y., Jan 1 2019, In : Clinical Rheumatology.

Research output: Contribution to journalArticle

Open Access
Ankylosing Spondylitis
Early Diagnosis
Linear Models
Machine Learning
Databases
1 Citation (Scopus)

Utility of anakinra in acute crystalline diseases: A retrospective study comparing a university hospital with a veterans affairs medical center

Desmarais, J. & Chu, C-Q., Jan 1 2019, In : Journal of Rheumatology. 46, 7, p. 748-750 3 p.

Research output: Contribution to journalArticle

Chondrocalcinosis
Interleukin 1 Receptor Antagonist Protein
Gout
Acute Disease
Veterans
2018
1 Citation (Scopus)

4-year results from the RAPID-PsA phase 3 randomised placebo-controlled trial of certolizumab pegol in psoriatic arthritis

Van Der Heijde, D., Deodhar, A. A., Fitzgerald, O., Fleischmann, R., Gladman, D., Gottlieb, A. B., Hoepken, B., Bauer, L., Irvin-Sellers, O., Khraishi, M., Peterson, L., Turkiewicz, A., Wollenhaupt, J. & Mease, P. J., Jan 1 2018, In : RMD Open. 4, 1, e000582.

Research output: Contribution to journalArticle

Psoriatic Arthritis
Randomized Controlled Trials
Placebos
Safety
Psoriasis

Advances in spondyloarthritis: Glimpse in the future

Deodhar, A. A., Jul 1 2018, In : Current Opinion in Rheumatology. 30, 4, p. 301-302 2 p.

Research output: Contribution to journalEditorial

3 Citations (Scopus)

Axial spondyloarthritis in the USA: diagnostic challenges and missed opportunities

Danve, A. & Deodhar, A. A., Jan 1 2018, (Accepted/In press) In : Clinical Rheumatology.

Research output: Contribution to journalArticle

Back Pain
Sacroiliitis
Sacroiliac Joint
Chiropractic
Pain Clinics
1 Citation (Scopus)
Microbiota
Biomass
Urinary Tract
Vagina
Urinary Tract Infections
2 Citations (Scopus)

Complementary medicine for axial spondyloarthritis: Is there any scientific evidence?

Danve, A. & Deodhar, A. A., Jul 1 2018, In : Current Opinion in Rheumatology. 30, 4, p. 310-318 9 p.

Research output: Contribution to journalReview article

Complementary Therapies
Yoga
Tai Ji
Clinical Trials
Safety Management
2 Citations (Scopus)
Open Access
Psoriatic Arthritis
Randomized Controlled Trials
Placebos
Certolizumab Pegol
17 Citations (Scopus)

Effects of HLA-B27 on Gut Microbiota in Experimental Spondyloarthritis Implicate an Ecological Model of Dysbiosis

Gill, T., Asquith, M., Brooks, S. R., Rosenbaum, J. J. & Colbert, R. A., Jan 1 2018, (Accepted/In press) In : Arthritis and Rheumatology.

Research output: Contribution to journalArticle

Dysbiosis
HLA-B27 Antigen
Transgenic Rats
Inbred F344 Rats
HLA-B7 Antigen
7 Citations (Scopus)

Efficacy and safety of continuing versus withdrawing adalimumab therapy in maintaining remission in patients with non-radiographic axial spondyloarthritis (ABILITY-3): a multicentre, randomised, double-blind study

Landewé, R., Sieper, J., Mease, P., Inman, R. D., Lambert, R. G., Deodhar, A. A., Marzo-Ortega, H., Magrey, M., Kiltz, U., Wang, X., Li, M., Zhong, S., Mostafa, N. M., Lertratanakul, A., Pangan, A. L. & Anderson, J. K., Jan 1 2018, (Accepted/In press) In : The Lancet.

Research output: Contribution to journalArticle

Double-Blind Method
Safety
Therapeutics
Placebos
Adalimumab
20 Citations (Scopus)

Efficacy and safety of filgotinib, a selective Janus kinase 1 inhibitor, in patients with active ankylosing spondylitis (TORTUGA): results from a randomised, placebo-controlled, phase 2 trial

van der Heijde, D., Baraliakos, X., Gensler, L. S., Maksymowych, W. P., Tseluyko, V., Nadashkevich, O., Abi-Saab, W., Tasset, C., Meuleners, L., Besuyen, R., Hendrikx, T., Mozaffarian, N., Liu, K., Greer, J. M., Deodhar, A. A. & Landewé, R., Jan 1 2018, (Accepted/In press) In : The Lancet.

Research output: Contribution to journalArticle

Janus Kinase 1
Ankylosing Spondylitis
Placebos
Safety
Therapeutics
17 Citations (Scopus)

Efficacy and safety of guselkumab in patients with active psoriatic arthritis: a randomised, double-blind, placebo-controlled, phase 2 study

CNTO1959PSA2001 Study Group, Jun 2 2018, In : The Lancet. 391, 10136, p. 2213-2224 12 p.

Research output: Contribution to journalArticle

Psoriatic Arthritis
Placebos
Safety
guselkumab
Psoriasis
1 Citation (Scopus)

Elephant in the room

Hartung, D. M., Johnston, K., Cohen, D., Nguyen, T., Deodhar, A. A. & Bourdette, D., Jan 23 2018, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

Polymyositis
Dermatomyositis
Adrenal Cortex Hormones
4 Citations (Scopus)

Fecal transplants in spondyloarthritis and uveitis: Ready for a clinical trial?

Choi, R. Y., Asquith, M. & Rosenbaum, J. J., Jul 1 2018, In : Current Opinion in Rheumatology. 30, 4, p. 303-309 7 p.

Research output: Contribution to journalReview article

Uveitis
Clinical Trials
Inflammatory Bowel Diseases
Dysbiosis
Inborn Genetic Diseases
3 Citations (Scopus)

Impact of baseline C-reactive protein levels on the response to secukinumab in ankylosing spondylitis: 3-year pooled data from two phase III studies

Braun, J., Deodhar, A. A., Landewé, R., Baraliakos, X., Miceli-Richard, C., Sieper, J., Quebe-Fehling, E., Martin, R., Porter, B., Gandhi, K. K. & Van Der Heijde, D., Nov 1 2018, In : RMD Open. 4, 2, e000749.

Research output: Contribution to journalArticle

Ankylosing Spondylitis
C-Reactive Protein
Placebos
secukinumab
Baths
2 Citations (Scopus)

Incidence and prevalence of axial spondyloarthritis: Methodologic challenges and gaps in the literature

Bohn, R., Cooney, M., Deodhar, A. A., Curtis, J. R. & Golembesky, A., Jan 1 2018, In : Clinical and Experimental Rheumatology. 36, 2, p. 263-274 12 p.

Research output: Contribution to journalArticle

Ankylosing Spondylitis
Incidence
Population
HLA-B27 Antigen
Iceland
1 Citation (Scopus)
LY2439821
Psoriatic Arthritis
Antirheumatic Agents
Tumor Necrosis Factor-alpha
Placebos
25 Citations (Scopus)
Interleukin-17
Ankylosing Spondylitis
Safety
Signs and Symptoms
Therapeutics
1 Citation (Scopus)

Mirror, mirror, on the wall, which is the most effective biologic of all?

Deodhar, A. A., Apr 1 2018, In : Journal of Rheumatology. 45, 4, p. 449-450 2 p.

Research output: Contribution to journalEditorial

4 Citations (Scopus)

Nod2 deficiency augments Th17 responses and exacerbates autoimmune arthritis

Napier, R. J., Lee, E., Vance, E. E., Snow, P. E., Samson, K. A., Dawson, C. E., Moran, A., Stenzel, P., Davey, M., Sakaguchi, S. & Rosenzweig, H., Oct 1 2018, In : Journal of Immunology. 201, 7, p. 1889-1898 10 p.

Research output: Contribution to journalArticle

Autoimmunity
Arthritis
T-Lymphocytes
Interleukin-17
Th17 Cells

Plasma D-dimer is a promising indicator for the treatment of acute gouty attack

Wu, Y., Chu, C-Q., Song, P., Yang, Y., Lin, C. & Xu, Q., Jul 1 2018, In : Annals of Clinical and Laboratory Science. 48, 4, p. 435-439 5 p.

Research output: Contribution to journalArticle

Gout
Plasmas
Sedimentation
Blood Sedimentation
Blood
Psoriatic Arthritis
Psoriasis
Quality of Life
Patient Reported Outcome Measures
Mental Health
4 Citations (Scopus)

Safety and efficacy of golimumab administered intravenously in adults with ankylosing spondylitis: Results through week 28 of the GO-ALIVE study

Deodhar, A. A., Reveille, J. D., Harrison, D. D., Kim, L., Lo, K. H., Leu, J. H. & Hsia, E. C., Mar 1 2018, In : Journal of Rheumatology. 45, 3, p. 341-348 8 p.

Research output: Contribution to journalArticle

Ankylosing Spondylitis
Safety
Baths
Placebos
golimumab
6 Citations (Scopus)

Secukinumab in pregnancy: outcomes in psoriasis, psoriatic arthritis and ankylosing spondylitis from the global safety database

Warren, R. B., Reich, K., Langley, R. G., Strober, B., Gladman, D., Deodhar, A. A., Bachhuber, T., Bao, W., Altemeyer, E., Hussain, S. & Safi, J., Nov 1 2018, In : British Journal of Dermatology. 179, 5, p. 1205-1207 3 p.

Research output: Contribution to journalLetter

Psoriatic Arthritis
Ankylosing Spondylitis
Pregnancy Outcome
Psoriasis
Databases
2 Citations (Scopus)

Spondyloarthritis, acute anterior uveitis, and fungi: Updating the Catterall-King hypothesis

Laurence, M., Asquith, M. & Rosenbaum, J. J., Apr 1 2018, In : Frontiers in Medicine. 5, APR, 80.

Research output: Contribution to journalArticle

Open Access
Anterior Uveitis
Psoriasis
Multiple Sclerosis
Fungi
Mycoses